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The map label for this gene is glmM

Identifier: 148381360

GI number: 148381360

Start: 3660438

End: 3661787

Strand: Reverse

Name: glmM

Synonym: CBO3420

Alternate gene names: 148381360

Gene position: 3661787-3660438 (Counterclockwise)

Preceding gene: 148381361

Following gene: 148381359

Centisome position: 94.21

GC content: 31.63

Gene sequence:

>1350_bases
ATGGGTAGAATGTTCGGAACAGATGGAGTCAGAGGAATAGCTAATAAGGAATTAACAGCAGACTTAGCATATAAATTAGG
TAAAGCAGGAGCTTTTATATTAACAGAAGGAACACATAGATCTAAGATACTTGTAGGTATGGATACAAGAATATCAGGGG
ACATGCTAGAGAGTGCTTTAGTAGCAGGTATATTATCTGTGGGAGCAGAAGCTATTTGTGTAGGTGTAATACCAACACCA
GCAATAGCTTACTTAACAAGAAAGTATAATGCGGATGCAGGGGTTGTTATTTCAGCATCACATAATCCAGTAGAATACAA
TGGTATAAAGTTTTTTAATAAAAATGGATACAAATTATCCGATGAATTAGAAGATAGTATACAAGCATTAATAAGAGATG
ATTTTAAGGATGTTCCAGTTTTAACTGGAGAAAATATAGGAAGAAAGATTGAAGAAGATGGAGAGGCTATAAGAGATTAC
ATAGATTTTGCTAAATCAACTATAAAGGGTGATTTGAAAGGATTAAAAGTAGCTTTAGATTGTGCTAATGGAGCATCATA
TATAACATCTGTAGAAGCTTTTAAAGAATTAGGAGCAGAAGTTCATGTTATAAACAACAAACCTGATGGTATAAATATAA
ATAGAAACTCTGGCTCAACACACCCAGAAGATCTTATGGAGTATGTAGTTAAAAATAATTGCCACATGGGATTAGCTTTT
GATGGAGATGCGGATAGATGTCTAGCCATAGATGAAAAAGGTAATTTGATAAATGGAGACTTTATATTAGCCATTTGTGG
TAAGGAATTAAAAAAACAAGGTAGATTAAAGAAAAATACAATAGTAGTTACTGTAATGAGTAATCTTGGATTAGATATAG
CTATGAAAAAAGAAGAAATAAATACTATAAAAACAAAAGTTGGAGATAGATATGTCCTAGAAGAAATGCTTAAAAATGAT
TATGCAATAGGTGGAGAACAATCAGGACATATTATATTCTCAGATTATAACACTACAGGGGATGGACTTGTAACTGCTCT
ACAATTAGCTCATATAGTAAAAGAAAGTGGTAAGACTTTTTCAGAACTATGTTCTATAATGAAAGAACTACCACAAGTTT
TAGTTAATGCTAAAGTTCCTAATGATCAAAAAGATATTTATTTGAAGGATGAAGAAATAAAATCTGAAATAGATACAATT
ACAAAAAATTTAGATGGCTCAGGAAGAGTGCTTATAAGACCTTCTGGTACAGAGCCTTTAGTAAGAGTAATGCTTGAAGG
GGAAAACCAAAAGGAAATTGATAAATTAGCACATGGCTTAGCTAAATTAATAGAGAATAAAGTAAAATAA

Upstream 100 bases:

>100_bases
ACTGGCTTTTTATATTTTTCAATTATGTTTCCTATTGTTAGAATTAGTAAACTATAATATAATATCTATGTGTATTTAAA
AAATAGGAGTGATGAATTAC

Downstream 100 bases:

>100_bases
TAGGATTAATTTATATTTTTAAAACATAAGGGTAATTTATAATTATTAGGTTAATTATAAATTACCCTTATGTTTTTTAT
TATAATAAATAAAATTAAAA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MGRMFGTDGVRGIANKELTADLAYKLGKAGAFILTEGTHRSKILVGMDTRISGDMLESALVAGILSVGAEAICVGVIPTP
AIAYLTRKYNADAGVVISASHNPVEYNGIKFFNKNGYKLSDELEDSIQALIRDDFKDVPVLTGENIGRKIEEDGEAIRDY
IDFAKSTIKGDLKGLKVALDCANGASYITSVEAFKELGAEVHVINNKPDGININRNSGSTHPEDLMEYVVKNNCHMGLAF
DGDADRCLAIDEKGNLINGDFILAICGKELKKQGRLKKNTIVVTVMSNLGLDIAMKKEEINTIKTKVGDRYVLEEMLKND
YAIGGEQSGHIIFSDYNTTGDGLVTALQLAHIVKESGKTFSELCSIMKELPQVLVNAKVPNDQKDIYLKDEEIKSEIDTI
TKNLDGSGRVLIRPSGTEPLVRVMLEGENQKEIDKLAHGLAKLIENKVK

Sequences:

>Translated_449_residues
MGRMFGTDGVRGIANKELTADLAYKLGKAGAFILTEGTHRSKILVGMDTRISGDMLESALVAGILSVGAEAICVGVIPTP
AIAYLTRKYNADAGVVISASHNPVEYNGIKFFNKNGYKLSDELEDSIQALIRDDFKDVPVLTGENIGRKIEEDGEAIRDY
IDFAKSTIKGDLKGLKVALDCANGASYITSVEAFKELGAEVHVINNKPDGININRNSGSTHPEDLMEYVVKNNCHMGLAF
DGDADRCLAIDEKGNLINGDFILAICGKELKKQGRLKKNTIVVTVMSNLGLDIAMKKEEINTIKTKVGDRYVLEEMLKND
YAIGGEQSGHIIFSDYNTTGDGLVTALQLAHIVKESGKTFSELCSIMKELPQVLVNAKVPNDQKDIYLKDEEIKSEIDTI
TKNLDGSGRVLIRPSGTEPLVRVMLEGENQKEIDKLAHGLAKLIENKVK
>Mature_448_residues
GRMFGTDGVRGIANKELTADLAYKLGKAGAFILTEGTHRSKILVGMDTRISGDMLESALVAGILSVGAEAICVGVIPTPA
IAYLTRKYNADAGVVISASHNPVEYNGIKFFNKNGYKLSDELEDSIQALIRDDFKDVPVLTGENIGRKIEEDGEAIRDYI
DFAKSTIKGDLKGLKVALDCANGASYITSVEAFKELGAEVHVINNKPDGININRNSGSTHPEDLMEYVVKNNCHMGLAFD
GDADRCLAIDEKGNLINGDFILAICGKELKKQGRLKKNTIVVTVMSNLGLDIAMKKEEINTIKTKVGDRYVLEEMLKNDY
AIGGEQSGHIIFSDYNTTGDGLVTALQLAHIVKESGKTFSELCSIMKELPQVLVNAKVPNDQKDIYLKDEEIKSEIDTIT
KNLDGSGRVLIRPSGTEPLVRVMLEGENQKEIDKLAHGLAKLIENKVK

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=43.0493273542601, Blast_Score=334, Evalue=8e-93,
Organism=Escherichia coli, GI1788361, Length=448, Percent_Identity=30.5803571428571, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI17864244, Length=358, Percent_Identity=25.6983240223464, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_CLOB1 (A7FZ14)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385737.1
- ProteinModelPortal:   A7FZ14
- SMR:   A7FZ14
- STRING:   A7FZ14
- GeneID:   5394742
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3477
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14316
- BioCyc:   CBOT441770:CLB_3477-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48894; Mature: 48762

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 100-100

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRMFGTDGVRGIANKELTADLAYKLGKAGAFILTEGTHRSKILVGMDTRISGDMLESAL
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHH
VAGILSVGAEAICVGVIPTPAIAYLTRKYNADAGVVISASHNPVEYNGIKFFNKNGYKLS
HHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCEEEECCCCCEEECCEEEECCCCCEEH
DELEDSIQALIRDDFKDVPVLTGENIGRKIEEDGEAIRDYIDFAKSTIKGDLKGLKVALD
HHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
CANGASYITSVEAFKELGAEVHVINNKPDGININRNSGSTHPEDLMEYVVKNNCHMGLAF
ECCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEE
DGDADRCLAIDEKGNLINGDFILAICGKELKKQGRLKKNTIVVTVMSNLGLDIAMKKEEI
CCCCCCEEEEECCCCEECCCEEEEECCHHHHHCCCCCCCEEEEEEHHHCCCEEEECHHHH
NTIKTKVGDRYVLEEMLKNDYAIGGEQSGHIIFSDYNTTGDGLVTALQLAHIVKESGKTF
HHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCH
SELCSIMKELPQVLVNAKVPNDQKDIYLKDEEIKSEIDTITKNLDGSGRVLIRPSGTEPL
HHHHHHHHHHHHHHEECCCCCCCCCEEECHHHHHHHHHHHHHCCCCCCEEEEECCCCCHH
VRVMLEGENQKEIDKLAHGLAKLIENKVK
HHEEECCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRMFGTDGVRGIANKELTADLAYKLGKAGAFILTEGTHRSKILVGMDTRISGDMLESAL
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHH
VAGILSVGAEAICVGVIPTPAIAYLTRKYNADAGVVISASHNPVEYNGIKFFNKNGYKLS
HHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCEEEECCCCCEEECCEEEECCCCCEEH
DELEDSIQALIRDDFKDVPVLTGENIGRKIEEDGEAIRDYIDFAKSTIKGDLKGLKVALD
HHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
CANGASYITSVEAFKELGAEVHVINNKPDGININRNSGSTHPEDLMEYVVKNNCHMGLAF
ECCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEE
DGDADRCLAIDEKGNLINGDFILAICGKELKKQGRLKKNTIVVTVMSNLGLDIAMKKEEI
CCCCCCEEEEECCCCEECCCEEEEECCHHHHHCCCCCCCEEEEEEHHHCCCEEEECHHHH
NTIKTKVGDRYVLEEMLKNDYAIGGEQSGHIIFSDYNTTGDGLVTALQLAHIVKESGKTF
HHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCH
SELCSIMKELPQVLVNAKVPNDQKDIYLKDEEIKSEIDTITKNLDGSGRVLIRPSGTEPL
HHHHHHHHHHHHHHEECCCCCCCCCEEECHHHHHHHHHHHHHCCCCCCEEEEECCCCCHH
VRVMLEGENQKEIDKLAHGLAKLIENKVK
HHEEECCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA