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The map label for this gene is lldD [H]

Identifier: 148653264

GI number: 148653264

Start: 1793547

End: 1794605

Strand: Direct

Name: lldD [H]

Synonym: PsycPRwf_1462

Alternate gene names: 148653264

Gene position: 1793547-1794605 (Clockwise)

Preceding gene: 148653263

Following gene: 148653265

Centisome position: 60.21

GC content: 45.61

Gene sequence:

>1059_bases
ATGACTCACCCCAGCACAGACATTAACGCCGATTATGAGATTAATGACTTGTCGCAAGTCACCAATCTTTTTGACTTTGA
AGTATTGGCAAAAAAGAAAATGAGCAAAGGCGCATTTGCCTACGTCTCAACTGGTGCCGGCGATGAAATTACGCATCAAA
ATAACCACCGTGCTTATGACCACATCACCTTAAACCCTAGAGTGTTAAATGATGCAAAAAAGCTAGATACTAAAGTGACC
TTATTTGGTGATGAGTTGGCCTATCCAATTTTAGTCGACCCTTTTGCTTTCCAAAAAACCATGCATCCTGACGGTGAGCT
TGCTACTGTCAAAGGCGCTGGAGAGGCCAAAACAGCTTGTGTCATTAGCTCCTTTACCACCACCTCTTTAGAAGATATTC
AGCAAGTTGCGACCACGCCGATTTGGTTTCAGTTGTATATCCAAGATGACTTAGAATTTGCCAAAAAAGTGCTAAAACAA
GCAGAAGCGGCCGGCTGCAAAGCGGTGTGTATTACCCTAGATTCTGTTGCCGCGGCTGTACGCAATGAAGAAGACAAGGT
CGGCTTTGAGCTGTCTAAAGACTTAAACATGCCTTATAAGATTGGCCGGCCAGCCCCTGTCTCTTGGCAAGAAGTGGAAA
TGCTGATTGCTTATACTTCCTTGCCGGTACTGATTAAAGGCATCGTTAATGCTGAAGATGCACAACGAGCCCTTGATATT
GGCGCCTCTGGTATTATTGTTTCTAACCACGGAGGGCGTAAATTAGATACCGCGCCGCCAACCATTGAGGCATTACAGCG
AGTAGCTGAGCGTGTCGACCATAGAGTTCCCGTGCTCATCGATGGCGGTATCCGCCGTGGTACGGACGTCTTAAAGGCTT
TGGCTTTAGGCGCTGACGCAGTGCTATTAGGCAAACCGATTGCTCAAGCATTGGGAGCAGCAGGATCAGAGGGTGTGGCC
AAAGCGCTTAAAATCTTACAACATGAATTTGAAATGGCAATGACATTAACTGGGTACAACACCATTAATAGTATTGACCA
TTCGGTAATCTGGAAATAG

Upstream 100 bases:

>100_bases
GCTTTAATATTATTAACAGGCAAGCCCCGTACTGTGAAATTACTCTAAACCTGTCCAATTAAAAAACCTATTAATAATAA
ATATAAGGAGCTTTATAAAC

Downstream 100 bases:

>100_bases
CCCAATGATATTCATATTTTAATAGAGCGATCCAAGCGCTTATCCCTAAGTTTTATCACTAGATATTTAAAAATCGGTCT
GTCTTGCAGGCCGATTTTTT

Product: FMN-dependent alpha-hydroxy acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTHPSTDINADYEINDLSQVTNLFDFEVLAKKKMSKGAFAYVSTGAGDEITHQNNHRAYDHITLNPRVLNDAKKLDTKVT
LFGDELAYPILVDPFAFQKTMHPDGELATVKGAGEAKTACVISSFTTTSLEDIQQVATTPIWFQLYIQDDLEFAKKVLKQ
AEAAGCKAVCITLDSVAAAVRNEEDKVGFELSKDLNMPYKIGRPAPVSWQEVEMLIAYTSLPVLIKGIVNAEDAQRALDI
GASGIIVSNHGGRKLDTAPPTIEALQRVAERVDHRVPVLIDGGIRRGTDVLKALALGADAVLLGKPIAQALGAAGSEGVA
KALKILQHEFEMAMTLTGYNTINSIDHSVIWK

Sequences:

>Translated_352_residues
MTHPSTDINADYEINDLSQVTNLFDFEVLAKKKMSKGAFAYVSTGAGDEITHQNNHRAYDHITLNPRVLNDAKKLDTKVT
LFGDELAYPILVDPFAFQKTMHPDGELATVKGAGEAKTACVISSFTTTSLEDIQQVATTPIWFQLYIQDDLEFAKKVLKQ
AEAAGCKAVCITLDSVAAAVRNEEDKVGFELSKDLNMPYKIGRPAPVSWQEVEMLIAYTSLPVLIKGIVNAEDAQRALDI
GASGIIVSNHGGRKLDTAPPTIEALQRVAERVDHRVPVLIDGGIRRGTDVLKALALGADAVLLGKPIAQALGAAGSEGVA
KALKILQHEFEMAMTLTGYNTINSIDHSVIWK
>Mature_351_residues
THPSTDINADYEINDLSQVTNLFDFEVLAKKKMSKGAFAYVSTGAGDEITHQNNHRAYDHITLNPRVLNDAKKLDTKVTL
FGDELAYPILVDPFAFQKTMHPDGELATVKGAGEAKTACVISSFTTTSLEDIQQVATTPIWFQLYIQDDLEFAKKVLKQA
EAAGCKAVCITLDSVAAAVRNEEDKVGFELSKDLNMPYKIGRPAPVSWQEVEMLIAYTSLPVLIKGIVNAEDAQRALDIG
ASGIIVSNHGGRKLDTAPPTIEALQRVAERVDHRVPVLIDGGIRRGTDVLKALALGADAVLLGKPIAQALGAAGSEGVAK
ALKILQHEFEMAMTLTGYNTINSIDHSVIWK

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=343, Percent_Identity=37.3177842565598, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI7705393, Length=343, Percent_Identity=37.3177842565598, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI11068137, Length=361, Percent_Identity=36.5650969529086, Blast_Score=237, Evalue=1e-62,
Organism=Escherichia coli, GI1790033, Length=363, Percent_Identity=30.3030303030303, Blast_Score=184, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI193208036, Length=352, Percent_Identity=35.7954545454545, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI32566217, Length=265, Percent_Identity=32.4528301886792, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6323587, Length=352, Percent_Identity=36.6477272727273, Blast_Score=224, Evalue=2e-59,
Organism=Drosophila melanogaster, GI78707188, Length=350, Percent_Identity=35.1428571428571, Blast_Score=221, Evalue=7e-58,
Organism=Drosophila melanogaster, GI281363140, Length=350, Percent_Identity=35.1428571428571, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI78707190, Length=350, Percent_Identity=35.1428571428571, Blast_Score=220, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 38140; Mature: 38009

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPSTDINADYEINDLSQVTNLFDFEVLAKKKMSKGAFAYVSTGAGDEITHQNNHRAYD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEE
HITLNPRVLNDAKKLDTKVTLFGDELAYPILVDPFAFQKTMHPDGELATVKGAGEAKTAC
EEEECCHHHCCHHHCCCEEEEECCCCCCCEEECCHHHHHCCCCCCCEEEEECCCCCCEEE
VISSFTTTSLEDIQQVATTPIWFQLYIQDDLEFAKKVLKQAEAAGCKAVCITLDSVAAAV
EEECCCCCCHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHH
RNEEDKVGFELSKDLNMPYKIGRPAPVSWQEVEMLIAYTSLPVLIKGIVNAEDAQRALDI
CCCCCCCCEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GASGIIVSNHGGRKLDTAPPTIEALQRVAERVDHRVPVLIDGGIRRGTDVLKALALGADA
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCC
VLLGKPIAQALGAAGSEGVAKALKILQHEFEMAMTLTGYNTINSIDHSVIWK
EECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEECCCHHHCCCHHHCCC
>Mature Secondary Structure 
THPSTDINADYEINDLSQVTNLFDFEVLAKKKMSKGAFAYVSTGAGDEITHQNNHRAYD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEE
HITLNPRVLNDAKKLDTKVTLFGDELAYPILVDPFAFQKTMHPDGELATVKGAGEAKTAC
EEEECCHHHCCHHHCCCEEEEECCCCCCCEEECCHHHHHCCCCCCCEEEEECCCCCCEEE
VISSFTTTSLEDIQQVATTPIWFQLYIQDDLEFAKKVLKQAEAAGCKAVCITLDSVAAAV
EEECCCCCCHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHH
RNEEDKVGFELSKDLNMPYKIGRPAPVSWQEVEMLIAYTSLPVLIKGIVNAEDAQRALDI
CCCCCCCCEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GASGIIVSNHGGRKLDTAPPTIEALQRVAERVDHRVPVLIDGGIRRGTDVLKALALGADA
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCC
VLLGKPIAQALGAAGSEGVAKALKILQHEFEMAMTLTGYNTINSIDHSVIWK
EECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEECCCHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA