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The map label for this gene is aroC

Identifier: 148643534

GI number: 148643534

Start: 1499415

End: 1500509

Strand: Reverse

Name: aroC

Synonym: Msm_1474

Alternate gene names: 148643534

Gene position: 1500509-1499415 (Counterclockwise)

Preceding gene: 148643540

Following gene: 148643531

Centisome position: 80.97

GC content: 37.08

Gene sequence:

>1095_bases
ATGGCAAATACTATCGGAAAAATGTTTTCAGTAACCAGTTTTGGATCCAGCCACGGAAAAGCTGTAGGAGCAGTTATTGA
TGGATGTCCTGCCAATCTTGAATTAAACACTGAAGATATTCAAAAAGAACTGGATAAACGAAAACCTGGAACCAGCGGAG
TAACAACACCACGTAAAGAAGAAGATAAAGTTCAGATTTTATCAGGAATTTTTGAGGGTAAAACTGACGGAACACCAATT
ACAGGAGTTGTCTATAACAACAACCAGCATTCCAAAGATTATTCCATGTTTAAAAATACTCCCCGCCCATCTCATGGAGA
TTATGGCTGGATGAGCAAATACGGCAATTATGACTACAATGGAGGAGGTCGAGGAAGCGGAAGAATCACTATCGGCCATG
TAATTGCAGGAGCAATAGCTAAAAAGCTTTTAAAAACAAAAAATATTGAAATTGTTTCACAAGTTATTCAAATCGGAGAC
ATAATGGCTCACAGCAATGATTTTGATACTGTAAAAGAAAATGTTGAGAAAAATTCTGTAAGATGCGGTGATCTGGAAGC
TGCTAAAGCTATGGAAGAATTAATTTTATCTAAAAAACAGGAAGGTGATTCAATTGGAGGAATCGTTGAAACAGTCGCTG
TAGGAGTTCCTGCAGGACTTGGCGAACCTGTATTTGAAAGACTTGATGGTGATTTAGCTAGAATTTTAATGAATATAAAT
GCTGTAAAAGGAGTGGAAATCGGTTTTGGTTTTGATGTAGCTACCAGCTGCGCATCAGAGATTAATGATGAATATTATAT
TGAAGATAATAAAATTTACACTTCAACCAACAGTTCAGGAGGAATTATTGGTGGAATAAGCAATGGCATGCCAATAATTT
CAAGGATTGCAGTTAAACCAACCCCTTCAATTTCAAAATGTCAAAAATCAGTTAATTTAGAAAAAATGGAAGCAGAAGAC
ATAACTATTCAGGGAAGACATGACCCCTGCATCTGTCCAAGAGCTACTGTTGTAGCCCAATCCAGTGTAGCTATTGTTCT
TGCAGACCATATGATTAGATCAGGATACATCCATCCTTCCAATCTGGAAATCTAA

Upstream 100 bases:

>100_bases
AATCAGATTAATATTATTTTCAGTCATACCACTCAACAAAACATTTATTAGATTTATATTATATTACTATGAATATAAGA
TTTTTATTGGAGAAACAACT

Downstream 100 bases:

>100_bases
TCAGTTTTTTCCAATAGTAAGCTCATCATTTTCTCCATTTTTTAATGAAGATTGATAAGTGTTTTTTCTCTCCATTCTAT
TTAAATCAATGTTTGAACTG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MANTIGKMFSVTSFGSSHGKAVGAVIDGCPANLELNTEDIQKELDKRKPGTSGVTTPRKEEDKVQILSGIFEGKTDGTPI
TGVVYNNNQHSKDYSMFKNTPRPSHGDYGWMSKYGNYDYNGGGRGSGRITIGHVIAGAIAKKLLKTKNIEIVSQVIQIGD
IMAHSNDFDTVKENVEKNSVRCGDLEAAKAMEELILSKKQEGDSIGGIVETVAVGVPAGLGEPVFERLDGDLARILMNIN
AVKGVEIGFGFDVATSCASEINDEYYIEDNKIYTSTNSSGGIIGGISNGMPIISRIAVKPTPSISKCQKSVNLEKMEAED
ITIQGRHDPCICPRATVVAQSSVAIVLADHMIRSGYIHPSNLEI

Sequences:

>Translated_364_residues
MANTIGKMFSVTSFGSSHGKAVGAVIDGCPANLELNTEDIQKELDKRKPGTSGVTTPRKEEDKVQILSGIFEGKTDGTPI
TGVVYNNNQHSKDYSMFKNTPRPSHGDYGWMSKYGNYDYNGGGRGSGRITIGHVIAGAIAKKLLKTKNIEIVSQVIQIGD
IMAHSNDFDTVKENVEKNSVRCGDLEAAKAMEELILSKKQEGDSIGGIVETVAVGVPAGLGEPVFERLDGDLARILMNIN
AVKGVEIGFGFDVATSCASEINDEYYIEDNKIYTSTNSSGGIIGGISNGMPIISRIAVKPTPSISKCQKSVNLEKMEAED
ITIQGRHDPCICPRATVVAQSSVAIVLADHMIRSGYIHPSNLEI
>Mature_363_residues
ANTIGKMFSVTSFGSSHGKAVGAVIDGCPANLELNTEDIQKELDKRKPGTSGVTTPRKEEDKVQILSGIFEGKTDGTPIT
GVVYNNNQHSKDYSMFKNTPRPSHGDYGWMSKYGNYDYNGGGRGSGRITIGHVIAGAIAKKLLKTKNIEIVSQVIQIGDI
MAHSNDFDTVKENVEKNSVRCGDLEAAKAMEELILSKKQEGDSIGGIVETVAVGVPAGLGEPVFERLDGDLARILMNINA
VKGVEIGFGFDVATSCASEINDEYYIEDNKIYTSTNSSGGIIGGISNGMPIISRIAVKPTPSISKCQKSVNLEKMEAEDI
TIQGRHDPCICPRATVVAQSSVAIVLADHMIRSGYIHPSNLEI

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=353, Percent_Identity=50.4249291784703, Blast_Score=306, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6321290, Length=363, Percent_Identity=42.1487603305785, Blast_Score=278, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_METS3 (A5UNA1)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001274047.1
- ProteinModelPortal:   A5UNA1
- SMR:   A5UNA1
- STRING:   A5UNA1
- GeneID:   5216657
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_1474
- eggNOG:   arNOG04618
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_A
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39012; Mature: 38880

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTIGKMFSVTSFGSSHGKAVGAVIDGCPANLELNTEDIQKELDKRKPGTSGVTTPRKE
CCCHHHHHHHHHCCCCCCCCEEEHEECCCCCCCEECHHHHHHHHHHCCCCCCCCCCCCCC
EDKVQILSGIFEGKTDGTPITGVVYNNNQHSKDYSMFKNTPRPSHGDYGWMSKYGNYDYN
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCHHHHCCCCCCC
GGGRGSGRITIGHVIAGAIAKKLLKTKNIEIVSQVIQIGDIMAHSNDFDTVKENVEKNSV
CCCCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
RCGDLEAAKAMEELILSKKQEGDSIGGIVETVAVGVPAGLGEPVFERLDGDLARILMNIN
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHH
AVKGVEIGFGFDVATSCASEINDEYYIEDNKIYTSTNSSGGIIGGISNGMPIISRIAVKP
HHCCEEEECCHHHHHHHHHHCCCCEEEECCEEEEECCCCCCEEEECCCCCHHHHHEECCC
TPSISKCQKSVNLEKMEAEDITIQGRHDPCICPRATVVAQSSVAIVLADHMIRSGYIHPS
CCCHHHHHHHCCHHHCCCCCEEEECCCCCCCCCCHHEEECCCEEEEEEHHHHHHCCCCCC
NLEI
CCCC
>Mature Secondary Structure 
ANTIGKMFSVTSFGSSHGKAVGAVIDGCPANLELNTEDIQKELDKRKPGTSGVTTPRKE
CCHHHHHHHHHCCCCCCCCEEEHEECCCCCCCEECHHHHHHHHHHCCCCCCCCCCCCCC
EDKVQILSGIFEGKTDGTPITGVVYNNNQHSKDYSMFKNTPRPSHGDYGWMSKYGNYDYN
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCHHHHCCCCCCC
GGGRGSGRITIGHVIAGAIAKKLLKTKNIEIVSQVIQIGDIMAHSNDFDTVKENVEKNSV
CCCCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
RCGDLEAAKAMEELILSKKQEGDSIGGIVETVAVGVPAGLGEPVFERLDGDLARILMNIN
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHH
AVKGVEIGFGFDVATSCASEINDEYYIEDNKIYTSTNSSGGIIGGISNGMPIISRIAVKP
HHCCEEEECCHHHHHHHHHHCCCCEEEECCEEEEECCCCCCEEEECCCCCHHHHHEECCC
TPSISKCQKSVNLEKMEAEDITIQGRHDPCICPRATVVAQSSVAIVLADHMIRSGYIHPS
CCCHHHHHHHCCHHHCCCCCEEEECCCCCCCCCCHHEEECCCEEEEEEHHHHHHCCCCCC
NLEI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA