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The map label for this gene is glmM [H]

Identifier: 148642716

GI number: 148642716

Start: 636593

End: 637966

Strand: Reverse

Name: glmM [H]

Synonym: Msm_0656

Alternate gene names: 148642716

Gene position: 637966-636593 (Counterclockwise)

Preceding gene: 148642717

Following gene: 148642715

Centisome position: 34.43

GC content: 36.61

Gene sequence:

>1374_bases
ATGCTCATAAGTTTGGAGCTTAAAAGAGTTGATTCAATGGCTGTTAAAAAACTGTTCGGAACTTCTGGAATTCGGGGGAA
AATAAATTCTGAAGTTACATGTGAACTTGCATTAAATGTCGGTAAATCATTAGCTTGTTATTTGGGTAATGAGGGAACGG
TAGTTTTAGGTTATGATACAAGAACTACTAATGTGATGCTTGACCAGGCTATTTGTGCAGGTTTGCTTGAAAGCGGAGTA
GATGTAATTAAAATAGGAATGGTTCCAACTCCTTTGGTAGGTTATGCTACTGATAAATTAGGTGCTGATGCTGGAGTAAT
GCTGACTGCATCACATAATCCTTCACAGTACAATGGAATTAAAATTTGGAATGCTAACGGAATGGCATACACTTCAGCTC
AGGAAGCTAAAATTGAAGAAATCTACTCAAATGAATCTTACACTTCAGTAAGCTGGGATAAAGTAGGTAGCTTAAGAGTT
AATGAGGAAATTAAAGGAAGATATATTGATGATCTGGTAGGTATGGTAAATATTAAGCCAGGTTTAAAGGTTGTCATTGA
TTGTGCTTCAGGGGCAGGAAGTGAAATATCTCCTTTGGTATTTAGAAAAGCGGGCTGTGAGGTAACAACTCTTAATTCTC
AGCCGGACGGTTTTTTCCCAGGAAGAAATCCTGAACCGAATGCAGAAAACCTGCAAAATCTGATGAAAACTGTAGTAGCC
ATTGGTGCAGACCTTGGAATTGCACACGACGGAGATGCAGACAGAATGATTACAATTGATGAAAATGGTGATATTTCCCC
ATTCGACTCTTTACTTGCATTAATGTCTAAAGAATTTGACGGAGACATAGTCACTACTGTAGATGCAGGTTTATGTATGG
ATGAATCTGTAAAAGGTAATGTTTTAAGAACTAAAGTCGGAGATGTAAATGTAGCTGAAGTCATAATAGAAAAAGATGCT
GCATTTGGAGGGGAACCTTCCGGAACCTGGCTGCATCCTGATTTTTGTATGTGTCCTGACGGCATACTTTCAGGTTTAAG
GATGGCTGAACTTGTATCAAACAAAGGCAAATTGTCCGAATTGCTCTTAGAGATTCCGTCTTACCCAAATATTCGTGAAA
AAATAATCTGTTCTAAAGAAGCCAAAACAGCCGTTATGGAAAATATGGAAGATTTATTAAAAGACAGTTTTGATGATATT
AAGGAAATTAATTCTATTGACGGAGTCAGATTAACTTTCAATGATGATAGCTGGGTTTTAGTAAGGCCTTCAGGAACTGA
AGATTATATTAGAATAACTTTAGAGTCTAAAGACAGCACAAAAGCTCAAGCCATTAAAGAAACATGTGTTAAAATCATAA
AAGAAAATATTTAA

Upstream 100 bases:

>100_bases
GATGATGTTTGTGAATACTCTGAAGTAGCTGTTGCAAAAGGAGGGCTTTGCAGAATTAGAGGAGCAGACGTTATGAACAT
CATGATGGATTTAATGAACT

Downstream 100 bases:

>100_bases
ATTCTTTTTCATGCAGCGGATTACTGCATGTTTTTTTTAATCTTCTTTTTTTCAATTAAAAAAATTAATTAATAAGTATA
AACTTAACATATTATAATAG

Product: phosphomannomutase, ManB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MLISLELKRVDSMAVKKLFGTSGIRGKINSEVTCELALNVGKSLACYLGNEGTVVLGYDTRTTNVMLDQAICAGLLESGV
DVIKIGMVPTPLVGYATDKLGADAGVMLTASHNPSQYNGIKIWNANGMAYTSAQEAKIEEIYSNESYTSVSWDKVGSLRV
NEEIKGRYIDDLVGMVNIKPGLKVVIDCASGAGSEISPLVFRKAGCEVTTLNSQPDGFFPGRNPEPNAENLQNLMKTVVA
IGADLGIAHDGDADRMITIDENGDISPFDSLLALMSKEFDGDIVTTVDAGLCMDESVKGNVLRTKVGDVNVAEVIIEKDA
AFGGEPSGTWLHPDFCMCPDGILSGLRMAELVSNKGKLSELLLEIPSYPNIREKIICSKEAKTAVMENMEDLLKDSFDDI
KEINSIDGVRLTFNDDSWVLVRPSGTEDYIRITLESKDSTKAQAIKETCVKIIKENI

Sequences:

>Translated_457_residues
MLISLELKRVDSMAVKKLFGTSGIRGKINSEVTCELALNVGKSLACYLGNEGTVVLGYDTRTTNVMLDQAICAGLLESGV
DVIKIGMVPTPLVGYATDKLGADAGVMLTASHNPSQYNGIKIWNANGMAYTSAQEAKIEEIYSNESYTSVSWDKVGSLRV
NEEIKGRYIDDLVGMVNIKPGLKVVIDCASGAGSEISPLVFRKAGCEVTTLNSQPDGFFPGRNPEPNAENLQNLMKTVVA
IGADLGIAHDGDADRMITIDENGDISPFDSLLALMSKEFDGDIVTTVDAGLCMDESVKGNVLRTKVGDVNVAEVIIEKDA
AFGGEPSGTWLHPDFCMCPDGILSGLRMAELVSNKGKLSELLLEIPSYPNIREKIICSKEAKTAVMENMEDLLKDSFDDI
KEINSIDGVRLTFNDDSWVLVRPSGTEDYIRITLESKDSTKAQAIKETCVKIIKENI
>Mature_457_residues
MLISLELKRVDSMAVKKLFGTSGIRGKINSEVTCELALNVGKSLACYLGNEGTVVLGYDTRTTNVMLDQAICAGLLESGV
DVIKIGMVPTPLVGYATDKLGADAGVMLTASHNPSQYNGIKIWNANGMAYTSAQEAKIEEIYSNESYTSVSWDKVGSLRV
NEEIKGRYIDDLVGMVNIKPGLKVVIDCASGAGSEISPLVFRKAGCEVTTLNSQPDGFFPGRNPEPNAENLQNLMKTVVA
IGADLGIAHDGDADRMITIDENGDISPFDSLLALMSKEFDGDIVTTVDAGLCMDESVKGNVLRTKVGDVNVAEVIIEKDA
AFGGEPSGTWLHPDFCMCPDGILSGLRMAELVSNKGKLSELLLEIPSYPNIREKIICSKEAKTAVMENMEDLLKDSFDDI
KEINSIDGVRLTFNDDSWVLVRPSGTEDYIRITLESKDSTKAQAIKETCVKIIKENI

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI31377548, Length=291, Percent_Identity=29.8969072164948, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1788361, Length=470, Percent_Identity=29.5744680851064, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789566, Length=458, Percent_Identity=30.1310043668122, Blast_Score=166, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71993870, Length=280, Percent_Identity=24.2857142857143, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71993878, Length=285, Percent_Identity=23.859649122807, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323934, Length=296, Percent_Identity=30.0675675675676, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 49370; Mature: 49370

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISLELKRVDSMAVKKLFGTSGIRGKINSEVTCELALNVGKSLACYLGNEGTVVLGYDT
CEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCEEEEEECC
RTTNVMLDQAICAGLLESGVDVIKIGMVPTPLVGYATDKLGADAGVMLTASHNPSQYNGI
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHCCCCCCEEEEECCCCCCCCCE
KIWNANGMAYTSAQEAKIEEIYSNESYTSVSWDKVGSLRVNEEIKGRYIDDLVGMVNIKP
EEECCCCEEECCHHHHHHHHHHCCCCCCEECHHCCCCEEECHHHCCCCHHHHHHHEECCC
GLKVVIDCASGAGSEISPLVFRKAGCEVTTLNSQPDGFFPGRNPEPNAENLQNLMKTVVA
CCEEEEEECCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IGADLGIAHDGDADRMITIDENGDISPFDSLLALMSKEFDGDIVTTVDAGLCMDESVKGN
HCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCC
VLRTKVGDVNVAEVIIEKDAAFGGEPSGTWLHPDFCMCPDGILSGLRMAELVSNKGKLSE
EEEEECCCCCHHHEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCHHHH
LLLEIPSYPNIREKIICSKEAKTAVMENMEDLLKDSFDDIKEINSIDGVRLTFNDDSWVL
HHHHCCCCCCHHHHHEECCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCEEE
VRPSGTEDYIRITLESKDSTKAQAIKETCVKIIKENI
EECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLISLELKRVDSMAVKKLFGTSGIRGKINSEVTCELALNVGKSLACYLGNEGTVVLGYDT
CEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCEEEEEECC
RTTNVMLDQAICAGLLESGVDVIKIGMVPTPLVGYATDKLGADAGVMLTASHNPSQYNGI
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHCCCCCCEEEEECCCCCCCCCE
KIWNANGMAYTSAQEAKIEEIYSNESYTSVSWDKVGSLRVNEEIKGRYIDDLVGMVNIKP
EEECCCCEEECCHHHHHHHHHHCCCCCCEECHHCCCCEEECHHHCCCCHHHHHHHEECCC
GLKVVIDCASGAGSEISPLVFRKAGCEVTTLNSQPDGFFPGRNPEPNAENLQNLMKTVVA
CCEEEEEECCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IGADLGIAHDGDADRMITIDENGDISPFDSLLALMSKEFDGDIVTTVDAGLCMDESVKGN
HCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCC
VLRTKVGDVNVAEVIIEKDAAFGGEPSGTWLHPDFCMCPDGILSGLRMAELVSNKGKLSE
EEEEECCCCCHHHEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCHHHH
LLLEIPSYPNIREKIICSKEAKTAVMENMEDLLKDSFDDIKEINSIDGVRLTFNDDSWVL
HHHHCCCCCCHHHHHEECCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCEEE
VRPSGTEDYIRITLESKDSTKAQAIKETCVKIIKENI
EECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA