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The map label for this gene is apaH [H]

Identifier: 148652715

GI number: 148652715

Start: 1080796

End: 1081632

Strand: Direct

Name: apaH [H]

Synonym: PsycPRwf_0908

Alternate gene names: 148652715

Gene position: 1080796-1081632 (Clockwise)

Preceding gene: 148652714

Following gene: 148652723

Centisome position: 36.28

GC content: 47.79

Gene sequence:

>837_bases
ATGAAGTACCGAGCCGAGTACGTAATCGGAGACCTACAAGGGTGTTATGCCGCTTATCTTGAGTTGTTAGATAAGATAGA
TTTTGACCCAAAGCAAGACAAGCTATGGTTTGTCGGCGATTTGGTGGCACGTGGCGAGGACTCATTGTCAACTTTGCGCC
ATGTCAAAACTCTGTGTGAGCAGGGTGCTGCTGCCACGGTACTGGGCAATCACGATATCAACTTAATTGCGGTTTGGCGT
GGTTTTGCGCCTTTAAAAAAGAAGGACAAAACTGAAGATATTATTAATGCACCTGATTGTGACGAGTTGTTAAATTGGCT
GCGTCGCCAGCCGCTGCTGCTTTGTCCAAACGAGCACACAGTGATGGTACACGCCGGTATCCCACCACACTGGAGTATCA
AACAGGCCAAACGCTATGCCCGTGAAGTCGAAACGCAGCTGTCTAGTAGCTTGTTTCAATTAAACCGAGTGTTGCCTAAG
CTTTATAGTGGTGAGGCCGATGAGTGGTCAGAGCACCTTAATGGCTTTACTCGTATTCGCGCCATTACCAACTACTTCAC
AAGAATGCGTCTGTGCAAAAAAGATGGTGCGCTTGAGTTTAACTTTAAGTCAAGCTTAACCGATGAGATGCCTGCTGATT
TTCGGCCTTGGTTTGAGTGGCAAGTGCCACGTGAGCGTAAGATATTGTTCGGTCACTGGGCAGCATTAAAGGCTGAGGTG
GATTTACCTAGTGCCAGAGCTTTAGATGGTGGCTGCGTGTGGGGCAATTGCTTGGTGGCTTATCGCTTAGAAGATGGCAA
GATATTTAGTGCCTCTGAGCGCTGCCCTAAAGACTAG

Upstream 100 bases:

>100_bases
TCGTGTTTTATGTCTAATAAACAAGCGGTTCACAGAGTGTCTGCTATAAAAACTCACCTGCAATAAGAGTAAATACTATC
AATTAATATAGAGTGATGCT

Downstream 100 bases:

>100_bases
GGACTGCAGCACACAAGGGGTAAATGCCAGACCTAAGCTTATCTTTAGTCAATGACAGGCATAAAAAATACGATGTTATC
TTAGTTGATAATATCGTATT

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKYRAEYVIGDLQGCYAAYLELLDKIDFDPKQDKLWFVGDLVARGEDSLSTLRHVKTLCEQGAAATVLGNHDINLIAVWR
GFAPLKKKDKTEDIINAPDCDELLNWLRRQPLLLCPNEHTVMVHAGIPPHWSIKQAKRYAREVETQLSSSLFQLNRVLPK
LYSGEADEWSEHLNGFTRIRAITNYFTRMRLCKKDGALEFNFKSSLTDEMPADFRPWFEWQVPRERKILFGHWAALKAEV
DLPSARALDGGCVWGNCLVAYRLEDGKIFSASERCPKD

Sequences:

>Translated_278_residues
MKYRAEYVIGDLQGCYAAYLELLDKIDFDPKQDKLWFVGDLVARGEDSLSTLRHVKTLCEQGAAATVLGNHDINLIAVWR
GFAPLKKKDKTEDIINAPDCDELLNWLRRQPLLLCPNEHTVMVHAGIPPHWSIKQAKRYAREVETQLSSSLFQLNRVLPK
LYSGEADEWSEHLNGFTRIRAITNYFTRMRLCKKDGALEFNFKSSLTDEMPADFRPWFEWQVPRERKILFGHWAALKAEV
DLPSARALDGGCVWGNCLVAYRLEDGKIFSASERCPKD
>Mature_278_residues
MKYRAEYVIGDLQGCYAAYLELLDKIDFDPKQDKLWFVGDLVARGEDSLSTLRHVKTLCEQGAAATVLGNHDINLIAVWR
GFAPLKKKDKTEDIINAPDCDELLNWLRRQPLLLCPNEHTVMVHAGIPPHWSIKQAKRYAREVETQLSSSLFQLNRVLPK
LYSGEADEWSEHLNGFTRIRAITNYFTRMRLCKKDGALEFNFKSSLTDEMPADFRPWFEWQVPRERKILFGHWAALKAEV
DLPSARALDGGCVWGNCLVAYRLEDGKIFSASERCPKD

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=277, Percent_Identity=45.8483754512635, Blast_Score=228, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31904; Mature: 31904

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRAEYVIGDLQGCYAAYLELLDKIDFDPKQDKLWFVGDLVARGEDSLSTLRHVKTLCE
CCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHH
QGAAATVLGNHDINLIAVWRGFAPLKKKDKTEDIINAPDCDELLNWLRRQPLLLCPNEHT
CCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCEEECCCCCE
VMVHAGIPPHWSIKQAKRYAREVETQLSSSLFQLNRVLPKLYSGEADEWSEHLNGFTRIR
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AITNYFTRMRLCKKDGALEFNFKSSLTDEMPADFRPWFEWQVPRERKILFGHWAALKAEV
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCEEEEEEHHHEEEEC
DLPSARALDGGCVWGNCLVAYRLEDGKIFSASERCPKD
CCCCCCCCCCCEEECCEEEEEEECCCCEECCCCCCCCC
>Mature Secondary Structure
MKYRAEYVIGDLQGCYAAYLELLDKIDFDPKQDKLWFVGDLVARGEDSLSTLRHVKTLCE
CCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHH
QGAAATVLGNHDINLIAVWRGFAPLKKKDKTEDIINAPDCDELLNWLRRQPLLLCPNEHT
CCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCEEECCCCCE
VMVHAGIPPHWSIKQAKRYAREVETQLSSSLFQLNRVLPKLYSGEADEWSEHLNGFTRIR
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AITNYFTRMRLCKKDGALEFNFKSSLTDEMPADFRPWFEWQVPRERKILFGHWAALKAEV
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCEEEEEEHHHEEEEC
DLPSARALDGGCVWGNCLVAYRLEDGKIFSASERCPKD
CCCCCCCCCCCEEECCEEEEEEECCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA