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The map label for this gene is ctpC [H]

Identifier: 148642353

GI number: 148642353

Start: 283970

End: 286093

Strand: Reverse

Name: ctpC [H]

Synonym: Msm_0293

Alternate gene names: 148642353

Gene position: 286093-283970 (Counterclockwise)

Preceding gene: 148642354

Following gene: 148642351

Centisome position: 15.44

GC content: 33.19

Gene sequence:

>2124_bases
ATGAAATACCAAGTAATGTATAATAACGGAACTCGTATCAGAGTTCGTTCAGGCCAGGCTGCCTTCACCAAAAAGGAGGG
TTATGGTATTTCTTCATTGCTTTTAGAAAATAATTTTATTAAAAAAGTTTTCACATCTCATAGAAACGGAAGTATTTTAA
TCTATTATGATGATGTTAAAAACAGAGACAAAGTCTTTGCAGCACTTGATAAAATAACTGAGGATGATTTGGTTGAAGTT
GAACCTGACATGTACATGAGTTCAAATGAGTTAACTAATAATTTTTGGGTTAGTTTATCAGGTATGCTTGTGAGAAGGGT
ATTAGGTAAAATTGTATTGCCTATTCCAATTAGGAATTTATTGACTGTTTATAGAGCTATTAAGTATATATGGCATGCTT
TAGACAGTTTAACAAGTTTCAGAGTGGATGTTGCTCTACTTGATGGTGCAGCAGTTACCGGATCACTTCTTAAAAGAGAT
TTCGATCCGGCAAGTTCTATGATGTTTTTATTATCAATTTCCGATTTGCTTGAAGACTACACATTACAAAAAACAAAAAA
TACTTTAAAAGAAAGTTTAACTTTAAATATTGATACTGTATGGGTAGTAAATGAAGATGGTGAGGAAATACAACAACCTA
TATCCCAAATTAACAAAGATGATAAAATTAAAGTTCATATGGGTGATGTAATACCTGTAGATGGTAAAGTTGTTGACGGT
GAAGGGATGGTTAATGAAGCAACCATGACTGGAGAACCATTGGCTGTCCATAAAATGCCTGGAAAAACAGTTCATGCAGG
TACTGTTGTTGAAGAAGGTAATCTGATTGTTCAAGTTTATTCTTTTGATAAAGAAACCAGATTAAATAAAATTATAAATC
TTATTGAGAATTCAGAAGAATTAAAAGCAGATGCTCAAAGTAAAGCTGAGGAATTGGCAGACTCTATTGTGCCATACAGT
TTCCTTACAACATTCCTTACTTATCTGATAACAAGGGATACTACAAAAGCATTGTCTGTTTTAATGGTTGATTTCTCATG
TGCACTTAAATTAACAACTCCATTATCTGTTATTTCAGCAATGAAAGAAGCTTCAGATAATAGGATGATGGTTAAAGGTG
GAAAATTCCTTGAAAAATATGCAACTGCAGATACAATAGTGTTCGACAAAACAGGAACTCTTACTAATGCAACTCCAAAA
GTTGTTGATGTAATTTCTCTTGGAGATTACTCCAGAGATGAAATTTTAAGAATGTCTGCATGTATTGAAGAGCATTTTGC
ACATAGTATTGCTACGGCTATTGTAAAACAGGCTGAAGAGGAAGGTCTAAAACATGATGAAGACCATAGTGAAGTTGAAT
ATATTGTAGCTCATGGTATTGCAACAAGTTATAATGGCAAACGTGCTGTTATAGGAAGCAGACACTTTTTATTTGATGAT
GAAGGTGTAGAAATATCCAAAGAAGATGAAAAACTCATTGACGAAAAAGTCTGTGAATATTCGGTTGTTTATTTGGCTAT
TGATAATAAACTTGAAGGTATCATATGTATTAACGACCCTGTAAGAAAAGAAGCTAGGGATGTTATTGAAGAGCTTAAAA
AATTAGGTATTGAAAATGTTATCATGTTGACTGGAGACAGTGAAAGTGGTGCAAAAAGCAGCGCTGAAGCATTGGGCATA
ACTGAATACCGCTCACAGGTGCTTCCTGAAGATAAGGCCAGTATTGTTGAAAGTTTAAAAGAAGAAGGCAGAACTATTAT
TATGGTCGGAGATGGAATAAATGATTCTCCTGCATTGGCTGCTGCTGATGTGTCTGTTTCAATGAAAAACTCTTCAGATA
TTGCCAGAGAAGTTGCAGATGTTTCTTTATTGTCTGATAATTTATATGATTTAATAACACTTAGAAAATTGAGTGTTGGT
ATGTTAAATAAAATAGATACTAATTATCACAGTATAATTGGCATTAACGGTTCTTTAATAGCACTGGGTATGTTTGGAAT
TATAACTCCATCAACATCTTCATTGATACATAATTTATCAACTATGCTTTTAGGAGCTTTAAGTACACGTTCTGTATTAA
AAGAACCAAGGGAAATAGAAGTTAATGTAGTAGAAACTGCATAA

Upstream 100 bases:

>100_bases
TACCAGGACATGGTTCAAAATGCGGAGGACATTGTTGTTGATGCTAATAAAGATGATAAAAAAGCAATTTATGTTGAAGA
TGACGAATAAGGTTTAAAAC

Downstream 100 bases:

>100_bases
ACTTCTTATTTTATTTTTTAAGCTATTGATGTAAATATTGTATATGACATCAGTAATATAAAACAGATTATCCCCGGATT
TAAAAGGATTGTACTTACTG

Product: cation transporter HAD ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 707

Protein sequence:

>707_residues
MKYQVMYNNGTRIRVRSGQAAFTKKEGYGISSLLLENNFIKKVFTSHRNGSILIYYDDVKNRDKVFAALDKITEDDLVEV
EPDMYMSSNELTNNFWVSLSGMLVRRVLGKIVLPIPIRNLLTVYRAIKYIWHALDSLTSFRVDVALLDGAAVTGSLLKRD
FDPASSMMFLLSISDLLEDYTLQKTKNTLKESLTLNIDTVWVVNEDGEEIQQPISQINKDDKIKVHMGDVIPVDGKVVDG
EGMVNEATMTGEPLAVHKMPGKTVHAGTVVEEGNLIVQVYSFDKETRLNKIINLIENSEELKADAQSKAEELADSIVPYS
FLTTFLTYLITRDTTKALSVLMVDFSCALKLTTPLSVISAMKEASDNRMMVKGGKFLEKYATADTIVFDKTGTLTNATPK
VVDVISLGDYSRDEILRMSACIEEHFAHSIATAIVKQAEEEGLKHDEDHSEVEYIVAHGIATSYNGKRAVIGSRHFLFDD
EGVEISKEDEKLIDEKVCEYSVVYLAIDNKLEGIICINDPVRKEARDVIEELKKLGIENVIMLTGDSESGAKSSAEALGI
TEYRSQVLPEDKASIVESLKEEGRTIIMVGDGINDSPALAAADVSVSMKNSSDIAREVADVSLLSDNLYDLITLRKLSVG
MLNKIDTNYHSIIGINGSLIALGMFGIITPSTSSLIHNLSTMLLGALSTRSVLKEPREIEVNVVETA

Sequences:

>Translated_707_residues
MKYQVMYNNGTRIRVRSGQAAFTKKEGYGISSLLLENNFIKKVFTSHRNGSILIYYDDVKNRDKVFAALDKITEDDLVEV
EPDMYMSSNELTNNFWVSLSGMLVRRVLGKIVLPIPIRNLLTVYRAIKYIWHALDSLTSFRVDVALLDGAAVTGSLLKRD
FDPASSMMFLLSISDLLEDYTLQKTKNTLKESLTLNIDTVWVVNEDGEEIQQPISQINKDDKIKVHMGDVIPVDGKVVDG
EGMVNEATMTGEPLAVHKMPGKTVHAGTVVEEGNLIVQVYSFDKETRLNKIINLIENSEELKADAQSKAEELADSIVPYS
FLTTFLTYLITRDTTKALSVLMVDFSCALKLTTPLSVISAMKEASDNRMMVKGGKFLEKYATADTIVFDKTGTLTNATPK
VVDVISLGDYSRDEILRMSACIEEHFAHSIATAIVKQAEEEGLKHDEDHSEVEYIVAHGIATSYNGKRAVIGSRHFLFDD
EGVEISKEDEKLIDEKVCEYSVVYLAIDNKLEGIICINDPVRKEARDVIEELKKLGIENVIMLTGDSESGAKSSAEALGI
TEYRSQVLPEDKASIVESLKEEGRTIIMVGDGINDSPALAAADVSVSMKNSSDIAREVADVSLLSDNLYDLITLRKLSVG
MLNKIDTNYHSIIGINGSLIALGMFGIITPSTSSLIHNLSTMLLGALSTRSVLKEPREIEVNVVETA
>Mature_707_residues
MKYQVMYNNGTRIRVRSGQAAFTKKEGYGISSLLLENNFIKKVFTSHRNGSILIYYDDVKNRDKVFAALDKITEDDLVEV
EPDMYMSSNELTNNFWVSLSGMLVRRVLGKIVLPIPIRNLLTVYRAIKYIWHALDSLTSFRVDVALLDGAAVTGSLLKRD
FDPASSMMFLLSISDLLEDYTLQKTKNTLKESLTLNIDTVWVVNEDGEEIQQPISQINKDDKIKVHMGDVIPVDGKVVDG
EGMVNEATMTGEPLAVHKMPGKTVHAGTVVEEGNLIVQVYSFDKETRLNKIINLIENSEELKADAQSKAEELADSIVPYS
FLTTFLTYLITRDTTKALSVLMVDFSCALKLTTPLSVISAMKEASDNRMMVKGGKFLEKYATADTIVFDKTGTLTNATPK
VVDVISLGDYSRDEILRMSACIEEHFAHSIATAIVKQAEEEGLKHDEDHSEVEYIVAHGIATSYNGKRAVIGSRHFLFDD
EGVEISKEDEKLIDEKVCEYSVVYLAIDNKLEGIICINDPVRKEARDVIEELKKLGIENVIMLTGDSESGAKSSAEALGI
TEYRSQVLPEDKASIVESLKEEGRTIIMVGDGINDSPALAAADVSVSMKNSSDIAREVADVSLLSDNLYDLITLRKLSVG
MLNKIDTNYHSIIGINGSLIALGMFGIITPSTSSLIHNLSTMLLGALSTRSVLKEPREIEVNVVETA

Specific function: Involved In Copper Efflux. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=585, Percent_Identity=29.5726495726496, Blast_Score=232, Evalue=7e-61,
Organism=Homo sapiens, GI115529486, Length=601, Percent_Identity=28.6189683860233, Blast_Score=232, Evalue=8e-61,
Organism=Homo sapiens, GI55743073, Length=532, Percent_Identity=30.8270676691729, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI48762691, Length=161, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48762689, Length=161, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48762687, Length=161, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI48762685, Length=161, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786691, Length=547, Percent_Identity=30.5301645338208, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1789879, Length=535, Percent_Identity=28.2242990654206, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1786914, Length=462, Percent_Identity=24.8917748917749, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI2367363, Length=200, Percent_Identity=33, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17556548, Length=593, Percent_Identity=28.6677908937605, Blast_Score=172, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6320475, Length=567, Percent_Identity=28.3950617283951, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6319772, Length=520, Percent_Identity=23.8461538461538, Blast_Score=143, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6321430, Length=563, Percent_Identity=22.5577264653641, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6325221, Length=555, Percent_Identity=21.8018018018018, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321271, Length=168, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321432, Length=155, Percent_Identity=32.258064516129, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI221329854, Length=362, Percent_Identity=28.7292817679558, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24668704, Length=148, Percent_Identity=32.4324324324324, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24668708, Length=148, Percent_Identity=32.4324324324324, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281366617, Length=148, Percent_Identity=32.4324324324324, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24668696, Length=148, Percent_Identity=32.4324324324324, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161085803, Length=148, Percent_Identity=32.4324324324324, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 78100; Mature: 78100

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00154 ATPASE_E1_E2 ; PS00178 AA_TRNA_LIGASE_I ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQVMYNNGTRIRVRSGQAAFTKKEGYGISSLLLENNFIKKVFTSHRNGSILIYYDDVK
CEEEEEECCCCEEEEECCCEEEEECCCCCHHHHHHCCHHHHHHHHCCCCCEEEEEECCCC
NRDKVFAALDKITEDDLVEVEPDMYMSSNELTNNFWVSLSGMLVRRVLGKIVLPIPIRNL
CHHHHHHHHHHCCCCCCEEECCCCEECCCCCCCEEEEEHHHHHHHHHHHHEECCCCHHHH
LTVYRAIKYIWHALDSLTSFRVDVALLDGAAVTGSLLKRDFDPASSMMFLLSISDLLEDY
HHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TLQKTKNTLKESLTLNIDTVWVVNEDGEEIQQPISQINKDDKIKVHMGDVIPVDGKVVDG
HHHHHHHHHHHCEEEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCEEECCCEEECC
EGMVNEATMTGEPLAVHKMPGKTVHAGTVVEEGNLIVQVYSFDKETRLNKIINLIENSEE
CCCEECCCCCCCCEEEECCCCCEEECCEEEECCCEEEEEECCCCHHHHHHHHHHHCCCHH
LKADAQSKAEELADSIVPYSFLTTFLTYLITRDTTKALSVLMVDFSCALKLTTPLSVISA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHEEHEEEEEECCHHHHHHH
MKEASDNRMMVKGGKFLEKYATADTIVFDKTGTLTNATPKVVDVISLGDYSRDEILRMSA
HHHCCCCEEEEECCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
CIEEHFAHSIATAIVKQAEEEGLKHDEDHSEVEYIVAHGIATSYNGKRAVIGSRHFLFDD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEECCCCCEEEEECCEEEECC
EGVEISKEDEKLIDEKVCEYSVVYLAIDNKLEGIICINDPVRKEARDVIEELKKLGIENV
CCCEECCHHHHHHHHHHHCEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEE
IMLTGDSESGAKSSAEALGITEYRSQVLPEDKASIVESLKEEGRTIIMVGDGINDSPALA
EEEECCCCCCCCCCHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEE
AADVSVSMKNSSDIAREVADVSLLSDNLYDLITLRKLSVGMLNKIDTNYHSIIGINGSLI
EEEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEE
ALGMFGIITPSTSSLIHNLSTMLLGALSTRSVLKEPREIEVNVVETA
EEEHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
>Mature Secondary Structure
MKYQVMYNNGTRIRVRSGQAAFTKKEGYGISSLLLENNFIKKVFTSHRNGSILIYYDDVK
CEEEEEECCCCEEEEECCCEEEEECCCCCHHHHHHCCHHHHHHHHCCCCCEEEEEECCCC
NRDKVFAALDKITEDDLVEVEPDMYMSSNELTNNFWVSLSGMLVRRVLGKIVLPIPIRNL
CHHHHHHHHHHCCCCCCEEECCCCEECCCCCCCEEEEEHHHHHHHHHHHHEECCCCHHHH
LTVYRAIKYIWHALDSLTSFRVDVALLDGAAVTGSLLKRDFDPASSMMFLLSISDLLEDY
HHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TLQKTKNTLKESLTLNIDTVWVVNEDGEEIQQPISQINKDDKIKVHMGDVIPVDGKVVDG
HHHHHHHHHHHCEEEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCEEECCCEEECC
EGMVNEATMTGEPLAVHKMPGKTVHAGTVVEEGNLIVQVYSFDKETRLNKIINLIENSEE
CCCEECCCCCCCCEEEECCCCCEEECCEEEECCCEEEEEECCCCHHHHHHHHHHHCCCHH
LKADAQSKAEELADSIVPYSFLTTFLTYLITRDTTKALSVLMVDFSCALKLTTPLSVISA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHEEHEEEEEECCHHHHHHH
MKEASDNRMMVKGGKFLEKYATADTIVFDKTGTLTNATPKVVDVISLGDYSRDEILRMSA
HHHCCCCEEEEECCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
CIEEHFAHSIATAIVKQAEEEGLKHDEDHSEVEYIVAHGIATSYNGKRAVIGSRHFLFDD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEECCCCCEEEEECCEEEECC
EGVEISKEDEKLIDEKVCEYSVVYLAIDNKLEGIICINDPVRKEARDVIEELKKLGIENV
CCCEECCHHHHHHHHHHHCEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEE
IMLTGDSESGAKSSAEALGITEYRSQVLPEDKASIVESLKEEGRTIIMVGDGINDSPALA
EEEECCCCCCCCCCHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEE
AADVSVSMKNSSDIAREVADVSLLSDNLYDLITLRKLSVGMLNKIDTNYHSIIGINGSLI
EEEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEE
ALGMFGIITPSTSSLIHNLSTMLLGALSTRSVLKEPREIEVNVVETA
EEEHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]