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The map label for this gene is tbp

Identifier: 148642780

GI number: 148642780

Start: 690179

End: 690724

Strand: Reverse

Name: tbp

Synonym: Msm_0720

Alternate gene names: 148642780

Gene position: 690724-690179 (Counterclockwise)

Preceding gene: 148642786

Following gene: 148642779

Centisome position: 37.27

GC content: 33.52

Gene sequence:

>546_bases
TTGACCGATGTTGATATAAAAATAGAAAACATTGTGGCTTCTGCAAGCATAGGAAAAGATATAGTTTTAACTGAAGTTTC
CGAAGCTTTAGAAGGGGTTAATTTTAATCGTGAACAGTTTCCAGGATTAGTTTTTAAACTTAAAGATCCTAAAACAGCAG
CATTAATTTTCAGCTCTGGTAAGCTTGTTTGTACTGGGGCTAAGTCTATAGATGACTCAAAGTTAGCTATTAAAAAGACT
GTTGATTTAATGAGGACTATTGATACTGAAATTCCTCATGAATTCGAAATTAAAATTCAAAACATTGTGGCTTCTGCAAA
CTTAGAATCCACATTAAATTTAGAAGCAGTAGCTTTAGAACTTGAAGATACTGAATACGAACCTGAACAATTTCCGGGTT
TAGTATACAGGTTATCTGACCCTAAAGTTGTTTTATTATTATTCGGTTCCGGTAAAGTTGTTTGTACTGGAGCTAAAACA
CGTAGCGACGCTAAATTAGGTGTCGAAAGAGCTTACGATAGATTAAGTGAGCTAGATTTAATATAA

Upstream 100 bases:

>100_bases
TAAGTTTATATACTATTTAAATAAAATATTTAATTAGTAAAAATTTAATGATTTTAAATCTTTACTGTACTCATTTTAAT
AATTAATTGGAGGTTTTAAA

Downstream 100 bases:

>100_bases
TTGGTGGTATGATTGATTAAACTTGTAGTATTTGACTTAGATAACGTTATTATTGATGGAGAAGCAATTGATGAGATAGG
GAAATTAGCAAATGTTGAAG

Product: transcription factor

Products: NA

Alternate protein names: Box A-binding protein; BAP; TATA sequence-binding protein; TBP; TATA-box factor

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MTDVDIKIENIVASASIGKDIVLTEVSEALEGVNFNREQFPGLVFKLKDPKTAALIFSSGKLVCTGAKSIDDSKLAIKKT
VDLMRTIDTEIPHEFEIKIQNIVASANLESTLNLEAVALELEDTEYEPEQFPGLVYRLSDPKVVLLLFGSGKVVCTGAKT
RSDAKLGVERAYDRLSELDLI

Sequences:

>Translated_181_residues
MTDVDIKIENIVASASIGKDIVLTEVSEALEGVNFNREQFPGLVFKLKDPKTAALIFSSGKLVCTGAKSIDDSKLAIKKT
VDLMRTIDTEIPHEFEIKIQNIVASANLESTLNLEAVALELEDTEYEPEQFPGLVYRLSDPKVVLLLFGSGKVVCTGAKT
RSDAKLGVERAYDRLSELDLI
>Mature_180_residues
TDVDIKIENIVASASIGKDIVLTEVSEALEGVNFNREQFPGLVFKLKDPKTAALIFSSGKLVCTGAKSIDDSKLAIKKTV
DLMRTIDTEIPHEFEIKIQNIVASANLESTLNLEAVALELEDTEYEPEQFPGLVYRLSDPKVVLLLFGSGKVVCTGAKTR
SDAKLGVERAYDRLSELDLI

Specific function: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation

COG id: COG2101

COG function: function code K; TATA-box binding protein (TBP), component of TFIID and TFIIIB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TBP family

Homologues:

Organism=Homo sapiens, GI285026520, Length=171, Percent_Identity=39.1812865497076, Blast_Score=132, Evalue=1e-31,
Organism=Homo sapiens, GI4507379, Length=171, Percent_Identity=39.1812865497076, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI39930602, Length=168, Percent_Identity=39.2857142857143, Blast_Score=130, Evalue=5e-31,
Organism=Homo sapiens, GI4759234, Length=171, Percent_Identity=28.6549707602339, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555358, Length=158, Percent_Identity=39.873417721519, Blast_Score=127, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI193202769, Length=166, Percent_Identity=28.3132530120482, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17509361, Length=166, Percent_Identity=28.3132530120482, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320996, Length=173, Percent_Identity=42.7745664739884, Blast_Score=135, Evalue=5e-33,
Organism=Drosophila melanogaster, GI17647997, Length=171, Percent_Identity=39.1812865497076, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17136834, Length=161, Percent_Identity=36.0248447204969, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281360601, Length=161, Percent_Identity=32.9192546583851, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI161077628, Length=161, Percent_Identity=32.9192546583851, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TBP_METS3 (A5UL47)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273293.1
- ProteinModelPortal:   A5UL47
- SMR:   A5UL47
- STRING:   A5UL47
- GeneID:   5217020
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0720
- eggNOG:   arNOG09331
- HOGENOM:   HBG499930
- OMA:   FGDIREL
- ProtClustDB:   PRK00394
- HAMAP:   MF_00408
- InterPro:   IPR012295
- InterPro:   IPR000814
- InterPro:   IPR012294
- Gene3D:   G3DSA:3.30.310.10
- PANTHER:   PTHR10126
- PRINTS:   PR00686

Pfam domain/function: PF00352 TBP; SSF55945 TFIID_C/glycos_N

EC number: NA

Molecular weight: Translated: 19816; Mature: 19685

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00351 TFIID

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVDIKIENIVASASIGKDIVLTEVSEALEGVNFNREQFPGLVFKLKDPKTAALIFSSG
CCCCEEEEEHEEEECCCCCCEEHHHHHHHHHCCCCCHHHCCCEEEEECCCCEEEEEEECC
KLVCTGAKSIDDSKLAIKKTVDLMRTIDTEIPHEFEIKIQNIVASANLESTLNLEAVALE
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCEEEEEEE
LEDTEYEPEQFPGLVYRLSDPKVVLLLFGSGKVVCTGAKTRSDAKLGVERAYDRLSELDL
EECCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHCCC
I
C
>Mature Secondary Structure 
TDVDIKIENIVASASIGKDIVLTEVSEALEGVNFNREQFPGLVFKLKDPKTAALIFSSG
CCCEEEEEHEEEECCCCCCEEHHHHHHHHHCCCCCHHHCCCEEEEECCCCEEEEEEECC
KLVCTGAKSIDDSKLAIKKTVDLMRTIDTEIPHEFEIKIQNIVASANLESTLNLEAVALE
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCEEEEEEE
LEDTEYEPEQFPGLVYRLSDPKVVLLLFGSGKVVCTGAKTRSDAKLGVERAYDRLSELDL
EECCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA