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The map label for this gene is ntrB [H]

Identifier: 148653958

GI number: 148653958

Start: 2697199

End: 2699007

Strand: Direct

Name: ntrB [H]

Synonym: PsycPRwf_2161

Alternate gene names: 148653958

Gene position: 2697199-2699007 (Clockwise)

Preceding gene: 148653957

Following gene: 148653961

Centisome position: 90.54

GC content: 47.87

Gene sequence:

>1809_bases
ATGCCCCGACTGCCTCGATTTGGTTTTACCTCTGTTTTTAATAAGCTATTTACCAGTGTGGTGTTGACGCTGGTTTTTTT
TGCGGCGGCCATGATTACTTTGATGAACATGGTGCACAACAACTCTGCAGATGCAAGATGGGAGGTACTGGCAAAACAAA
TTGTCAGCCAAGTTGACCCGTTTATTGACGAATTAGACAATGCCACTACCATGAACGAGCTGTTACAGGCCCGATTTATG
CTGGCTGTCATAAAAAAAAGCTTCGATGTTTTTGATGAATCCCTACAAGCCAAAATGGGGCTTTATGACCGCAAGGGTCA
TTTGTTAATTCAAACTGACGATAGCGACTTGCCCAAGACCCTACCCGAGGACCCCTCGTTAATCTCGCGTATGCTACCGG
CTTTTTTCTCCTCGGATCAGGTGAACGTGCAGGCCATGAGTGATCGTGGCTATACCTTGCTGTATGAGCCACGCAATCCC
CCAAAACGCTCTGAATTATGGGCGGTACTTAATATATTCACCGGTACTTTGGCCTTAATTGGTCTGATGTCGGCCGTGCT
GTGGTGGATTGCGCACTCTATGACCTGGCGCATTAATCAGATGAGCAAACAGATGGCTCAGCTTGGTGAGGGTAATTTTA
GTGTGCGGGTGCCTGCCAAAGGGACGGATGAGATTGCCAGTCTGGCACGCGGCTTCAACCAAGCAGCACAAAAAATTGAG
CAGCTTATCAATGCCAATAATCTATTGCTGGCGCATGCTTCACATGAGCTGCGCACACCCATTACTCGTATTCGCCTGCA
GATTGAGATGATGGAGATGCTGTCTAATGAGATGTCCGAGGGCACCAAAGCCAAGTTCCATAAACGGGCACAAGCTGTCA
ATCGTGACCTCACTGGCCTCAATGACTTGGTGGAGAGTATCTTACTGGTGAGCCGCTTAGATGCCGGTCACGCTGCCCAA
GCAAATGAACGCTTTGACTTTTTTGAACTGGTCAATCAAGAGTGCCAGCATTACCCTGAGGCCACTTTATACGGCAAATC
TTTGGTAATTGAAGGTCAGCCTAAGTTGCTGATTCATTTGATACGCAATCTTTTAAATAATGCCCTTATCCATGGTCAGC
CGCCCATTGAAGTGCATGTTTACGGCGTGGTCAATCAAAAAGATGCGCTGTATCCGCCCAAACAGCTGCTGGATCAAATT
GCGCTATCACATGCTGAAGATGAGCTAGAAGTGTTAGAGGACTTAGCCGAATACGAGAGTGAGGCGAATTTACCAGCGCT
CAGCACAGAGCTGGCAAGTGAGGAGGCAGATCAATCGCCTGAGCAAGATGAGGATGAGCACCAAAGCCTAATCTCTGACG
CTCAAGAGGTCGCCGATGACCAAAGCGCAGACAGCACACCCAATACAGTCGCTGCTAAAGAGGCAGATGAAGGTAAAGAT
AAGGCCGACAAGCTCAAAAAAGTCGATAAAAAAGCAAAGTCTGAGAGCTCTAAGCTCAATGACATGAGCTTTGCCAAACG
CTTACGCCGGCCAAAAGCTGAGCCCATTGCCCAGCCCAACTATGTGGTATTGGCGGTGATAGACCAAGGTAAAGGCATTC
CAGTTGATAAGCGTGAGGAAATATTTAGTCCCTTTGTGCGTCTACAGCAGCAAAAGAAAGGGTCAGGACTAGGTCTATCC
TTGGTGGCACAAATTGTAGAGGCACATAATGGTCGCATCCGCACCGATACCTATAATGGTCGTACCCGCTTTATCGTGCT
GTTACCGGTCAATGATAAGGTGACGGTGGAGAAACCGAGTTTTTCTTAA

Upstream 100 bases:

>100_bases
CAATTGATATTCTACGGTTGATATCTACCATCCATTGAGGGTCTAAGCACAACCGGTTGGCTTAGACCCTCAATTACTCT
CATCTAGATTAGATAAGCTT

Downstream 100 bases:

>100_bases
TAAAAAATGCCCTGCTATTACCTCACGTAAGCTTACGGATCACCTGAGGGACACGGACGGTGATACGACTCGCTGCTACT
CTACTGGGGTAATTGTCATT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MPRLPRFGFTSVFNKLFTSVVLTLVFFAAAMITLMNMVHNNSADARWEVLAKQIVSQVDPFIDELDNATTMNELLQARFM
LAVIKKSFDVFDESLQAKMGLYDRKGHLLIQTDDSDLPKTLPEDPSLISRMLPAFFSSDQVNVQAMSDRGYTLLYEPRNP
PKRSELWAVLNIFTGTLALIGLMSAVLWWIAHSMTWRINQMSKQMAQLGEGNFSVRVPAKGTDEIASLARGFNQAAQKIE
QLINANNLLLAHASHELRTPITRIRLQIEMMEMLSNEMSEGTKAKFHKRAQAVNRDLTGLNDLVESILLVSRLDAGHAAQ
ANERFDFFELVNQECQHYPEATLYGKSLVIEGQPKLLIHLIRNLLNNALIHGQPPIEVHVYGVVNQKDALYPPKQLLDQI
ALSHAEDELEVLEDLAEYESEANLPALSTELASEEADQSPEQDEDEHQSLISDAQEVADDQSADSTPNTVAAKEADEGKD
KADKLKKVDKKAKSESSKLNDMSFAKRLRRPKAEPIAQPNYVVLAVIDQGKGIPVDKREEIFSPFVRLQQQKKGSGLGLS
LVAQIVEAHNGRIRTDTYNGRTRFIVLLPVNDKVTVEKPSFS

Sequences:

>Translated_602_residues
MPRLPRFGFTSVFNKLFTSVVLTLVFFAAAMITLMNMVHNNSADARWEVLAKQIVSQVDPFIDELDNATTMNELLQARFM
LAVIKKSFDVFDESLQAKMGLYDRKGHLLIQTDDSDLPKTLPEDPSLISRMLPAFFSSDQVNVQAMSDRGYTLLYEPRNP
PKRSELWAVLNIFTGTLALIGLMSAVLWWIAHSMTWRINQMSKQMAQLGEGNFSVRVPAKGTDEIASLARGFNQAAQKIE
QLINANNLLLAHASHELRTPITRIRLQIEMMEMLSNEMSEGTKAKFHKRAQAVNRDLTGLNDLVESILLVSRLDAGHAAQ
ANERFDFFELVNQECQHYPEATLYGKSLVIEGQPKLLIHLIRNLLNNALIHGQPPIEVHVYGVVNQKDALYPPKQLLDQI
ALSHAEDELEVLEDLAEYESEANLPALSTELASEEADQSPEQDEDEHQSLISDAQEVADDQSADSTPNTVAAKEADEGKD
KADKLKKVDKKAKSESSKLNDMSFAKRLRRPKAEPIAQPNYVVLAVIDQGKGIPVDKREEIFSPFVRLQQQKKGSGLGLS
LVAQIVEAHNGRIRTDTYNGRTRFIVLLPVNDKVTVEKPSFS
>Mature_601_residues
PRLPRFGFTSVFNKLFTSVVLTLVFFAAAMITLMNMVHNNSADARWEVLAKQIVSQVDPFIDELDNATTMNELLQARFML
AVIKKSFDVFDESLQAKMGLYDRKGHLLIQTDDSDLPKTLPEDPSLISRMLPAFFSSDQVNVQAMSDRGYTLLYEPRNPP
KRSELWAVLNIFTGTLALIGLMSAVLWWIAHSMTWRINQMSKQMAQLGEGNFSVRVPAKGTDEIASLARGFNQAAQKIEQ
LINANNLLLAHASHELRTPITRIRLQIEMMEMLSNEMSEGTKAKFHKRAQAVNRDLTGLNDLVESILLVSRLDAGHAAQA
NERFDFFELVNQECQHYPEATLYGKSLVIEGQPKLLIHLIRNLLNNALIHGQPPIEVHVYGVVNQKDALYPPKQLLDQIA
LSHAEDELEVLEDLAEYESEANLPALSTELASEEADQSPEQDEDEHQSLISDAQEVADDQSADSTPNTVAAKEADEGKDK
ADKLKKVDKKAKSESSKLNDMSFAKRLRRPKAEPIAQPNYVVLAVIDQGKGIPVDKREEIFSPFVRLQQQKKGSGLGLSL
VAQIVEAHNGRIRTDTYNGRTRFIVLLPVNDKVTVEKPSFS

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789808, Length=212, Percent_Identity=26.4150943396226, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787894, Length=180, Percent_Identity=29.4444444444444, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67409; Mature: 67278

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLPRFGFTSVFNKLFTSVVLTLVFFAAAMITLMNMVHNNSADARWEVLAKQIVSQVDP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FIDELDNATTMNELLQARFMLAVIKKSFDVFDESLQAKMGLYDRKGHLLIQTDDSDLPKT
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEEECCCCCCCC
LPEDPSLISRMLPAFFSSDQVNVQAMSDRGYTLLYEPRNPPKRSELWAVLNIFTGTLALI
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
GLMSAVLWWIAHSMTWRINQMSKQMAQLGEGNFSVRVPAKGTDEIASLARGFNQAAQKIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
QLINANNLLLAHASHELRTPITRIRLQIEMMEMLSNEMSEGTKAKFHKRAQAVNRDLTGL
HHHCCCCEEEEECCCHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCH
NDLVESILLVSRLDAGHAAQANERFDFFELVNQECQHYPEATLYGKSLVIEGQPKLLIHL
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCEEEECCCHHHHHHH
IRNLLNNALIHGQPPIEVHVYGVVNQKDALYPPKQLLDQIALSHAEDELEVLEDLAEYES
HHHHHHCCEECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EANLPALSTELASEEADQSPEQDEDEHQSLISDAQEVADDQSADSTPNTVAAKEADEGKD
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCC
KADKLKKVDKKAKSESSKLNDMSFAKRLRRPKAEPIAQPNYVVLAVIDQGKGIPVDKREE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHH
IFSPFVRLQQQKKGSGLGLSLVAQIVEAHNGRIRTDTYNGRTRFIVLLPVNDKVTVEKPS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEEEECCCCEEECCCC
FS
CC
>Mature Secondary Structure 
PRLPRFGFTSVFNKLFTSVVLTLVFFAAAMITLMNMVHNNSADARWEVLAKQIVSQVDP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FIDELDNATTMNELLQARFMLAVIKKSFDVFDESLQAKMGLYDRKGHLLIQTDDSDLPKT
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEEECCCCCCCC
LPEDPSLISRMLPAFFSSDQVNVQAMSDRGYTLLYEPRNPPKRSELWAVLNIFTGTLALI
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
GLMSAVLWWIAHSMTWRINQMSKQMAQLGEGNFSVRVPAKGTDEIASLARGFNQAAQKIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
QLINANNLLLAHASHELRTPITRIRLQIEMMEMLSNEMSEGTKAKFHKRAQAVNRDLTGL
HHHCCCCEEEEECCCHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCH
NDLVESILLVSRLDAGHAAQANERFDFFELVNQECQHYPEATLYGKSLVIEGQPKLLIHL
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCEEEECCCHHHHHHH
IRNLLNNALIHGQPPIEVHVYGVVNQKDALYPPKQLLDQIALSHAEDELEVLEDLAEYES
HHHHHHCCEECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EANLPALSTELASEEADQSPEQDEDEHQSLISDAQEVADDQSADSTPNTVAAKEADEGKD
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCC
KADKLKKVDKKAKSESSKLNDMSFAKRLRRPKAEPIAQPNYVVLAVIDQGKGIPVDKREE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHH
IFSPFVRLQQQKKGSGLGLSLVAQIVEAHNGRIRTDTYNGRTRFIVLLPVNDKVTVEKPS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEEEECCCCEEECCCC
FS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2710108; 8355615 [H]