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The map label for this gene is gltS [H]

Identifier: 148653877

GI number: 148653877

Start: 2594530

End: 2595804

Strand: Direct

Name: gltS [H]

Synonym: PsycPRwf_2080

Alternate gene names: 148653877

Gene position: 2594530-2595804 (Clockwise)

Preceding gene: 148653876

Following gene: 148653879

Centisome position: 87.09

GC content: 47.22

Gene sequence:

>1275_bases
ATGGAAGTTACTTTAAATGGCTACTATACGCTGATATTAGCCACACTCGTCCTACTCTTGGGACGGTTTTTGGTAAAAAG
GGTGAAGTTTTTAGAAGACTTTAACATCCCTGAGCCTGTGGCAGGTGGCTTGGTTGCAGCCGCCATTGTTTATGCACTTA
ATATCATATGGGGGTATAGTTTTAACTTCCAGCAGGAGCTTCAAACCGCTTGTATGCTGATGTTCTTCGCCTCAATCGGT
CTAAGCGCTGACTTTAGCCGCCTAAAAGCCGGTGGTTCCCCTCTATTAATCTTCACCATTGTGGTCTCAGTATTTATCAT
TTTGCAAGACGTGGTGGGTGTGACCATGGCCAGTGTATTGGGGCTTGATCCTCTGCTAGGTCTGGTGACAGGCTCTATTG
CGCTGACCGGTGGTCATGGTACTGCAGGCGCTTGGGGTATCACGCTTGAAGAGCAATACGGCGTGGTCGGTGCAACGACC
TTGGGTATCGCTGCGGCCACTTACGGTCTTGTTGCCGGTGGTGTGATTGGTGGCCCAGTAGCTCGCCGTTTAATCAACAG
ATTGGGTGTAAAACCAGGCGAGGTTAACCCCAACCCTACCCCGACTGAAAAGCTGGCCGGTGAGCAATCTTTATATAGCA
CCAAGCACAATGAAGAAGAAGCTTATCGCAATAAAGAGATCTTTGAGAAACCAGACAACATTCGTCTGATTACTGCCTCC
TCGACCATTGAGTCTTTGGCATTATTTGCAGCGTCATTAGCCTTTGCAGATATCATGACTAATTTGGGTCAAGGCACTTG
GTTTGAGCTGCCCACCTTCGTTTGGGCATTGGCTGGCGGTGTTATCTTGCGTAACGTATTGACCATGGTGTTTGACTTCC
ATATGTTTGACCGCGCCATTGACGTGATTGGTAACGCTTCATTAAGCCTATTTTTGGCAATGGCATTGTTGTCACTAAAA
CTTTGGCAGCTGACCGACCTTGCCGGCCCTGTATTGATTATCTTAGTAGTACAGACCTTAGTTATGATCGGTTATGCCTA
CTTGGTGACCTTTAGAATTATGGGTAAAGACTATGATTCTGCCGTTTTAGCAGCAGGTCACTGCGGCTTTGGGATGGGTG
CGACCCCGACTGCCATTGCCAACATGCAAGCGGTCACCGATCGTTATCAGCCTTCGCACAAAGCTTTCTTAATTGTGCCT
ATGGTAGGTGCTTTCTTTGTGGATATCGTCAACGCTACCGTATTACAGATTTTCACTAAATTACCGTTTATGTAA

Upstream 100 bases:

>100_bases
TACTATTTAAAGTCTAATGCACAAAGCAAACCTTATTTTGGAGCAGCTCATGCTGGAAATCCAATGAGGGTAACTTTATT
TTTATAAAAAGGAGCAACGA

Downstream 100 bases:

>100_bases
GAAAGTTTAGTACACGCTTAAATAACCTAAAAAAGGGAGAGATTTGCTTTAATCTCTCCCTTTTTTTATCTATTATGTTA
AATCTATAGCCTGATCGATT

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MEVTLNGYYTLILATLVLLLGRFLVKRVKFLEDFNIPEPVAGGLVAAAIVYALNIIWGYSFNFQQELQTACMLMFFASIG
LSADFSRLKAGGSPLLIFTIVVSVFIILQDVVGVTMASVLGLDPLLGLVTGSIALTGGHGTAGAWGITLEEQYGVVGATT
LGIAAATYGLVAGGVIGGPVARRLINRLGVKPGEVNPNPTPTEKLAGEQSLYSTKHNEEEAYRNKEIFEKPDNIRLITAS
STIESLALFAASLAFADIMTNLGQGTWFELPTFVWALAGGVILRNVLTMVFDFHMFDRAIDVIGNASLSLFLAMALLSLK
LWQLTDLAGPVLIILVVQTLVMIGYAYLVTFRIMGKDYDSAVLAAGHCGFGMGATPTAIANMQAVTDRYQPSHKAFLIVP
MVGAFFVDIVNATVLQIFTKLPFM

Sequences:

>Translated_424_residues
MEVTLNGYYTLILATLVLLLGRFLVKRVKFLEDFNIPEPVAGGLVAAAIVYALNIIWGYSFNFQQELQTACMLMFFASIG
LSADFSRLKAGGSPLLIFTIVVSVFIILQDVVGVTMASVLGLDPLLGLVTGSIALTGGHGTAGAWGITLEEQYGVVGATT
LGIAAATYGLVAGGVIGGPVARRLINRLGVKPGEVNPNPTPTEKLAGEQSLYSTKHNEEEAYRNKEIFEKPDNIRLITAS
STIESLALFAASLAFADIMTNLGQGTWFELPTFVWALAGGVILRNVLTMVFDFHMFDRAIDVIGNASLSLFLAMALLSLK
LWQLTDLAGPVLIILVVQTLVMIGYAYLVTFRIMGKDYDSAVLAAGHCGFGMGATPTAIANMQAVTDRYQPSHKAFLIVP
MVGAFFVDIVNATVLQIFTKLPFM
>Mature_424_residues
MEVTLNGYYTLILATLVLLLGRFLVKRVKFLEDFNIPEPVAGGLVAAAIVYALNIIWGYSFNFQQELQTACMLMFFASIG
LSADFSRLKAGGSPLLIFTIVVSVFIILQDVVGVTMASVLGLDPLLGLVTGSIALTGGHGTAGAWGITLEEQYGVVGATT
LGIAAATYGLVAGGVIGGPVARRLINRLGVKPGEVNPNPTPTEKLAGEQSLYSTKHNEEEAYRNKEIFEKPDNIRLITAS
STIESLALFAASLAFADIMTNLGQGTWFELPTFVWALAGGVILRNVLTMVFDFHMFDRAIDVIGNASLSLFLAMALLSLK
LWQLTDLAGPVLIILVVQTLVMIGYAYLVTFRIMGKDYDSAVLAAGHCGFGMGATPTAIANMQAVTDRYQPSHKAFLIVP
MVGAFFVDIVNATVLQIFTKLPFM

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=402, Percent_Identity=52.2388059701493, Blast_Score=355, Evalue=4e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 45476; Mature: 45476

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTLNGYYTLILATLVLLLGRFLVKRVKFLEDFNIPEPVAGGLVAAAIVYALNIIWGYS
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
FNFQQELQTACMLMFFASIGLSADFSRLKAGGSPLLIFTIVVSVFIILQDVVGVTMASVL
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLDPLLGLVTGSIALTGGHGTAGAWGITLEEQYGVVGATTLGIAAATYGLVAGGVIGGPV
HHHHHHHHHHCCEEEECCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHCCCCCHHH
ARRLINRLGVKPGEVNPNPTPTEKLAGEQSLYSTKHNEEEAYRNKEIFEKPDNIRLITAS
HHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHCCCCHHHHHHCHHHHCCCCCEEEEEEC
STIESLALFAASLAFADIMTNLGQGTWFELPTFVWALAGGVILRNVLTMVFDFHMFDRAI
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVIGNASLSLFLAMALLSLKLWQLTDLAGPVLIILVVQTLVMIGYAYLVTFRIMGKDYDS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AVLAAGHCGFGMGATPTAIANMQAVTDRYQPSHKAFLIVPMVGAFFVDIVNATVLQIFTK
HHEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
LPFM
CCCC
>Mature Secondary Structure
MEVTLNGYYTLILATLVLLLGRFLVKRVKFLEDFNIPEPVAGGLVAAAIVYALNIIWGYS
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
FNFQQELQTACMLMFFASIGLSADFSRLKAGGSPLLIFTIVVSVFIILQDVVGVTMASVL
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLDPLLGLVTGSIALTGGHGTAGAWGITLEEQYGVVGATTLGIAAATYGLVAGGVIGGPV
HHHHHHHHHHCCEEEECCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHCCCCCHHH
ARRLINRLGVKPGEVNPNPTPTEKLAGEQSLYSTKHNEEEAYRNKEIFEKPDNIRLITAS
HHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHCCCCHHHHHHCHHHHCCCCCEEEEEEC
STIESLALFAASLAFADIMTNLGQGTWFELPTFVWALAGGVILRNVLTMVFDFHMFDRAI
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVIGNASLSLFLAMALLSLKLWQLTDLAGPVLIILVVQTLVMIGYAYLVTFRIMGKDYDS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AVLAAGHCGFGMGATPTAIANMQAVTDRYQPSHKAFLIVPMVGAFFVDIVNATVLQIFTK
HHEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
LPFM
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]