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The map label for this gene is nadB1 [H]

Identifier: 148653762

GI number: 148653762

Start: 2448297

End: 2450168

Strand: Direct

Name: nadB1 [H]

Synonym: PsycPRwf_1965

Alternate gene names: 148653762

Gene position: 2448297-2450168 (Clockwise)

Preceding gene: 148653761

Following gene: 148653763

Centisome position: 82.19

GC content: 52.72

Gene sequence:

>1872_bases
ATGGCCAGTGCTGCCCCTCATCAAAACTGTGATGTGTTGATTATCGGCGCGGGGTTGGCAGGGCTTTCGGCAGCGCTTTC
GTTGCCAAAACACCTCAGCATCGCTGTGCTTGCCAAGCAAGATCTTCAGGCCTGCTCAAGCCACTACGCTCAAGGCGGTA
TTGCCGCAGTGATTGATAGCGAGGACAGCGTCGCCGATCATGTCAGCGACACGTTAATCGCCGGCGATGGCTTGTGTGAT
GCGGCGGCCACCACCCAAATCCTCGCCCAAGGTGCCAACGCCATTGATTGGCTGCTCAAACATAAGGTACCTTTTACCAC
CAAGCACCCTCAGTCAGATGCTGACTTAAAGCCCACCGCTACGCTCGCTGACCTACATCTGACTCAAGAAGGCGGTCATG
GCTGTCGACGTGTGGCACATGCTGATGATGCCACTGGCAAGCACATTATGCAGGCACTACAACAGCAAATCGCCGCGGCA
CCTAATATCAAGCTCTACACCTATCATGAGGCGCTTAGCCTATTGACTGACAATCATCGCTGCACAGGCGCTATCGTGGT
GGACACACAGACCCAGAAGCTGGTTCAATTTGATAGCCAAGCGGTGGTACTTGCCAGCGGCGGGCTGGGTCAATTATTCA
CCCGAGCCACAGCGCCCAATGTCTGCATGGGCGATGGTATTATGATGGCGTGGGAAGCAGGCTGCCGTTTGGCTAACTTA
GAGTTTATCCAGTTTCATCCAACCGGTCTGGTTTATAATGATGCGCAAGGCAGCAGCAATTTTCTGATCTCTGAAGCCGT
GCGCGGTGAAGGCGGCCTACTTCGCTGTCCCATTAGCCATGAGCGCTTTATGCCACGCTATGATAAGCGCGAAGAATTAG
CCCCCCGTGACATTGTCGCTCGTGCTATTGCTAATGAGATTGCTCATAACGGCTTAGGCTACGTTCATTTGGACATCTCG
CATAAACCCGCTGCGTTTATTCGTGAGCACTTCCCCGATATCTACGCCCACTGCTTAAGCTTAGGCATCGACATTACCAC
AGACCCTATTCCGGTAGCGCCAACGGCTCATTATGCCTGTGGCGGCGTACTGTCGACGGCGAAGGGGCAGACCGATATCA
AAGGCTTATATGCTGCCGGTGAAGTCGCCAATACTGGATTACATGGCGCCAATCGTCTGGCCAGTAACTCCTTACTTGAA
TGCGTGGTAATGGGCCGTGCAATTGCCCATCATTTACCCAGTTACTTGCTGGATAAAGACAATTGGCAAGCGCCGCAGTC
TCTTCATAAGCCATTGGTTATTGAGCCTAGCCTCGATGCGCCTGTTTCACCGTTAGCCTTCAATACCACCAATAACGACA
CCGATCAGCCGCCGCTTAGTTTAACCGCTCTTAAGCAGTTAATGAGCGAGCACATGGGCATCAGACGCAGCGCCTCAGGT
CTAAATATGGCCTTAAAGCAACTGTCTTTTTGGCAACAACAGCTGTCAGCGCCCATCCCAAGTAAAGCAGATGTGGACAG
TCAAGATATAGTGGCTCTGCTTAATAGCAGACGCTTACAGCGCCTACTTCAGCTGGCAAGCTTACTATTCGGCTGTGCCC
TTAACCGCCTTGAAAGCCGAGGTGGTCATTACCGCAATGACTACCCAAGCCTTGCCGACATAGCCGCCATGAGCTTAGTA
CAAGGCTTGCAGCCACCGCAGCTGGACTGTAACGCTTTATGTTTATGCAATGGCACCGACAGCTTTGGACAGCTAACCCC
GCTTTACGCTCAAAACATAGCGGGGCAAGCAGCAGAGCAAAATTCAGTGCGGCCTAAAGCAATGCCCCTGTTAGCCGACC
GATGCACAGCTTTTATTCCCAAAGCCGTCTAG

Upstream 100 bases:

>100_bases
TATTAAGCTGCTGCTGGCAGGCTAAATGTAGTCCCCATAACACCTTTTAACCAGAGAGCACCCTATGCCAACTTATTCAG
TGGATAACGCATTAGCACAG

Downstream 100 bases:

>100_bases
CTAAAAAAAAGCCGTCTAGCTAAAAGCTAATAAAGTTGCCCCGTTGATTTAGCGGGGTATTTTTGTTGACACCACTAAAC
CAAATAACACTGAGCGAGTA

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO 1; Quinolinate synthase B 1 [H]

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MASAAPHQNCDVLIIGAGLAGLSAALSLPKHLSIAVLAKQDLQACSSHYAQGGIAAVIDSEDSVADHVSDTLIAGDGLCD
AAATTQILAQGANAIDWLLKHKVPFTTKHPQSDADLKPTATLADLHLTQEGGHGCRRVAHADDATGKHIMQALQQQIAAA
PNIKLYTYHEALSLLTDNHRCTGAIVVDTQTQKLVQFDSQAVVLASGGLGQLFTRATAPNVCMGDGIMMAWEAGCRLANL
EFIQFHPTGLVYNDAQGSSNFLISEAVRGEGGLLRCPISHERFMPRYDKREELAPRDIVARAIANEIAHNGLGYVHLDIS
HKPAAFIREHFPDIYAHCLSLGIDITTDPIPVAPTAHYACGGVLSTAKGQTDIKGLYAAGEVANTGLHGANRLASNSLLE
CVVMGRAIAHHLPSYLLDKDNWQAPQSLHKPLVIEPSLDAPVSPLAFNTTNNDTDQPPLSLTALKQLMSEHMGIRRSASG
LNMALKQLSFWQQQLSAPIPSKADVDSQDIVALLNSRRLQRLLQLASLLFGCALNRLESRGGHYRNDYPSLADIAAMSLV
QGLQPPQLDCNALCLCNGTDSFGQLTPLYAQNIAGQAAEQNSVRPKAMPLLADRCTAFIPKAV

Sequences:

>Translated_623_residues
MASAAPHQNCDVLIIGAGLAGLSAALSLPKHLSIAVLAKQDLQACSSHYAQGGIAAVIDSEDSVADHVSDTLIAGDGLCD
AAATTQILAQGANAIDWLLKHKVPFTTKHPQSDADLKPTATLADLHLTQEGGHGCRRVAHADDATGKHIMQALQQQIAAA
PNIKLYTYHEALSLLTDNHRCTGAIVVDTQTQKLVQFDSQAVVLASGGLGQLFTRATAPNVCMGDGIMMAWEAGCRLANL
EFIQFHPTGLVYNDAQGSSNFLISEAVRGEGGLLRCPISHERFMPRYDKREELAPRDIVARAIANEIAHNGLGYVHLDIS
HKPAAFIREHFPDIYAHCLSLGIDITTDPIPVAPTAHYACGGVLSTAKGQTDIKGLYAAGEVANTGLHGANRLASNSLLE
CVVMGRAIAHHLPSYLLDKDNWQAPQSLHKPLVIEPSLDAPVSPLAFNTTNNDTDQPPLSLTALKQLMSEHMGIRRSASG
LNMALKQLSFWQQQLSAPIPSKADVDSQDIVALLNSRRLQRLLQLASLLFGCALNRLESRGGHYRNDYPSLADIAAMSLV
QGLQPPQLDCNALCLCNGTDSFGQLTPLYAQNIAGQAAEQNSVRPKAMPLLADRCTAFIPKAV
>Mature_622_residues
ASAAPHQNCDVLIIGAGLAGLSAALSLPKHLSIAVLAKQDLQACSSHYAQGGIAAVIDSEDSVADHVSDTLIAGDGLCDA
AATTQILAQGANAIDWLLKHKVPFTTKHPQSDADLKPTATLADLHLTQEGGHGCRRVAHADDATGKHIMQALQQQIAAAP
NIKLYTYHEALSLLTDNHRCTGAIVVDTQTQKLVQFDSQAVVLASGGLGQLFTRATAPNVCMGDGIMMAWEAGCRLANLE
FIQFHPTGLVYNDAQGSSNFLISEAVRGEGGLLRCPISHERFMPRYDKREELAPRDIVARAIANEIAHNGLGYVHLDISH
KPAAFIREHFPDIYAHCLSLGIDITTDPIPVAPTAHYACGGVLSTAKGQTDIKGLYAAGEVANTGLHGANRLASNSLLEC
VVMGRAIAHHLPSYLLDKDNWQAPQSLHKPLVIEPSLDAPVSPLAFNTTNNDTDQPPLSLTALKQLMSEHMGIRRSASGL
NMALKQLSFWQQQLSAPIPSKADVDSQDIVALLNSRRLQRLLQLASLLFGCALNRLESRGGHYRNDYPSLADIAAMSLVQ
GLQPPQLDCNALCLCNGTDSFGQLTPLYAQNIAGQAAEQNSVRPKAMPLLADRCTAFIPKAV

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=542, Percent_Identity=31.7343173431734, Blast_Score=186, Evalue=7e-47,
Organism=Escherichia coli, GI1788928, Length=555, Percent_Identity=41.8018018018018, Blast_Score=410, Evalue=1e-115,
Organism=Escherichia coli, GI1790597, Length=537, Percent_Identity=30.5400372439479, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1786942, Length=545, Percent_Identity=29.7247706422018, Blast_Score=172, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17550100, Length=545, Percent_Identity=31.9266055045872, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17505833, Length=530, Percent_Identity=31.3207547169811, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI71986328, Length=413, Percent_Identity=26.634382566586, Blast_Score=95, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322701, Length=531, Percent_Identity=32.015065913371, Blast_Score=219, Evalue=9e-58,
Organism=Saccharomyces cerevisiae, GI6322416, Length=526, Percent_Identity=31.1787072243346, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6322511, Length=481, Percent_Identity=27.4428274428274, Blast_Score=117, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6320788, Length=321, Percent_Identity=29.595015576324, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17137288, Length=527, Percent_Identity=31.8785578747628, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24655642, Length=527, Percent_Identity=31.8785578747628, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24655647, Length=527, Percent_Identity=31.8785578747628, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24663005, Length=532, Percent_Identity=30.0751879699248, Blast_Score=194, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 66576; Mature: 66444

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAAPHQNCDVLIIGAGLAGLSAALSLPKHLSIAVLAKQDLQACSSHYAQGGIAAVIDS
CCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEECC
EDSVADHVSDTLIAGDGLCDAAATTQILAQGANAIDWLLKHKVPFTTKHPQSDADLKPTA
CCHHHHHHHHHEEECCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
TLADLHLTQEGGHGCRRVAHADDATGKHIMQALQQQIAAAPNIKLYTYHEALSLLTDNHR
EEEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCC
CTGAIVVDTQTQKLVQFDSQAVVLASGGLGQLFTRATAPNVCMGDGIMMAWEAGCRLANL
EEEEEEEECCHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCEECCCEEEEECCCCEEECE
EFIQFHPTGLVYNDAQGSSNFLISEAVRGEGGLLRCPISHERFMPRYDKREELAPRDIVA
EEEEECCCEEEEECCCCCCCEEEEHHHCCCCCEEECCCCHHHCCCCCCCHHHCCHHHHHH
RAIANEIAHNGLGYVHLDISHKPAAFIREHFPDIYAHCLSLGIDITTDPIPVAPTAHYAC
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
GGVLSTAKGQTDIKGLYAAGEVANTGLHGANRLASNSLLECVVMGRAIAHHLPSYLLDKD
CCHHHCCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NWQAPQSLHKPLVIEPSLDAPVSPLAFNTTNNDTDQPPLSLTALKQLMSEHMGIRRSASG
CCCCCHHHCCCEEECCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCH
LNMALKQLSFWQQQLSAPIPSKADVDSQDIVALLNSRRLQRLLQLASLLFGCALNRLESR
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGHYRNDYPSLADIAAMSLVQGLQPPQLDCNALCLCNGTDSFGQLTPLYAQNIAGQAAEQ
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCHHHC
NSVRPKAMPLLADRCTAFIPKAV
CCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASAAPHQNCDVLIIGAGLAGLSAALSLPKHLSIAVLAKQDLQACSSHYAQGGIAAVIDS
CCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEECC
EDSVADHVSDTLIAGDGLCDAAATTQILAQGANAIDWLLKHKVPFTTKHPQSDADLKPTA
CCHHHHHHHHHEEECCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
TLADLHLTQEGGHGCRRVAHADDATGKHIMQALQQQIAAAPNIKLYTYHEALSLLTDNHR
EEEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCC
CTGAIVVDTQTQKLVQFDSQAVVLASGGLGQLFTRATAPNVCMGDGIMMAWEAGCRLANL
EEEEEEEECCHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCEECCCEEEEECCCCEEECE
EFIQFHPTGLVYNDAQGSSNFLISEAVRGEGGLLRCPISHERFMPRYDKREELAPRDIVA
EEEEECCCEEEEECCCCCCCEEEEHHHCCCCCEEECCCCHHHCCCCCCCHHHCCHHHHHH
RAIANEIAHNGLGYVHLDISHKPAAFIREHFPDIYAHCLSLGIDITTDPIPVAPTAHYAC
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
GGVLSTAKGQTDIKGLYAAGEVANTGLHGANRLASNSLLECVVMGRAIAHHLPSYLLDKD
CCHHHCCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NWQAPQSLHKPLVIEPSLDAPVSPLAFNTTNNDTDQPPLSLTALKQLMSEHMGIRRSASG
CCCCCHHHCCCEEECCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCH
LNMALKQLSFWQQQLSAPIPSKADVDSQDIVALLNSRRLQRLLQLASLLFGCALNRLESR
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGHYRNDYPSLADIAAMSLVQGLQPPQLDCNALCLCNGTDSFGQLTPLYAQNIAGQAAEQ
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCHHHC
NSVRPKAMPLLADRCTAFIPKAV
CCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]