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The map label for this gene is nadA [H]

Identifier: 148653761

GI number: 148653761

Start: 2446999

End: 2448186

Strand: Direct

Name: nadA [H]

Synonym: PsycPRwf_1964

Alternate gene names: 148653761

Gene position: 2446999-2448186 (Clockwise)

Preceding gene: 148653757

Following gene: 148653762

Centisome position: 82.14

GC content: 49.24

Gene sequence:

>1188_bases
ATGACTACCTCACAAGCCAGCTCGTACACGCCCGCTGAGAAGACTGAGATTTTTGCTTATGACGCGCCAACTTTGGCCCA
AAGCAACCAGTCTTCTGCCATTCAAAGCATTGATATCGACTATGCCAAAGCTAAGATACCCGCTGAGCTGTCTCGTACTG
AGCGCCTGCAAGTGGTAGAAAACATTAAGCGCCTGCTAAAACAGCACAATGCGGTACTGGTGGCGCATTATTATGTCGAC
CCCTACATTCAGGACTTAGCCTTAGAGACCGGCGGCTGTGTGGGAGACTCCTTAGAGATGGCGCGTTTTGGTAAAGAACA
TGAGGCGCAAACCTTGGTGGTGGCCGGCGTAAGGTTTATGGGGGAGTCTGCCAAAATTCTGAGTATGGAAAAAACCGTAC
TTATGGCAGATCTTGAAGCTGAGTGTTCGCTGGATTTGGGCTGCCCTATAGACGAGTTTAGTGCATTTTGTGATCAGCAT
CCCGACCGCACTGTGGTGGTCTATGCCAACACCAGCGCAGAAGTCAAAGCACGTGCAGATTGGGTGGTGACCTCATCTGT
AGGTCTTGAGATTGTGACTCATCTGCATGAACAGGGTCGAAAAATAATCTGGGGACCAGACCGTCATTTGGGTAAATACA
TTCAAAAACAGACCGGTGCTGACATGCTGCTGTGGCAAGGCTCGTGTATTGTACATAACGAATTTAAAGCACGTGAACTT
GAGCAATTAAAAGCACAATACCCTGAGGCTGTGGTGCTGGTTCATCCGGAGTCTCCTGATAGCGTGGTGGCTTTGGCCGA
TGTGGTGGGCTCAACCAGCAAGCTATTAAACGCCACCAAAGAGATGGATAACCAAACCTTTATCGTGGGCACTGACCTTG
GCATCTTACATGAGATGCAAAAGCACTCACCAGATAAGCTGTTTTTGGCAGCCCCTACTGCTGGTGAAAGCGCAACTTGT
AAGAGCTGTGCGTTTTGCCCTTGGATGGCCATGAATGGTCTAAAAGGTATCGAAAACTGTCTACAGACTGGCAGTGGCGA
GATTAAATTAGCGCCCGAATTGGCACAGGCGGCTTTAAAGCCACTACAGCGTATGTTGGATTTCGCCGCTGAGCAAAAAC
GTCGTGTGGCCACCAGTGGCGATATTATTGAAGACCGTGCGTTATTTGCAAACGTTGGCCCAGCTTAA

Upstream 100 bases:

>100_bases
CTCAAAATGAGCATAATTATAGCCATCGCTTTATTATTTGCTTATCAAGTTTTGATTAATTAAGTGCCGCCTTTAGAGCA
CACAATGACAGGGATTTTTT

Downstream 100 bases:

>100_bases
GTTTTCGCTATATTAAGCTGCTGCTGGCAGGCTAAATGTAGTCCCCATAACACCTTTTAACCAGAGAGCACCCTATGCCA
ACTTATTCAGTGGATAACGC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTTSQASSYTPAEKTEIFAYDAPTLAQSNQSSAIQSIDIDYAKAKIPAELSRTERLQVVENIKRLLKQHNAVLVAHYYVD
PYIQDLALETGGCVGDSLEMARFGKEHEAQTLVVAGVRFMGESAKILSMEKTVLMADLEAECSLDLGCPIDEFSAFCDQH
PDRTVVVYANTSAEVKARADWVVTSSVGLEIVTHLHEQGRKIIWGPDRHLGKYIQKQTGADMLLWQGSCIVHNEFKAREL
EQLKAQYPEAVVLVHPESPDSVVALADVVGSTSKLLNATKEMDNQTFIVGTDLGILHEMQKHSPDKLFLAAPTAGESATC
KSCAFCPWMAMNGLKGIENCLQTGSGEIKLAPELAQAALKPLQRMLDFAAEQKRRVATSGDIIEDRALFANVGPA

Sequences:

>Translated_395_residues
MTTSQASSYTPAEKTEIFAYDAPTLAQSNQSSAIQSIDIDYAKAKIPAELSRTERLQVVENIKRLLKQHNAVLVAHYYVD
PYIQDLALETGGCVGDSLEMARFGKEHEAQTLVVAGVRFMGESAKILSMEKTVLMADLEAECSLDLGCPIDEFSAFCDQH
PDRTVVVYANTSAEVKARADWVVTSSVGLEIVTHLHEQGRKIIWGPDRHLGKYIQKQTGADMLLWQGSCIVHNEFKAREL
EQLKAQYPEAVVLVHPESPDSVVALADVVGSTSKLLNATKEMDNQTFIVGTDLGILHEMQKHSPDKLFLAAPTAGESATC
KSCAFCPWMAMNGLKGIENCLQTGSGEIKLAPELAQAALKPLQRMLDFAAEQKRRVATSGDIIEDRALFANVGPA
>Mature_394_residues
TTSQASSYTPAEKTEIFAYDAPTLAQSNQSSAIQSIDIDYAKAKIPAELSRTERLQVVENIKRLLKQHNAVLVAHYYVDP
YIQDLALETGGCVGDSLEMARFGKEHEAQTLVVAGVRFMGESAKILSMEKTVLMADLEAECSLDLGCPIDEFSAFCDQHP
DRTVVVYANTSAEVKARADWVVTSSVGLEIVTHLHEQGRKIIWGPDRHLGKYIQKQTGADMLLWQGSCIVHNEFKARELE
QLKAQYPEAVVLVHPESPDSVVALADVVGSTSKLLNATKEMDNQTFIVGTDLGILHEMQKHSPDKLFLAAPTAGESATCK
SCAFCPWMAMNGLKGIENCLQTGSGEIKLAPELAQAALKPLQRMLDFAAEQKRRVATSGDIIEDRALFANVGPA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=326, Percent_Identity=64.7239263803681, Blast_Score=445, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 43165; Mature: 43033

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSQASSYTPAEKTEIFAYDAPTLAQSNQSSAIQSIDIDYAKAKIPAELSRTERLQVVE
CCCCCCCCCCCCCCCEEEEECCCCHHCCCCCHHHHEECCCHHHHCCCHHHHHHHHHHHHH
NIKRLLKQHNAVLVAHYYVDPYIQDLALETGGCVGDSLEMARFGKEHEAQTLVVAGVRFM
HHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEEHHHHC
GESAKILSMEKTVLMADLEAECSLDLGCPIDEFSAFCDQHPDRTVVVYANTSAEVKARAD
CCCCCEEEHHHEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEECC
WVVTSSVGLEIVTHLHEQGRKIIWGPDRHLGKYIQKQTGADMLLWQGSCIVHNEFKAREL
EEEECHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHH
EQLKAQYPEAVVLVHPESPDSVVALADVVGSTSKLLNATKEMDNQTFIVGTDLGILHEMQ
HHHHHHCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCHHHHHHHH
KHSPDKLFLAAPTAGESATCKSCAFCPWMAMNGLKGIENCLQTGSGEIKLAPELAQAALK
HCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHH
PLQRMLDFAAEQKRRVATSGDIIEDRALFANVGPA
HHHHHHHHHHHHHHHCCCCCCEECCCHHCCCCCCC
>Mature Secondary Structure 
TTSQASSYTPAEKTEIFAYDAPTLAQSNQSSAIQSIDIDYAKAKIPAELSRTERLQVVE
CCCCCCCCCCCCCCEEEEECCCCHHCCCCCHHHHEECCCHHHHCCCHHHHHHHHHHHHH
NIKRLLKQHNAVLVAHYYVDPYIQDLALETGGCVGDSLEMARFGKEHEAQTLVVAGVRFM
HHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEEHHHHC
GESAKILSMEKTVLMADLEAECSLDLGCPIDEFSAFCDQHPDRTVVVYANTSAEVKARAD
CCCCCEEEHHHEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEECC
WVVTSSVGLEIVTHLHEQGRKIIWGPDRHLGKYIQKQTGADMLLWQGSCIVHNEFKAREL
EEEECHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHH
EQLKAQYPEAVVLVHPESPDSVVALADVVGSTSKLLNATKEMDNQTFIVGTDLGILHEMQ
HHHHHHCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCHHHHHHHH
KHSPDKLFLAAPTAGESATCKSCAFCPWMAMNGLKGIENCLQTGSGEIKLAPELAQAALK
HCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHH
PLQRMLDFAAEQKRRVATSGDIIEDRALFANVGPA
HHHHHHHHHHHHHHHCCCCCCEECCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA