Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 148642890

GI number: 148642890

Start: 788584

End: 789405

Strand: Reverse

Name: dapB

Synonym: Msm_0830

Alternate gene names: 148642890

Gene position: 789405-788584 (Counterclockwise)

Preceding gene: 148642891

Following gene: 148642889

Centisome position: 42.6

GC content: 36.01

Gene sequence:

>822_bases
ATGATTAAAGTAGCAGTCACCGGAGCAGCTGGAAGAATGGGCTCCGGTATTATTAGAAAAATAACACAGCAAGATGATAT
GGAAGTAGTAGCAGCTATTGAAATTCCTAATTCTCCATTAGCTGGAGTGGATGCAGGTATTCAAGCAGGTGCTGGTGAAC
TTGGAGTTAAAATAGTCGGTGCTGAAAAATTAGAAGAAACATTAAAAGAATCTAAAGCAGATGTTTTAGTTGATTTCACC
ATAGCTCATGCAGCAGTTGAAACAGTTAAAAAAGCTACAGCATGTGGTGTTAATGTTGTAGTAGGTACTACTGGTTTTAC
TGATGAACAAATGGCTGAAAATATTAAAAATGTAAAAGACAATGATGTAAAAGCAGTTATTTCATCTAACATGTCTATTG
GGGTAAATGTATTTTTCAATACTTTGAAAAAATTAACTCCTATCTTAAATGATTTTGACATTGAAATTATTGAAGCACAT
CACAATCAGAAAAAAGATGCTCCATCTGGAACTGCAATGACTGCATTTGAAGTAATAGCTAATGAACTTGACCGTGACCC
TGAAGAAGTAGGAGTTTATGGAAGACAAGGAATGGTTGGTAAAAGAACCAAAGAGGAAATAGGTTTACATGCTATTCGTG
GTGGAGACATTGTTGGAGACCACACTGTAATGTTTATCGGAGATGGTGAAAGAATAGAATTCACTCACCGTGCTCACACC
AGGGAAGTTTTTATTGCAGGTGTAATTAGAGCTATTCGATACATTCCAGATGCGGAATCAGGTATTGTAAGTAGTATGAA
TGATGTTTTAGGATTAGAATAG

Upstream 100 bases:

>100_bases
GGACCTCTCAGGGCACCGTTAACAGATATGAAAGATGAAAATGTTGAAATTCTCAAAAATGCTTTAAAAGAAGCAGATTT
AATTTAAGTTGGTAATATTT

Downstream 100 bases:

>100_bases
GTGTTATCTATGGTGAATGTTGGTATACTTGGTGCAACTGGAATGGTTGGTCAAAGATTTATCCAATTACTTGATAACCA
TCCAGATTTTGAAATTACAG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MIKVAVTGAAGRMGSGIIRKITQQDDMEVVAAIEIPNSPLAGVDAGIQAGAGELGVKIVGAEKLEETLKESKADVLVDFT
IAHAAVETVKKATACGVNVVVGTTGFTDEQMAENIKNVKDNDVKAVISSNMSIGVNVFFNTLKKLTPILNDFDIEIIEAH
HNQKKDAPSGTAMTAFEVIANELDRDPEEVGVYGRQGMVGKRTKEEIGLHAIRGGDIVGDHTVMFIGDGERIEFTHRAHT
REVFIAGVIRAIRYIPDAESGIVSSMNDVLGLE

Sequences:

>Translated_273_residues
MIKVAVTGAAGRMGSGIIRKITQQDDMEVVAAIEIPNSPLAGVDAGIQAGAGELGVKIVGAEKLEETLKESKADVLVDFT
IAHAAVETVKKATACGVNVVVGTTGFTDEQMAENIKNVKDNDVKAVISSNMSIGVNVFFNTLKKLTPILNDFDIEIIEAH
HNQKKDAPSGTAMTAFEVIANELDRDPEEVGVYGRQGMVGKRTKEEIGLHAIRGGDIVGDHTVMFIGDGERIEFTHRAHT
REVFIAGVIRAIRYIPDAESGIVSSMNDVLGLE
>Mature_273_residues
MIKVAVTGAAGRMGSGIIRKITQQDDMEVVAAIEIPNSPLAGVDAGIQAGAGELGVKIVGAEKLEETLKESKADVLVDFT
IAHAAVETVKKATACGVNVVVGTTGFTDEQMAENIKNVKDNDVKAVISSNMSIGVNVFFNTLKKLTPILNDFDIEIIEAH
HNQKKDAPSGTAMTAFEVIANELDRDPEEVGVYGRQGMVGKRTKEEIGLHAIRGGDIVGDHTVMFIGDGERIEFTHRAHT
REVFIAGVIRAIRYIPDAESGIVSSMNDVLGLE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=274, Percent_Identity=40.1459854014599, Blast_Score=184, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_METS3 (A5ULF7)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273403.1
- ProteinModelPortal:   A5ULF7
- SMR:   A5ULF7
- STRING:   A5ULF7
- GeneID:   5216091
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0830
- eggNOG:   arNOG05038
- HOGENOM:   HBG594002
- OMA:   FEVIANE
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29137; Mature: 29137

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVAVTGAAGRMGSGIIRKITQQDDMEVVAAIEIPNSPLAGVDAGIQAGAGELGVKIVG
CEEEEEECCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEC
AEKLEETLKESKADVLVDFTIAHAAVETVKKATACGVNVVVGTTGFTDEQMAENIKNVKD
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCC
NDVKAVISSNMSIGVNVFFNTLKKLTPILNDFDIEIIEAHHNQKKDAPSGTAMTAFEVIA
CHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHH
NELDRDPEEVGVYGRQGMVGKRTKEEIGLHAIRGGDIVGDHTVMFIGDGERIEFTHRAHT
HHHCCCHHHHCCCCCCCCCCCCCHHHHCEEEECCCCEECCCEEEEEECCCEEEEEECCCH
REVFIAGVIRAIRYIPDAESGIVSSMNDVLGLE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIKVAVTGAAGRMGSGIIRKITQQDDMEVVAAIEIPNSPLAGVDAGIQAGAGELGVKIVG
CEEEEEECCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEC
AEKLEETLKESKADVLVDFTIAHAAVETVKKATACGVNVVVGTTGFTDEQMAENIKNVKD
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCC
NDVKAVISSNMSIGVNVFFNTLKKLTPILNDFDIEIIEAHHNQKKDAPSGTAMTAFEVIA
CHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHH
NELDRDPEEVGVYGRQGMVGKRTKEEIGLHAIRGGDIVGDHTVMFIGDGERIEFTHRAHT
HHHCCCHHHHCCCCCCCCCCCCCHHHHCEEEECCCCEECCCEEEEEECCCEEEEEECCCH
REVFIAGVIRAIRYIPDAESGIVSSMNDVLGLE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA