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The map label for this gene is yfjP [H]

Identifier: 148652307

GI number: 148652307

Start: 590399

End: 591094

Strand: Direct

Name: yfjP [H]

Synonym: PsycPRwf_0495

Alternate gene names: 148652307

Gene position: 590399-591094 (Clockwise)

Preceding gene: 148652306

Following gene: 148652309

Centisome position: 19.82

GC content: 50.57

Gene sequence:

>696_bases
ATGAAACACTCCTCTGTAAACCGTCAGCCCTCTGTATTCAAACTGCCCAGCGAGCCAGCCTGTAACCTGATACAGACTAT
GAATGATCTTAGCGAGCTTGAGGGTCATATTAAACAATTGATTGACATTGAACCTCGATTTGCCCCCATTTATCAGCAGC
TAGGGGTACCAAGCCTGCGCCGTAATCGCGGCGGCTTTAGAGAGTTGATGCGAGCGATGGTTGGTCAGCAGCTGTCGGTA
GCAGCAGCAAGCAGCATATGGAGTAAGCTTGAGAATGCGGCACTGATTACCCCAGATGCGATAATGAAAGCCGATGATGA
TACGCTACGCTCCCATGGCTTATCTAGACAAAAAATTCGTTATATACGCTCCTTGGTCGAGCATGATATTGACTTTGAGG
CATTGGCTCATTTGCCGGATGAGGCAGTCATCTCGGAGTTAACCGCGGTCACTGGTATTGGCAAATGGACGGCGCAGATG
TATCTATTGTTTAGTCTGGGGCGCGCCGATATATTGGCGGTAGATGATCTGGCTATTAAGGTGGGTGCCATGGAGGTGCT
AGGGCTTGATGAGCGACCCACGCCAAAGCAGCTAGAACGCTTAACCCAAAGCTGGTCACCGCATCGCAGCGCCGCAAGCT
TATTGCTATGGGCGCATTATGGCTGGCTAAAAGACCAAGAGGCAGTGCCGGTTTAG

Upstream 100 bases:

>100_bases
GGGCCTGAATGACTGCGGTGAGTCAGGCAATCCATAGCATCTTCATTAAATGAAATCATCCAATCAATGATAATGTCCGC
CAAGGAGACAGTCGCTGCTC

Downstream 100 bases:

>100_bases
GTATGGTTTAACCGCTACTAGCCTAAAAACTATTCAGATTTTTGTAAGTCAAGCAGCCTCTGGTACAAAGTATTTTTCTT
AACGCCGGTAAGCTCAGAGG

Product: HhH-GPD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKHSSVNRQPSVFKLPSEPACNLIQTMNDLSELEGHIKQLIDIEPRFAPIYQQLGVPSLRRNRGGFRELMRAMVGQQLSV
AAASSIWSKLENAALITPDAIMKADDDTLRSHGLSRQKIRYIRSLVEHDIDFEALAHLPDEAVISELTAVTGIGKWTAQM
YLLFSLGRADILAVDDLAIKVGAMEVLGLDERPTPKQLERLTQSWSPHRSAASLLLWAHYGWLKDQEAVPV

Sequences:

>Translated_231_residues
MKHSSVNRQPSVFKLPSEPACNLIQTMNDLSELEGHIKQLIDIEPRFAPIYQQLGVPSLRRNRGGFRELMRAMVGQQLSV
AAASSIWSKLENAALITPDAIMKADDDTLRSHGLSRQKIRYIRSLVEHDIDFEALAHLPDEAVISELTAVTGIGKWTAQM
YLLFSLGRADILAVDDLAIKVGAMEVLGLDERPTPKQLERLTQSWSPHRSAASLLLWAHYGWLKDQEAVPV
>Mature_231_residues
MKHSSVNRQPSVFKLPSEPACNLIQTMNDLSELEGHIKQLIDIEPRFAPIYQQLGVPSLRRNRGGFRELMRAMVGQQLSV
AAASSIWSKLENAALITPDAIMKADDDTLRSHGLSRQKIRYIRSLVEHDIDFEALAHLPDEAVISELTAVTGIGKWTAQM
YLLFSLGRADILAVDDLAIKVGAMEVLGLDERPTPKQLERLTQSWSPHRSAASLLLWAHYGWLKDQEAVPV

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Escherichia coli, GI1788383, Length=175, Percent_Identity=26.8571428571429, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 25800; Mature: 25800

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHSSVNRQPSVFKLPSEPACNLIQTMNDLSELEGHIKQLIDIEPRFAPIYQQLGVPSLR
CCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHH
RNRGGFRELMRAMVGQQLSVAAASSIWSKLENAALITPDAIMKADDDTLRSHGLSRQKIR
HCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEECCHHHHCCCCHHHHHCCCCHHHHH
YIRSLVEHDIDFEALAHLPDEAVISELTAVTGIGKWTAQMYLLFSLGRADILAVDDLAIK
HHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEHHHHHHH
VGAMEVLGLDERPTPKQLERLTQSWSPHRSAASLLLWAHYGWLKDQEAVPV
HHHHHEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKHSSVNRQPSVFKLPSEPACNLIQTMNDLSELEGHIKQLIDIEPRFAPIYQQLGVPSLR
CCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHH
RNRGGFRELMRAMVGQQLSVAAASSIWSKLENAALITPDAIMKADDDTLRSHGLSRQKIR
HCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEECCHHHHCCCCHHHHHCCCCHHHHH
YIRSLVEHDIDFEALAHLPDEAVISELTAVTGIGKWTAQMYLLFSLGRADILAVDDLAIK
HHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEHHHHHHH
VGAMEVLGLDERPTPKQLERLTQSWSPHRSAASLLLWAHYGWLKDQEAVPV
HHHHHEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]