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The map label for this gene is hpsA [H]

Identifier: 148642486

GI number: 148642486

Start: 407664

End: 408401

Strand: Reverse

Name: hpsA [H]

Synonym: Msm_0426

Alternate gene names: 148642486

Gene position: 408401-407664 (Counterclockwise)

Preceding gene: 148642492

Following gene: 148642485

Centisome position: 22.04

GC content: 33.47

Gene sequence:

>738_bases
ATGTCAGTAACACCTAGTGATTTATTACACAATAAAAAAGACTTAAATAAGAAAATTGATGTGGAAGATATAGATTTAAG
TGAAATATCCATTGAAGATTTGGTTTTCAATAAAAAAAACTATAAAAATTATATTAACTTGAAGTCTTTACTTGAAGGTG
TTTCCACCTGCCAAATTTCCGATGCATATAACGGAATTTCAAGAAGATCAGGTGTTATCAAAGAATTGAAACCTATTAAC
AGATTAAGGGTTTGGGGTAGAATTACTACCTGCAAAACCAACAGTGATGATTGGGGAACTTCCGCATTAGCTATTGATGA
AGCTAATGATGGAGATATATTATTTATTAAAACCAATAATTCTGACATGTCTGTATGGGGTGAATTAGCTTCAACCTGTG
CTAAAGCTAATGGTGTTAAAGCTACTGTAATTTATGGGTCTGTCAGAGATTTGGATGCTCTGTATTATATGGATTATCCT
ATTTTTGCTTGTGATTATGCTCCAAATGCAGGAAGTGCTTTAGGATTGGGAGAAATCAATGTGGATATTTCTGTTGGGGA
TATGACTATTCAACCAGGTGACTTTTTCTATGGTGATGAAACCGGCGTTGTTATTATTCCTCAGTCTTTGTTTAAACAGG
TCATGACTCAAACATTAGCTATTAAAGTAAAGGAATTAGGTATCATTGATGCTATTAATGGTGGTAAAACTTTGTCTCAG
GCTGCTGGGTTAAAATAG

Upstream 100 bases:

>100_bases
TACTAATATATATAATTAGTTAGTTATGTCAAAATTTTTGAAAAATCTTTTTTAAGCGGTTCTTACATATATCTATATAT
TAATTAAGAGAAGTGATTTA

Downstream 100 bases:

>100_bases
TGTTTAGGACAATTAAATAGTAAAACATTTAAATAGCAAATTTTATTGATATATAAATATATCGATACATTTATATATTA
TCACATGCATATTAATAGTT

Product: demethylmenaquinone methyltransferase

Products: NA

Alternate protein names: HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSVTPSDLLHNKKDLNKKIDVEDIDLSEISIEDLVFNKKNYKNYINLKSLLEGVSTCQISDAYNGISRRSGVIKELKPIN
RLRVWGRITTCKTNSDDWGTSALAIDEANDGDILFIKTNNSDMSVWGELASTCAKANGVKATVIYGSVRDLDALYYMDYP
IFACDYAPNAGSALGLGEINVDISVGDMTIQPGDFFYGDETGVVIIPQSLFKQVMTQTLAIKVKELGIIDAINGGKTLSQ
AAGLK

Sequences:

>Translated_245_residues
MSVTPSDLLHNKKDLNKKIDVEDIDLSEISIEDLVFNKKNYKNYINLKSLLEGVSTCQISDAYNGISRRSGVIKELKPIN
RLRVWGRITTCKTNSDDWGTSALAIDEANDGDILFIKTNNSDMSVWGELASTCAKANGVKATVIYGSVRDLDALYYMDYP
IFACDYAPNAGSALGLGEINVDISVGDMTIQPGDFFYGDETGVVIIPQSLFKQVMTQTLAIKVKELGIIDAINGGKTLSQ
AAGLK
>Mature_244_residues
SVTPSDLLHNKKDLNKKIDVEDIDLSEISIEDLVFNKKNYKNYINLKSLLEGVSTCQISDAYNGISRRSGVIKELKPINR
LRVWGRITTCKTNSDDWGTSALAIDEANDGDILFIKTNNSDMSVWGELASTCAKANGVKATVIYGSVRDLDALYYMDYPI
FACDYAPNAGSALGLGEINVDISVGDMTIQPGDFFYGDETGVVIIPQSLFKQVMTQTLAIKVKELGIIDAINGGKTLSQA
AGLK

Specific function: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate [H]

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017120
- InterPro:   IPR001754
- InterPro:   IPR011060
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6; PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 26718; Mature: 26586

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTPSDLLHNKKDLNKKIDVEDIDLSEISIEDLVFNKKNYKNYINLKSLLEGVSTCQIS
CCCCHHHHHCCHHHCCCCCCCCCCCCCCEEHHHHEECCCCCHHHCCHHHHHCHHHEEEEC
DAYNGISRRSGVIKELKPINRLRVWGRITTCKTNSDDWGTSALAIDEANDGDILFIKTNN
HHHCCHHHHCCHHHHHHHHHHEEEEEEEEEEECCCCCCCCEEEEEECCCCCCEEEEEECC
SDMSVWGELASTCAKANGVKATVIYGSVRDLDALYYMDYPIFACDYAPNAGSALGLGEIN
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCEEECCEEE
VDISVGDMTIQPGDFFYGDETGVVIIPQSLFKQVMTQTLAIKVKELGIIDAINGGKTLSQ
EEEEECCEEECCCCEEECCCCCEEEECHHHHHHHHHHHHHEEEECCCEEEECCCCCHHHH
AAGLK
HCCCC
>Mature Secondary Structure 
SVTPSDLLHNKKDLNKKIDVEDIDLSEISIEDLVFNKKNYKNYINLKSLLEGVSTCQIS
CCCHHHHHCCHHHCCCCCCCCCCCCCCEEHHHHEECCCCCHHHCCHHHHHCHHHEEEEC
DAYNGISRRSGVIKELKPINRLRVWGRITTCKTNSDDWGTSALAIDEANDGDILFIKTNN
HHHCCHHHHCCHHHHHHHHHHEEEEEEEEEEECCCCCCCCEEEEEECCCCCCEEEEEECC
SDMSVWGELASTCAKANGVKATVIYGSVRDLDALYYMDYPIFACDYAPNAGSALGLGEIN
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCEEECCEEE
VDISVGDMTIQPGDFFYGDETGVVIIPQSLFKQVMTQTLAIKVKELGIIDAINGGKTLSQ
EEEEECCEEECCCCEEECCCCCEEEECHHHHHHHHHHHHHEEEECCCEEEECCCCCHHHH
AAGLK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA