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The map label for this gene is pilQ [H]

Identifier: 148360420

GI number: 148360420

Start: 1112155

End: 1114251

Strand: Direct

Name: pilQ [H]

Synonym: LPC_2359

Alternate gene names: 148360420

Gene position: 1112155-1114251 (Clockwise)

Preceding gene: 148360421

Following gene: 148360419

Centisome position: 31.1

GC content: 38.63

Gene sequence:

>2097_bases
GTGAGAAAAATTATCGCGGTTTTGATATTAATTAGTGCCAGTTTGAGTATGGCATATCCTAAAGATAATTCACTCATTTC
AGTAAAAGTATTACCATTGCCTGAAAACAGAGTGCGCATTGATTTTCAATTTTCCAAACCCTTAAAGCAGTTGCCCGCAA
GCTTTATTACTCAAAAGCCCCCACGTTTGGTGTTAGATTTTATCAGCACTGATATGCAAATTCCTTCAGATCAGAAAACT
AAAACCATTCAATTAGGCTCATTACATAGCTATAACATTGTTGCTGTTGGGGATAGAGTAAGAGCCATATTGGAGCTGGA
TCGTTCAGTGTCCTATTCTGGCAGTACGGCGGGTTCCGTTTATAGCCTTGTCCTGAATGGTAAAAGCAATGATTTATTTG
AAAATAGCAAGGAAGTATTCATAACGAACCAGGTTGTGAACGCCAAGCATGAAATTAAAAGAATTGATTTTCGTGGTATA
GAAAAGCAGGGCGGTAGAGTTTTAATTGATGTTTCTGATACTGGTATTCCAATTGATGTAACTCAAGTTGGGAAAGAAAT
AGTCGTTAATTTCCTGAATACCAGGATCCCTTTGAATTTAATGAAACGGTATGATGTTTCTGATTTTCACAGCCCTGTGC
AGATTATTACTATGCAACAGGAAGGAAAAAAGGTTCGTATGACCATTCTCAGCAAAGGGGATTATGGGCATTTTGTTTAT
CAGGTCAATAAACAATTTATGGTCGATGTCTTTCCTTTAACTGCGGAAGAAATTCGTCAGGCGAAATTGAAGAAACAGGT
ATTTACCGGTAAACGGATTTCTTTGAATTTCCAGAATATTAGTATTCGAGCTGTGCTTCAACTGCTGGCAGATTTTACCG
GAATCAATATGGTTGTCAGCGACAAAGTGCAAGGAGATATTACGCTAAGATTAAATGATATTCCCTGGGATCAGGCGCTG
GATATCATTTTAACCACACAAGGGTTAGATAAGCGCAGAAAGGGCAACGTCATGTTGATAGATACCAAGGCCTCCATGGA
TAAAATGGAGGAAGAACAACTCAAAAGTCAACAGACAATTGAAAAACTTGAGCCTATTCGTTCTGATTTAATACAGATTA
ATTATGCAAAGGCAGCAGATATTGCTGTTTTGATCAAGGATAAGCAAAATTCCCTATTATCAGACAGAGGAAAAATAAGT
GTTGATGCCAGAACGAATACAATCTGGATTCAGGATACTGGCACCAAAATTGAGGAAGTAAGGGAACTGATAAAGCAATT
GGATATCCCTGTTAAGCAAGTGCTTATTGAGGCAAGAATTGTTGAAGTAACTAAAGATTTTAGTCAAGATATTGGGATAC
GCTGGGGGGTATCAAGACCAACTCACTTAAGCGGTACATTGGAAGGTGCTAACGAGTTAGCGAGAGGAACAGCACCAGCT
AATGTTGTCCCCTTGGAAAGACGATTAAATCTTGATTTGGCAGCTGCTCCTTTAACTGGAGCTACACCGGCCTCGGTAGG
TATTGCTCTAGCCAAGCTTAATGATAACATTCTGCTTGATCTGGAATTGTCTGCTTTGGAAAGTGAAGGGCGTGCTGAAT
TAATATCCAGTCCCCGCCTGATTACTACGAATCAACAGGCAGCAGTCATCGAGTCTGGTGAGGAGATTCCCTATCAGGAG
GCAACATCGAGTGGAGCGACGGCTGTTGCATTTAAAAAAGCAGTGTTGAGTTTGAAAGTTACCCCGCAAATTACGCCTGA
CGGTAAAATTTTGATGGATTTACAGATAAATCAGGATACTCCTTCTCCACAAACATTCCTTGGTGTTCCAGCAATAATAA
CAAAGGAGATTCAGACGAATGTTCTGGTTAATAATGGACAAACCATAGTACTTGGGGGTATTTATAAGCAAGATAAGAAC
AAGGTAATCAATAGAATTCCTTTCTTTGGTGAGTTGCCTGTTGTCGGTATTTTATTTAGTAATAGACAAATCACATTGAA
AAATGAAGAATTACTTATTTTTATTACACCAAGAATAATAACGAATGCCCTATCTATAACAACGATAGAAGGACGTGAAA
AAGATGTTTATAAATAA

Upstream 100 bases:

>100_bases
AAATGATCTCATTAAATTGGAAGAAACTGTACAGAAATCAGGAACGTGGGAAAAACAGTCCACCACAATTAATTTGGATA
CTGGCAAGCAGGAGTAAGGC

Downstream 100 bases:

>100_bases
TCAAGATTGGATTAACTTTATCTCATTAATAAAGATAAAAAACATTAAGTTAATAGAAGTGCCTCAACACCGTGAACATG
TTATAATTAAAATATAACCC

Product: type IV pilus biogenesis protein PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MRKIIAVLILISASLSMAYPKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKPPRLVLDFISTDMQIPSDQKT
KTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSVYSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGI
EKQGGRVLIDVSDTGIPIDVTQVGKEIVVNFLNTRIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVSDKVQGDITLRLNDIPWDQAL
DIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTIEKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKIS
VDARTNTIWIQDTGTKIEEVRELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRLITTNQQAAVIESGEEIPYQE
ATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDTPSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKN
KVINRIPFFGELPVVGILFSNRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK

Sequences:

>Translated_698_residues
MRKIIAVLILISASLSMAYPKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKPPRLVLDFISTDMQIPSDQKT
KTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSVYSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGI
EKQGGRVLIDVSDTGIPIDVTQVGKEIVVNFLNTRIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVSDKVQGDITLRLNDIPWDQAL
DIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTIEKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKIS
VDARTNTIWIQDTGTKIEEVRELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRLITTNQQAAVIESGEEIPYQE
ATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDTPSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKN
KVINRIPFFGELPVVGILFSNRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK
>Mature_698_residues
MRKIIAVLILISASLSMAYPKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKPPRLVLDFISTDMQIPSDQKT
KTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSVYSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGI
EKQGGRVLIDVSDTGIPIDVTQVGKEIVVNFLNTRIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVSDKVQGDITLRLNDIPWDQAL
DIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTIEKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKIS
VDARTNTIWIQDTGTKIEEVRELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRLITTNQQAAVIESGEEIPYQE
ATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDTPSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKN
KVINRIPFFGELPVVGILFSNRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=420, Percent_Identity=33.3333333333333, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI87082242, Length=364, Percent_Identity=25.8241758241758, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 77499; Mature: 77499

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIAVLILISASLSMAYPKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKP
CHHHHHHHHHHHHHCEEECCCCCCEEEEEEEECCCCCEEEEEEECCHHHHCCHHHHCCCC
PRLVLDFISTDMQIPSDQKTKTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSV
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCEE
YSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGIEKQGGRVLIDVSDTGIPIDV
EEEEEECCCCCCCCCCCEEEEEEEHHCCHHHHEECCCCCCCCCCCEEEEEECCCCCEEEH
TQVGKEIVVNFLNTRIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
HHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEE
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVS
EECCEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCEEHHHHHHHHHCCCCCEEEEE
DKVQGDITLRLNDIPWDQALDIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTI
CCCCCEEEEEEECCCHHHCEEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
EKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKISVDARTNTIWIQDTGTKIEEV
HHHHHHHHHHEEEEECCCCCEEEEEECCCCCHHCCCCCEEEEECCCEEEEEECCCHHHHH
RELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHCCCCCC
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRL
CEEEHHHHCCCEEEECCCCCCCCHHHCEEEEEECCCEEEEEEEHHCCCCCCHHHHCCCEE
ITTNQQAAVIESGEEIPYQEATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDT
EECCCCEEEEECCCCCCCHHCCCCCCCHHEEEEEEEEEEECCEECCCCCEEEEEEECCCC
PSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKNKVINRIPFFGELPVVGILFS
CCCCEEECCCHHEECCCEEEEEEECCCEEEEEEEEECCHHHHHHHCCCCCCCCEEEEEEC
NRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK
CCEEEEECCEEEEEECHHHHHCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MRKIIAVLILISASLSMAYPKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKP
CHHHHHHHHHHHHHCEEECCCCCCEEEEEEEECCCCCEEEEEEECCHHHHCCHHHHCCCC
PRLVLDFISTDMQIPSDQKTKTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSV
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCEE
YSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGIEKQGGRVLIDVSDTGIPIDV
EEEEEECCCCCCCCCCCEEEEEEEHHCCHHHHEECCCCCCCCCCCEEEEEECCCCCEEEH
TQVGKEIVVNFLNTRIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
HHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEE
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVS
EECCEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCEEHHHHHHHHHCCCCCEEEEE
DKVQGDITLRLNDIPWDQALDIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTI
CCCCCEEEEEEECCCHHHCEEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
EKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKISVDARTNTIWIQDTGTKIEEV
HHHHHHHHHHEEEEECCCCCEEEEEECCCCCHHCCCCCEEEEECCCEEEEEECCCHHHHH
RELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHCCCCCC
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRL
CEEEHHHHCCCEEEECCCCCCCCHHHCEEEEEECCCEEEEEEEHHCCCCCCHHHHCCCEE
ITTNQQAAVIESGEEIPYQEATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDT
EECCCCEEEEECCCCCCCHHCCCCCCCHHEEEEEEEEEEECCEECCCCCEEEEEEECCCC
PSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKNKVINRIPFFGELPVVGILFS
CCCCEEECCCHHEECCCEEEEEEECCCEEEEEEEEECCHHHHHHHCCCCCCCCEEEEEEC
NRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK
CCEEEEECCEEEEEECHHHHHCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]