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The map label for this gene is htpX [H]

Identifier: 148643234

GI number: 148643234

Start: 1156460

End: 1157419

Strand: Reverse

Name: htpX [H]

Synonym: Msm_1174

Alternate gene names: 148643234

Gene position: 1157419-1156460 (Counterclockwise)

Preceding gene: 148643235

Following gene: 148643233

Centisome position: 62.46

GC content: 32.92

Gene sequence:

>960_bases
ATGAAAGGTACATGGAAACTTAAAGTAAGAATGGCACTTACTATGATTATATTGTTCACTATTGTGTATTTCCTTGTTAT
ATTGGCTGGTAGCTATTTGGGAATTGGTGGACCATCATTTTACTTAATTATAAGTCTTTGTATTGTAGCTGCACAGTACT
GGTTTGGCCCTACATTAGTTAAACATTCTATGAATGTAAGGCCGTTGTCTGAAAGTGAAGCTCCAAATATTCATCAGATG
GTTGAAGAACTTGCATGTGAAGCAGGTGTTCCAAAACCACAGATCGAACTTTCTGAAATAAATGTTCCGAATGCATTTGC
ATATGGCAGGTCTAAAAGAAGTGGACATATAGCTATTACTCGTCCAATTTTAGGTTTGCTTGATAGAAATGAGTTAAAAG
CAGTTTTAGGTCATGAAATGGGTCATATTAAACATAATGACATGATTGTTACAGCTATTGTAAGCTTAGTTCCAATGATT
TGTTATTATATTGCATTATCATTTATGTTTTCACGCAACAACGAAAACAATGCAGGTATTATTATCGGAATATTGGGTTA
TGTATTCTATCTTATAGGACAATTGCTTGTATTATTTATATCAAGAACAAGAGAATATTATGCAGATGAAGCTAGTGTGG
AATATGGAAATCGTCCAGCAGATTTAGTTTCAGCTCTTTATAAATTATCTTACGGAGCTGCAAGATGTGACGATGAAACA
ATTAAGGATGTAAATACTGTTCGTGCATTTTTTGTTAATGATGTAGATAATGCTACAAGAGATTTAAATGACTTCAGACA
AATAGATTTCGATGGTGACGGATCCATTTCCGAAGAAGAGTTAAGGGAACTTAGTCAAAGAAATGTTGATGTTTCTACAT
CTAATAAAATTATGGAATTGTTCTCAACACATCCGGATTCATTAAAAAGAGTAAAAAGACTTTCTGAATTAGAAAATTAG

Upstream 100 bases:

>100_bases
TATTGGTCTTCAAGCGGACCAATTTCTGAAGAAAGAATAGGTTAATAAATAGGTAGTTATAAAATATATAAAAAATTTAT
AAAATTATGAGGCGTATTAA

Downstream 100 bases:

>100_bases
GTGATTAATTTGAAAATGATTTTAGATGAACGTGGTAAGAAGTATCTTCTTAAAGAAGACTGTGAATTTCAAAGTGATTT
AGGTATTGTTACTAAAGAAC

Product: heat shock protein HtpX (Zn-dependent)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MKGTWKLKVRMALTMIILFTIVYFLVILAGSYLGIGGPSFYLIISLCIVAAQYWFGPTLVKHSMNVRPLSESEAPNIHQM
VEELACEAGVPKPQIELSEINVPNAFAYGRSKRSGHIAITRPILGLLDRNELKAVLGHEMGHIKHNDMIVTAIVSLVPMI
CYYIALSFMFSRNNENNAGIIIGILGYVFYLIGQLLVLFISRTREYYADEASVEYGNRPADLVSALYKLSYGAARCDDET
IKDVNTVRAFFVNDVDNATRDLNDFRQIDFDGDGSISEEELRELSQRNVDVSTSNKIMELFSTHPDSLKRVKRLSELEN

Sequences:

>Translated_319_residues
MKGTWKLKVRMALTMIILFTIVYFLVILAGSYLGIGGPSFYLIISLCIVAAQYWFGPTLVKHSMNVRPLSESEAPNIHQM
VEELACEAGVPKPQIELSEINVPNAFAYGRSKRSGHIAITRPILGLLDRNELKAVLGHEMGHIKHNDMIVTAIVSLVPMI
CYYIALSFMFSRNNENNAGIIIGILGYVFYLIGQLLVLFISRTREYYADEASVEYGNRPADLVSALYKLSYGAARCDDET
IKDVNTVRAFFVNDVDNATRDLNDFRQIDFDGDGSISEEELRELSQRNVDVSTSNKIMELFSTHPDSLKRVKRLSELEN
>Mature_319_residues
MKGTWKLKVRMALTMIILFTIVYFLVILAGSYLGIGGPSFYLIISLCIVAAQYWFGPTLVKHSMNVRPLSESEAPNIHQM
VEELACEAGVPKPQIELSEINVPNAFAYGRSKRSGHIAITRPILGLLDRNELKAVLGHEMGHIKHNDMIVTAIVSLVPMI
CYYIALSFMFSRNNENNAGIIIGILGYVFYLIGQLLVLFISRTREYYADEASVEYGNRPADLVSALYKLSYGAARCDDET
IKDVNTVRAFFVNDVDNATRDLNDFRQIDFDGDGSISEEELRELSQRNVDVSTSNKIMELFSTHPDSLKRVKRLSELEN

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=213, Percent_Identity=24.4131455399061, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 35858; Mature: 35858

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00018 EF_HAND_1 ; PS50222 EF_HAND_2 L=RR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTWKLKVRMALTMIILFTIVYFLVILAGSYLGIGGPSFYLIISLCIVAAQYWFGPTLV
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
KHSMNVRPLSESEAPNIHQMVEELACEAGVPKPQIELSEINVPNAFAYGRSKRSGHIAIT
HHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHCCCCCHHHCCCCCCCCCEEEH
RPILGLLDRNELKAVLGHEMGHIKHNDMIVTAIVSLVPMICYYIALSFMFSRNNENNAGI
HHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IIGILGYVFYLIGQLLVLFISRTREYYADEASVEYGNRPADLVSALYKLSYGAARCDDET
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
IKDVNTVRAFFVNDVDNATRDLNDFRQIDFDGDGSISEEELRELSQRNVDVSTSNKIMEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
FSTHPDSLKRVKRLSELEN
HHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGTWKLKVRMALTMIILFTIVYFLVILAGSYLGIGGPSFYLIISLCIVAAQYWFGPTLV
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
KHSMNVRPLSESEAPNIHQMVEELACEAGVPKPQIELSEINVPNAFAYGRSKRSGHIAIT
HHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHCCCCCHHHCCCCCCCCCEEEH
RPILGLLDRNELKAVLGHEMGHIKHNDMIVTAIVSLVPMICYYIALSFMFSRNNENNAGI
HHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IIGILGYVFYLIGQLLVLFISRTREYYADEASVEYGNRPADLVSALYKLSYGAARCDDET
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
IKDVNTVRAFFVNDVDNATRDLNDFRQIDFDGDGSISEEELRELSQRNVDVSTSNKIMEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
FSTHPDSLKRVKRLSELEN
HHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]