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The map label for this gene is caiD [C]

Identifier: 148652200

GI number: 148652200

Start: 469186

End: 470013

Strand: Direct

Name: caiD [C]

Synonym: PsycPRwf_0388

Alternate gene names: 148652200

Gene position: 469186-470013 (Clockwise)

Preceding gene: 148652199

Following gene: 148652201

Centisome position: 15.75

GC content: 45.41

Gene sequence:

>828_bases
ATGTCATCTTTATTCAGTCAAAAATTAAATGAAAAATACACCACATTGGCGTTAAGTGAGGCCGATGAGGTGTTGACCGT
CTCGCTCAATCGCCCGGACAAAAAAAACGCCATGAGCCTGCGTATGATGCGTGAGCTTATCGATGTGGCTGAGCGCCTAA
AAAAAGACCATAGCATCCGTTCAGTGATTATCAATGGGGCAGGTGATAGCTTTTGTGCCGGTATTGATCTTAGTGACTTA
AACAATCCCAAAAATGCCATGATGGGCTTGTATGAGCTGCTAAAGCCTACCCAAAGTATCTTTCAAAGAGTATGTTTAAT
ATGGCGTGAAGTGCCAGTGCCGGTGATTGTGGTTACCCAAGGTTATTGTATTGGGGCAGGCATGCAACTGGCTTTAGCCT
GTGATTTTCGTATCTCCACCCCCGATTGTCAGTTTGCGATTATGGAGGCCAAATGGGGCTTAGTGCCCGACATGGGATTG
ACTCAGTCAGCCCTTCATGTGTTGCCAGTAGATGTCCTAAAAGAGCTGACCATGACCGCGCGCTTAATTGATGCCAAGCA
AGCTGAGCAGCTGCACTTAGTCACTCACATTGACGATACTCCTTATGAGCGTGCGCAAGCTTTGGCCACAGAGATTGCCA
CCCGTTCACCTGATGCCGTATTGGCCAGTAAACGGGTCATTAATCAGATGACCAAACAAAGCTTTTGTGCTTTGTATCAA
GAAAAAATGTGGCAACTTAAGCTGATGGGCGGGGGCAAAAACCGTAAATTAGCGATAAAAAAAGCCAAAGACAATAGTGT
GCAGTTTTTAAAGCGTCAATTTAGTTAG

Upstream 100 bases:

>100_bases
GATGAGAAAGCATTAAGTGAAAATGATATGACTTGGAAAATGATCTAACCCTATAAAGTTAACGGAACTGACCTTAACTA
ATCCTAAGCAGAGAGCTAAT

Downstream 100 bases:

>100_bases
GGGCGACATAGCCGGTAGTGAGCACTGCGTTATTTTGAAACTAAAAGCCCAGTCATGAGCCCAGTAAGCGATAAAACCTA
CTGGGCTTTTTGGTTTTTAA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSSLFSQKLNEKYTTLALSEADEVLTVSLNRPDKKNAMSLRMMRELIDVAERLKKDHSIRSVIINGAGDSFCAGIDLSDL
NNPKNAMMGLYELLKPTQSIFQRVCLIWREVPVPVIVVTQGYCIGAGMQLALACDFRISTPDCQFAIMEAKWGLVPDMGL
TQSALHVLPVDVLKELTMTARLIDAKQAEQLHLVTHIDDTPYERAQALATEIATRSPDAVLASKRVINQMTKQSFCALYQ
EKMWQLKLMGGGKNRKLAIKKAKDNSVQFLKRQFS

Sequences:

>Translated_275_residues
MSSLFSQKLNEKYTTLALSEADEVLTVSLNRPDKKNAMSLRMMRELIDVAERLKKDHSIRSVIINGAGDSFCAGIDLSDL
NNPKNAMMGLYELLKPTQSIFQRVCLIWREVPVPVIVVTQGYCIGAGMQLALACDFRISTPDCQFAIMEAKWGLVPDMGL
TQSALHVLPVDVLKELTMTARLIDAKQAEQLHLVTHIDDTPYERAQALATEIATRSPDAVLASKRVINQMTKQSFCALYQ
EKMWQLKLMGGGKNRKLAIKKAKDNSVQFLKRQFS
>Mature_274_residues
SSLFSQKLNEKYTTLALSEADEVLTVSLNRPDKKNAMSLRMMRELIDVAERLKKDHSIRSVIINGAGDSFCAGIDLSDLN
NPKNAMMGLYELLKPTQSIFQRVCLIWREVPVPVIVVTQGYCIGAGMQLALACDFRISTPDCQFAIMEAKWGLVPDMGLT
QSALHVLPVDVLKELTMTARLIDAKQAEQLHLVTHIDDTPYERAQALATEIATRSPDAVLASKRVINQMTKQSFCALYQE
KMWQLKLMGGGKNRKLAIKKAKDNSVQFLKRQFS

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=227, Percent_Identity=35.6828193832599, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI4502327, Length=213, Percent_Identity=30.0469483568075, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI194097323, Length=209, Percent_Identity=28.2296650717703, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI213417737, Length=264, Percent_Identity=26.1363636363636, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI157694516, Length=264, Percent_Identity=26.1363636363636, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI68989263, Length=237, Percent_Identity=24.8945147679325, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI37594469, Length=151, Percent_Identity=29.8013245033113, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI37594471, Length=148, Percent_Identity=28.3783783783784, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI157694520, Length=242, Percent_Identity=25.6198347107438, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI20127408, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787659, Length=235, Percent_Identity=29.3617021276596, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI221142681, Length=237, Percent_Identity=28.2700421940928, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788682, Length=198, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787660, Length=208, Percent_Identity=29.8076923076923, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790281, Length=180, Percent_Identity=23.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=214, Percent_Identity=32.7102803738318, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17534483, Length=240, Percent_Identity=32.5, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17536985, Length=232, Percent_Identity=31.4655172413793, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17554946, Length=227, Percent_Identity=27.7533039647577, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=210, Percent_Identity=25.2380952380952, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17558304, Length=237, Percent_Identity=25.7383966244726, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25145438, Length=217, Percent_Identity=26.2672811059908, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25144276, Length=181, Percent_Identity=29.2817679558011, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508953, Length=181, Percent_Identity=29.2817679558011, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17508951, Length=181, Percent_Identity=29.2817679558011, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=198, Percent_Identity=28.7878787878788, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24653139, Length=222, Percent_Identity=31.0810810810811, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19920382, Length=236, Percent_Identity=30.0847457627119, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20129971, Length=223, Percent_Identity=27.8026905829596, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653477, Length=223, Percent_Identity=27.8026905829596, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357171, Length=200, Percent_Identity=28, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45550169, Length=222, Percent_Identity=26.1261261261261, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24654903, Length=187, Percent_Identity=24.0641711229947, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921018, Length=203, Percent_Identity=21.1822660098522, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 30777; Mature: 30646

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLFSQKLNEKYTTLALSEADEVLTVSLNRPDKKNAMSLRMMRELIDVAERLKKDHSIR
CCHHHHHHHCCHHHEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
SVIINGAGDSFCAGIDLSDLNNPKNAMMGLYELLKPTQSIFQRVCLIWREVPVPVIVVTQ
EEEEECCCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GYCIGAGMQLALACDFRISTPDCQFAIMEAKWGLVPDMGLTQSALHVLPVDVLKELTMTA
CEEECCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RLIDAKQAEQLHLVTHIDDTPYERAQALATEIATRSPDAVLASKRVINQMTKQSFCALYQ
HHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EKMWQLKLMGGGKNRKLAIKKAKDNSVQFLKRQFS
HHHHEEEEECCCCCCEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
SSLFSQKLNEKYTTLALSEADEVLTVSLNRPDKKNAMSLRMMRELIDVAERLKKDHSIR
CHHHHHHHCCHHHEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
SVIINGAGDSFCAGIDLSDLNNPKNAMMGLYELLKPTQSIFQRVCLIWREVPVPVIVVTQ
EEEEECCCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GYCIGAGMQLALACDFRISTPDCQFAIMEAKWGLVPDMGLTQSALHVLPVDVLKELTMTA
CEEECCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RLIDAKQAEQLHLVTHIDDTPYERAQALATEIATRSPDAVLASKRVINQMTKQSFCALYQ
HHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EKMWQLKLMGGGKNRKLAIKKAKDNSVQFLKRQFS
HHHHEEEEECCCCCCEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA