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The map label for this gene is hisC2 [H]

Identifier: 148652316

GI number: 148652316

Start: 599288

End: 600391

Strand: Direct

Name: hisC2 [H]

Synonym: PsycPRwf_0504

Alternate gene names: 148652316

Gene position: 599288-600391 (Clockwise)

Preceding gene: 148652315

Following gene: 148652318

Centisome position: 20.12

GC content: 45.2

Gene sequence:

>1104_bases
ATGATAAAGACTATGGAATTTAAACTTGATACGCGATTGTGGTCTACAAAAGCACGTAATTTAAACCCCTATGTACCCGG
AGAGCAGCCCAAGCACGATAATTTGTGCAAGCTAAATACCAACGAAAACCCGTTTCCGCCTTCCCCCAAAGTTGTAGAGG
CCATTACGGCCGCTTTAAGTCATGGCGGTGATCAATTGCGTCTGTATCCGGCACCTGAGTCTGATGCATTAAGGCAGGCT
TTGGCTGATGCTTATGATTTACAGCTCAATCAAGTCTTTGTTGGTAATGGCTCAGATGAGGTTTTGGCGCTAGTATTTGC
CAGCTTTTTTATGAAAGAGCGCCCATTATTGGCGCCGGATATCAGCTATAGTTTTTATCCGGTATACGCCGATACTTTTG
GCATTGATTTAGTAAAAATCCCATTGCGTGATGATTTTAGTATTGAGACTGATGATTATCGTCAGCCTTGCTCAGGCATT
ATTATTGCTAACCCCAATGCGCCCACTGGTATCTTAATGTCACTTGAGGCCATTGATAAGCTAGCCACTGAGCACCCCAA
TGCAGTGATTGTGATTGATGAGGCTTATATTGATTTTGCCAGTACCGAGCAGGCGTCAGCCATCCGCTTAATTGAGACGC
ATGATAATCTACTGGTTACCCAAACCTTCTCAAAATCACGCTCATTGGCAGGGCTGCGTGTGGGTATGGCTTTTGGTAAT
CCTTCATTAATTGAAGCGTTAACCCGCATGAAAAACAGCTTTAATAGCTATCCACTAGACCGTTTGGCACAAGCGGGAGC
CTTAGCCAGTGTAGAAGATAAGCTGTATTTTAAGAGTACCTGTGAGCAAGTCATTGCACTACGCGAACAGCTAATTGAGC
AATTAAGCTCGCTTAACTTCACGGTATTGCCATCACAAGCCAACTTTGTGTTTGCCCGCCCACAGCAGGGCAATGCCAGC
GAAGTCGCCCAGCAGCTGCGTGAGCAAGGCATTATCGTGCGTTATTTTAATCAGCCAAGAATTAATGAATATTTGCGCAT
TACTGTGGGTACTGCTGAGCAAAACCGACGTTTGATTGGCGCCTTACAGCAGATGGCCGGTTAA

Upstream 100 bases:

>100_bases
TTGAACTTGCCCTTAATATCTTAATTGAATGAAGTGAGTAAGACCAAGTTATTGCGTATTGTAATGGCTGGCCACACTTC
ATATCACCCCTTATAAAAAG

Downstream 100 bases:

>100_bases
TCCGTATTGTCTTTCTGCCTTGCGTTTCTGTCTTGTCTTTCTGCCTTGATTGCATGGCCATTTAGCAAGACATGCATAAA
AAAGGACACCGATCGGTGTC

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MIKTMEFKLDTRLWSTKARNLNPYVPGEQPKHDNLCKLNTNENPFPPSPKVVEAITAALSHGGDQLRLYPAPESDALRQA
LADAYDLQLNQVFVGNGSDEVLALVFASFFMKERPLLAPDISYSFYPVYADTFGIDLVKIPLRDDFSIETDDYRQPCSGI
IIANPNAPTGILMSLEAIDKLATEHPNAVIVIDEAYIDFASTEQASAIRLIETHDNLLVTQTFSKSRSLAGLRVGMAFGN
PSLIEALTRMKNSFNSYPLDRLAQAGALASVEDKLYFKSTCEQVIALREQLIEQLSSLNFTVLPSQANFVFARPQQGNAS
EVAQQLREQGIIVRYFNQPRINEYLRITVGTAEQNRRLIGALQQMAG

Sequences:

>Translated_367_residues
MIKTMEFKLDTRLWSTKARNLNPYVPGEQPKHDNLCKLNTNENPFPPSPKVVEAITAALSHGGDQLRLYPAPESDALRQA
LADAYDLQLNQVFVGNGSDEVLALVFASFFMKERPLLAPDISYSFYPVYADTFGIDLVKIPLRDDFSIETDDYRQPCSGI
IIANPNAPTGILMSLEAIDKLATEHPNAVIVIDEAYIDFASTEQASAIRLIETHDNLLVTQTFSKSRSLAGLRVGMAFGN
PSLIEALTRMKNSFNSYPLDRLAQAGALASVEDKLYFKSTCEQVIALREQLIEQLSSLNFTVLPSQANFVFARPQQGNAS
EVAQQLREQGIIVRYFNQPRINEYLRITVGTAEQNRRLIGALQQMAG
>Mature_367_residues
MIKTMEFKLDTRLWSTKARNLNPYVPGEQPKHDNLCKLNTNENPFPPSPKVVEAITAALSHGGDQLRLYPAPESDALRQA
LADAYDLQLNQVFVGNGSDEVLALVFASFFMKERPLLAPDISYSFYPVYADTFGIDLVKIPLRDDFSIETDDYRQPCSGI
IIANPNAPTGILMSLEAIDKLATEHPNAVIVIDEAYIDFASTEQASAIRLIETHDNLLVTQTFSKSRSLAGLRVGMAFGN
PSLIEALTRMKNSFNSYPLDRLAQAGALASVEDKLYFKSTCEQVIALREQLIEQLSSLNFTVLPSQANFVFARPQQGNAS
EVAQQLREQGIIVRYFNQPRINEYLRITVGTAEQNRRLIGALQQMAG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=367, Percent_Identity=31.0626702997275, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788722, Length=289, Percent_Identity=26.643598615917, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322075, Length=395, Percent_Identity=28.1012658227848, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40807; Mature: 40807

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTMEFKLDTRLWSTKARNLNPYVPGEQPKHDNLCKLNTNENPFPPSPKVVEAITAALS
CCCEEEEEECHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
HGGDQLRLYPAPESDALRQALADAYDLQLNQVFVGNGSDEVLALVFASFFMKERPLLAPD
CCCCEEEEEECCCHHHHHHHHHHHHCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCC
ISYSFYPVYADTFGIDLVKIPLRDDFSIETDDYRQPCSGIIIANPNAPTGILMSLEAIDK
CCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCHHEEEHHHHHH
LATEHPNAVIVIDEAYIDFASTEQASAIRLIETHDNLLVTQTFSKSRSLAGLRVGMAFGN
HHHCCCCEEEEEEHHEECCCCCCCCCEEEEEECCCCEEEEEEHHCCCCCCEEEEEEECCC
PSLIEALTRMKNSFNSYPLDRLAQAGALASVEDKLYFKSTCEQVIALREQLIEQLSSLNF
HHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
TVLPSQANFVFARPQQGNASEVAQQLREQGIIVRYFNQPRINEYLRITVGTAEQNRRLIG
EEEECCCCEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCEEEEEEECCHHHHHHHH
ALQQMAG
HHHHHCC
>Mature Secondary Structure
MIKTMEFKLDTRLWSTKARNLNPYVPGEQPKHDNLCKLNTNENPFPPSPKVVEAITAALS
CCCEEEEEECHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
HGGDQLRLYPAPESDALRQALADAYDLQLNQVFVGNGSDEVLALVFASFFMKERPLLAPD
CCCCEEEEEECCCHHHHHHHHHHHHCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCC
ISYSFYPVYADTFGIDLVKIPLRDDFSIETDDYRQPCSGIIIANPNAPTGILMSLEAIDK
CCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCHHEEEHHHHHH
LATEHPNAVIVIDEAYIDFASTEQASAIRLIETHDNLLVTQTFSKSRSLAGLRVGMAFGN
HHHCCCCEEEEEEHHEECCCCCCCCCEEEEEECCCCEEEEEEHHCCCCCCEEEEEEECCC
PSLIEALTRMKNSFNSYPLDRLAQAGALASVEDKLYFKSTCEQVIALREQLIEQLSSLNF
HHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
TVLPSQANFVFARPQQGNASEVAQQLREQGIIVRYFNQPRINEYLRITVGTAEQNRRLIG
EEEECCCCEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCEEEEEEECCHHHHHHHH
ALQQMAG
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA