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The map label for this gene is CYP127A1 [H]

Identifier: 148652819

GI number: 148652819

Start: 1204643

End: 1205806

Strand: Direct

Name: CYP127A1 [H]

Synonym: PsycPRwf_1012

Alternate gene names: 148652819

Gene position: 1204643-1205806 (Clockwise)

Preceding gene: 148652818

Following gene: 148652821

Centisome position: 40.44

GC content: 48.54

Gene sequence:

>1164_bases
ATGTTTGGCAATTCTAAAATCAAAGCGTTATATTCAGAAGATGATCAGCGAAGCCTGACAGATAAGCGGCGGCAGCAGCA
GGATATTATAAAAAACGAGGCCGGTGAGTGGGTACTGTTACGCCATGCTGATGTGAAGGCGGCGGCGCTTGATGATGCCA
CTTTCTCTAGTCATGTCTCGCGGTTTTTGCAAATCCCGAATGGCTTAGACGGCGCAGAGCATGATCAGTATAGAGCACTG
ATTAACCGCTATCTTAGTCAAGACGCCATTACCCCTTATGTGCCGCTGTTTCAACACGTGGCAACAGAGCTTGTATCGGG
GCTACCTAAAGGGGAGGTCATTAATGCGGTTACGGATATAGGCACTGTCTTTGCAGTACGTGCTCAGTGCCAATGGCTAG
GCTGGCCAGCAGAGGTTGAGCCTATCTTAGTACAATGGGTCAATGACAATCACCAAGCCAGCCGCTTAAAAGACCATACC
AAGCTTGCAACAGTAGCACAGGATTTTAATGAAATTATTCGCTCGGTTATCGCCCCATTTCGGGATACAGACTCTGCTGC
TGCTAGCCATAACAAAGCAAATCAAGACAGCATAACAGCTCAGCTATGCCGTGAGCAAATAAAGGGACGCCCACTTAGCG
AGGCGGAAATCGTGTCTATTTTGCGCAATTGGACTGGGGGTGATTTGGGGTCTATGGCATTATGTGTGGGCGTAGTGGTG
GCTTATCTTGCCCATCATCCTAAACAGTTACAGCACTGTGCCAATGCCTCTGATGCAGAGCTTGAAGCCATTATTGATGA
GATACTGCGTCTTGATAATCCTTTCCCCTCAAACCGTAGGATAACCAAGTGTCCGGTGACTCTAGGCGAGCATCAATTGC
CTGAAGGGGCTAAGGTGCATTTAGACTGGATTTCAGCAAACCGCGATGAGGCCGTATTTGGTAAAGATACCTTTGATCCA
GTCAGACATGCAGCGGATAATCTGGTCTATGGTATTGGCCGTCATGTGTGTCCTGGGCGATTATTGGCTACTTGGCAGCT
TAGAATCCTTATCCGAGCACTGCTTGCGCATGTAGAGGCGATCACGCCAGCGCCGAATGAGTCATTTGAACGGCAGCTGC
CTCCATTAGGTGGATATAGCCGTGTGCCTGTTGTTTTAAGTTAA

Upstream 100 bases:

>100_bases
GGTCTTGTGGTTGCGGTTAGACAGGATATAAAAGTGACTCAAGCCTTGTTTTATATTTATGATGTGATGTGATGTATAAG
TTGATTGTCTGGGAGGTATC

Downstream 100 bases:

>100_bases
TATTGTTATCTATTTTGGCTATACTTGACACCGTAAGACTAAAAAAGCAGCCCCTATTGACATAGTGGCTGCTTTTTTTA
TGCTATTGTTGATAACGCTA

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MFGNSKIKALYSEDDQRSLTDKRRQQQDIIKNEAGEWVLLRHADVKAAALDDATFSSHVSRFLQIPNGLDGAEHDQYRAL
INRYLSQDAITPYVPLFQHVATELVSGLPKGEVINAVTDIGTVFAVRAQCQWLGWPAEVEPILVQWVNDNHQASRLKDHT
KLATVAQDFNEIIRSVIAPFRDTDSAAASHNKANQDSITAQLCREQIKGRPLSEAEIVSILRNWTGGDLGSMALCVGVVV
AYLAHHPKQLQHCANASDAELEAIIDEILRLDNPFPSNRRITKCPVTLGEHQLPEGAKVHLDWISANRDEAVFGKDTFDP
VRHAADNLVYGIGRHVCPGRLLATWQLRILIRALLAHVEAITPAPNESFERQLPPLGGYSRVPVVLS

Sequences:

>Translated_387_residues
MFGNSKIKALYSEDDQRSLTDKRRQQQDIIKNEAGEWVLLRHADVKAAALDDATFSSHVSRFLQIPNGLDGAEHDQYRAL
INRYLSQDAITPYVPLFQHVATELVSGLPKGEVINAVTDIGTVFAVRAQCQWLGWPAEVEPILVQWVNDNHQASRLKDHT
KLATVAQDFNEIIRSVIAPFRDTDSAAASHNKANQDSITAQLCREQIKGRPLSEAEIVSILRNWTGGDLGSMALCVGVVV
AYLAHHPKQLQHCANASDAELEAIIDEILRLDNPFPSNRRITKCPVTLGEHQLPEGAKVHLDWISANRDEAVFGKDTFDP
VRHAADNLVYGIGRHVCPGRLLATWQLRILIRALLAHVEAITPAPNESFERQLPPLGGYSRVPVVLS
>Mature_387_residues
MFGNSKIKALYSEDDQRSLTDKRRQQQDIIKNEAGEWVLLRHADVKAAALDDATFSSHVSRFLQIPNGLDGAEHDQYRAL
INRYLSQDAITPYVPLFQHVATELVSGLPKGEVINAVTDIGTVFAVRAQCQWLGWPAEVEPILVQWVNDNHQASRLKDHT
KLATVAQDFNEIIRSVIAPFRDTDSAAASHNKANQDSITAQLCREQIKGRPLSEAEIVSILRNWTGGDLGSMALCVGVVV
AYLAHHPKQLQHCANASDAELEAIIDEILRLDNPFPSNRRITKCPVTLGEHQLPEGAKVHLDWISANRDEAVFGKDTFDP
VRHAADNLVYGIGRHVCPGRLLATWQLRILIRALLAHVEAITPAPNESFERQLPPLGGYSRVPVVLS

Specific function: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 42930; Mature: 42930

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGNSKIKALYSEDDQRSLTDKRRQQQDIIKNEAGEWVLLRHADVKAAALDDATFSSHVS
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCHHHHHHHHH
RFLQIPNGLDGAEHDQYRALINRYLSQDAITPYVPLFQHVATELVSGLPKGEVINAVTDI
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GTVFAVRAQCQWLGWPAEVEPILVQWVNDNHQASRLKDHTKLATVAQDFNEIIRSVIAPF
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RDTDSAAASHNKANQDSITAQLCREQIKGRPLSEAEIVSILRNWTGGDLGSMALCVGVVV
CCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
AYLAHHPKQLQHCANASDAELEAIIDEILRLDNPFPSNRRITKCPVTLGEHQLPEGAKVH
HHHHHCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCEEE
LDWISANRDEAVFGKDTFDPVRHAADNLVYGIGRHVCPGRLLATWQLRILIRALLAHVEA
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ITPAPNESFERQLPPLGGYSRVPVVLS
CCCCCCCHHHHCCCCCCCCCCCCEEEC
>Mature Secondary Structure
MFGNSKIKALYSEDDQRSLTDKRRQQQDIIKNEAGEWVLLRHADVKAAALDDATFSSHVS
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCHHHHHHHHH
RFLQIPNGLDGAEHDQYRALINRYLSQDAITPYVPLFQHVATELVSGLPKGEVINAVTDI
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GTVFAVRAQCQWLGWPAEVEPILVQWVNDNHQASRLKDHTKLATVAQDFNEIIRSVIAPF
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RDTDSAAASHNKANQDSITAQLCREQIKGRPLSEAEIVSILRNWTGGDLGSMALCVGVVV
CCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
AYLAHHPKQLQHCANASDAELEAIIDEILRLDNPFPSNRRITKCPVTLGEHQLPEGAKVH
HHHHHCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCEEE
LDWISANRDEAVFGKDTFDPVRHAADNLVYGIGRHVCPGRLLATWQLRILIRALLAHVEA
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ITPAPNESFERQLPPLGGYSRVPVVLS
CCCCCCCHHHHCCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]