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The map label for this gene is fabD [H]

Identifier: 148381539

GI number: 148381539

Start: 3844104

End: 3845048

Strand: Reverse

Name: fabD [H]

Synonym: CBO3601

Alternate gene names: 148381539

Gene position: 3845048-3844104 (Counterclockwise)

Preceding gene: 148381540

Following gene: 148381538

Centisome position: 98.92

GC content: 30.79

Gene sequence:

>945_bases
ATGTCAAAGATAGCTTTTATATTCTCAGGTCAAGGAGCTCAATATGTAGGTATGGGGAAAGATTTATATAAAAATATTCC
CGAATGTAGAAAAATATTTGAAATAGCAGAGGAAGAACTACAAATACCTTTAACTAAAATATGTTTTCAAGGTCCAAAGG
ATGAAATAGATAAAACAGAAAATACCCAACCAGCAATACTAACTCTTAGTATTGCTGCTATGAAAGCATTAGAAAAGTAC
GGTATAAAACCGGATGTTACGGCAGGGCTAAGTTTAGGTGAATATTCAGCTTTGGTTTGTAGTAAAGTTATAGATTTTAA
AGAAGCAGTTTCTTTGGTAAGAAAAAGAGGGCAATATATGGAGCATGCAGTACCTAATGGCGTGGGTACTATGGCAGCTA
TAATAGGTCTTAAAAAAGAAAAAGTTAAGGAAATTTGCGATGATTTAAAAAAGGTTGGAATAGTTGAAATAGCAAATATT
AATTGCCCAGGGCAGATTGTTATTTCTGGAGAAATAAATGCAGTGGAAAAGGCCTGTGAAATGGCAAAAGAAAAAAGAGC
TTTAAAGTGTGTAAACCTTAGTGTTAGTGGGCCATTTCATAGTAGTATGTTAAAAGAAGCTGGAGAAAATTTATATGAAG
AGTTACAAAAAATACGGTTTAACTCTATAGAAGTTCCATTTATAACAAATGTAACAGGAGATTTTGTTATAAATACTAGT
GAAATAAAAGATTTATTAAAGAAGCAGGTTATGAGTACTGTACTTTGGGAAGGGTCTATAAAAACAATGATAGATTTTGG
GGTAGATACCTTTATAGAAATAGGTCCTTCAAAGGTTTTATCAGGTTTTGTTAAGAAAATAGATAGGAAAGTAAATATAT
TAAATGTAGAAGATATAGATTCCCTTAATAAAACAATAGAAAAATTAAAAACAATAAATAGTTAG

Upstream 100 bases:

>100_bases
TTATAAATAAGGAACAAACTTGTAGTGAAATTATAAATGAAATATTTGATGAAGCATATACACTATTAGATTATAAATAA
TATTTATTTTGGAGGATATT

Downstream 100 bases:

>100_bases
GAGAGTTGGGTAATAATATGAAATGTTTAGAAGGTAGAACCGCAATAGTAACAGGAGCAAGTAGAGGTATAGGAAGAGCA
ATAGCTAAAAAATTAGCGTC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSKIAFIFSGQGAQYVGMGKDLYKNIPECRKIFEIAEEELQIPLTKICFQGPKDEIDKTENTQPAILTLSIAAMKALEKY
GIKPDVTAGLSLGEYSALVCSKVIDFKEAVSLVRKRGQYMEHAVPNGVGTMAAIIGLKKEKVKEICDDLKKVGIVEIANI
NCPGQIVISGEINAVEKACEMAKEKRALKCVNLSVSGPFHSSMLKEAGENLYEELQKIRFNSIEVPFITNVTGDFVINTS
EIKDLLKKQVMSTVLWEGSIKTMIDFGVDTFIEIGPSKVLSGFVKKIDRKVNILNVEDIDSLNKTIEKLKTINS

Sequences:

>Translated_314_residues
MSKIAFIFSGQGAQYVGMGKDLYKNIPECRKIFEIAEEELQIPLTKICFQGPKDEIDKTENTQPAILTLSIAAMKALEKY
GIKPDVTAGLSLGEYSALVCSKVIDFKEAVSLVRKRGQYMEHAVPNGVGTMAAIIGLKKEKVKEICDDLKKVGIVEIANI
NCPGQIVISGEINAVEKACEMAKEKRALKCVNLSVSGPFHSSMLKEAGENLYEELQKIRFNSIEVPFITNVTGDFVINTS
EIKDLLKKQVMSTVLWEGSIKTMIDFGVDTFIEIGPSKVLSGFVKKIDRKVNILNVEDIDSLNKTIEKLKTINS
>Mature_313_residues
SKIAFIFSGQGAQYVGMGKDLYKNIPECRKIFEIAEEELQIPLTKICFQGPKDEIDKTENTQPAILTLSIAAMKALEKYG
IKPDVTAGLSLGEYSALVCSKVIDFKEAVSLVRKRGQYMEHAVPNGVGTMAAIIGLKKEKVKEICDDLKKVGIVEIANIN
CPGQIVISGEINAVEKACEMAKEKRALKCVNLSVSGPFHSSMLKEAGENLYEELQKIRFNSIEVPFITNVTGDFVINTSE
IKDLLKKQVMSTVLWEGSIKTMIDFGVDTFIEIGPSKVLSGFVKKIDRKVNILNVEDIDSLNKTIEKLKTINS

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=304, Percent_Identity=29.2763157894737, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=36.697247706422, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=42.7083333333333, Blast_Score=227, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=29.3918918918919, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=28.2312925170068, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=33.6633663366337, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34658; Mature: 34527

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIAFIFSGQGAQYVGMGKDLYKNIPECRKIFEIAEEELQIPLTKICFQGPKDEIDKTE
CCCEEEEEECCCCEEECCCHHHHHCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHCCCC
NTQPAILTLSIAAMKALEKYGIKPDVTAGLSLGEYSALVCSKVIDFKEAVSLVRKRGQYM
CCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHAVPNGVGTMAAIIGLKKEKVKEICDDLKKVGIVEIANINCPGQIVISGEINAVEKACE
HHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHHHHHHHH
MAKEKRALKCVNLSVSGPFHSSMLKEAGENLYEELQKIRFNSIEVPFITNVTGDFVINTS
HHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEHH
EIKDLLKKQVMSTVLWEGSIKTMIDFGVDTFIEIGPSKVLSGFVKKIDRKVNILNVEDID
HHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHCCHHHHHHHHHHHHHCCCEEECHHHHH
SLNKTIEKLKTINS
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SKIAFIFSGQGAQYVGMGKDLYKNIPECRKIFEIAEEELQIPLTKICFQGPKDEIDKTE
CCEEEEEECCCCEEECCCHHHHHCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHCCCC
NTQPAILTLSIAAMKALEKYGIKPDVTAGLSLGEYSALVCSKVIDFKEAVSLVRKRGQYM
CCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHAVPNGVGTMAAIIGLKKEKVKEICDDLKKVGIVEIANINCPGQIVISGEINAVEKACE
HHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHHHHHHHH
MAKEKRALKCVNLSVSGPFHSSMLKEAGENLYEELQKIRFNSIEVPFITNVTGDFVINTS
HHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEHH
EIKDLLKKQVMSTVLWEGSIKTMIDFGVDTFIEIGPSKVLSGFVKKIDRKVNILNVEDID
HHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHCCHHHHHHHHHHHHHCCCEEECHHHHH
SLNKTIEKLKTINS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]