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The map label for this gene is atoB [H]

Identifier: 148653808

GI number: 148653808

Start: 2503482

End: 2504663

Strand: Direct

Name: atoB [H]

Synonym: PsycPRwf_2011

Alternate gene names: 148653808

Gene position: 2503482-2504663 (Clockwise)

Preceding gene: 148653807

Following gene: 148653809

Centisome position: 84.04

GC content: 50.08

Gene sequence:

>1182_bases
ATGTCATCAGATTCAATCGTTATTGTTAGTGGCGCCCGTACCCCAATGGGTGGTTTCCAAGGCGACCTTACTGGCGCAAC
TTCTCCGCAGTTAGGTGCAGCTGCTATTAAAGCTGCTGTAGAGCGCTCGGGTGTAAAGGCTGAAGAAATCGACGAAGTTA
TCATGGGCTGTATCTTAACCGCAGGCGTAGGCCAAGGCCCTGCTCGCCAAGCCATGCGTAATGCAGGTATCCCTGATAGC
ACTGGCGCTGTGACCATTAACAAGCTATGCGGTTCAGGTCTAAAAGCAGTGATGCAGGCGCATGATGCTATTAAAGCAGG
CAGTGCTGAGATTATCGTGGCAGGCGGCATGGAATCTATGACCAATGCGCCTTATATTCTGCCAGGTGCACGTGACGGCT
ACCGCATGGGTCACAAAGAAGTCAAAGACCATATGTTCTTAGATGGCCTAGAAGATGCCGATACCGGTAAATTGATGGGT
CAATTTGCTCAAGAGATGGCCGATGAAAAAGGCTATACTCGTGAGCAAATGGATGACTTCGCTATTGAGTCATTAAACCG
TGCGCTGACAGCCATCAAAGAAGGTCACTTTAAAGATGAAATCACGCCTGTTACTGTAAAAACGCGTAAAGGCGAAGTGG
TTATCGAGACCGATGAGCAGCCTGCTAAAGCCAATGCTGAGCGCATCCCTACCCTACGTCCAGCCTTCGCAAAAGAGGGG
ACCATCACCGCCGCTAATGCCAGCTCAATCTCTGATGGTGCTGCTGCGGTTGTGGTGACCTCTGAACAAGTAGCCCAGGA
CAAAGGCTTAAATATTGAAGCGCGTATCATCTCTACCGCTACCAACTCGCTGCACCCTAGCAAATTCACCATTGCCCCTA
TTGGTGCAATCGAAAAAGTGCTACAAAAAGCAGGTTGGTCAGTAGAAGATGTGGATCTGTGGGAGATCAATGAAGCCTTT
GCTATGGTGACCATGGCGGCAATGGATGAGCTAAATATTCCTCATGCCAAAGTCAACGTTGAAGGCGGTGCATGTGCCCT
AGGTCATCCAGTGGGCTGTTCGGGTGCCCGTATCTTGGTTACTCTAATCAACTCATTGAAGCGCACCGGCGGCAAAAAAG
GCGTGGCCTCATTATGTATCGGTGGCGGTGAAGCCGTTGCTGTCGCCATTGAAATTGCTTAG

Upstream 100 bases:

>100_bases
TTAGACTAAGACATTAACAGAAGCAAATTAAGTGATCGATTTGGCCAAGCTATCAAGTCGCTTGGCTCTTAAATAAATAA
TATTAATTAAGGATAATACT

Downstream 100 bases:

>100_bases
AGCAATTCGGTCAAGTTAGGCCAGAATCTATTTATAAAAATTCTTAAACAGAGCCTCCAAATTTGGAGGCTCTTTTTTTT
ATCACACCGTAGCAACATTT

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSSDSIVIVSGARTPMGGFQGDLTGATSPQLGAAAIKAAVERSGVKAEEIDEVIMGCILTAGVGQGPARQAMRNAGIPDS
TGAVTINKLCGSGLKAVMQAHDAIKAGSAEIIVAGGMESMTNAPYILPGARDGYRMGHKEVKDHMFLDGLEDADTGKLMG
QFAQEMADEKGYTREQMDDFAIESLNRALTAIKEGHFKDEITPVTVKTRKGEVVIETDEQPAKANAERIPTLRPAFAKEG
TITAANASSISDGAAAVVVTSEQVAQDKGLNIEARIISTATNSLHPSKFTIAPIGAIEKVLQKAGWSVEDVDLWEINEAF
AMVTMAAMDELNIPHAKVNVEGGACALGHPVGCSGARILVTLINSLKRTGGKKGVASLCIGGGEAVAVAIEIA

Sequences:

>Translated_393_residues
MSSDSIVIVSGARTPMGGFQGDLTGATSPQLGAAAIKAAVERSGVKAEEIDEVIMGCILTAGVGQGPARQAMRNAGIPDS
TGAVTINKLCGSGLKAVMQAHDAIKAGSAEIIVAGGMESMTNAPYILPGARDGYRMGHKEVKDHMFLDGLEDADTGKLMG
QFAQEMADEKGYTREQMDDFAIESLNRALTAIKEGHFKDEITPVTVKTRKGEVVIETDEQPAKANAERIPTLRPAFAKEG
TITAANASSISDGAAAVVVTSEQVAQDKGLNIEARIISTATNSLHPSKFTIAPIGAIEKVLQKAGWSVEDVDLWEINEAF
AMVTMAAMDELNIPHAKVNVEGGACALGHPVGCSGARILVTLINSLKRTGGKKGVASLCIGGGEAVAVAIEIA
>Mature_392_residues
SSDSIVIVSGARTPMGGFQGDLTGATSPQLGAAAIKAAVERSGVKAEEIDEVIMGCILTAGVGQGPARQAMRNAGIPDST
GAVTINKLCGSGLKAVMQAHDAIKAGSAEIIVAGGMESMTNAPYILPGARDGYRMGHKEVKDHMFLDGLEDADTGKLMGQ
FAQEMADEKGYTREQMDDFAIESLNRALTAIKEGHFKDEITPVTVKTRKGEVVIETDEQPAKANAERIPTLRPAFAKEGT
ITAANASSISDGAAAVVVTSEQVAQDKGLNIEARIISTATNSLHPSKFTIAPIGAIEKVLQKAGWSVEDVDLWEINEAFA
MVTMAAMDELNIPHAKVNVEGGACALGHPVGCSGARILVTLINSLKRTGGKKGVASLCIGGGEAVAVAIEIA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=392, Percent_Identity=47.7040816326531, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI4557237, Length=388, Percent_Identity=42.0103092783505, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI167614485, Length=389, Percent_Identity=38.8174807197943, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI4501853, Length=403, Percent_Identity=36.4764267990074, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI4504327, Length=425, Percent_Identity=29.1764705882353, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI194353979, Length=162, Percent_Identity=40.1234567901235, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI87082165, Length=387, Percent_Identity=45.4780361757106, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1788554, Length=387, Percent_Identity=49.0956072351421, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1787663, Length=395, Percent_Identity=37.9746835443038, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI48994986, Length=400, Percent_Identity=36, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1788683, Length=409, Percent_Identity=28.6063569682152, Blast_Score=149, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17535921, Length=393, Percent_Identity=44.2748091603053, Blast_Score=311, Evalue=5e-85,
Organism=Caenorhabditis elegans, GI25147385, Length=391, Percent_Identity=40.4092071611253, Blast_Score=301, Evalue=5e-82,
Organism=Caenorhabditis elegans, GI133906874, Length=392, Percent_Identity=39.7959183673469, Blast_Score=287, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI17535917, Length=395, Percent_Identity=32.1518987341772, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17551802, Length=425, Percent_Identity=30.3529411764706, Blast_Score=172, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6325229, Length=397, Percent_Identity=45.8438287153652, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6322031, Length=387, Percent_Identity=35.9173126614987, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24655093, Length=387, Percent_Identity=47.0284237726098, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24640423, Length=388, Percent_Identity=45.6185567010309, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI17648125, Length=393, Percent_Identity=37.9134860050891, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI17137578, Length=425, Percent_Identity=28.9411764705882, Blast_Score=167, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40781; Mature: 40650

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00098 THIOLASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDSIVIVSGARTPMGGFQGDLTGATSPQLGAAAIKAAVERSGVKAEEIDEVIMGCILT
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AGVGQGPARQAMRNAGIPDSTGAVTINKLCGSGLKAVMQAHDAIKAGSAEIIVAGGMESM
CCCCCCHHHHHHHHCCCCCCCCCEEHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCHHHH
TNAPYILPGARDGYRMGHKEVKDHMFLDGLEDADTGKLMGQFAQEMADEKGYTREQMDDF
CCCCEEECCCCCCHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
AIESLNRALTAIKEGHFKDEITPVTVKTRKGEVVIETDEQPAKANAERIPTLRPAFAKEG
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCHHHCCCCCCCCCCCC
TITAANASSISDGAAAVVVTSEQVAQDKGLNIEARIISTATNSLHPSKFTIAPIGAIEKV
CEEECCCCCCCCCCEEEEEECHHHHHCCCCCEEEEEEEECCCCCCCCCEEEECHHHHHHH
LQKAGWSVEDVDLWEINEAFAMVTMAAMDELNIPHAKVNVEGGACALGHPVGCSGARILV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCCCHHHHH
TLINSLKRTGGKKGVASLCIGGGEAVAVAIEIA
HHHHHHHHCCCCCCCHHEEECCCCEEEEEEEEC
>Mature Secondary Structure 
SSDSIVIVSGARTPMGGFQGDLTGATSPQLGAAAIKAAVERSGVKAEEIDEVIMGCILT
CCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AGVGQGPARQAMRNAGIPDSTGAVTINKLCGSGLKAVMQAHDAIKAGSAEIIVAGGMESM
CCCCCCHHHHHHHHCCCCCCCCCEEHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCHHHH
TNAPYILPGARDGYRMGHKEVKDHMFLDGLEDADTGKLMGQFAQEMADEKGYTREQMDDF
CCCCEEECCCCCCHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
AIESLNRALTAIKEGHFKDEITPVTVKTRKGEVVIETDEQPAKANAERIPTLRPAFAKEG
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCHHHCCCCCCCCCCCC
TITAANASSISDGAAAVVVTSEQVAQDKGLNIEARIISTATNSLHPSKFTIAPIGAIEKV
CEEECCCCCCCCCCEEEEEECHHHHHCCCCCEEEEEEEECCCCCCCCCEEEECHHHHHHH
LQKAGWSVEDVDLWEINEAFAMVTMAAMDELNIPHAKVNVEGGACALGHPVGCSGARILV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCCCHHHHH
TLINSLKRTGGKKGVASLCIGGGEAVAVAIEIA
HHHHHHHHCCCCCCCHHEEECCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]