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The map label for this gene is yciA [H]

Identifier: 148361143

GI number: 148361143

Start: 3373862

End: 3374242

Strand: Reverse

Name: yciA [H]

Synonym: LPC_3117

Alternate gene names: 148361143

Gene position: 3374242-3373862 (Counterclockwise)

Preceding gene: 148361144

Following gene: 148361142

Centisome position: 94.35

GC content: 41.73

Gene sequence:

>381_bases
ATGCAAACACCTAAAGGAGAGTTGACTATCCAAACTTTGGCCATGCCTTTAAATACTAATGCCAATGGCGATATATTTGG
CGGATGGATAGTCTCCCAAATGGATTTGGCAGCAGGTGTTTTGGCAAAGAGAATTTCCCATGGGCGTGTCGCTACCGTTG
CGATTAATTCAATGACTTTTTTAAAACCTGTGCATGTAGGCGATGTAGTGAGCTGCCACGTTGAATTAGTGAAAGTGGGT
AATACCTCTATGACTATTCGGGTTGAGGTATGGGCTTACTCATCGATCAAAATGGAAAAATACCAGGTTACTGAAGGGAT
ATTTGTTTTTGTTGCGATTGATGAAAATGGAAAGCCGAGGCAGGTACCAAAAACACAATGA

Upstream 100 bases:

>100_bases
AACCAGATAAGATAAAAAAACCGGAGCCAGTCAAAAAAACCGTATTTAATACAGCCATGGCCGATGCTTTAGCCAAACTA
AAACGTGGTGGAGAATAGGG

Downstream 100 bases:

>100_bases
CTAATAAAACTCAAGAGTTGCAGCGAGTAATTGCTGATATGGCTGTATTGATTGAGCAAGATGCAGAGCCTGACCCTCAA
TTGTATGCCTTTTTTTTTCA

Product: acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MQTPKGELTIQTLAMPLNTNANGDIFGGWIVSQMDLAAGVLAKRISHGRVATVAINSMTFLKPVHVGDVVSCHVELVKVG
NTSMTIRVEVWAYSSIKMEKYQVTEGIFVFVAIDENGKPRQVPKTQ

Sequences:

>Translated_126_residues
MQTPKGELTIQTLAMPLNTNANGDIFGGWIVSQMDLAAGVLAKRISHGRVATVAINSMTFLKPVHVGDVVSCHVELVKVG
NTSMTIRVEVWAYSSIKMEKYQVTEGIFVFVAIDENGKPRQVPKTQ
>Mature_126_residues
MQTPKGELTIQTLAMPLNTNANGDIFGGWIVSQMDLAAGVLAKRISHGRVATVAINSMTFLKPVHVGDVVSCHVELVKVG
NTSMTIRVEVWAYSSIKMEKYQVTEGIFVFVAIDENGKPRQVPKTQ

Specific function: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA [H]

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1787506, Length=123, Percent_Identity=53.6585365853659, Blast_Score=147, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 13758; Mature: 13758

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTPKGELTIQTLAMPLNTNANGDIFGGWIVSQMDLAAGVLAKRISHGRVATVAINSMTF
CCCCCCCEEEEEEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCEEE
LKPVHVGDVVSCHVELVKVGNTSMTIRVEVWAYSSIKMEKYQVTEGIFVFVAIDENGKPR
EEEECCCCEEEEEEEEEEECCCEEEEEEEEEEECCEEEEEEEECCCEEEEEEECCCCCCC
QVPKTQ
CCCCCC
>Mature Secondary Structure
MQTPKGELTIQTLAMPLNTNANGDIFGGWIVSQMDLAAGVLAKRISHGRVATVAINSMTF
CCCCCCCEEEEEEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCEEE
LKPVHVGDVVSCHVELVKVGNTSMTIRVEVWAYSSIKMEKYQVTEGIFVFVAIDENGKPR
EEEECCCCEEEEEEEEEEECCCEEEEEEEEEEECCEEEEEEEECCCEEEEEEECCCCCCC
QVPKTQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]