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The map label for this gene is ybeC [H]

Identifier: 148360160

GI number: 148360160

Start: 2878026

End: 2879732

Strand: Reverse

Name: ybeC [H]

Synonym: LPC_2091

Alternate gene names: 148360160

Gene position: 2879732-2878026 (Counterclockwise)

Preceding gene: 148360158

Following gene: 148360161

Centisome position: 80.52

GC content: 41.07

Gene sequence:

>1707_bases
ATGATATTTCTGTTTACAATGCAAAAATATAATGATTTCGCTCTGCTGACTGGCGAATTGTTTGCCTGCATCAAAATCAT
AAGGACATGTGAAAATCAGATGAATAAAAATTTAAGTGCTTTGAGTTTACTTTGGATTTCAATTACCAGCATGGTAGGCT
CAGGCTGGTTATTTGGTTCTTTATATTCTGCTCATTTTGCTGGTCCTGCTGCCATTATCGCTTGGCCACTGGCAGGTTTT
TTACTTCTGTTTGTTGCCTTGTCTTACGCTGAGTTAGGTACGATGTTTCCACAGTCCGACAGCCTGGCTTGCTTGCCTTT
ATATACCCATGGACGTTTGACTGGCATTATCATGAATGTCATGACGTGGTTTTCCCTTGCCATTTTGCCAGTGATTGAAA
CGCAAGGTGTCATTCAATATGCCAGTAATTACATTCCAGATCTGGTATCTCATGACGCTTTGCACTATCGAAATACGCCA
GCAGGTTATATGCTGTCCCTGGTTGTATTAATGAGTTTTGTTTTGTTTAATTATTTTGGTATTGGTTTGTTTGCCCGCAT
TAATGCCGCATTTACTATCTGGAAGATAATAATCCCTATTCTTACTATCGCAAGCTTGGTAACCATGAGTTACCACCCGG
GTAATTTTTTTCAGCACGGTGGTTTTATGCCTTATGGTTGGCAGGGCGTTATGGCAGCAATGTCAAGCGGAGGTGTGCTT
TTTTCACTTTTAGGGTTTCGACAAGTGGTTATCATGATGGGTGAATTGGAGAAACCAGGACAATACATACCCCTGATTTT
GGGTGGTTCACTAGTGTTCGTGACGTTACTTTACACTGGTTTACAATGGTCCTTTGTTGGGAGTGTTAGCGAACAAGCGC
TGGAAAAAGGGTGGGTGAATTTGTCTTTTACTGGTGATGCAGGACCATTTGCCGCTCTCGCTGCACTGGCCGGTATGCTT
TGGTTGAGTATTTTATTGTACGCCGATGCTTTTATATCACCTTATTCCACTGGTCTTGTTTATTCAACCACAGCAGCTCA
CATGCTAAGCAGTATGGGCTCAGTTGTTCCTGCACCTGTAATTCTTACCAAACAAAACAGGTATCAAGTTCCCTGGGTTA
GTTTAGGCGTAAATTTCTTACTCGCCGCCACCATGTCGCTCGTGTTGCACGGATGGCAAGAAATGTCGGCTTTTCTTGTG
GCAATATTAATGATTAGCTATTCCATAGGGCCTGTAGCACTGGTTTGCTTACGTCAGCAATTACCTCACTATAAGCGTCC
TTTTCGTTTACAAGGGAGTAACCTTATTGGTTTTCTCGGATTTTATGTTTGTACAGTTGGGGTTTATTGGGCAGGTTTCC
ATAGCGTACGAAAGTTATTGGTGATCACTATTCTGGGAGTAGTGTGTTCTTTCTTCTATTGCCTTATAAAAAATACACAT
CGGGAGATTGATAGCAAACAAGCACTATGGTTTATATTTTATCTTTTTGGACTTGGTATTTTCTCATTTCTTGGTAATTA
TGGTGGTAAGCATATCCTTCCCCAGTATTGGGATTTGTTGTATTTATTAGTTTTCAGCTTGCTTGTATTTGGTTTTGCCC
TATTGTCCAGAAAGCCCAGTGCCTACACTCAAAACATGGTTGCCCAAAATACAAACACTAAGATAACTGCTCCTGCTTTC
TCAATTGAGCGATATGATATTGCTTGA

Upstream 100 bases:

>100_bases
AGAAAATCACTGCTGCGAGTTCTTGTTTTTCATTTTTCCTGATGCTGGAGGGTATTCGTAACCTACCTGGTTAAACTTGA
CTCTTATAGGGTTGGTAGTC

Downstream 100 bases:

>100_bases
TTAGAGTCCTTAATGATCAATATTATTCAATGTTGATCTTGACAAGATCATTATGGATCACAATAATGCGATTGGTTTTT
TAAAGTCACTTTGCTGCAAG

Product: amino acid permease

Products: Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MIFLFTMQKYNDFALLTGELFACIKIIRTCENQMNKNLSALSLLWISITSMVGSGWLFGSLYSAHFAGPAAIIAWPLAGF
LLLFVALSYAELGTMFPQSDSLACLPLYTHGRLTGIIMNVMTWFSLAILPVIETQGVIQYASNYIPDLVSHDALHYRNTP
AGYMLSLVVLMSFVLFNYFGIGLFARINAAFTIWKIIIPILTIASLVTMSYHPGNFFQHGGFMPYGWQGVMAAMSSGGVL
FSLLGFRQVVIMMGELEKPGQYIPLILGGSLVFVTLLYTGLQWSFVGSVSEQALEKGWVNLSFTGDAGPFAALAALAGML
WLSILLYADAFISPYSTGLVYSTTAAHMLSSMGSVVPAPVILTKQNRYQVPWVSLGVNFLLAATMSLVLHGWQEMSAFLV
AILMISYSIGPVALVCLRQQLPHYKRPFRLQGSNLIGFLGFYVCTVGVYWAGFHSVRKLLVITILGVVCSFFYCLIKNTH
REIDSKQALWFIFYLFGLGIFSFLGNYGGKHILPQYWDLLYLLVFSLLVFGFALLSRKPSAYTQNMVAQNTNTKITAPAF
SIERYDIA

Sequences:

>Translated_568_residues
MIFLFTMQKYNDFALLTGELFACIKIIRTCENQMNKNLSALSLLWISITSMVGSGWLFGSLYSAHFAGPAAIIAWPLAGF
LLLFVALSYAELGTMFPQSDSLACLPLYTHGRLTGIIMNVMTWFSLAILPVIETQGVIQYASNYIPDLVSHDALHYRNTP
AGYMLSLVVLMSFVLFNYFGIGLFARINAAFTIWKIIIPILTIASLVTMSYHPGNFFQHGGFMPYGWQGVMAAMSSGGVL
FSLLGFRQVVIMMGELEKPGQYIPLILGGSLVFVTLLYTGLQWSFVGSVSEQALEKGWVNLSFTGDAGPFAALAALAGML
WLSILLYADAFISPYSTGLVYSTTAAHMLSSMGSVVPAPVILTKQNRYQVPWVSLGVNFLLAATMSLVLHGWQEMSAFLV
AILMISYSIGPVALVCLRQQLPHYKRPFRLQGSNLIGFLGFYVCTVGVYWAGFHSVRKLLVITILGVVCSFFYCLIKNTH
REIDSKQALWFIFYLFGLGIFSFLGNYGGKHILPQYWDLLYLLVFSLLVFGFALLSRKPSAYTQNMVAQNTNTKITAPAF
SIERYDIA
>Mature_568_residues
MIFLFTMQKYNDFALLTGELFACIKIIRTCENQMNKNLSALSLLWISITSMVGSGWLFGSLYSAHFAGPAAIIAWPLAGF
LLLFVALSYAELGTMFPQSDSLACLPLYTHGRLTGIIMNVMTWFSLAILPVIETQGVIQYASNYIPDLVSHDALHYRNTP
AGYMLSLVVLMSFVLFNYFGIGLFARINAAFTIWKIIIPILTIASLVTMSYHPGNFFQHGGFMPYGWQGVMAAMSSGGVL
FSLLGFRQVVIMMGELEKPGQYIPLILGGSLVFVTLLYTGLQWSFVGSVSEQALEKGWVNLSFTGDAGPFAALAALAGML
WLSILLYADAFISPYSTGLVYSTTAAHMLSSMGSVVPAPVILTKQNRYQVPWVSLGVNFLLAATMSLVLHGWQEMSAFLV
AILMISYSIGPVALVCLRQQLPHYKRPFRLQGSNLIGFLGFYVCTVGVYWAGFHSVRKLLVITILGVVCSFFYCLIKNTH
REIDSKQALWFIFYLFGLGIFSFLGNYGGKHILPQYWDLLYLLVFSLLVFGFALLSRKPSAYTQNMVAQNTNTKITAPAF
SIERYDIA

Specific function: Uptake of an yet unknown amino-acid with the concomitant import of a proton [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17533459, Length=272, Percent_Identity=27.5735294117647, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 62916; Mature: 62916

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLFTMQKYNDFALLTGELFACIKIIRTCENQMNKNLSALSLLWISITSMVGSGWLFGS
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
LYSAHFAGPAAIIAWPLAGFLLLFVALSYAELGTMFPQSDSLACLPLYTHGRLTGIIMNV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHH
MTWFSLAILPVIETQGVIQYASNYIPDLVSHDALHYRNTPAGYMLSLVVLMSFVLFNYFG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHH
IGLFARINAAFTIWKIIIPILTIASLVTMSYHPGNFFQHGGFMPYGWQGVMAAMSSGGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHCCCHH
FSLLGFRQVVIMMGELEKPGQYIPLILGGSLVFVTLLYTGLQWSFVGSVSEQALEKGWVN
HHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEE
LSFTGDAGPFAALAALAGMLWLSILLYADAFISPYSTGLVYSTTAAHMLSSMGSVVPAPV
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCCCCCE
ILTKQNRYQVPWVSLGVNFLLAATMSLVLHGWQEMSAFLVAILMISYSIGPVALVCLRQQ
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LPHYKRPFRLQGSNLIGFLGFYVCTVGVYWAGFHSVRKLLVITILGVVCSFFYCLIKNTH
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REIDSKQALWFIFYLFGLGIFSFLGNYGGKHILPQYWDLLYLLVFSLLVFGFALLSRKPS
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
AYTQNMVAQNTNTKITAPAFSIERYDIA
HHHHHHHHCCCCCEEECCCEECCCCCCC
>Mature Secondary Structure
MIFLFTMQKYNDFALLTGELFACIKIIRTCENQMNKNLSALSLLWISITSMVGSGWLFGS
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
LYSAHFAGPAAIIAWPLAGFLLLFVALSYAELGTMFPQSDSLACLPLYTHGRLTGIIMNV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHH
MTWFSLAILPVIETQGVIQYASNYIPDLVSHDALHYRNTPAGYMLSLVVLMSFVLFNYFG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHH
IGLFARINAAFTIWKIIIPILTIASLVTMSYHPGNFFQHGGFMPYGWQGVMAAMSSGGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHCCCHH
FSLLGFRQVVIMMGELEKPGQYIPLILGGSLVFVTLLYTGLQWSFVGSVSEQALEKGWVN
HHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEE
LSFTGDAGPFAALAALAGMLWLSILLYADAFISPYSTGLVYSTTAAHMLSSMGSVVPAPV
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCCCCCE
ILTKQNRYQVPWVSLGVNFLLAATMSLVLHGWQEMSAFLVAILMISYSIGPVALVCLRQQ
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LPHYKRPFRLQGSNLIGFLGFYVCTVGVYWAGFHSVRKLLVITILGVVCSFFYCLIKNTH
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REIDSKQALWFIFYLFGLGIFSFLGNYGGKHILPQYWDLLYLLVFSLLVFGFALLSRKPS
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
AYTQNMVAQNTNTKITAPAFSIERYDIA
HHHHHHHHCCCCCEEECCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]