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The map label for this gene is yxdK [H]

Identifier: 148379371

GI number: 148379371

Start: 1520968

End: 1521945

Strand: Direct

Name: yxdK [H]

Synonym: CBO1395

Alternate gene names: 148379371

Gene position: 1520968-1521945 (Clockwise)

Preceding gene: 148379370

Following gene: 148379372

Centisome position: 39.13

GC content: 25.05

Gene sequence:

>978_bases
ATGAAAATTTTTATCAAAAATAATAAGGGCGTCATAATATTATTTATACTAAATTTTATGATACTATTTAGCTTATACAA
TCTAATGGGTGGATTTGAGGACTTTAATAACTTTATTTATTTTATGTTATTAAGCTTATTTAATTTATTGGTTTATTTAA
TATTAAAATACTTAAATGAAAGAAAAATGTATAAGAGTTTAGAGAAAAAACCTGAAATATTTGAAGATTGTTTAAATTCC
TTTGGAGATTCTACTTTAGGGAAAAACTTAAATGGATATACCGGCGAACTATATAGTATTTATAAATATCATATGCATGA
AAATATAAAAAAGCAAACAGAACATTTAAATTTTATAAATCAATGGGTGCACCAAATGAAGACACCTCTATCTGTAATAA
AGCTAATAATTCAAGAAAATGTGGAACAACAATGTATAAAAGATATCAAAGAAGAAGTAGAAAAATTAGAAGAAGGATTA
AATATCGCTCTTTACAATGCTAGGCTAGAAAATTTTCATAATGATTTTAATGTGGCAGAGTTCGATTTGAAAGAATTGGT
TTTAGATAGAGTTAACTATAATAAAAAATTGTTTATAAAAAATGGAGTTTTCCCAAAAGTAGAAATGAATAATATTAAAA
TTAAATCAGATAGAAAATGGATATCTTTTATATTAGATCAGATTATAATTAATGGTGTAAAATACTCAAAGGGGAAAGGA
AAACTGATAGAAATAAAAGCAGGAGAGCAGCAAAAAAGAAGTTATATATATATAAGAGATGAAGGCATTGGTATACCTAA
AAAAGATATAAACAGAGTAATAGAACCTTTTTATACAGGAGAAAATGGCAGGACTTTTGGAGAATCTACAGGCATGGGGC
TCTATATAACAAATGAAGTTTGTAAAAAATTAAACCATGAATTAGAGATACAATCTAATGAAGGAGAAGGCACTAAGATT
ACAATATATTTTAATTAA

Upstream 100 bases:

>100_bases
GCAAGACTTAGAAAAAAATTATTAGATTTAGGTATAAAAGATTCTATAGAGACTGTAAGAGGGGCAGGATATAGATTGCA
TGTAACTTGGAGGAAATAGA

Downstream 100 bases:

>100_bases
TAAAATGGTAGCTTACTTTAAAATAATTAATATTATTTTTGATAGTTAGGAGAAATATATGGATATTATTGAATTAAAAG
AAGTTTATAAAATATATGGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MKIFIKNNKGVIILFILNFMILFSLYNLMGGFEDFNNFIYFMLLSLFNLLVYLILKYLNERKMYKSLEKKPEIFEDCLNS
FGDSTLGKNLNGYTGELYSIYKYHMHENIKKQTEHLNFINQWVHQMKTPLSVIKLIIQENVEQQCIKDIKEEVEKLEEGL
NIALYNARLENFHNDFNVAEFDLKELVLDRVNYNKKLFIKNGVFPKVEMNNIKIKSDRKWISFILDQIIINGVKYSKGKG
KLIEIKAGEQQKRSYIYIRDEGIGIPKKDINRVIEPFYTGENGRTFGESTGMGLYITNEVCKKLNHELEIQSNEGEGTKI
TIYFN

Sequences:

>Translated_325_residues
MKIFIKNNKGVIILFILNFMILFSLYNLMGGFEDFNNFIYFMLLSLFNLLVYLILKYLNERKMYKSLEKKPEIFEDCLNS
FGDSTLGKNLNGYTGELYSIYKYHMHENIKKQTEHLNFINQWVHQMKTPLSVIKLIIQENVEQQCIKDIKEEVEKLEEGL
NIALYNARLENFHNDFNVAEFDLKELVLDRVNYNKKLFIKNGVFPKVEMNNIKIKSDRKWISFILDQIIINGVKYSKGKG
KLIEIKAGEQQKRSYIYIRDEGIGIPKKDINRVIEPFYTGENGRTFGESTGMGLYITNEVCKKLNHELEIQSNEGEGTKI
TIYFN
>Mature_325_residues
MKIFIKNNKGVIILFILNFMILFSLYNLMGGFEDFNNFIYFMLLSLFNLLVYLILKYLNERKMYKSLEKKPEIFEDCLNS
FGDSTLGKNLNGYTGELYSIYKYHMHENIKKQTEHLNFINQWVHQMKTPLSVIKLIIQENVEQQCIKDIKEEVEKLEEGL
NIALYNARLENFHNDFNVAEFDLKELVLDRVNYNKKLFIKNGVFPKVEMNNIKIKSDRKWISFILDQIIINGVKYSKGKG
KLIEIKAGEQQKRSYIYIRDEGIGIPKKDINRVIEPFYTGENGRTFGESTGMGLYITNEVCKKLNHELEIQSNEGEGTKI
TIYFN

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789808, Length=294, Percent_Identity=21.7687074829932, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38208; Mature: 38208

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFIKNNKGVIILFILNFMILFSLYNLMGGFEDFNNFIYFMLLSLFNLLVYLILKYLNE
CEEEEECCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKMYKSLEKKPEIFEDCLNSFGDSTLGKNLNGYTGELYSIYKYHMHENIKKQTEHLNFIN
HHHHHHHHCCHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QWVHQMKTPLSVIKLIIQENVEQQCIKDIKEEVEKLEEGLNIALYNARLENFHNDFNVAE
HHHHHHHCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCHHH
FDLKELVLDRVNYNKKLFIKNGVFPKVEMNNIKIKSDRKWISFILDQIIINGVKYSKGKG
HHHHHHHHHHHCCCCEEEEECCCCCCEECCCEEEECCHHHHHHHHHHHHHCCCCCCCCCC
KLIEIKAGEQQKRSYIYIRDEGIGIPKKDINRVIEPFYTGENGRTFGESTGMGLYITNEV
CEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEHHH
CKKLNHELEIQSNEGEGTKITIYFN
HHHCCCCEEEECCCCCCCEEEEEEC
>Mature Secondary Structure
MKIFIKNNKGVIILFILNFMILFSLYNLMGGFEDFNNFIYFMLLSLFNLLVYLILKYLNE
CEEEEECCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKMYKSLEKKPEIFEDCLNSFGDSTLGKNLNGYTGELYSIYKYHMHENIKKQTEHLNFIN
HHHHHHHHCCHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QWVHQMKTPLSVIKLIIQENVEQQCIKDIKEEVEKLEEGLNIALYNARLENFHNDFNVAE
HHHHHHHCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCHHH
FDLKELVLDRVNYNKKLFIKNGVFPKVEMNNIKIKSDRKWISFILDQIIINGVKYSKGKG
HHHHHHHHHHHCCCCEEEEECCCCCCEECCCEEEECCHHHHHHHHHHHHHCCCCCCCCCC
KLIEIKAGEQQKRSYIYIRDEGIGIPKKDINRVIEPFYTGENGRTFGESTGMGLYITNEV
CEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEHHH
CKKLNHELEIQSNEGEGTKITIYFN
HHHCCCCEEEECCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]