Click here to switch to the map view.

The map label for this gene is yngI [H]

Identifier: 148653908

GI number: 148653908

Start: 2634649

End: 2636331

Strand: Direct

Name: yngI [H]

Synonym: PsycPRwf_2111

Alternate gene names: 148653908

Gene position: 2634649-2636331 (Clockwise)

Preceding gene: 148653906

Following gene: 148653914

Centisome position: 88.44

GC content: 48.31

Gene sequence:

>1683_bases
ATGACCGATTATACTACCGGTTTAGGCAAAACCGAGGCCAATCACCAGCCGCTCACGCCCTTACAATTCCTAACTCGCGC
CGCTTCGGTCTATCCTCATAAAACCTCTATCATTTATGATGATTTAGTCAACACGCCCATTACCTATACCTGGTCTCAAA
CCTTTGAGCGCTGCCGTAAATTGGCCCACGCCCTGCGCAAGCTTGGTATTGGCAAAGAAGATACTGTGGCCATTATGGCA
CCCAATACACCGGCCATGGTGGAAGCCGCTTTTGGAGTACCTATGTCGCAAGGGGTACTGTGTACTCTAAATACGCGTTT
AGACATCAATGCCCTCACCTTTTGTTTGCAGCACTCCGAAGCCAAAGTATTGATCATTGACAGCGAATACGCTCATCATG
TAGAGCTTATAGAAGAAACCTTCCCCAACTTAATCCTCATTCACGCCACCGACATGACGCTGCCTGATGTGCCTGCTTTT
GGCAAAATGAGCTATGAGGCACTCTTACAAAGCGGTGAGTTTGACTCTGATGAGGCAATCAGAGCCTTTGATGGCACCAT
CTATCCCACCGATGAGTGGGATGCCATTGCTCTTAATTACACTTCAGGTACCACCGGCAAGCCCAAAGGCGTGGTCTATC
ATCACCGCGGCGCTACTTTGAATGCGCTGTCAAATATTTTAGATTGGGACATGCCCAAGCATACCACCTACTTATGGACC
TTGCCCTTGTTCCATTGTAACGGTTGGTGTTTTCCTTGGACAGTCGCTGAGCGTGCTGGTATTAACGTCTGCTTACGTCA
AATCGATGCCAATTTAATCCTAAAACTCATTGCCAAATATCAGATTACTCATTACTGCGCCGCCCCCATTGTGCATAATA
TGATCGCGGCAGGTGATAGCCAGTTACAGCAAGCCATTAACCATAATGTGAAAGGCTTTGTGGCCGGTGCGCCGCCTTCT
GAGGCCATGCTCGAGAAGATGGAGGCGATGAACTTTAATGTCACTCATGTGTATGGTCTCACTGAGGTCTACGGGCCGGT
GACCATCTGTGCTGAGCATGATGAATGGCAACAGCTTTCGGTGTCAGAACGTGCTGCCAAAAAATCGCGTCAAGGTGTGG
TGTCACACTTAATGAGCGGCTTTGAGGTATTCAAACAAGGCACCACCGAGCCGGTTGCTGCTGATGCAACTGAGATGGGC
GAGCTGGCCTTAAAGGGCAACATGGTTATGAAAGGCTATTTAAAAAACCCCAAAGCGACCAAAGAGGCGTTTGCAGGCGG
CTGGTTCCGTACCGGAGACTTGGGCGTCAAATACCCAGATGGCTATATCAAAATTATGGATCGCCTAAAAGATATTATTA
TCTCAGGAGGCGAGAACATCTCAAGTATTGAGATTGAAAACACCTTATACAAAATGCCTGAGGTGAGTAGCTGCGGCGTG
GTGGCAGCCTCCAATGATAAGTGGGGAGAGGTGCCTGTGGCCTTCATCGAAATAGCTGAGGGCGCAACTTTGACCCGTGA
TCAGGTTATTGAGCATTGTCGTCAGCATCTGGCCAAGTTTAAAGTGCCCAAACATGTGATTTTCTGTGAAATTCCTAAAA
CCAGCACCGGAAAAATCCAAAAGTTTGAGCTGCGTAATGCCGCCCAATCTATGGCCAATGAAGAGCCCAAGGTAAAGTCT
TAG

Upstream 100 bases:

>100_bases
TAAGCTTATTTAGAGGGGTCGTGCAAAGGGTATGCAATGACCGCTTAGACATTTATGCTCAGATACCTAACTCAACATTT
CTGATAAAGGACTATCTTTT

Downstream 100 bases:

>100_bases
GCAGTATCCATACCTTATAGCCGCCATAGAAAACGCCAACGAGGAATGATTCGCTGGCGTTTTTTTAACTCTTACAATCA
GCCAATTAAGCAGCAGGCTG

Product: AMP-dependent synthetase and ligase

Products: D-carnitinyl-CoA; crotonobetainyl-CoA; L-carnitinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MTDYTTGLGKTEANHQPLTPLQFLTRAASVYPHKTSIIYDDLVNTPITYTWSQTFERCRKLAHALRKLGIGKEDTVAIMA
PNTPAMVEAAFGVPMSQGVLCTLNTRLDINALTFCLQHSEAKVLIIDSEYAHHVELIEETFPNLILIHATDMTLPDVPAF
GKMSYEALLQSGEFDSDEAIRAFDGTIYPTDEWDAIALNYTSGTTGKPKGVVYHHRGATLNALSNILDWDMPKHTTYLWT
LPLFHCNGWCFPWTVAERAGINVCLRQIDANLILKLIAKYQITHYCAAPIVHNMIAAGDSQLQQAINHNVKGFVAGAPPS
EAMLEKMEAMNFNVTHVYGLTEVYGPVTICAEHDEWQQLSVSERAAKKSRQGVVSHLMSGFEVFKQGTTEPVAADATEMG
ELALKGNMVMKGYLKNPKATKEAFAGGWFRTGDLGVKYPDGYIKIMDRLKDIIISGGENISSIEIENTLYKMPEVSSCGV
VAASNDKWGEVPVAFIEIAEGATLTRDQVIEHCRQHLAKFKVPKHVIFCEIPKTSTGKIQKFELRNAAQSMANEEPKVKS

Sequences:

>Translated_560_residues
MTDYTTGLGKTEANHQPLTPLQFLTRAASVYPHKTSIIYDDLVNTPITYTWSQTFERCRKLAHALRKLGIGKEDTVAIMA
PNTPAMVEAAFGVPMSQGVLCTLNTRLDINALTFCLQHSEAKVLIIDSEYAHHVELIEETFPNLILIHATDMTLPDVPAF
GKMSYEALLQSGEFDSDEAIRAFDGTIYPTDEWDAIALNYTSGTTGKPKGVVYHHRGATLNALSNILDWDMPKHTTYLWT
LPLFHCNGWCFPWTVAERAGINVCLRQIDANLILKLIAKYQITHYCAAPIVHNMIAAGDSQLQQAINHNVKGFVAGAPPS
EAMLEKMEAMNFNVTHVYGLTEVYGPVTICAEHDEWQQLSVSERAAKKSRQGVVSHLMSGFEVFKQGTTEPVAADATEMG
ELALKGNMVMKGYLKNPKATKEAFAGGWFRTGDLGVKYPDGYIKIMDRLKDIIISGGENISSIEIENTLYKMPEVSSCGV
VAASNDKWGEVPVAFIEIAEGATLTRDQVIEHCRQHLAKFKVPKHVIFCEIPKTSTGKIQKFELRNAAQSMANEEPKVKS
>Mature_559_residues
TDYTTGLGKTEANHQPLTPLQFLTRAASVYPHKTSIIYDDLVNTPITYTWSQTFERCRKLAHALRKLGIGKEDTVAIMAP
NTPAMVEAAFGVPMSQGVLCTLNTRLDINALTFCLQHSEAKVLIIDSEYAHHVELIEETFPNLILIHATDMTLPDVPAFG
KMSYEALLQSGEFDSDEAIRAFDGTIYPTDEWDAIALNYTSGTTGKPKGVVYHHRGATLNALSNILDWDMPKHTTYLWTL
PLFHCNGWCFPWTVAERAGINVCLRQIDANLILKLIAKYQITHYCAAPIVHNMIAAGDSQLQQAINHNVKGFVAGAPPSE
AMLEKMEAMNFNVTHVYGLTEVYGPVTICAEHDEWQQLSVSERAAKKSRQGVVSHLMSGFEVFKQGTTEPVAADATEMGE
LALKGNMVMKGYLKNPKATKEAFAGGWFRTGDLGVKYPDGYIKIMDRLKDIIISGGENISSIEIENTLYKMPEVSSCGVV
AASNDKWGEVPVAFIEIAEGATLTRDQVIEHCRQHLAKFKVPKHVIFCEIPKTSTGKIQKFELRNAAQSMANEEPKVKS

Specific function: Could Catalyze The Transfer Of CoA To Crotonobetaine Or Carnitine. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=590, Percent_Identity=25.9322033898305, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI157311624, Length=512, Percent_Identity=25.1953125, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI157311622, Length=512, Percent_Identity=25.1953125, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI38505220, Length=525, Percent_Identity=25.7142857142857, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI58082049, Length=535, Percent_Identity=23.9252336448598, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI42544132, Length=509, Percent_Identity=25.147347740668, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI187761345, Length=579, Percent_Identity=24.006908462867, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI187761343, Length=579, Percent_Identity=24.006908462867, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI115511026, Length=521, Percent_Identity=24.7600767754319, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI122937307, Length=519, Percent_Identity=25.8188824662813, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI13375727, Length=580, Percent_Identity=25.3448275862069, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI221142682, Length=534, Percent_Identity=25.4681647940075, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788107, Length=562, Percent_Identity=26.3345195729537, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI145693145, Length=360, Percent_Identity=28.3333333333333, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1786810, Length=509, Percent_Identity=25.5402750491159, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1789201, Length=487, Percent_Identity=21.1498973305955, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994694, Length=565, Percent_Identity=26.1946902654867, Blast_Score=159, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71994703, Length=565, Percent_Identity=26.1946902654867, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71994690, Length=565, Percent_Identity=26.1946902654867, Blast_Score=158, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17560308, Length=536, Percent_Identity=26.4925373134328, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17558820, Length=360, Percent_Identity=31.6666666666667, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17559526, Length=525, Percent_Identity=25.9047619047619, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32563687, Length=369, Percent_Identity=28.7262872628726, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17531443, Length=495, Percent_Identity=24.2424242424242, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17538037, Length=520, Percent_Identity=25.3846153846154, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17560140, Length=526, Percent_Identity=24.3346007604563, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17557194, Length=543, Percent_Identity=23.7569060773481, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71996755, Length=524, Percent_Identity=24.236641221374, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71985884, Length=360, Percent_Identity=28.6111111111111, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17510401, Length=485, Percent_Identity=23.2989690721649, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25147511, Length=587, Percent_Identity=22.1465076660988, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534440, Length=540, Percent_Identity=22.5925925925926, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319699, Length=497, Percent_Identity=26.5593561368209, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319264, Length=576, Percent_Identity=23.7847222222222, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581924, Length=535, Percent_Identity=25.0467289719626, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21355181, Length=537, Percent_Identity=24.7672253258845, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI18859661, Length=521, Percent_Identity=25.7197696737044, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17933690, Length=538, Percent_Identity=23.0483271375465, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21356947, Length=551, Percent_Identity=22.6860254083485, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI20130357, Length=552, Percent_Identity=24.8188405797101, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281365686, Length=508, Percent_Identity=22.0472440944882, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356441, Length=477, Percent_Identity=22.8511530398323, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21358303, Length=493, Percent_Identity=24.7464503042596, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24648255, Length=516, Percent_Identity=22.093023255814, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648253, Length=506, Percent_Identity=22.3320158102767, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648260, Length=504, Percent_Identity=21.4285714285714, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19921316, Length=168, Percent_Identity=30.3571428571429, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: 6.3.2.- [C]

Molecular weight: Translated: 61987; Mature: 61855

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDYTTGLGKTEANHQPLTPLQFLTRAASVYPHKTSIIYDDLVNTPITYTWSQTFERCRK
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHCCCCEEEEHHHHHHHHHH
LAHALRKLGIGKEDTVAIMAPNTPAMVEAAFGVPMSQGVLCTLNTRLDINALTFCLQHSE
HHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCC
AKVLIIDSEYAHHVELIEETFPNLILIHATDMTLPDVPAFGKMSYEALLQSGEFDSDEAI
CEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCHH
RAFDGTIYPTDEWDAIALNYTSGTTGKPKGVVYHHRGATLNALSNILDWDMPKHTTYLWT
HHHCCEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCEEEEE
LPLFHCNGWCFPWTVAERAGINVCLRQIDANLILKLIAKYQITHYCAAPIVHNMIAAGDS
EEEEECCCEEEECHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QLQQAINHNVKGFVAGAPPSEAMLEKMEAMNFNVTHVYGLTEVYGPVTICAEHDEWQQLS
HHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEECHHHHCCCEEEEECCCCHHHHH
VSERAAKKSRQGVVSHLMSGFEVFKQGTTEPVAADATEMGELALKGNMVMKGYLKNPKAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCEEEECCEEEEEECCCCCHH
KEAFAGGWFRTGDLGVKYPDGYIKIMDRLKDIIISGGENISSIEIENTLYKMPEVSSCGV
HHHHCCCCEEECCCCEECCCHHHHHHHHHHHHHHCCCCCCEEEEECHHHHCCCCCCCCCE
VAASNDKWGEVPVAFIEIAEGATLTRDQVIEHCRQHLAKFKVPKHVIFCEIPKTSTGKIQ
EEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEE
KFELRNAAQSMANEEPKVKS
EHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TDYTTGLGKTEANHQPLTPLQFLTRAASVYPHKTSIIYDDLVNTPITYTWSQTFERCRK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHCCCCEEEEHHHHHHHHHH
LAHALRKLGIGKEDTVAIMAPNTPAMVEAAFGVPMSQGVLCTLNTRLDINALTFCLQHSE
HHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCC
AKVLIIDSEYAHHVELIEETFPNLILIHATDMTLPDVPAFGKMSYEALLQSGEFDSDEAI
CEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCHH
RAFDGTIYPTDEWDAIALNYTSGTTGKPKGVVYHHRGATLNALSNILDWDMPKHTTYLWT
HHHCCEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCEEEEE
LPLFHCNGWCFPWTVAERAGINVCLRQIDANLILKLIAKYQITHYCAAPIVHNMIAAGDS
EEEEECCCEEEECHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QLQQAINHNVKGFVAGAPPSEAMLEKMEAMNFNVTHVYGLTEVYGPVTICAEHDEWQQLS
HHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEECHHHHCCCEEEEECCCCHHHHH
VSERAAKKSRQGVVSHLMSGFEVFKQGTTEPVAADATEMGELALKGNMVMKGYLKNPKAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCEEEECCEEEEEECCCCCHH
KEAFAGGWFRTGDLGVKYPDGYIKIMDRLKDIIISGGENISSIEIENTLYKMPEVSSCGV
HHHHCCCCEEECCCCEECCCHHHHHHHHHHHHHHCCCCCCEEEEECHHHHCCCCCCCCCE
VAASNDKWGEVPVAFIEIAEGATLTRDQVIEHCRQHLAKFKVPKHVIFCEIPKTSTGKIQ
EEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEE
KFELRNAAQSMANEEPKVKS
EHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; D-carnitine; Coenzyme A; crotono-betaine; L-carnitine [C]

Specific reaction: Coenzyme A + D-carnitine = D-carnitinyl-CoA Coenzyme A + crotono-betaine = crotonobetainyl-CoA Coenzyme A + L-carnitine = L-carnitinyl-CoA [C]

General reaction: Ligases; Forming Carbon-Sulfur Bonds; Acid-Thiol Ligases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]