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The map label for this gene is pfdA

Identifier: 148642762

GI number: 148642762

Start: 676439

End: 676879

Strand: Reverse

Name: pfdA

Synonym: Msm_0702

Alternate gene names: 148642762

Gene position: 676879-676439 (Counterclockwise)

Preceding gene: 148642763

Following gene: 148642761

Centisome position: 36.53

GC content: 35.83

Gene sequence:

>441_bases
ATGGAAGGTCAGCAAAAATTTAATCAATTACTTAATGAAATAAATGTATACAAACAGCAAGGAGACTTAATTCAGCAACA
AATTGAATTAGTCAGAGCTTCCATTGCTGAAGTTGATGCATTAACCAACACTTTGGATGATTTGGAAGGTAAAGATTCTG
TTGAAGCTTTCGTACCTGTAGGTGCTGGTTCTTTCATTAAAGGTGAACTTAAAAACACCGATGAAGTTATTGTAAGTATT
GGTTCTGGAATAGCTGTTAAAAAAGATGTTGACGGAGCAAGAGAAACTATTGCAAGACAGAAAAAAGATCTTGAAGACAG
TTTAGATAAAATGTTAGCTAATATGCAACAGGTGTCTGACATTATCGGATCTTTATCTGCTCAGGCAGAACAGTTAGCTG
CTGTTGCTCAAGGAAACATGTCAGCTACCGGATTAAACTAG

Upstream 100 bases:

>100_bases
GGTTTAAACAGAAACCAAATTTCTATTAAAGATATTGCTGAAATCGCACCTGAAGATGTTGTAGACCCAATTTTAAAAGA
AATTTTATAAGGGTGTTACT

Downstream 100 bases:

>100_bases
ATATAACTTCCTTTTTTTACTTTTTTTATTTAATTTATTTTTCCATATTTTGCTTATTTTTTAAATATTATAAAAAACAT
ATTATTTTCTAATTAAACCA

Product: prefoldin subunit alpha

Products: NA

Alternate protein names: GimC subunit alpha

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MEGQQKFNQLLNEINVYKQQGDLIQQQIELVRASIAEVDALTNTLDDLEGKDSVEAFVPVGAGSFIKGELKNTDEVIVSI
GSGIAVKKDVDGARETIARQKKDLEDSLDKMLANMQQVSDIIGSLSAQAEQLAAVAQGNMSATGLN

Sequences:

>Translated_146_residues
MEGQQKFNQLLNEINVYKQQGDLIQQQIELVRASIAEVDALTNTLDDLEGKDSVEAFVPVGAGSFIKGELKNTDEVIVSI
GSGIAVKKDVDGARETIARQKKDLEDSLDKMLANMQQVSDIIGSLSAQAEQLAAVAQGNMSATGLN
>Mature_146_residues
MEGQQKFNQLLNEINVYKQQGDLIQQQIELVRASIAEVDALTNTLDDLEGKDSVEAFVPVGAGSFIKGELKNTDEVIVSI
GSGIAVKKDVDGARETIARQKKDLEDSLDKMLANMQQVSDIIGSLSAQAEQLAAVAQGNMSATGLN

Specific function: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding

COG id: COG1730

COG function: function code O; Predicted prefoldin, molecular chaperone implicated in de novo protein folding

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prefoldin alpha subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PFDA_METS3 (A5UL29)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273275.1
- ProteinModelPortal:   A5UL29
- SMR:   A5UL29
- STRING:   A5UL29
- GeneID:   5217271
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0702
- eggNOG:   arNOG11546
- HOGENOM:   HBG551847
- OMA:   HANIADV
- ProtClustDB:   PRK03947
- HAMAP:   MF_00308
- InterPro:   IPR011599
- InterPro:   IPR009053
- InterPro:   IPR004127
- TIGRFAMs:   TIGR00293

Pfam domain/function: PF02996 Prefoldin; SSF46579 Prefoldin

EC number: NA

Molecular weight: Translated: 15649; Mature: 15649

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGQQKFNQLLNEINVYKQQGDLIQQQIELVRASIAEVDALTNTLDDLEGKDSVEAFVPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
GAGSFIKGELKNTDEVIVSIGSGIAVKKDVDGARETIARQKKDLEDSLDKMLANMQQVSD
CCCCHHHCCCCCHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGSLSAQAEQLAAVAQGNMSATGLN
HHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEGQQKFNQLLNEINVYKQQGDLIQQQIELVRASIAEVDALTNTLDDLEGKDSVEAFVPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
GAGSFIKGELKNTDEVIVSIGSGIAVKKDVDGARETIARQKKDLEDSLDKMLANMQQVSD
CCCCHHHCCCCCHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGSLSAQAEQLAAVAQGNMSATGLN
HHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA