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The map label for this gene is asd [H]

Identifier: 148653588

GI number: 148653588

Start: 2221096

End: 2222238

Strand: Direct

Name: asd [H]

Synonym: PsycPRwf_1791

Alternate gene names: 148653588

Gene position: 2221096-2222238 (Clockwise)

Preceding gene: 148653586

Following gene: 148653601

Centisome position: 74.56

GC content: 49.52

Gene sequence:

>1143_bases
ATGAGTCAATTAAAAGTAGGTCTTGTTGGATGGCGTGGCATGGTAGGTTCTGTGCTTATGCAGCGTATGGTAGAGGAAAA
TGATTTTGCAAATATCACCCCCATTTTCTTTTCGACCAGTAACGCCGGTGGTGATGCACCAAGCTTTGAGGGCGTCACGC
ACACCGAAGACAGTGCTACACTAAAAGATGCTCATGATATCGAAGCGCTCAGCAGCTGTGACGTGATTATCACTTGTCAA
GGCGGCGACTACACAAAAGCGGTACATGGCCCACTGCGTGATTCAGGTTGGCAAGGTTACTGGGTCGATGCCGCCAGCAG
CCTACGCATGGAGCAAGATAGCGTCATTATCCTAGATCCGGTTAACCGCTCAGTTATCGATGAGGCGCTACAACAAGGTA
CCAAAGACTTTATCGGTGGTAACTGTACAGTATCACTGATGCTGATGGCCATTGGCGAGTTATTCAACCGTGGCTGGGTG
GAGTGGGTATCAGCCATGACCTACCAAGCCGCCAGTGGCTCAGGTGCCAACAACATGCGCGAGCTCATCAGTGGCATGGG
ATTATTACGCGACTCAGTCGCTGACGAGTTGGCCAATCCTGCCAGCGCCATCTTGGCCATTGATAAAAAAATTGCCGAAA
CTCAGCGCAGCGACAGCTTCCCTACCCAGTACTTTGGGGTTCCACTCGCCGGCAGCTTAATTCCTTATATTGACAGCCAG
CTTGAAAACAAGCAATCTCGTGAAGAATGGAAAGGCGGCGTTGAAACCAACAAAATTCTAAACAACCAAGGTGCGGATAT
TATCCCAATCGATGGTCTATGCGTTCGTGTTGGCTCAATGCGTTGCCATGCTCAAGGCTTAACCATTAAGCTAAAACAAG
ATATCCCACTAGAGGAAATTGAAGCGGCATTAAAGAACAGCGGTAATCAATGGTTAGACTTCGTAGAAGATGACAAAGAG
CAGACCATGCAGCGTCTGACGCCTGTCGCCGTTACCGGTACCTTAACCGTGGCACTTGGCCGTCTACGTAAGCTTAATAT
GGGACCTGAGTACCTAGGTGCCTTCACTGTTGGTGACCAACTACTGTGGGGTGCTGCAGAGCCTTTACGCCGTATGCTTA
ACATCATTCAGCAGCAAGGCTAA

Upstream 100 bases:

>100_bases
ACTGTATTTTGTAGCCAAGCTCTGCCGCTTATTGAGCAAATCTGAGCACAGCGTTATTCATTAAATAAATCATTTTAGGC
GAATACACAAGGGGTATTTC

Downstream 100 bases:

>100_bases
GCCCTACTACATTACAGATTAGCTGGATTATTGACATTTGATCCCAAACAAAAACCCCTAGCATTGCTAGGGGTTTTTGT
TTGATTCACTGTTTAATTGT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSQLKVGLVGWRGMVGSVLMQRMVEENDFANITPIFFSTSNAGGDAPSFEGVTHTEDSATLKDAHDIEALSSCDVIITCQ
GGDYTKAVHGPLRDSGWQGYWVDAASSLRMEQDSVIILDPVNRSVIDEALQQGTKDFIGGNCTVSLMLMAIGELFNRGWV
EWVSAMTYQAASGSGANNMRELISGMGLLRDSVADELANPASAILAIDKKIAETQRSDSFPTQYFGVPLAGSLIPYIDSQ
LENKQSREEWKGGVETNKILNNQGADIIPIDGLCVRVGSMRCHAQGLTIKLKQDIPLEEIEAALKNSGNQWLDFVEDDKE
QTMQRLTPVAVTGTLTVALGRLRKLNMGPEYLGAFTVGDQLLWGAAEPLRRMLNIIQQQG

Sequences:

>Translated_380_residues
MSQLKVGLVGWRGMVGSVLMQRMVEENDFANITPIFFSTSNAGGDAPSFEGVTHTEDSATLKDAHDIEALSSCDVIITCQ
GGDYTKAVHGPLRDSGWQGYWVDAASSLRMEQDSVIILDPVNRSVIDEALQQGTKDFIGGNCTVSLMLMAIGELFNRGWV
EWVSAMTYQAASGSGANNMRELISGMGLLRDSVADELANPASAILAIDKKIAETQRSDSFPTQYFGVPLAGSLIPYIDSQ
LENKQSREEWKGGVETNKILNNQGADIIPIDGLCVRVGSMRCHAQGLTIKLKQDIPLEEIEAALKNSGNQWLDFVEDDKE
QTMQRLTPVAVTGTLTVALGRLRKLNMGPEYLGAFTVGDQLLWGAAEPLRRMLNIIQQQG
>Mature_379_residues
SQLKVGLVGWRGMVGSVLMQRMVEENDFANITPIFFSTSNAGGDAPSFEGVTHTEDSATLKDAHDIEALSSCDVIITCQG
GDYTKAVHGPLRDSGWQGYWVDAASSLRMEQDSVIILDPVNRSVIDEALQQGTKDFIGGNCTVSLMLMAIGELFNRGWVE
WVSAMTYQAASGSGANNMRELISGMGLLRDSVADELANPASAILAIDKKIAETQRSDSFPTQYFGVPLAGSLIPYIDSQL
ENKQSREEWKGGVETNKILNNQGADIIPIDGLCVRVGSMRCHAQGLTIKLKQDIPLEEIEAALKNSGNQWLDFVEDDKEQ
TMQRLTPVAVTGTLTVALGRLRKLNMGPEYLGAFTVGDQLLWGAAEPLRRMLNIIQQQG

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=368, Percent_Identity=63.8586956521739, Blast_Score=483, Evalue=1e-138,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 41359; Mature: 41228

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLKVGLVGWRGMVGSVLMQRMVEENDFANITPIFFSTSNAGGDAPSFEGVTHTEDSAT
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
LKDAHDIEALSSCDVIITCQGGDYTKAVHGPLRDSGWQGYWVDAASSLRMEQDSVIILDP
CCCHHHHHHHCCCCEEEEECCCCCCHHHCCCCCCCCCCEEEECCHHHCEECCCCEEEECC
VNRSVIDEALQQGTKDFIGGNCTVSLMLMAIGELFNRGWVEWVSAMTYQAASGSGANNMR
CCHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHH
ELISGMGLLRDSVADELANPASAILAIDKKIAETQRSDSFPTQYFGVPLAGSLIPYIDSQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCHHHHHHHHH
LENKQSREEWKGGVETNKILNNQGADIIPIDGLCVRVGSMRCHAQGLTIKLKQDIPLEEI
HHHHHHHHHHCCCCCHHHHHCCCCCCEEECCHHHHHHCCCEEEECCCEEEEECCCCHHHH
EAALKNSGNQWLDFVEDDKEQTMQRLTPVAVTGTLTVALGRLRKLNMGPEYLGAFTVGDQ
HHHHHCCCCHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCH
LLWGAAEPLRRMLNIIQQQG
HHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQLKVGLVGWRGMVGSVLMQRMVEENDFANITPIFFSTSNAGGDAPSFEGVTHTEDSAT
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
LKDAHDIEALSSCDVIITCQGGDYTKAVHGPLRDSGWQGYWVDAASSLRMEQDSVIILDP
CCCHHHHHHHCCCCEEEEECCCCCCHHHCCCCCCCCCCEEEECCHHHCEECCCCEEEECC
VNRSVIDEALQQGTKDFIGGNCTVSLMLMAIGELFNRGWVEWVSAMTYQAASGSGANNMR
CCHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHH
ELISGMGLLRDSVADELANPASAILAIDKKIAETQRSDSFPTQYFGVPLAGSLIPYIDSQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCHHHHHHHHH
LENKQSREEWKGGVETNKILNNQGADIIPIDGLCVRVGSMRCHAQGLTIKLKQDIPLEEI
HHHHHHHHHHCCCCCHHHHHCCCCCCEEECCHHHHHHCCCEEEECCCEEEEECCCCHHHH
EAALKNSGNQWLDFVEDDKEQTMQRLTPVAVTGTLTVALGRLRKLNMGPEYLGAFTVGDQ
HHHHHCCCCHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCH
LLWGAAEPLRRMLNIIQQQG
HHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9084174; 10984043 [H]