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The map label for this gene is 148643233

Identifier: 148643233

GI number: 148643233

Start: 1155719

End: 1156444

Strand: Reverse

Name: 148643233

Synonym: Msm_1173

Alternate gene names: NA

Gene position: 1156444-1155719 (Counterclockwise)

Preceding gene: 148643234

Following gene: 148643230

Centisome position: 62.4

GC content: 34.3

Gene sequence:

>726_bases
ATGATTTTAGATGAACGTGGTAAGAAGTATCTTCTTAAAGAAGACTGTGAATTTCAAAGTGATTTAGGTATTGTTACTAA
AGAACAGATAGCTAATTGTGAAATAGGTGATGAGCTTAAAAGTCACTTGGACCACACATTTAAAATTGTTAAACCTACTG
TTAATGATTTCATTGATTTAATGGATAGACGTTGTTCAATATTAGTTAAAAAAGATATTGGAACTGTGCTGGCTTACACG
GGTTTAGGTTCAGGAGACAGAGTTGTTGATTCTGGAACTGGTGCTGGAGCTATTGCACTGAATTTCGGAAATGTGGTGGG
CGGCACCGGTAAGGTTTATACCTATGAAATAAGGGAAGATTTTGCTAAAGTAGCTCAAAAAAACATTGAAACTTTTGGAA
TCAATAATATTGAAGTTAAAAACAAAGATATTAAGGAAGGAATCGATGAACAAAACATTGATCTGGTCTTTTTAGATTTG
CCAAAGCCTTTTGAAATTTTTGAAGATGTTTATGAGTCTTTAAAAGTAGGCGGATGGTTAGCAGTTTATGCACCATATAT
TGATCAGGCAGAAATAGCTTATAGGGTAGCTAAAAAACTTAATTTTTACAATATCGAAATATTGGAAACATTGGAAAGAG
GTCTGGAAGTTAGACCTCAGGGAGTCAGACCAAAAACCCGTATGGTTGGTCATACTGGGTATTTAGTCTTTGCCCGTAAA
TTATAA

Upstream 100 bases:

>100_bases
TACATCTAATAAAATTATGGAATTGTTCTCAACACATCCGGATTCATTAAAAAGAGTAAAAAGACTTTCTGAATTAGAAA
ATTAGGTGATTAATTTGAAA

Downstream 100 bases:

>100_bases
AAATATTAAAGGGTAATTGAACTCTTTAATTAATCTTTTTCTAAAACCGTCATATGGTATCATTTATTTTAGGTTAATAA
CAGTTTGAATGATTAATAAT

Product: tRNA(1-methyladenosine) methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MILDERGKKYLLKEDCEFQSDLGIVTKEQIANCEIGDELKSHLDHTFKIVKPTVNDFIDLMDRRCSILVKKDIGTVLAYT
GLGSGDRVVDSGTGAGAIALNFGNVVGGTGKVYTYEIREDFAKVAQKNIETFGINNIEVKNKDIKEGIDEQNIDLVFLDL
PKPFEIFEDVYESLKVGGWLAVYAPYIDQAEIAYRVAKKLNFYNIEILETLERGLEVRPQGVRPKTRMVGHTGYLVFARK
L

Sequences:

>Translated_241_residues
MILDERGKKYLLKEDCEFQSDLGIVTKEQIANCEIGDELKSHLDHTFKIVKPTVNDFIDLMDRRCSILVKKDIGTVLAYT
GLGSGDRVVDSGTGAGAIALNFGNVVGGTGKVYTYEIREDFAKVAQKNIETFGINNIEVKNKDIKEGIDEQNIDLVFLDL
PKPFEIFEDVYESLKVGGWLAVYAPYIDQAEIAYRVAKKLNFYNIEILETLERGLEVRPQGVRPKTRMVGHTGYLVFARK
L
>Mature_241_residues
MILDERGKKYLLKEDCEFQSDLGIVTKEQIANCEIGDELKSHLDHTFKIVKPTVNDFIDLMDRRCSILVKKDIGTVLAYT
GLGSGDRVVDSGTGAGAIALNFGNVVGGTGKVYTYEIREDFAKVAQKNIETFGINNIEVKNKDIKEGIDEQNIDLVFLDL
PKPFEIFEDVYESLKVGGWLAVYAPYIDQAEIAYRVAKKLNFYNIEILETLERGLEVRPQGVRPKTRMVGHTGYLVFARK
L

Specific function: Unknown

COG id: COG2519

COG function: function code J; tRNA(1-methyladenosine) methyltransferase and related methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TRM61 family [H]

Homologues:

Organism=Homo sapiens, GI222831587, Length=186, Percent_Identity=29.5698924731183, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI123173772, Length=219, Percent_Identity=26.9406392694064, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17509459, Length=210, Percent_Identity=25.2380952380952, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24650257, Length=204, Percent_Identity=28.4313725490196, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014816 [H]

Pfam domain/function: PF08704 GCD14 [H]

EC number: =2.1.1.36 [H]

Molecular weight: Translated: 27102; Mature: 27102

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILDERGKKYLLKEDCEFQSDLGIVTKEQIANCEIGDELKSHLDHTFKIVKPTVNDFIDL
CCCCCCCCEEEHHCCCCCCCCCCCEEHHHHCCCCCHHHHHHHHHHHEEEECCCHHHHHHH
MDRRCSILVKKDIGTVLAYTGLGSGDRVVDSGTGAGAIALNFGNVVGGTGKVYTYEIRED
HHHHHHEEEECCCCEEEEECCCCCCCEEEECCCCCCEEEEECCCEECCCCCEEEEHHHHH
FAKVAQKNIETFGINNIEVKNKDIKEGIDEQNIDLVFLDLPKPFEIFEDVYESLKVGGWL
HHHHHHHCCHHCCCCCEEECCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEE
AVYAPYIDQAEIAYRVAKKLNFYNIEILETLERGLEVRPQGVRPKTRMVGHTGYLVFARK
EEECCCCCHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCCCCCHHHEECCCEEEEEEEC
L
C
>Mature Secondary Structure
MILDERGKKYLLKEDCEFQSDLGIVTKEQIANCEIGDELKSHLDHTFKIVKPTVNDFIDL
CCCCCCCCEEEHHCCCCCCCCCCCEEHHHHCCCCCHHHHHHHHHHHEEEECCCHHHHHHH
MDRRCSILVKKDIGTVLAYTGLGSGDRVVDSGTGAGAIALNFGNVVGGTGKVYTYEIRED
HHHHHHEEEECCCCEEEEECCCCCCCEEEECCCCCCEEEEECCCEECCCCCEEEEHHHHH
FAKVAQKNIETFGINNIEVKNKDIKEGIDEQNIDLVFLDLPKPFEIFEDVYESLKVGGWL
HHHHHHHCCHHCCCCCEEECCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEE
AVYAPYIDQAEIAYRVAKKLNFYNIEILETLERGLEVRPQGVRPKTRMVGHTGYLVFARK
EEECCCCCHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCCCCCHHHEECCCEEEEEEEC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]