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The map label for this gene is fabZ

Identifier: 148381535

GI number: 148381535

Start: 3841148

End: 3841582

Strand: Reverse

Name: fabZ

Synonym: CBO3597

Alternate gene names: 148381535

Gene position: 3841582-3841148 (Counterclockwise)

Preceding gene: 148381536

Following gene: 148381534

Centisome position: 98.83

GC content: 31.72

Gene sequence:

>435_bases
ATGGAGAAATTTTTAGATATAAATGAAATAAAAAAAATTATTCCGCACAGATATCCATTTTTATTAGTAGATAAAATAAC
TGAATTAGAAGAGGGAAAAAGTGCAGTTGGATATAAAAATGTTACAGCTAATGAATACTTTTTTAATGGGCATTTTCCCG
AAGAACCAGTAATGCCTGGGGTTCTGATTATAGAAGCTTTAGCACAGGTCGGAGCTGTTGCTATTTTAAGTAAAGAAGAG
TTTAAAGGAAAAATAGCTTATTTTGGAGGTATAAATAAAGCTAAGTTCAGAAAAAAGGTAGTACCAGGAGATGTTTTAAA
ACTTAGTATAGATCTTACTAAAATAAAAGGCGTTGCAGGAGTAGGTAAGGCCGTAGCTACTGTAGATGGGAAAGTAGCTG
CAGAAGCAGAATTATTATTTGTAATAGGAAAATAA

Upstream 100 bases:

>100_bases
GGAGAAATAGTAGAGGTATTGGTAGAGAATGAGCAAATGGTTCAATATGGAGAAGTTTTATTTAAGATAAAGCCACTATA
ATGAAAAAGGAGAATTTTTA

Downstream 100 bases:

>100_bases
ATCTATAAAAATAGAAGGGGAGAAGATAGCAGTGTTTAAGAAAATACTTGTGGCTAATAGAGGTGAGATTGCGGTTAGAA
TAATTAGAGCTTGTAGAGAA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MEKFLDINEIKKIIPHRYPFLLVDKITELEEGKSAVGYKNVTANEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEE
FKGKIAYFGGINKAKFRKKVVPGDVLKLSIDLTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK

Sequences:

>Translated_144_residues
MEKFLDINEIKKIIPHRYPFLLVDKITELEEGKSAVGYKNVTANEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEE
FKGKIAYFGGINKAKFRKKVVPGDVLKLSIDLTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK
>Mature_144_residues
MEKFLDINEIKKIIPHRYPFLLVDKITELEEGKSAVGYKNVTANEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEE
FKGKIAYFGGINKAKFRKKVVPGDVLKLSIDLTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=137, Percent_Identity=45.985401459854, Blast_Score=125, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_CLOB1 (A7FPN7)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385909.1
- ProteinModelPortal:   A7FPN7
- SMR:   A7FPN7
- STRING:   A7FPN7
- GeneID:   5397218
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3677
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   CBOT441770:CLB_3677-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 15690; Mature: 15690

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: ACT_SITE 51-51

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKFLDINEIKKIIPHRYPFLLVDKITELEEGKSAVGYKNVTANEYFFNGHFPEEPVMPG
CCCCCCHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCH
VLIIEALAQVGAVAILSKEEFKGKIAYFGGINKAKFRKKVVPGDVLKLSIDLTKIKGVAG
HHHHHHHHHHCEEEEEEHHHHCCEEEEECCCCHHHHHHHCCCCCEEEEEEEHHHHCCCCC
VGKAVATVDGKVAAEAELLFVIGK
CCCEEEECCCCEECCEEEEEEECC
>Mature Secondary Structure
MEKFLDINEIKKIIPHRYPFLLVDKITELEEGKSAVGYKNVTANEYFFNGHFPEEPVMPG
CCCCCCHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCH
VLIIEALAQVGAVAILSKEEFKGKIAYFGGINKAKFRKKVVPGDVLKLSIDLTKIKGVAG
HHHHHHHHHHCEEEEEEHHHHCCEEEEECCCCHHHHHHHCCCCCEEEEEEEHHHHCCCCC
VGKAVATVDGKVAAEAELLFVIGK
CCCEEEECCCCEECCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA