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The map label for this gene is ychK [H]

Identifier: 148360396

GI number: 148360396

Start: 1141890

End: 1142768

Strand: Direct

Name: ychK [H]

Synonym: LPC_2335

Alternate gene names: 148360396

Gene position: 1141890-1142768 (Clockwise)

Preceding gene: 148360397

Following gene: 148360395

Centisome position: 31.93

GC content: 41.41

Gene sequence:

>879_bases
TTGACAAATCAATACCCTAAAATCGGTTTGGCTTTAGGTAGTGGATCAGCGCGAGGCTGGGCTCATATTGGGGTAATTCA
ATCACTCAAACGATTGGGGGTAAGGATTGATTGTGTCGCTGGATGTTCCATAGGTGCATTGGTTGGCGCCATTTATGCTT
GTGGCACCCTGGATCTGTTTGAACAATGGGTGTTAAAGCTTAATAAAAGGGAAATGGCTAAACTCATTGATGTGAATTTT
TTAGGTGGCGGGGTTCTCTCTGGTAGTAAGTTGATGACCTTTTTCAAGGATTTTGGTCTTGAAAAAAATATTGAGGAGCT
CTCGCTACCTTTTAGTTCAGTTGCTACTGATTTGAGTACTGGACGTGAGATATGGCTAAGTAAAGGGTCTCTTGAGCTTG
CTATTCGTTCATCCATGTCTTTACCAGGGTTATTTACCCCGCAGCGTTATAAGGATTGCTGGTTAGTCGATGGTGGCTTG
GTTAATCCAGTTCCTATTACATTGTGTCGAGCTATGGGGGCAGATGTTGTAATCGCTGTCAATTTAAATCATGACTTGCT
AAGAGTACCTCCGAGCACGACAGAACACCCGGGGTTTTTTTCAGTTCTCTCAGGCCAATTTGATAAAATGATAAAAAGAA
TAATGGGAATCAGTGATGGGCCAGGATATTATGATGTTTTGACCAGAAGCATCAAAATAATGCAGGACCGGATAACCCGA
GCAAGAGCGGCAGGCGATCCTGCTGATTTGACTTTGGTTCCTCAATTAGGAAACATCATGCTTTATGATTTTCATAAAGC
AAAAGAGGCGATTCATGAAGGTGAAAATTGTGTTTTGCGAGAAAAAAATAATATTTTACAACTAGTTGGTCTAGAATAG

Upstream 100 bases:

>100_bases
GCGCTACATTTGGTTTTTGGATTTAGTGACATCCGGTGTTAAAAAACATGAAATTGATTGATTTAACGAGTGTGTACCCA
ACTATTTCCAGGAGTTATTC

Downstream 100 bases:

>100_bases
TAATTAAACAAGCTTAAGGAAGAGCCATGCAAAAAGAATCCAATTCCAATTCATTATTTGACTTACTGTTGAAAAATGAA
AAAAATTCGGCAGACCGTGT

Product: phosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTNQYPKIGLALGSGSARGWAHIGVIQSLKRLGVRIDCVAGCSIGALVGAIYACGTLDLFEQWVLKLNKREMAKLIDVNF
LGGGVLSGSKLMTFFKDFGLEKNIEELSLPFSSVATDLSTGREIWLSKGSLELAIRSSMSLPGLFTPQRYKDCWLVDGGL
VNPVPITLCRAMGADVVIAVNLNHDLLRVPPSTTEHPGFFSVLSGQFDKMIKRIMGISDGPGYYDVLTRSIKIMQDRITR
ARAAGDPADLTLVPQLGNIMLYDFHKAKEAIHEGENCVLREKNNILQLVGLE

Sequences:

>Translated_292_residues
MTNQYPKIGLALGSGSARGWAHIGVIQSLKRLGVRIDCVAGCSIGALVGAIYACGTLDLFEQWVLKLNKREMAKLIDVNF
LGGGVLSGSKLMTFFKDFGLEKNIEELSLPFSSVATDLSTGREIWLSKGSLELAIRSSMSLPGLFTPQRYKDCWLVDGGL
VNPVPITLCRAMGADVVIAVNLNHDLLRVPPSTTEHPGFFSVLSGQFDKMIKRIMGISDGPGYYDVLTRSIKIMQDRITR
ARAAGDPADLTLVPQLGNIMLYDFHKAKEAIHEGENCVLREKNNILQLVGLE
>Mature_291_residues
TNQYPKIGLALGSGSARGWAHIGVIQSLKRLGVRIDCVAGCSIGALVGAIYACGTLDLFEQWVLKLNKREMAKLIDVNFL
GGGVLSGSKLMTFFKDFGLEKNIEELSLPFSSVATDLSTGREIWLSKGSLELAIRSSMSLPGLFTPQRYKDCWLVDGGLV
NPVPITLCRAMGADVVIAVNLNHDLLRVPPSTTEHPGFFSVLSGQFDKMIKRIMGISDGPGYYDVLTRSIKIMQDRITRA
RAAGDPADLTLVPQLGNIMLYDFHKAKEAIHEGENCVLREKNNILQLVGLE

Specific function: Unknown

COG id: COG1752

COG function: function code R; Predicted esterase of the alpha-beta hydrolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 patatin domain [H]

Homologues:

Organism=Homo sapiens, GI260656037, Length=182, Percent_Identity=33.5164835164835, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI260656039, Length=182, Percent_Identity=33.5164835164835, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI260656043, Length=182, Percent_Identity=33.5164835164835, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI260656041, Length=182, Percent_Identity=33.5164835164835, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI116256487, Length=182, Percent_Identity=33.5164835164835, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI148727290, Length=186, Percent_Identity=34.4086021505376, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI148727335, Length=186, Percent_Identity=34.4086021505376, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI226510936, Length=295, Percent_Identity=43.0508474576271, Blast_Score=244, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71997299, Length=165, Percent_Identity=31.5151515151515, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71997289, Length=165, Percent_Identity=31.5151515151515, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193204778, Length=166, Percent_Identity=30.1204819277108, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323581, Length=189, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571388, Length=183, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281376913, Length=183, Percent_Identity=32.7868852459016, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016035
- InterPro:   IPR001423
- InterPro:   IPR002641 [H]

Pfam domain/function: PF01734 Patatin [H]

EC number: NA

Molecular weight: Translated: 31882; Mature: 31750

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQYPKIGLALGSGSARGWAHIGVIQSLKRLGVRIDCVAGCSIGALVGAIYACGTLDLF
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCHHHHH
EQWVLKLNKREMAKLIDVNFLGGGVLSGSKLMTFFKDFGLEKNIEELSLPFSSVATDLST
HHHHHHHCHHHHHHHHHEEECCCCCCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHC
GREIWLSKGSLELAIRSSMSLPGLFTPQRYKDCWLVDGGLVNPVPITLCRAMGADVVIAV
CCEEEEECCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEEE
NLNHDLLRVPPSTTEHPGFFSVLSGQFDKMIKRIMGISDGPGYYDVLTRSIKIMQDRITR
ECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ARAAGDPADLTLVPQLGNIMLYDFHKAKEAIHEGENCVLREKNNILQLVGLE
HHCCCCCCCEEECCCCCCEEEEEHHHHHHHHHCCCCEEEECCCCEEEEEECC
>Mature Secondary Structure 
TNQYPKIGLALGSGSARGWAHIGVIQSLKRLGVRIDCVAGCSIGALVGAIYACGTLDLF
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCHHHHH
EQWVLKLNKREMAKLIDVNFLGGGVLSGSKLMTFFKDFGLEKNIEELSLPFSSVATDLST
HHHHHHHCHHHHHHHHHEEECCCCCCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHC
GREIWLSKGSLELAIRSSMSLPGLFTPQRYKDCWLVDGGLVNPVPITLCRAMGADVVIAV
CCEEEEECCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEEE
NLNHDLLRVPPSTTEHPGFFSVLSGQFDKMIKRIMGISDGPGYYDVLTRSIKIMQDRITR
ECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ARAAGDPADLTLVPQLGNIMLYDFHKAKEAIHEGENCVLREKNNILQLVGLE
HHCCCCCCCEEECCCCCCEEEEEHHHHHHHHHCCCCEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8282700; 9097039; 8905232; 9278503 [H]