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The map label for this gene is infC [H]

Identifier: 148381086

GI number: 148381086

Start: 3337226

End: 3337747

Strand: Reverse

Name: infC [H]

Synonym: CBO3137

Alternate gene names: 148381086

Gene position: 3337747-3337226 (Counterclockwise)

Preceding gene: 148381087

Following gene: 148381085

Centisome position: 85.87

GC content: 30.84

Gene sequence:

>522_bases
GTGAAGATTATTAACAAAAACTATCTTATGAATGAGCAAATCCGTGAAAGAGAAGTAAGACTTGTAGGTAGCGAGGGAGA
ACAATTAGGAGTAGTGTCTTCAAGTGAGGCGCAAAAGCTTGCAGATGAAAAGGAACTAGACTTAGTACTTATAGCTCCAA
CTGCAAAACCACCAGTTTGTAAAATAATGAATTATGGTAAATTCTTATATGAACAAACTAAAAAAGACAAAGAAGCTAAA
AAGAATCAAAAGGTTATAAACATAAAAGAAGTTAGACTAAGCCCAACTATAGAAGCACATGACATAGAAATTAAAGCTAA
TAATGCTAGAAAATTTTTAAATGCAGGAAATAAAGTTAAAGTAACTGTTAGATTCAGAGGTAGAGAAGCTGATTATTCCT
TTAAAGGAAATAAAATATTAAAATCCTTTTATGAAAAAGTAGAAGAACTTAGTGTTATGGAAAAAGCACCTAAACTAGAA
GGAAGAAATATGATAATGATATTAGCGCCAAGAAAAGCGTAA

Upstream 100 bases:

>100_bases
TAAATTTAATTTGTATTATTGTTTATGAAGACGGCTTATGCCGTCTTTTATTTATTATACATGAAAATTGTTAAGTGTTT
TCGGTCTAATATTTTTGGAG

Downstream 100 bases:

>100_bases
TAACGAGGGGAGGAAATCACAATGCCAAAAATGAAAACAAAAAGGGCTGCAGCAAAGAGATTTAAAGTAACTGGAACAGG
TAAGTTAAAGAGAGCTAAAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKIINKNYLMNEQIREREVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVCKIMNYGKFLYEQTKKDKEAK
KNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVKVTVRFRGREADYSFKGNKILKSFYEKVEELSVMEKAPKLE
GRNMIMILAPRKA

Sequences:

>Translated_173_residues
MKIINKNYLMNEQIREREVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVCKIMNYGKFLYEQTKKDKEAK
KNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVKVTVRFRGREADYSFKGNKILKSFYEKVEELSVMEKAPKLE
GRNMIMILAPRKA
>Mature_173_residues
MKIINKNYLMNEQIREREVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVCKIMNYGKFLYEQTKKDKEAK
KNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVKVTVRFRGREADYSFKGNKILKSFYEKVEELSVMEKAPKLE
GRNMIMILAPRKA

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=50.609756097561, Blast_Score=149, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19810; Mature: 19810

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIINKNYLMNEQIREREVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVC
CCCCCCCCCCCHHHHHCEEEEECCCCCEEEEEECCHHHHHCCCCCCCEEEEECCCCCCHH
KIMNYGKFLYEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVK
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEEEEEECCHHHHHCCCCEEE
VTVRFRGREADYSFKGNKILKSFYEKVEELSVMEKAPKLEGRNMIMILAPRKA
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKIINKNYLMNEQIREREVRLVGSEGEQLGVVSSSEAQKLADEKELDLVLIAPTAKPPVC
CCCCCCCCCCCHHHHHCEEEEECCCCCEEEEEECCHHHHHCCCCCCCEEEEECCCCCCHH
KIMNYGKFLYEQTKKDKEAKKNQKVINIKEVRLSPTIEAHDIEIKANNARKFLNAGNKVK
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEEEEEECCHHHHHCCCCEEE
VTVRFRGREADYSFKGNKILKSFYEKVEELSVMEKAPKLEGRNMIMILAPRKA
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]