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The map label for this gene is ruvC

Identifier: 148653235

GI number: 148653235

Start: 1757863

End: 1758447

Strand: Direct

Name: ruvC

Synonym: PsycPRwf_1433

Alternate gene names: 148653235

Gene position: 1757863-1758447 (Clockwise)

Preceding gene: 148653231

Following gene: 148653242

Centisome position: 59.01

GC content: 49.23

Gene sequence:

>585_bases
ATGGCGATAATCATAGGTATTGACCCCGGCTCAAGAATGACCGGATATGGCATTATCCATCAAAAAGGCGATACCCTACG
CTATCTTGATGCAGGCACCATTCGCACCGATACTAAGGAGATGCCAGAGCGCTTAAAGCGAATATTCCAAGGCCTGACCC
GCATCACTCAGTACCATTTAAAATACTCAGATGAGCCCATCCACGCCGCAGTTGAACAGGTATTTATGGCCGAAAACCCC
GACTCTGCCCTAAAACTTGGCCAAGCACGTGGCGCCGCTATTGCCGCCTTGGTCGCCTTGGATTTGGAGGTATCAGAATA
CACCGCACGTCAGATTAAGCAGTCGGTATGTGGCTATGGCGCCGCTGATAAGGTACAAGTACAGGAGATGGTGTGCCGTA
TACTAAAACTTGATGTGACCCCTCAACAAGATGCAGCAGATGGTCTTGCTTGTGCGATTTGTCATGCTCACTCAAGCCAC
TCTATGAATAAGCTACTGATGAATAGCACACTACGTGGCCGCGGCACCTCTAAGAAGAAGGGCCGCTGGCGTTTAACTGA
AGAGGATTTAGCAAGCTTGAAATAA

Upstream 100 bases:

>100_bases
TGAAGCTTGTTTTGTTGCGCTTTAGCACAAAAAATCTCAAATAAAGTCAACAAGATGAGCGAAGAATAATTTTTATTTTT
TGAGGATTAAAAATAATAAT

Downstream 100 bases:

>100_bases
AACATTTAAGGCGTATCAGCAATGCCGTAAGGCGTATCAGCAATGGCGCTCTCCACCACGGCATCTAACACATAAACAAA
CTGCTTGCCCTTAACATCGA

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MAIIIGIDPGSRMTGYGIIHQKGDTLRYLDAGTIRTDTKEMPERLKRIFQGLTRITQYHLKYSDEPIHAAVEQVFMAENP
DSALKLGQARGAAIAALVALDLEVSEYTARQIKQSVCGYGAADKVQVQEMVCRILKLDVTPQQDAADGLACAICHAHSSH
SMNKLLMNSTLRGRGTSKKKGRWRLTEEDLASLK

Sequences:

>Translated_194_residues
MAIIIGIDPGSRMTGYGIIHQKGDTLRYLDAGTIRTDTKEMPERLKRIFQGLTRITQYHLKYSDEPIHAAVEQVFMAENP
DSALKLGQARGAAIAALVALDLEVSEYTARQIKQSVCGYGAADKVQVQEMVCRILKLDVTPQQDAADGLACAICHAHSSH
SMNKLLMNSTLRGRGTSKKKGRWRLTEEDLASLK
>Mature_193_residues
AIIIGIDPGSRMTGYGIIHQKGDTLRYLDAGTIRTDTKEMPERLKRIFQGLTRITQYHLKYSDEPIHAAVEQVFMAENPD
SALKLGQARGAAIAALVALDLEVSEYTARQIKQSVCGYGAADKVQVQEMVCRILKLDVTPQQDAADGLACAICHAHSSHS
MNKLLMNSTLRGRGTSKKKGRWRLTEEDLASLK

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=162, Percent_Identity=58.0246913580247, Blast_Score=162, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_PSYWF (A5WFD7)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001280328.1
- ProteinModelPortal:   A5WFD7
- SMR:   A5WFD7
- STRING:   A5WFD7
- GeneID:   5206604
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_1433
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- ProtClustDB:   PRK00039
- BioCyc:   PSP56811:PSYCPRWF_1433-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 21384; Mature: 21253

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIIIGIDPGSRMTGYGIIHQKGDTLRYLDAGTIRTDTKEMPERLKRIFQGLTRITQYHL
CEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KYSDEPIHAAVEQVFMAENPDSALKLGQARGAAIAALVALDLEVSEYTARQIKQSVCGYG
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
AADKVQVQEMVCRILKLDVTPQQDAADGLACAICHAHSSHSMNKLLMNSTLRGRGTSKKK
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHCCCCHHHHHHHHHCCCCCCCCCCCC
GRWRLTEEDLASLK
CCEEECHHHHHHCC
>Mature Secondary Structure 
AIIIGIDPGSRMTGYGIIHQKGDTLRYLDAGTIRTDTKEMPERLKRIFQGLTRITQYHL
EEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KYSDEPIHAAVEQVFMAENPDSALKLGQARGAAIAALVALDLEVSEYTARQIKQSVCGYG
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
AADKVQVQEMVCRILKLDVTPQQDAADGLACAICHAHSSHSMNKLLMNSTLRGRGTSKKK
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHCCCCHHHHHHHHHCCCCCCCCCCCC
GRWRLTEEDLASLK
CCEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA