Click here to switch to the map view.

The map label for this gene is pheA [H]

Identifier: 148360008

GI number: 148360008

Start: 3036424

End: 3037008

Strand: Direct

Name: pheA [H]

Synonym: LPC_1939

Alternate gene names: 148360008

Gene position: 3036424-3037008 (Clockwise)

Preceding gene: 148360009

Following gene: 148360007

Centisome position: 84.9

GC content: 38.8

Gene sequence:

>585_bases
ATGAATAATCTCGTTGAAAAAAAAGAAGCCTTTCGCTTTGGTGTTTCAGGGGATATTGGATCATTTTCTGAGGAAGCGGC
TTTGCTTTATGCCAGGAAAAAAGGCTTTAATGCCCATCTCGTTCATTTGCTGGATATGGAAGGCGTTTTAAATGCCATTG
AGAATGAAACGATAGAGCTGGGCATATTACCCGTTGTTAACCTTTTAGGAGGATTGGTAAAGCCAGCATTTCAGGCTATG
GGCAAATATTCATTTACTCCCATCGATGAGATTTGGCATGACATAAACCAATGCCTGTTAGTTAAGACAAATACTCAAAA
TCATAAAATCACACATATTGTGTCCCATCCTCAAGGCTTTGCCCAATGCAAAAAATTCCTAAAAAACAAATTTAAGAATG
CGAAAAAAATAGAATGGATCGATACAGCAAAAGCAGCAAAGGATTTGGCGGAAGGAATATTGCCACCCCATGCCGCAGTT
ATTGCGTCGGCACGTTGTGCACCACTTTATGATTTGAAAATCAGTGCGAGAAATATTCAGGACAGCCATCTGAACAGAAC
GGCTTTTATATTAGTTAAAAAATAA

Upstream 100 bases:

>100_bases
CCGATAACATTGATTTAAGCGGGTTATCCGTTACCGATCCATGCCTCAGTTGGGAGAAGACAGAATCGTTCCTGTTGGAG
CTGGCGGAGAGGGAAGCATT

Downstream 100 bases:

>100_bases
AGTGACAAGGTCCCTATCCGCTAAGGAGTTCATCATGAGTACGATTGAAGAACTAAGAAAACAAATTGAGCAAACTGATG
CAGACATCATTGAAAAGTTG

Product: chorismate mutase/prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MNNLVEKKEAFRFGVSGDIGSFSEEAALLYARKKGFNAHLVHLLDMEGVLNAIENETIELGILPVVNLLGGLVKPAFQAM
GKYSFTPIDEIWHDINQCLLVKTNTQNHKITHIVSHPQGFAQCKKFLKNKFKNAKKIEWIDTAKAAKDLAEGILPPHAAV
IASARCAPLYDLKISARNIQDSHLNRTAFILVKK

Sequences:

>Translated_194_residues
MNNLVEKKEAFRFGVSGDIGSFSEEAALLYARKKGFNAHLVHLLDMEGVLNAIENETIELGILPVVNLLGGLVKPAFQAM
GKYSFTPIDEIWHDINQCLLVKTNTQNHKITHIVSHPQGFAQCKKFLKNKFKNAKKIEWIDTAKAAKDLAEGILPPHAAV
IASARCAPLYDLKISARNIQDSHLNRTAFILVKK
>Mature_194_residues
MNNLVEKKEAFRFGVSGDIGSFSEEAALLYARKKGFNAHLVHLLDMEGVLNAIENETIELGILPVVNLLGGLVKPAFQAM
GKYSFTPIDEIWHDINQCLLVKTNTQNHKITHIVSHPQGFAQCKKFLKNKFKNAKKIEWIDTAKAAKDLAEGILPPHAAV
IASARCAPLYDLKISARNIQDSHLNRTAFILVKK

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=188, Percent_Identity=27.1276595744681, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 21571; Mature: 21571

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLVEKKEAFRFGVSGDIGSFSEEAALLYARKKGFNAHLVHLLDMEGVLNAIENETIEL
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCEEE
GILPVVNLLGGLVKPAFQAMGKYSFTPIDEIWHDINQCLLVKTNTQNHKITHIVSHPQGF
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEEECCCCCEEEEEECCCCHH
AQCKKFLKNKFKNAKKIEWIDTAKAAKDLAEGILPPHAAVIASARCAPLYDLKISARNIQ
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECCCCC
DSHLNRTAFILVKK
HHHCCCEEEEEEEC
>Mature Secondary Structure
MNNLVEKKEAFRFGVSGDIGSFSEEAALLYARKKGFNAHLVHLLDMEGVLNAIENETIEL
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCEEE
GILPVVNLLGGLVKPAFQAMGKYSFTPIDEIWHDINQCLLVKTNTQNHKITHIVSHPQGF
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEEECCCCCEEEEEECCCCHH
AQCKKFLKNKFKNAKKIEWIDTAKAAKDLAEGILPPHAAVIASARCAPLYDLKISARNIQ
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECCCCC
DSHLNRTAFILVKK
HHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512561; 1444388 [H]