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The map label for this gene is tldD [H]

Identifier: 148360397

GI number: 148360397

Start: 1140327

End: 1141769

Strand: Direct

Name: tldD [H]

Synonym: LPC_2336

Alternate gene names: 148360397

Gene position: 1140327-1141769 (Clockwise)

Preceding gene: 148360398

Following gene: 148360396

Centisome position: 31.88

GC content: 43.8

Gene sequence:

>1443_bases
ATGACAAAATCTCTTGCGATAGCAAAAAATATTTTATTGACACCAGCTTCCCTGGATGAAGCCGGCATAGAAAAATTATT
CAAGACCATGTTTAATCGGAACGTCGATGATGCTGATCTTTATTTCCAAAGTTGTAGTTATGAATCCTGGTATTTGGAAG
ATTCAGAGGTTAAAAGCGGTAATTTTTCTCTGGATAAGGGGGTAGGGATTAGGGCTGTAAGCGGTGATAAAACCGGCTTT
GCTTATTGTGATGATATATTGCTGCCTTCCATGCTTCGTGCTGCCGATGCGGCGCGCTCCATAGCCCTTTCTGGTTCAAA
AACAGTACCGGCCGTCAAGGTATTAAAGGCTTCTGTAAATCGGTATGAGAGTTTAAATCCTTTGGAAGGAATGAGCAAAC
AGGAGAAAATCGCTTTATTGGAAGCCATTGATAAAGAGGCCCGTAGTCTTGATCCTCGAGTGATACAGGTTAATGCCACT
TTAACTGGTTGCTATGAAGTAGTAATGGTTGCCAATATGGATGGGCAGATGATGGCTGATGTGAGGCCATTGGTTAGCAT
TAATGTCAGTGTTATTGTTGAAGACAGTCATGGTAGAAGAGAATCGGCGAGATCAGGCGGTGGTGGACGAGTAGCTTATT
CCTATTTTACCGAGAAAGAAAACGCCTTGAGTTATGCGCGTGAAGCGGTACGGGAAGCATTAACCAATTTGAAGGCAGAA
CCAGCTCCTGCTGGAACCATGCCAGTTGTTTTGGGCCCAGGATGGCCAGGGGTACTTCTTCATGAAGCCGTTGGACATGG
TTTGGAGGGTGATTTTAATCGCAAGGGATTATCTGCTTTTTCAGGGAGACTGGGTCAGCAGGTTGCTGCTGCAGGCGTTA
CAGTTGTAGACGATGGCACTTTAGAGAATCGACGTGGCTCTCTGACTATAGACGACGAAGGGACGCCATCGCAATGCACG
ACTTTAATTGATAATGGAATTTTAGTGAATTACATGCAGGACAAGTTGAATGCCAAGCTTATGGGAATGCAATCAACAGG
TAATTGTCGTCGTGAATCCTATGCTCATGTCCCAATGCCGAGAATGACCAACACTTATATGCTGTCAGGACAGTACGACC
CTCAGGAAATTATTAGCACTGTAAAAAAAGGATTGTATGCGGTGAATTTTGGAGGCGGACAAGTTGATATTACTTCTGGC
CAGTTTGTATTTTCTGCGAGTGAGGCTTATTTAATAGAGAATGGCAAGATTACAAAACCAGTGAAAGGAGCCACTTTAAT
TGGCAATGGCCCTGATGTGATGAAAAAAATAAGTATGATTGGTAATGATTTGGCATTGGATAGAGGGATTGGTGTATGTG
GAAAAGAAGGACAATCTGTTCCCGTTGGCGTGGGACAACCCACTTTGAAAATTGATGCCTTGACGGTTGGCGGAACCAAG
TAA

Upstream 100 bases:

>100_bases
AGGGAGTAATTCTGGCTGATATTGATTTAGAGAGATTGTCACAGTTGAGAAGACAATTTCCGTGTGTTGAACATCATGTT
TTAATGTAAAAGGTATATAA

Downstream 100 bases:

>100_bases
GAAAATGTCAGTTTAGCATTGCGCTACATTTGGTTTTTGGATTTAGTGACATCCGGTGTTAAAAAACATGAAATTGATTG
ATTTAACGAGTGTGTACCCA

Product: TldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTKSLAIAKNILLTPASLDEAGIEKLFKTMFNRNVDDADLYFQSCSYESWYLEDSEVKSGNFSLDKGVGIRAVSGDKTGF
AYCDDILLPSMLRAADAARSIALSGSKTVPAVKVLKASVNRYESLNPLEGMSKQEKIALLEAIDKEARSLDPRVIQVNAT
LTGCYEVVMVANMDGQMMADVRPLVSINVSVIVEDSHGRRESARSGGGGRVAYSYFTEKENALSYAREAVREALTNLKAE
PAPAGTMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGLSAFSGRLGQQVAAAGVTVVDDGTLENRRGSLTIDDEGTPSQCT
TLIDNGILVNYMQDKLNAKLMGMQSTGNCRRESYAHVPMPRMTNTYMLSGQYDPQEIISTVKKGLYAVNFGGGQVDITSG
QFVFSASEAYLIENGKITKPVKGATLIGNGPDVMKKISMIGNDLALDRGIGVCGKEGQSVPVGVGQPTLKIDALTVGGTK

Sequences:

>Translated_480_residues
MTKSLAIAKNILLTPASLDEAGIEKLFKTMFNRNVDDADLYFQSCSYESWYLEDSEVKSGNFSLDKGVGIRAVSGDKTGF
AYCDDILLPSMLRAADAARSIALSGSKTVPAVKVLKASVNRYESLNPLEGMSKQEKIALLEAIDKEARSLDPRVIQVNAT
LTGCYEVVMVANMDGQMMADVRPLVSINVSVIVEDSHGRRESARSGGGGRVAYSYFTEKENALSYAREAVREALTNLKAE
PAPAGTMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGLSAFSGRLGQQVAAAGVTVVDDGTLENRRGSLTIDDEGTPSQCT
TLIDNGILVNYMQDKLNAKLMGMQSTGNCRRESYAHVPMPRMTNTYMLSGQYDPQEIISTVKKGLYAVNFGGGQVDITSG
QFVFSASEAYLIENGKITKPVKGATLIGNGPDVMKKISMIGNDLALDRGIGVCGKEGQSVPVGVGQPTLKIDALTVGGTK
>Mature_479_residues
TKSLAIAKNILLTPASLDEAGIEKLFKTMFNRNVDDADLYFQSCSYESWYLEDSEVKSGNFSLDKGVGIRAVSGDKTGFA
YCDDILLPSMLRAADAARSIALSGSKTVPAVKVLKASVNRYESLNPLEGMSKQEKIALLEAIDKEARSLDPRVIQVNATL
TGCYEVVMVANMDGQMMADVRPLVSINVSVIVEDSHGRRESARSGGGGRVAYSYFTEKENALSYAREAVREALTNLKAEP
APAGTMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGLSAFSGRLGQQVAAAGVTVVDDGTLENRRGSLTIDDEGTPSQCTT
LIDNGILVNYMQDKLNAKLMGMQSTGNCRRESYAHVPMPRMTNTYMLSGQYDPQEIISTVKKGLYAVNFGGGQVDITSGQ
FVFSASEAYLIENGKITKPVKGATLIGNGPDVMKKISMIGNDLALDRGIGVCGKEGQSVPVGVGQPTLKIDALTVGGTK

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=481, Percent_Identity=60.2910602910603, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1790682, Length=406, Percent_Identity=22.6600985221675, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51258; Mature: 51127

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSLAIAKNILLTPASLDEAGIEKLFKTMFNRNVDDADLYFQSCSYESWYLEDSEVKSG
CCCCHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCCCCCCC
NFSLDKGVGIRAVSGDKTGFAYCDDILLPSMLRAADAARSIALSGSKTVPAVKVLKASVN
CCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHH
RYESLNPLEGMSKQEKIALLEAIDKEARSLDPRVIQVNATLTGCYEVVMVANMDGQMMAD
HHCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECEEEEEEEECCCCCHHHC
VRPLVSINVSVIVEDSHGRRESARSGGGGRVAYSYFTEKENALSYAREAVREALTNLKAE
CCCEEEEEEEEEEECCCCCHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCC
PAPAGTMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGLSAFSGRLGQQVAAAGVTVVDDGT
CCCCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCC
LENRRGSLTIDDEGTPSQCTTLIDNGILVNYMQDKLNAKLMGMQSTGNCRRESYAHVPMP
CCCCCCCEEECCCCCHHHHHHHHCCCEEEEEHHHCCCEEEEEECCCCCCCCCCCCCCCCC
RMTNTYMLSGQYDPQEIISTVKKGLYAVNFGGGQVDITSGQFVFSASEAYLIENGKITKP
CCCCEEEEECCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEEECCEECCC
VKGATLIGNGPDVMKKISMIGNDLALDRGIGVCGKEGQSVPVGVGQPTLKIDALTVGGTK
CCCCEEECCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
TKSLAIAKNILLTPASLDEAGIEKLFKTMFNRNVDDADLYFQSCSYESWYLEDSEVKSG
CCCHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCCCCCCC
NFSLDKGVGIRAVSGDKTGFAYCDDILLPSMLRAADAARSIALSGSKTVPAVKVLKASVN
CCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHH
RYESLNPLEGMSKQEKIALLEAIDKEARSLDPRVIQVNATLTGCYEVVMVANMDGQMMAD
HHCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECEEEEEEEECCCCCHHHC
VRPLVSINVSVIVEDSHGRRESARSGGGGRVAYSYFTEKENALSYAREAVREALTNLKAE
CCCEEEEEEEEEEECCCCCHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCC
PAPAGTMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGLSAFSGRLGQQVAAAGVTVVDDGT
CCCCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCC
LENRRGSLTIDDEGTPSQCTTLIDNGILVNYMQDKLNAKLMGMQSTGNCRRESYAHVPMP
CCCCCCCEEECCCCCHHHHHHHHCCCEEEEEHHHCCCEEEEEECCCCCCCCCCCCCCCCC
RMTNTYMLSGQYDPQEIISTVKKGLYAVNFGGGQVDITSGQFVFSASEAYLIENGKITKP
CCCCEEEEECCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEEECCEECCC
VKGATLIGNGPDVMKKISMIGNDLALDRGIGVCGKEGQSVPVGVGQPTLKIDALTVGGTK
CCCCEEECCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]