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The map label for this gene is serB [C]

Identifier: 148642779

GI number: 148642779

Start: 688577

End: 690166

Strand: Reverse

Name: serB [C]

Synonym: Msm_0719

Alternate gene names: 148642779

Gene position: 690166-688577 (Counterclockwise)

Preceding gene: 148642780

Following gene: 148642778

Centisome position: 37.24

GC content: 31.82

Gene sequence:

>1590_bases
TTGATTAAACTTGTAGTATTTGACTTAGATAACGTTATTATTGATGGAGAAGCAATTGATGAGATAGGGAAATTAGCAAA
TGTTGAAGATGAAATAGCTGAAATTACTGAAAAAGCTATGCAAGGTGAAATCGACTTTGAAACTTCTATTAAAGATAGAG
TTAAACTTCTTGAAGGAACTTCCATTGAAGATATTCAAAAAGTTGCTGATGAACTTCCATTAATGAATGGTGCTGAAGAT
ACCATCGCACGTTTAAAAGAAGAAGGATTAGATGTAGCTATTATTAGTGGCAGTTTTGATGTTGTTGCACAAACCGTTAA
AGACAAACTCGGTATTGAAAATGCATACACTAATAGTTTCACTGTTGAAGACGGTAAATTGACTGGTGAAGTAACTGGAC
CTTTAGTATCTGGTTCTAAATTGGACGTATTAAAAGAACATATTGAAGGTAATGACACTTCTTTAGAAGAAGTTGTTGCA
GTTGGAGATGGAGCTAACGACATTTCCATGATCGAATCAGCAGGTATTGGAATTGCTTTCAATGCAAAAGATTCTGTTAA
AGAAAAAGCTGATGTTGTAGTAGATGAAAAAGACTTAACCAAAGTCTTAGATGAAATTATTAATCAATTATCCACTGATG
TTGTTGAAAATGACGAAACTGAACAAGTAGAAGAAGCAGAAGATGCTGAAGAATCTACTGAAGAAGCTGAAAAACCTAAA
AAAGACGGTCTTCCTGAATCTGATTTTGTTTTAGCTGACACCATGGAAGGTGTAAGAAAACAAAAAGATGAAAAAGAAGC
TGAAATAGCTAAAGTTACTGAAGAAAGAGAAGAATTCAACAGGATAGCTAAAGAACAACGTAAAATTCGTGATGAATTAA
ACGCATCATTAAAAGAAAACTTAAACAAAGCTATTGAATTCAGAAATGAACGTAACGAAATCAACAAAAAAGTTGAAGAA
GCTAAAAAAGCACGTAACGAAGCTAACAACAAAATTAGAAACTTAGAATGGTCTTCTGGTAAACGTGACAAAATTAAAAT
AGAAAATGAGATTAAAAAGATTGATAAAATCATTGAAACTCGTGTTTTAGATATTAAAAAAGAAAATCAACTTGTTAAAA
ATGCAAACGATTTAAGAAAACAGTTAATGGAAATTCATGAAGATGAATCCGTTAAAGGTGAAGCACAAGAGCTTAAAAAA
TTATCTGAAGAAGAACACGAAAAAGTTATTGACTTTTCTGAAAAAGCTCAAGCAGCTCACGAAGAAATGCTCAAATTCTT
CAGAAAAACTGATGATATCAGAACTGCAGCTGATGAAGCTCACAAAAAATTCATCGAAGCTCGTAAAAATGCTTCTGCAA
AACATGAAGAGTTCAAATCCATTTTAAGCGATATTCATGTTATCAATAAAAAATTAGGTTCCAACAGACCTAGAAAAAGA
AGATCTGCTAGTAACAAATCTTCCTCATCAAACGGTAACAAAAATCGTGAAGAAAAAGAAAGAGCTGAAGAAATCTTCGA
TAAATTCAAACACGGTGGAAAATTATCTACTGAAGAGCTCTTACTTTTACAAAAATACAATATTAATTAA

Upstream 100 bases:

>100_bases
TGTTTGTACTGGAGCTAAAACACGTAGCGACGCTAAATTAGGTGTCGAAAGAGCTTACGATAGATTAAGTGAGCTAGATT
TAATATAATTGGTGGTATGA

Downstream 100 bases:

>100_bases
GTAATTTACTGAAATTACTTTAATTTTTATTTATTTCTTTTTTTAAGGTAATATCATGTCTGATGAAGAAAAAATTGAAA
CCTGTTTTTTATGCGGCAAG

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MIKLVVFDLDNVIIDGEAIDEIGKLANVEDEIAEITEKAMQGEIDFETSIKDRVKLLEGTSIEDIQKVADELPLMNGAED
TIARLKEEGLDVAIISGSFDVVAQTVKDKLGIENAYTNSFTVEDGKLTGEVTGPLVSGSKLDVLKEHIEGNDTSLEEVVA
VGDGANDISMIESAGIGIAFNAKDSVKEKADVVVDEKDLTKVLDEIINQLSTDVVENDETEQVEEAEDAEESTEEAEKPK
KDGLPESDFVLADTMEGVRKQKDEKEAEIAKVTEEREEFNRIAKEQRKIRDELNASLKENLNKAIEFRNERNEINKKVEE
AKKARNEANNKIRNLEWSSGKRDKIKIENEIKKIDKIIETRVLDIKKENQLVKNANDLRKQLMEIHEDESVKGEAQELKK
LSEEEHEKVIDFSEKAQAAHEEMLKFFRKTDDIRTAADEAHKKFIEARKNASAKHEEFKSILSDIHVINKKLGSNRPRKR
RSASNKSSSSNGNKNREEKERAEEIFDKFKHGGKLSTEELLLLQKYNIN

Sequences:

>Translated_529_residues
MIKLVVFDLDNVIIDGEAIDEIGKLANVEDEIAEITEKAMQGEIDFETSIKDRVKLLEGTSIEDIQKVADELPLMNGAED
TIARLKEEGLDVAIISGSFDVVAQTVKDKLGIENAYTNSFTVEDGKLTGEVTGPLVSGSKLDVLKEHIEGNDTSLEEVVA
VGDGANDISMIESAGIGIAFNAKDSVKEKADVVVDEKDLTKVLDEIINQLSTDVVENDETEQVEEAEDAEESTEEAEKPK
KDGLPESDFVLADTMEGVRKQKDEKEAEIAKVTEEREEFNRIAKEQRKIRDELNASLKENLNKAIEFRNERNEINKKVEE
AKKARNEANNKIRNLEWSSGKRDKIKIENEIKKIDKIIETRVLDIKKENQLVKNANDLRKQLMEIHEDESVKGEAQELKK
LSEEEHEKVIDFSEKAQAAHEEMLKFFRKTDDIRTAADEAHKKFIEARKNASAKHEEFKSILSDIHVINKKLGSNRPRKR
RSASNKSSSSNGNKNREEKERAEEIFDKFKHGGKLSTEELLLLQKYNIN
>Mature_529_residues
MIKLVVFDLDNVIIDGEAIDEIGKLANVEDEIAEITEKAMQGEIDFETSIKDRVKLLEGTSIEDIQKVADELPLMNGAED
TIARLKEEGLDVAIISGSFDVVAQTVKDKLGIENAYTNSFTVEDGKLTGEVTGPLVSGSKLDVLKEHIEGNDTSLEEVVA
VGDGANDISMIESAGIGIAFNAKDSVKEKADVVVDEKDLTKVLDEIINQLSTDVVENDETEQVEEAEDAEESTEEAEKPK
KDGLPESDFVLADTMEGVRKQKDEKEAEIAKVTEEREEFNRIAKEQRKIRDELNASLKENLNKAIEFRNERNEINKKVEE
AKKARNEANNKIRNLEWSSGKRDKIKIENEIKKIDKIIETRVLDIKKENQLVKNANDLRKQLMEIHEDESVKGEAQELKK
LSEEEHEKVIDFSEKAQAAHEEMLKFFRKTDDIRTAADEAHKKFIEARKNASAKHEEFKSILSDIHVINKKLGSNRPRKR
RSASNKSSSSNGNKNREEKERAEEIFDKFKHGGKLSTEELLLLQKYNIN

Specific function: Unknown

COG id: COG1340

COG function: function code S; Uncharacterized archaeal coiled-coil protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=218, Percent_Identity=30.2752293577982, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1790849, Length=201, Percent_Identity=41.7910447761194, Blast_Score=157, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI115534456, Length=213, Percent_Identity=29.1079812206573, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534454, Length=213, Percent_Identity=29.1079812206573, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=217, Percent_Identity=36.405529953917, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24661601, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 59713; Mature: 59713

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLVVFDLDNVIIDGEAIDEIGKLANVEDEIAEITEKAMQGEIDFETSIKDRVKLLEGT
CEEEEEEECCCEEECCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
SIEDIQKVADELPLMNGAEDTIARLKEEGLDVAIISGSFDVVAQTVKDKLGIENAYTNSF
CHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCE
TVEDGKLTGEVTGPLVSGSKLDVLKEHIEGNDTSLEEVVAVGDGANDISMIESAGIGIAF
EEECCCEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHCCCCEEE
NAKDSVKEKADVVVDEKDLTKVLDEIINQLSTDVVENDETEQVEEAEDAEESTEEAEKPK
CCCHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCH
KDGLPESDFVLADTMEGVRKQKDEKEAEIAKVTEEREEFNRIAKEQRKIRDELNASLKEN
HCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNKAIEFRNERNEINKKVEEAKKARNEANNKIRNLEWSSGKRDKIKIENEIKKIDKIIET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVLDIKKENQLVKNANDLRKQLMEIHEDESVKGEAQELKKLSEEEHEKVIDFSEKAQAAH
HHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHH
EEMLKFFRKTDDIRTAADEAHKKFIEARKNASAKHEEFKSILSDIHVINKKLGSNRPRKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RSASNKSSSSNGNKNREEKERAEEIFDKFKHGGKLSTEELLLLQKYNIN
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MIKLVVFDLDNVIIDGEAIDEIGKLANVEDEIAEITEKAMQGEIDFETSIKDRVKLLEGT
CEEEEEEECCCEEECCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
SIEDIQKVADELPLMNGAEDTIARLKEEGLDVAIISGSFDVVAQTVKDKLGIENAYTNSF
CHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCE
TVEDGKLTGEVTGPLVSGSKLDVLKEHIEGNDTSLEEVVAVGDGANDISMIESAGIGIAF
EEECCCEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHCCCCEEE
NAKDSVKEKADVVVDEKDLTKVLDEIINQLSTDVVENDETEQVEEAEDAEESTEEAEKPK
CCCHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCH
KDGLPESDFVLADTMEGVRKQKDEKEAEIAKVTEEREEFNRIAKEQRKIRDELNASLKEN
HCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNKAIEFRNERNEINKKVEEAKKARNEANNKIRNLEWSSGKRDKIKIENEIKKIDKIIET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVLDIKKENQLVKNANDLRKQLMEIHEDESVKGEAQELKKLSEEEHEKVIDFSEKAQAAH
HHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHH
EEMLKFFRKTDDIRTAADEAHKKFIEARKNASAKHEEFKSILSDIHVINKKLGSNRPRKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RSASNKSSSSNGNKNREEKERAEEIFDKFKHGGKLSTEELLLLQKYNIN
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 11342136; 12051918 [H]