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The map label for this gene is asd [H]

Identifier: 148642889

GI number: 148642889

Start: 787525

End: 788574

Strand: Reverse

Name: asd [H]

Synonym: Msm_0829

Alternate gene names: 148642889

Gene position: 788574-787525 (Counterclockwise)

Preceding gene: 148642890

Following gene: 148642888

Centisome position: 42.55

GC content: 34.86

Gene sequence:

>1050_bases
ATGGTGAATGTTGGTATACTTGGTGCAACTGGAATGGTTGGTCAAAGATTTATCCAATTACTTGATAACCATCCAGATTT
TGAAATTACAGCATTAGCTGCATCTTCAAGATCTGCAGGTAAAAGATATGAGGATGCTACTACATGGTATCTTGATAATG
AAATGCCTGATTCTGTTAAGGACATTATTGTAAAAGAAACTGATGCTGATGCAATGGATAATGATGTGGATATTGTATTT
TCATCTCTTCCAACAGAATTTGCAGCTAAAGTTGAAAAAGATTTTGCTCGTGATTATGTTGTTGCAAGTAATGCTAGTGC
TCACAGGATGAAAAAAAATATTCCTTTAGTTATCCCTGAAGTTAATCCGGAATATCTGGATATGATTGATGCTCAGCAAA
AGGAAAATAATTGGGATGGATTCATCGTAACCAATCCTAACTGTTCAACTATTGCTTTAACTTTGTCATTAAAACCAATT
GTTGATAATTTTAATGTAGATGCAATTAGAGTGTCAACAATGCAGGCAGTATCTGGTGCAGGTTATAATGGTGTGCCTTC
TATGGCTATTGTTGATAATCTCGTTCCTTATATTGGCAGTGAAGAGGAAAAGATGGAAAGTGAAACATTACATCTTTTAG
GTAACTATGACGGGGAAAAAGTTTCCAATGCTGATTTCAAATTAAGTGCTTCATGTCATAGGGTTCCTGTTATTGACGGC
CATACTGAAGCAGTATTTGTTGAGTTGGATGATGACTTTGATATTAATGATGTTAAAGAAAAAATGGCTAATTTCAAAGC
ATTGCCTCAAAAATTAAATTTGTTCTCTGCACCTGAAAATCCAGTAATTGTCAAAGAAGAAATTGACAGGCCTCAACCAA
GAATGGACAGAAATGCTGGTAATGGTATGTCTGTTTCTGTTGGAAGGTTAAGGAAAGACCAAGCATTTGATAACAGTTTC
AAATATGTATTGGTTGGGCATAATACAATTCGTGGAGCTGCTGGAGCTTCTGTATTAAATGCTGAATTAATCAATGATAA
AATACTCTAA

Upstream 100 bases:

>100_bases
TATTGCAGGTGTAATTAGAGCTATTCGATACATTCCAGATGCGGAATCAGGTATTGTAAGTAGTATGAATGATGTTTTAG
GATTAGAATAGGTGTTATCT

Downstream 100 bases:

>100_bases
TTTTATCCTTTTTATTTTCTTATTTTTTCTAATATTTTTTTTATTTTTCATATAATTTCTGTTTAGTTTTAATTTCAATT
TTTGGTGGTTTTTAGAGTTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MVNVGILGATGMVGQRFIQLLDNHPDFEITALAASSRSAGKRYEDATTWYLDNEMPDSVKDIIVKETDADAMDNDVDIVF
SSLPTEFAAKVEKDFARDYVVASNASAHRMKKNIPLVIPEVNPEYLDMIDAQQKENNWDGFIVTNPNCSTIALTLSLKPI
VDNFNVDAIRVSTMQAVSGAGYNGVPSMAIVDNLVPYIGSEEEKMESETLHLLGNYDGEKVSNADFKLSASCHRVPVIDG
HTEAVFVELDDDFDINDVKEKMANFKALPQKLNLFSAPENPVIVKEEIDRPQPRMDRNAGNGMSVSVGRLRKDQAFDNSF
KYVLVGHNTIRGAAGASVLNAELINDKIL

Sequences:

>Translated_349_residues
MVNVGILGATGMVGQRFIQLLDNHPDFEITALAASSRSAGKRYEDATTWYLDNEMPDSVKDIIVKETDADAMDNDVDIVF
SSLPTEFAAKVEKDFARDYVVASNASAHRMKKNIPLVIPEVNPEYLDMIDAQQKENNWDGFIVTNPNCSTIALTLSLKPI
VDNFNVDAIRVSTMQAVSGAGYNGVPSMAIVDNLVPYIGSEEEKMESETLHLLGNYDGEKVSNADFKLSASCHRVPVIDG
HTEAVFVELDDDFDINDVKEKMANFKALPQKLNLFSAPENPVIVKEEIDRPQPRMDRNAGNGMSVSVGRLRKDQAFDNSF
KYVLVGHNTIRGAAGASVLNAELINDKIL
>Mature_349_residues
MVNVGILGATGMVGQRFIQLLDNHPDFEITALAASSRSAGKRYEDATTWYLDNEMPDSVKDIIVKETDADAMDNDVDIVF
SSLPTEFAAKVEKDFARDYVVASNASAHRMKKNIPLVIPEVNPEYLDMIDAQQKENNWDGFIVTNPNCSTIALTLSLKPI
VDNFNVDAIRVSTMQAVSGAGYNGVPSMAIVDNLVPYIGSEEEKMESETLHLLGNYDGEKVSNADFKLSASCHRVPVIDG
HTEAVFVELDDDFDINDVKEKMANFKALPQKLNLFSAPENPVIVKEEIDRPQPRMDRNAGNGMSVSVGRLRKDQAFDNSF
KYVLVGHNTIRGAAGASVLNAELINDKIL

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=355, Percent_Identity=44.2253521126761, Blast_Score=291, Evalue=9e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38403; Mature: 38403

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNVGILGATGMVGQRFIQLLDNHPDFEITALAASSRSAGKRYEDATTWYLDNEMPDSVK
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCHHH
DIIVKETDADAMDNDVDIVFSSLPTEFAAKVEKDFARDYVVASNASAHRMKKNIPLVIPE
HHEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCEEEECCCHHHHHHCCCCEEEEC
VNPEYLDMIDAQQKENNWDGFIVTNPNCSTIALTLSLKPIVDNFNVDAIRVSTMQAVSGA
CCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEEEHHCCCCCCEEEEEHHHHHCCC
GYNGVPSMAIVDNLVPYIGSEEEKMESETLHLLGNYDGEKVSNADFKLSASCHRVPVIDG
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCCCCCCCEEEECCCCEEEEECC
HTEAVFVELDDDFDINDVKEKMANFKALPQKLNLFSAPENPVIVKEEIDRPQPRMDRNAG
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHCCCCCCCCCCCCCC
NGMSVSVGRLRKDQAFDNSFKYVLVGHNTIRGAAGASVLNAELINDKIL
CCCEEEHHHHHHHHCCCCCCEEEEEECCEECCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MVNVGILGATGMVGQRFIQLLDNHPDFEITALAASSRSAGKRYEDATTWYLDNEMPDSVK
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCHHH
DIIVKETDADAMDNDVDIVFSSLPTEFAAKVEKDFARDYVVASNASAHRMKKNIPLVIPE
HHEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCEEEECCCHHHHHHCCCCEEEEC
VNPEYLDMIDAQQKENNWDGFIVTNPNCSTIALTLSLKPIVDNFNVDAIRVSTMQAVSGA
CCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEEEHHCCCCCCEEEEEHHHHHCCC
GYNGVPSMAIVDNLVPYIGSEEEKMESETLHLLGNYDGEKVSNADFKLSASCHRVPVIDG
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCCCCCCCEEEECCCCEEEEECC
HTEAVFVELDDDFDINDVKEKMANFKALPQKLNLFSAPENPVIVKEEIDRPQPRMDRNAG
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHCCCCCCCCCCCCCC
NGMSVSVGRLRKDQAFDNSFKYVLVGHNTIRGAAGASVLNAELINDKIL
CCCEEEHHHHHHHHCCCCCCEEEEEECCEECCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]