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The map label for this gene is pyrF [H]

Identifier: 148643677

GI number: 148643677

Start: 1677856

End: 1678497

Strand: Reverse

Name: pyrF [H]

Synonym: Msm_1617

Alternate gene names: 148643677

Gene position: 1678497-1677856 (Counterclockwise)

Preceding gene: 148643687

Following gene: 148643668

Centisome position: 90.57

GC content: 33.33

Gene sequence:

>642_bases
ATGAATATTAAAAATAACTTAATATTAGCACTTGATGTAACCAATAAAGACAAAGCAATTGAAATATGTAAAGAAGTAAG
CCCCTATATCAATACAATAAAAATAGGATATCCATTGACATTAGCTGAAGGATTAGAAATCATTAAAATTATAAAAGATG
AATTTGGTGCAAATATAATCTGCGATTATAAAGTTGCAGACATTGACGCTACCAATTCCAAAATCTGCGATTTAACATTT
GATGCAGGAGCAGATGCAATAATCTGTCACGGTTTTGTAGGTTCCGACAGTGTTCAGGCTTGTCTAGACAGTGCAAATAA
ACACGAAAAAGAAATATTTTTACTTACTGAAATGTCACATCCGGGAGCTAAAATGTTTTTACAAAAAGATGCTGAAGCTA
TAGCTAAAATGGGAGTTGATATGGGAATTACCAATTATGTTGCACCGGCTACAAGATTAGACAGATTAAGTGAAATAAGA
AACATTGTAGGTGATGATGCCTGCATTATTTCTCCAGGTGTCGGAAAACAGGGTGGAGATGCTAAAAAAACTCTTGAATT
TGCAAGTGCCATTATTGTTGGAAGAAGCATTTATGAATCAGATAATCCTGCACTGGCCTGTGAAAAAATAATAAAGGATT
AA

Upstream 100 bases:

>100_bases
TATTACTAAATTAAGTACACCAAAAAATAATTCCTAATTTATATAACTGTTAAAATACAATAAATATAAACCAACTACAA
ATTACTAAAGGCGATTCCAA

Downstream 100 bases:

>100_bases
AAAATCCTTTTTAAATTCTACTTTTTTTAAATAAACCATTTTCAGATATTGAACCTGCAACTAGGTATGCGAACTCAAAT
AATATAAACAATACAAAGAA

Product: orotidine-5'-phosphate decarboxylase, PyrF

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MNIKNNLILALDVTNKDKAIEICKEVSPYINTIKIGYPLTLAEGLEIIKIIKDEFGANIICDYKVADIDATNSKICDLTF
DAGADAIICHGFVGSDSVQACLDSANKHEKEIFLLTEMSHPGAKMFLQKDAEAIAKMGVDMGITNYVAPATRLDRLSEIR
NIVGDDACIISPGVGKQGGDAKKTLEFASAIIVGRSIYESDNPALACEKIIKD

Sequences:

>Translated_213_residues
MNIKNNLILALDVTNKDKAIEICKEVSPYINTIKIGYPLTLAEGLEIIKIIKDEFGANIICDYKVADIDATNSKICDLTF
DAGADAIICHGFVGSDSVQACLDSANKHEKEIFLLTEMSHPGAKMFLQKDAEAIAKMGVDMGITNYVAPATRLDRLSEIR
NIVGDDACIISPGVGKQGGDAKKTLEFASAIIVGRSIYESDNPALACEKIIKD
>Mature_213_residues
MNIKNNLILALDVTNKDKAIEICKEVSPYINTIKIGYPLTLAEGLEIIKIIKDEFGANIICDYKVADIDATNSKICDLTF
DAGADAIICHGFVGSDSVQACLDSANKHEKEIFLLTEMSHPGAKMFLQKDAEAIAKMGVDMGITNYVAPATRLDRLSEIR
NIVGDDACIISPGVGKQGGDAKKTLEFASAIIVGRSIYESDNPALACEKIIKD

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 22983; Mature: 22983

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKNNLILALDVTNKDKAIEICKEVSPYINTIKIGYPLTLAEGLEIIKIIKDEFGANII
CCCCCCEEEEEEECCCHHHHHHHHHHCHHHCEEEECCCEEHHHHHHHHHHHHHHHCCCEE
CDYKVADIDATNSKICDLTFDAGADAIICHGFVGSDSVQACLDSANKHEKEIFLLTEMSH
EEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEEECCC
PGAKMFLQKDAEAIAKMGVDMGITNYVAPATRLDRLSEIRNIVGDDACIISPGVGKQGGD
CCHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
AKKTLEFASAIIVGRSIYESDNPALACEKIIKD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNIKNNLILALDVTNKDKAIEICKEVSPYINTIKIGYPLTLAEGLEIIKIIKDEFGANII
CCCCCCEEEEEEECCCHHHHHHHHHHCHHHCEEEECCCEEHHHHHHHHHHHHHHHCCCEE
CDYKVADIDATNSKICDLTFDAGADAIICHGFVGSDSVQACLDSANKHEKEIFLLTEMSH
EEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEEECCC
PGAKMFLQKDAEAIAKMGVDMGITNYVAPATRLDRLSEIRNIVGDDACIISPGVGKQGGD
CCHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
AKKTLEFASAIIVGRSIYESDNPALACEKIIKD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463; 10681441 [H]