Click here to switch to the map view.

The map label for this gene is murC [H]

Identifier: 148642419

GI number: 148642419

Start: 341986

End: 343422

Strand: Reverse

Name: murC [H]

Synonym: Msm_0359

Alternate gene names: 148642419

Gene position: 343422-341986 (Counterclockwise)

Preceding gene: 148642420

Following gene: 148642418

Centisome position: 18.53

GC content: 31.11

Gene sequence:

>1437_bases
ATGATTATACAGGATTTAGCTAGTTTTATTGAAGGTAATATTGTTGGAAAAGATAGTTTTTTTGATGATGAGGGATTTAC
AGGGAAATTTACATTTTTAAATGATGCTGTAGAAGGTGACATTGTAATAAGACATAAAATTAATGGTAAAGGGGTAGAAA
TTGCAGCAGGTAAAAATTTAGCCTGTTTAATTACTCAAACTCCTCAGGATGGGGCATGTGATAAGGCAAAAGAATTGAAT
TTTCCGTTGATTGTTGTAGATAAGATAGAATTGGCTACTGCTTATGCTCTTAAATGGACTGTTGAAAAGTTTTCTCCAGA
TTCAAAAAATGTTATTATAACTGGAACCAATGGAAAATCAACAACATCTCATTTAATTTATCATATTTTAAAAAACACTG
GAGTACATGTTCTTACAAATACTGACAGCGAATCAGAATTCAACACATTAATTGACCCTATGGTTTCTAAACTAATTTCT
GATGAAGTTAAAAATAATGGAAAACTGGACTATCTGGTTATTGAGGTTTCAGAAGTTCAGGGCTGGCTTGGAAACTTAAT
GAAACATCATGCATATCTGATGGCCAGTGCAGTTAAACCAAGTGTTGGAGTTATAACTAATATAGCTATGGATCATATAG
GTCTTGTAAATTCCATTGATGAAGTTTTTGATGAAATAAATCAGGTTCCCAATGCTATTGGAGATGGGGTAACAGTATTG
AATTATGATGATGATTTGGTGATGAAATTAACCCCAAAACATCCTTTTTTATGTTCTATGAATAATATGGACTCAAAAAA
TCCTAATGTTTATTATGATAATGGAATTTTTTATGAAGGTAAACGGATTTTGGAAAACAAAGATTTGCCTTTTACTTCCC
ATCACTTTATTCAAAATATTTTATCAGCAGTTGCAGCATGCATATCTTTAAATATGGATATAGAAGATATTGTTGAAGGT
GTAAAATCTTACCGCCCATTAAACAGAAGGTTTTCAAAACTTCATGAAAATCCATTGATTGTAGATGATTTTGCACATAA
TCCTGACGGTATAAAAGCTACAATTGCTGAGACCCGTAAATTACTTGCTGAAAACCAAACATTATATGTTGTATGTTCAA
TCAGGGGTTCAAGAGGTGTAGAAATCAACAAATTGAATGTTGAAGCATTGGCTGAATCTATGGATGATAATATAAAATTA
GTTCTGTCTTCAAGTAATGATGTTGTTGACCATTTGAATTTTGTTGAAGATGAAGAGCGTGAAATTTTCTTTGAAGTTTT
AAATCAGAACAATATTGATTATAATTATTTTGATAATTTATGTGACTGTTTAAAAGACACATACAAGTGTGCTGATGCAA
ATGATATTATTTTATTAATTGGTGCACAGGGAATGGACCCTGCTGAAGGTCTTTTGGAAAATATTTTAAGGAAATAA

Upstream 100 bases:

>100_bases
ACTTAGCTATTGGGGTGTTACTGTATGGTTATGTGTAATTGGAATTCTCGCTCAATTATACATATTCTAATTTTTCTTTT
TCTTTTTTTGGTGATTTTAT

Downstream 100 bases:

>100_bases
TTTAAATATTACAAAATTTTAATATAATAAATGTAATTTATTTTTCTATTGCTTATTGATGGAAAAATTTAGAGGATAAA
AACATGTTTATAAAGATAAG

Product: peptide ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MIIQDLASFIEGNIVGKDSFFDDEGFTGKFTFLNDAVEGDIVIRHKINGKGVEIAAGKNLACLITQTPQDGACDKAKELN
FPLIVVDKIELATAYALKWTVEKFSPDSKNVIITGTNGKSTTSHLIYHILKNTGVHVLTNTDSESEFNTLIDPMVSKLIS
DEVKNNGKLDYLVIEVSEVQGWLGNLMKHHAYLMASAVKPSVGVITNIAMDHIGLVNSIDEVFDEINQVPNAIGDGVTVL
NYDDDLVMKLTPKHPFLCSMNNMDSKNPNVYYDNGIFYEGKRILENKDLPFTSHHFIQNILSAVAACISLNMDIEDIVEG
VKSYRPLNRRFSKLHENPLIVDDFAHNPDGIKATIAETRKLLAENQTLYVVCSIRGSRGVEINKLNVEALAESMDDNIKL
VLSSSNDVVDHLNFVEDEEREIFFEVLNQNNIDYNYFDNLCDCLKDTYKCADANDIILLIGAQGMDPAEGLLENILRK

Sequences:

>Translated_478_residues
MIIQDLASFIEGNIVGKDSFFDDEGFTGKFTFLNDAVEGDIVIRHKINGKGVEIAAGKNLACLITQTPQDGACDKAKELN
FPLIVVDKIELATAYALKWTVEKFSPDSKNVIITGTNGKSTTSHLIYHILKNTGVHVLTNTDSESEFNTLIDPMVSKLIS
DEVKNNGKLDYLVIEVSEVQGWLGNLMKHHAYLMASAVKPSVGVITNIAMDHIGLVNSIDEVFDEINQVPNAIGDGVTVL
NYDDDLVMKLTPKHPFLCSMNNMDSKNPNVYYDNGIFYEGKRILENKDLPFTSHHFIQNILSAVAACISLNMDIEDIVEG
VKSYRPLNRRFSKLHENPLIVDDFAHNPDGIKATIAETRKLLAENQTLYVVCSIRGSRGVEINKLNVEALAESMDDNIKL
VLSSSNDVVDHLNFVEDEEREIFFEVLNQNNIDYNYFDNLCDCLKDTYKCADANDIILLIGAQGMDPAEGLLENILRK
>Mature_478_residues
MIIQDLASFIEGNIVGKDSFFDDEGFTGKFTFLNDAVEGDIVIRHKINGKGVEIAAGKNLACLITQTPQDGACDKAKELN
FPLIVVDKIELATAYALKWTVEKFSPDSKNVIITGTNGKSTTSHLIYHILKNTGVHVLTNTDSESEFNTLIDPMVSKLIS
DEVKNNGKLDYLVIEVSEVQGWLGNLMKHHAYLMASAVKPSVGVITNIAMDHIGLVNSIDEVFDEINQVPNAIGDGVTVL
NYDDDLVMKLTPKHPFLCSMNNMDSKNPNVYYDNGIFYEGKRILENKDLPFTSHHFIQNILSAVAACISLNMDIEDIVEG
VKSYRPLNRRFSKLHENPLIVDDFAHNPDGIKATIAETRKLLAENQTLYVVCSIRGSRGVEINKLNVEALAESMDDNIKL
VLSSSNDVVDHLNFVEDEEREIFFEVLNQNNIDYNYFDNLCDCLKDTYKCADANDIILLIGAQGMDPAEGLLENILRK

Specific function: Cell wall formation [H]

COG id: COG0769

COG function: function code M; UDP-N-acetylmuramyl tripeptide synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 53198; Mature: 53198

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS01011 FOLYLPOLYGLU_SYNT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIQDLASFIEGNIVGKDSFFDDEGFTGKFTFLNDAVEGDIVIRHKINGKGVEIAAGKNL
CCHHHHHHHHCCCEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEECCCCE
ACLITQTPQDGACDKAKELNFPLIVVDKIELATAYALKWTVEKFSPDSKNVIITGTNGKS
EEEEEECCCCCCCCCHHHCCCCEEEEECCHHHEEEEEEEEHHHCCCCCCEEEEECCCCCC
TTSHLIYHILKNTGVHVLTNTDSESEFNTLIDPMVSKLISDEVKNNGKLDYLVIEVSEVQ
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
GWLGNLMKHHAYLMASAVKPSVGVITNIAMDHIGLVNSIDEVFDEINQVPNAIGDGVTVL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NYDDDLVMKLTPKHPFLCSMNNMDSKNPNVYYDNGIFYEGKRILENKDLPFTSHHFIQNI
ECCCCEEEEECCCCCEEEECCCCCCCCCCEEECCCEEECCCHHCCCCCCCCHHHHHHHHH
LSAVAACISLNMDIEDIVEGVKSYRPLNRRFSKLHENPLIVDDFAHNPDGIKATIAETRK
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCCCEEHHHHHHH
LLAENQTLYVVCSIRGSRGVEINKLNVEALAESMDDNIKLVLSSSNDVVDHLNFVEDEER
HHHCCCEEEEEEEECCCCCCEEEEECHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCHHH
EIFFEVLNQNNIDYNYFDNLCDCLKDTYKCADANDIILLIGAQGMDPAEGLLENILRK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIIQDLASFIEGNIVGKDSFFDDEGFTGKFTFLNDAVEGDIVIRHKINGKGVEIAAGKNL
CCHHHHHHHHCCCEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEECCCCE
ACLITQTPQDGACDKAKELNFPLIVVDKIELATAYALKWTVEKFSPDSKNVIITGTNGKS
EEEEEECCCCCCCCCHHHCCCCEEEEECCHHHEEEEEEEEHHHCCCCCCEEEEECCCCCC
TTSHLIYHILKNTGVHVLTNTDSESEFNTLIDPMVSKLISDEVKNNGKLDYLVIEVSEVQ
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
GWLGNLMKHHAYLMASAVKPSVGVITNIAMDHIGLVNSIDEVFDEINQVPNAIGDGVTVL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NYDDDLVMKLTPKHPFLCSMNNMDSKNPNVYYDNGIFYEGKRILENKDLPFTSHHFIQNI
ECCCCEEEEECCCCCEEEECCCCCCCCCCEEECCCEEECCCHHCCCCCCCCHHHHHHHHH
LSAVAACISLNMDIEDIVEGVKSYRPLNRRFSKLHENPLIVDDFAHNPDGIKATIAETRK
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCCCEEHHHHHHH
LLAENQTLYVVCSIRGSRGVEINKLNVEALAESMDDNIKLVLSSSNDVVDHLNFVEDEER
HHHCCCEEEEEEEECCCCCCEEEEECHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCHHH
EIFFEVLNQNNIDYNYFDNLCDCLKDTYKCADANDIILLIGAQGMDPAEGLLENILRK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA