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The map label for this gene is queD [H]

Identifier: 148652626

GI number: 148652626

Start: 971267

End: 971860

Strand: Direct

Name: queD [H]

Synonym: PsycPRwf_0817

Alternate gene names: 148652626

Gene position: 971267-971860 (Clockwise)

Preceding gene: 148652625

Following gene: 148652627

Centisome position: 32.6

GC content: 42.93

Gene sequence:

>594_bases
ATGCGAATACGTAAGCTGTTTAAATTTGAAAACGCCCATATTGTGCGTAACTGCAGCTCGGATAGATGCAAGCGCTCTAT
TCATGGACACAGCTATCAAATTGAGCTGATTTTGCAAGCAGACAGACTAGATAATGGTCAAATGGTATATGACTTTGGCC
TGTTAAAATCCTCTATCAAAGACATTATTGATAGCTTTGATCATGCCATCTGTTTTTGGAACAAAGATGATCCTGAATAC
ATTGCAATGTGTAAAAAATTCAGCGCCCGCTGGATCAGCTTGCCGGTATCACCTTCAGCGGAGCAGTTTTCTCGGGTCAT
TTTCTTTTGGGCCCAAAGTATTTTAGAGCAGACCAAAATGGCCAATGGCGAGGCAGATGTCAGCGTCTATTCGGTGATTG
CTCATGAGACGGCAACTGGCTACGCACAGTGCTTTGCTGAAGATGTGAGCAACGAGCACATGGGTAAATTGGCGCTAGAG
GATTTTGAATTTAGCGATCAAATCAAGCAAGAGTGGAGTGATCCGGCAATGTATGACAAGCTAAAAGCAGGTGAAGCTTT
TATAAACCCTGAAGTGGCACTGCAAGTAAAATAA

Upstream 100 bases:

>100_bases
ACACTGACAGGTGTTATCCATTTTGTTTTTTGTCTATAGTGGTAAACTATGGCGTAATATCGAAAAAACCTATTGACTCT
AAGTTTTAGTGAGAATAATC

Downstream 100 bases:

>100_bases
TAATCAGCAGCTGATAACCAGTCATCAACCTATGGGCTACAAAGAGAATAAAAGGAGTGCCAATGACGCGCCGCAATGTA
CAGCTTACGCTAACCTCTGA

Product: 6-pyruvoyl-tetrahydropterin synthase-like protein

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MRIRKLFKFENAHIVRNCSSDRCKRSIHGHSYQIELILQADRLDNGQMVYDFGLLKSSIKDIIDSFDHAICFWNKDDPEY
IAMCKKFSARWISLPVSPSAEQFSRVIFFWAQSILEQTKMANGEADVSVYSVIAHETATGYAQCFAEDVSNEHMGKLALE
DFEFSDQIKQEWSDPAMYDKLKAGEAFINPEVALQVK

Sequences:

>Translated_197_residues
MRIRKLFKFENAHIVRNCSSDRCKRSIHGHSYQIELILQADRLDNGQMVYDFGLLKSSIKDIIDSFDHAICFWNKDDPEY
IAMCKKFSARWISLPVSPSAEQFSRVIFFWAQSILEQTKMANGEADVSVYSVIAHETATGYAQCFAEDVSNEHMGKLALE
DFEFSDQIKQEWSDPAMYDKLKAGEAFINPEVALQVK
>Mature_197_residues
MRIRKLFKFENAHIVRNCSSDRCKRSIHGHSYQIELILQADRLDNGQMVYDFGLLKSSIKDIIDSFDHAICFWNKDDPEY
IAMCKKFSARWISLPVSPSAEQFSRVIFFWAQSILEQTKMANGEADVSVYSVIAHETATGYAQCFAEDVSNEHMGKLALE
DFEFSDQIKQEWSDPAMYDKLKAGEAFINPEVALQVK

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 22634; Mature: 22634

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRKLFKFENAHIVRNCSSDRCKRSIHGHSYQIELILQADRLDNGQMVYDFGLLKSSIK
CCCHHHHHCCCCCEEECCCHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEHHHHHHHHHH
DIIDSFDHAICFWNKDDPEYIAMCKKFSARWISLPVSPSAEQFSRVIFFWAQSILEQTKM
HHHHHHCCEEEEECCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
ANGEADVSVYSVIAHETATGYAQCFAEDVSNEHMGKLALEDFEFSDQIKQEWSDPAMYDK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHCCCHHHHHHHHCCCCHHHHH
LKAGEAFINPEVALQVK
HHCCCEEECCCEEEEEC
>Mature Secondary Structure
MRIRKLFKFENAHIVRNCSSDRCKRSIHGHSYQIELILQADRLDNGQMVYDFGLLKSSIK
CCCHHHHHCCCCCEEECCCHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEHHHHHHHHHH
DIIDSFDHAICFWNKDDPEYIAMCKKFSARWISLPVSPSAEQFSRVIFFWAQSILEQTKM
HHHHHHCCEEEEECCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
ANGEADVSVYSVIAHETATGYAQCFAEDVSNEHMGKLALEDFEFSDQIKQEWSDPAMYDK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHCCCHHHHHHHHCCCCHHHHH
LKAGEAFINPEVALQVK
HHCCCEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]