| Definition | Methanobrevibacter smithii ATCC 35061 chromosome, complete genome. |
|---|---|
| Accession | NC_009515 |
| Length | 1,853,160 |
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The map label for this gene is rad50 [H]
Identifier: 148642180
GI number: 148642180
Start: 115743
End: 118496
Strand: Reverse
Name: rad50 [H]
Synonym: Msm_0120
Alternate gene names: 148642180
Gene position: 118496-115743 (Counterclockwise)
Preceding gene: 148642181
Following gene: 148642178
Centisome position: 6.39
GC content: 29.67
Gene sequence:
>2754_bases ATGATTTTTACAAAATTAACATTAAACAATTTCAAATCCTATGGTCATGAAGTTATTAAGTTTGGTGATGGGATTACAGT TATTGTAGGGGAAAATGGTGCTGGAAAATCTACTATTTTAGAAGCTATTAGTTTCGCATTATTTAAACAGCATACTGCTA AAAAAATTGATGATCTGGTAAGAAATGGCAGTGATGAAAATATGTATGTTGATTTGGAATTTGTTTCCAATGGTAAAGAA TATAAAATTCATCGTGAAAAAACCAAATCAGGTTTGAAATCAACACTTCTTAAAAAAACTACTTCTAAAGGCCAATTTAT CCCATCATGTGCTGGAGATAAAGAGGTAGCTAATGAAATCCAATCTATTTTGGATATTGATTCTGATTTGTTTTTAAATG CAATATACATAAGACAGGGGGAAATTGCAGAACTAGTTGATAAAACCTCATCTGAGAAAAAGCAGTTAATCGGAAAATTA TTAGGTTTGGATTCCCTTGAAAAAGCATGGAAAAACTTGCAGCCAATTATCAGCAACTATGAAAAAACCCAGTCAGAACT TAAAGGTAAGTTATTTTCATCTGAAGAATTAAAAGAGGAATATGATCATAAAAAAGCATTGTTAGGCAGTCTTAAAGAAA AAGGACTTGATTTAGAAAAACAAATTGAAGAAGTCAAAGAGATGAAAGCTGAAAAGCAAAATGAAAAAACCAATATGGAA AGGGAAAAGGAAATCTTTGATAACTTCAATAACAATTTGGATGCTGAGAAAAAAAGATTGGAGTCTCTTGAAAATGATAA AAGAACACTTCAAGATAATTTGGATGAAATAAAAAAAGCTGAAGAGCAAATTGCAAGATTGGAAAAATTTGTTAAGAAAT TGCCCCTGTATCTTGACTTTGAAAAGTCTGTTACAAGCATTCAACAGTTAGAGCTTGATAAACAAAAAATTGAAAAAGAT TTGGATTCAATTGCAACACAGGAAGAACTTTTAGCAACTAAAAAAGAGGGATATAATAAATTTTTAGCAGCTGATGAGCA GATTGAAAAATTAAACAATCAAAAAATCAATCTGGAAAAAGAATTGGCTACTCTTACCCAGCTTGAAAAAGATAAAAAGC AACTTCTCAAATCAATTGAAGGAAATAGAAATGAAATTGAAAGGTTCTTTTCTGTAACTAAGGATAATCTGTATGATAAC GGTTTGTCTCAGGATATTCTGACAGATGTTGATAATTTCACTCAGTTGGAAGAGGTTACTGACAACTTTAGTGAAGAAGT TTCCAATAAAGTTAAGGATTTAAGTCTTGAGATTATTTCTAAAAATGAGGAAATTGTCAAATTTAAACAGGCTATTGAAA CAGCACAAAAACCTTTAGATGAATTGGGAGATGTTGAAAATAAATGTCCTGTCTGTCAGTCGGATATCAATCCTCAAAAG AAAAATGAATTGATTGATTCTTATAATAATGAAATTAAGATTAATGAAAAATCTATTGAGGAAAATAAGGAAAATATCCG TCTTTTAAATAAAAATAAAGATAGTTTTGAAGAAAAATACAACAGACTCCAGGAATTATCTAAAGATATCATAGGATATA AAAACAAATTTGATAATTTAGAAAAAGATCTGGTTAGGCTTAATGAAATTGATGACGGACTGGAATCTAAAGAGTACACC AATACTAAATTAGGCGAACTTATATTGGATATCTCTAAAGAGAAAGTTGGACGTGAAGAAAATAAAGAGGATTATGATGC ATACATAAAATCAAAAGGAGCTCTTGATGTTTTAAGCAGTAAAACTGAACTTCAATATAAGTTAAATCAGGTTAATAATG AAGTTGATGTCCATGTTAAAAACATTAAATTAGCTATTGATCAGGACCCTCATTTAAGTGGGGATATGAGTACTGCTGAT TTGCAGGCACGTATTACTGATTTAAAAAATAAAGAAGAAGAATTTAATCAGCTTAAAGGTTTTGTTCAAAATAAAAAGGC TCTTGAATCTCAATTAATCTCTAAAAAAGATGATATTGGTGTTTCATTAAATCAGATTGAAATCCTGAAAAATAAAATAG AAGCTTCTGTTTATGATAAAGAAAAATACGAAAAAGTAATCTACTTCTATGAAGTCTATGAAAGAAGATATGATGAATTT GCAGGTGAGCTTTCAGAAATTAAAGGTCAGGCTAAAGAATTAATAGCTAATGTTAATGTTTTGGCAGAAAAAATATTAAC TAACTATAAATTCCAGCAGGAATACAAAAACACTACTGATTATATTGATTTATTAAATCATATCAGAACATTGTATTCTA AAAATGGTATACAAAAAGAATTGAGGAACCGTTCAAGGCCGGTAATTCAGAAATACACTAAAGACTTCTTTGATGAATTT AACTTTAATTATTCTGATTTAACATTGGATGAGGACTATGAAGTAACTGTATTCGGTCCTGAAGGTGAAGCTTCAATGAG TATGGTAAGTGGTGGTGAAAAAATAGCTATTGCTCTTGCTTTAAGATTAGGTATTACTAAGGCTAAGGCAAAAGGTGATT TGGAAACTATTCTTTTAGACGAGCCTACAATACATTTAGACAGCTTTAGAAGACATGAGCTAATTAATTTGTTAAAAGAT ATGACTGTTTTACCGCAAATGATTATTGTAACTCATGAAAGCCAGCTTGAAAATGCTGCAGATAATTTGGTTAAAGTAGA AAAAAATAATGGTATTTCAAAAGTATCTAATTAG
Upstream 100 bases:
>100_bases TTTTCAATGAAAAATACAATATTATACGTGATGATTCCGGTGAGGAAATAACTGAAAACAAAGCTGAAGACGGTCAGGTA AGATTTAGTGGGGCTATTCA
Downstream 100 bases:
>100_bases ATACTTTTTATTTTTTTTTAAGTGATTAATGTTGGGATTTAGATTCTGCCCATTTCCTCAGCATTTTTTATTGCATCTAC AATACAGTTTGCATTCCATC
Product: purine NTPase involved in DNA repair, Rad50
Products: 5'-phosphomonoesters [C]
Alternate protein names: NA
Number of amino acids: Translated: 917; Mature: 917
Protein sequence:
>917_residues MIFTKLTLNNFKSYGHEVIKFGDGITVIVGENGAGKSTILEAISFALFKQHTAKKIDDLVRNGSDENMYVDLEFVSNGKE YKIHREKTKSGLKSTLLKKTTSKGQFIPSCAGDKEVANEIQSILDIDSDLFLNAIYIRQGEIAELVDKTSSEKKQLIGKL LGLDSLEKAWKNLQPIISNYEKTQSELKGKLFSSEELKEEYDHKKALLGSLKEKGLDLEKQIEEVKEMKAEKQNEKTNME REKEIFDNFNNNLDAEKKRLESLENDKRTLQDNLDEIKKAEEQIARLEKFVKKLPLYLDFEKSVTSIQQLELDKQKIEKD LDSIATQEELLATKKEGYNKFLAADEQIEKLNNQKINLEKELATLTQLEKDKKQLLKSIEGNRNEIERFFSVTKDNLYDN GLSQDILTDVDNFTQLEEVTDNFSEEVSNKVKDLSLEIISKNEEIVKFKQAIETAQKPLDELGDVENKCPVCQSDINPQK KNELIDSYNNEIKINEKSIEENKENIRLLNKNKDSFEEKYNRLQELSKDIIGYKNKFDNLEKDLVRLNEIDDGLESKEYT NTKLGELILDISKEKVGREENKEDYDAYIKSKGALDVLSSKTELQYKLNQVNNEVDVHVKNIKLAIDQDPHLSGDMSTAD LQARITDLKNKEEEFNQLKGFVQNKKALESQLISKKDDIGVSLNQIEILKNKIEASVYDKEKYEKVIYFYEVYERRYDEF AGELSEIKGQAKELIANVNVLAEKILTNYKFQQEYKNTTDYIDLLNHIRTLYSKNGIQKELRNRSRPVIQKYTKDFFDEF NFNYSDLTLDEDYEVTVFGPEGEASMSMVSGGEKIAIALALRLGITKAKAKGDLETILLDEPTIHLDSFRRHELINLLKD MTVLPQMIIVTHESQLENAADNLVKVEKNNGISKVSN
Sequences:
>Translated_917_residues MIFTKLTLNNFKSYGHEVIKFGDGITVIVGENGAGKSTILEAISFALFKQHTAKKIDDLVRNGSDENMYVDLEFVSNGKE YKIHREKTKSGLKSTLLKKTTSKGQFIPSCAGDKEVANEIQSILDIDSDLFLNAIYIRQGEIAELVDKTSSEKKQLIGKL LGLDSLEKAWKNLQPIISNYEKTQSELKGKLFSSEELKEEYDHKKALLGSLKEKGLDLEKQIEEVKEMKAEKQNEKTNME REKEIFDNFNNNLDAEKKRLESLENDKRTLQDNLDEIKKAEEQIARLEKFVKKLPLYLDFEKSVTSIQQLELDKQKIEKD LDSIATQEELLATKKEGYNKFLAADEQIEKLNNQKINLEKELATLTQLEKDKKQLLKSIEGNRNEIERFFSVTKDNLYDN GLSQDILTDVDNFTQLEEVTDNFSEEVSNKVKDLSLEIISKNEEIVKFKQAIETAQKPLDELGDVENKCPVCQSDINPQK KNELIDSYNNEIKINEKSIEENKENIRLLNKNKDSFEEKYNRLQELSKDIIGYKNKFDNLEKDLVRLNEIDDGLESKEYT NTKLGELILDISKEKVGREENKEDYDAYIKSKGALDVLSSKTELQYKLNQVNNEVDVHVKNIKLAIDQDPHLSGDMSTAD LQARITDLKNKEEEFNQLKGFVQNKKALESQLISKKDDIGVSLNQIEILKNKIEASVYDKEKYEKVIYFYEVYERRYDEF AGELSEIKGQAKELIANVNVLAEKILTNYKFQQEYKNTTDYIDLLNHIRTLYSKNGIQKELRNRSRPVIQKYTKDFFDEF NFNYSDLTLDEDYEVTVFGPEGEASMSMVSGGEKIAIALALRLGITKAKAKGDLETILLDEPTIHLDSFRRHELINLLKD MTVLPQMIIVTHESQLENAADNLVKVEKNNGISKVSN >Mature_917_residues MIFTKLTLNNFKSYGHEVIKFGDGITVIVGENGAGKSTILEAISFALFKQHTAKKIDDLVRNGSDENMYVDLEFVSNGKE YKIHREKTKSGLKSTLLKKTTSKGQFIPSCAGDKEVANEIQSILDIDSDLFLNAIYIRQGEIAELVDKTSSEKKQLIGKL LGLDSLEKAWKNLQPIISNYEKTQSELKGKLFSSEELKEEYDHKKALLGSLKEKGLDLEKQIEEVKEMKAEKQNEKTNME REKEIFDNFNNNLDAEKKRLESLENDKRTLQDNLDEIKKAEEQIARLEKFVKKLPLYLDFEKSVTSIQQLELDKQKIEKD LDSIATQEELLATKKEGYNKFLAADEQIEKLNNQKINLEKELATLTQLEKDKKQLLKSIEGNRNEIERFFSVTKDNLYDN GLSQDILTDVDNFTQLEEVTDNFSEEVSNKVKDLSLEIISKNEEIVKFKQAIETAQKPLDELGDVENKCPVCQSDINPQK KNELIDSYNNEIKINEKSIEENKENIRLLNKNKDSFEEKYNRLQELSKDIIGYKNKFDNLEKDLVRLNEIDDGLESKEYT NTKLGELILDISKEKVGREENKEDYDAYIKSKGALDVLSSKTELQYKLNQVNNEVDVHVKNIKLAIDQDPHLSGDMSTAD LQARITDLKNKEEEFNQLKGFVQNKKALESQLISKKDDIGVSLNQIEILKNKIEASVYDKEKYEKVIYFYEVYERRYDEF AGELSEIKGQAKELIANVNVLAEKILTNYKFQQEYKNTTDYIDLLNHIRTLYSKNGIQKELRNRSRPVIQKYTKDFFDEF NFNYSDLTLDEDYEVTVFGPEGEASMSMVSGGEKIAIALALRLGITKAKAKGDLETILLDEPTIHLDSFRRHELINLLKD MTVLPQMIIVTHESQLENAADNLVKVEKNNGISKVSN
Specific function: Involved in DNA double-strand break repair (DSBR). The rad50/mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of mre11 by unwinding and
COG id: COG0419
COG function: function code L; ATPase involved in DNA repair
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 zinc-hook domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR022982 - InterPro: IPR007517 - InterPro: IPR003395 - InterPro: IPR013134 [H]
Pfam domain/function: PF04423 Rad50_zn_hook; PF02463 SMC_N [H]
EC number: NA
Molecular weight: Translated: 105474; Mature: 105474
Theoretical pI: Translated: 4.81; Mature: 4.81
Prosite motif: PS51131 ZN_HOOK
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.0 %Met (Translated Protein) 1.3 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.0 %Met (Mature Protein) 1.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIFTKLTLNNFKSYGHEVIKFGDGITVIVGENGAGKSTILEAISFALFKQHTAKKIDDLV CEEEEEEHHHHHHHHHHHHEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH RNGSDENMYVDLEFVSNGKEYKIHREKTKSGLKSTLLKKTTSKGQFIPSCAGDKEVANEI HCCCCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH QSILDIDSDLFLNAIYIRQGEIAELVDKTSSEKKQLIGKLLGLDSLEKAWKNLQPIISNY HHHHCCCCHHHHEEEEECCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH EKTQSELKGKLFSSEELKEEYDHKKALLGSLKEKGLDLEKQIEEVKEMKAEKQNEKTNME HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHH REKEIFDNFNNNLDAEKKRLESLENDKRTLQDNLDEIKKAEEQIARLEKFVKKLPLYLDF HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC EKSVTSIQQLELDKQKIEKDLDSIATQEELLATKKEGYNKFLAADEQIEKLNNQKINLEK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHH ELATLTQLEKDKKQLLKSIEGNRNEIERFFSVTKDNLYDNGLSQDILTDVDNFTQLEEVT HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH DNFSEEVSNKVKDLSLEIISKNEEIVKFKQAIETAQKPLDELGDVENKCPVCQSDINPQK HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH KNELIDSYNNEIKINEKSIEENKENIRLLNKNKDSFEEKYNRLQELSKDIIGYKNKFDNL HHHHHHHCCCEEEEEHHHHHCCHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH EKDLVRLNEIDDGLESKEYTNTKLGELILDISKEKVGREENKEDYDAYIKSKGALDVLSS HHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCC KTELQYKLNQVNNEVDVHVKNIKLAIDQDPHLSGDMSTADLQARITDLKNKEEEFNQLKG CHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH FVQNKKALESQLISKKDDIGVSLNQIEILKNKIEASVYDKEKYEKVIYFYEVYERRYDEF HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AGELSEIKGQAKELIANVNVLAEKILTNYKFQQEYKNTTDYIDLLNHIRTLYSKNGIQKE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHH LRNRSRPVIQKYTKDFFDEFNFNYSDLTLDEDYEVTVFGPEGEASMSMVSGGEKIAIALA HHCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCHHHHHCCCCHHHHHHH LRLGITKAKAKGDLETILLDEPTIHLDSFRRHELINLLKDMTVLPQMIIVTHESQLENAA HHHCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHH DNLVKVEKNNGISKVSN HHHEEEECCCCCCCCCC >Mature Secondary Structure MIFTKLTLNNFKSYGHEVIKFGDGITVIVGENGAGKSTILEAISFALFKQHTAKKIDDLV CEEEEEEHHHHHHHHHHHHEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH RNGSDENMYVDLEFVSNGKEYKIHREKTKSGLKSTLLKKTTSKGQFIPSCAGDKEVANEI HCCCCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH QSILDIDSDLFLNAIYIRQGEIAELVDKTSSEKKQLIGKLLGLDSLEKAWKNLQPIISNY HHHHCCCCHHHHEEEEECCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH EKTQSELKGKLFSSEELKEEYDHKKALLGSLKEKGLDLEKQIEEVKEMKAEKQNEKTNME HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHH REKEIFDNFNNNLDAEKKRLESLENDKRTLQDNLDEIKKAEEQIARLEKFVKKLPLYLDF HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC EKSVTSIQQLELDKQKIEKDLDSIATQEELLATKKEGYNKFLAADEQIEKLNNQKINLEK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHH ELATLTQLEKDKKQLLKSIEGNRNEIERFFSVTKDNLYDNGLSQDILTDVDNFTQLEEVT HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH DNFSEEVSNKVKDLSLEIISKNEEIVKFKQAIETAQKPLDELGDVENKCPVCQSDINPQK HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH KNELIDSYNNEIKINEKSIEENKENIRLLNKNKDSFEEKYNRLQELSKDIIGYKNKFDNL HHHHHHHCCCEEEEEHHHHHCCHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH EKDLVRLNEIDDGLESKEYTNTKLGELILDISKEKVGREENKEDYDAYIKSKGALDVLSS HHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCC KTELQYKLNQVNNEVDVHVKNIKLAIDQDPHLSGDMSTADLQARITDLKNKEEEFNQLKG CHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH FVQNKKALESQLISKKDDIGVSLNQIEILKNKIEASVYDKEKYEKVIYFYEVYERRYDEF HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AGELSEIKGQAKELIANVNVLAEKILTNYKFQQEYKNTTDYIDLLNHIRTLYSKNGIQKE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHH LRNRSRPVIQKYTKDFFDEFNFNYSDLTLDEDYEVTVFGPEGEASMSMVSGGEKIAIALA HHCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCHHHHHCCCCHHHHHHH LRLGITKAKAKGDLETILLDEPTIHLDSFRRHELINLLKDMTVLPQMIIVTHESQLENAA HHHCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHH DNLVKVEKNNGISKVSN HHHEEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ribo- or deoxyribonucleic acids [C]
Specific reaction: ribo- or deoxyribonucleic acids = 5'-phosphomonoesters [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]