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The map label for this gene is aroF [H]

Identifier: 148360009

GI number: 148360009

Start: 3035384

End: 3036427

Strand: Direct

Name: aroF [H]

Synonym: LPC_1940

Alternate gene names: 148360009

Gene position: 3035384-3036427 (Clockwise)

Preceding gene: 148360012

Following gene: 148360008

Centisome position: 84.87

GC content: 42.72

Gene sequence:

>1044_bases
ATGAGTTATTCCATCTTAAAAAAACTGCCACCAATAGAAAAAATCATCCGGGAATTGCCACTATCCCACTCCGCCTATCT
ACAAATTGCTCAAGACCGGCAAGAGATCAAAGCTATTTTGGAAGGGCGAGATAAACGTCTTTTGATGATAGTTGGTCCTT
GTTCAGCATGGCCTAAAAAAGCGGTATTGGAATACGCTGAGCGTTTGGTACAACTCAACAGCAAAGTAAAACACGCTTTA
AAATTAATCATGCGCGTTTACATTCAAAAGCCAAGAACCACCAAAGGCTGGACTGGACCGGTGAATCAACCCGATTTATT
TTCAACTCCTGATATTGAGACAGGTATAAAATATACCCGGGACATGATGATAAAAGTCATTCAAATGGGGCTCCCTATCG
CTGATGAGGCTCTTTTCACCCATAATGCCAAAGGATTTCTTGAACTTCTGTCCTGGGTTGCAATAGGAGCCCGTAGTTCA
GAGGATCAAGAGCATCGAATTTTTGCCTCCGCCCTTGACTGTGCTGTAGGATTAAAAAACCCTACACATGGTTCACTCGC
TGTCGGAGTTAACAGCCTGGTTGCATCACAGCATCCTCATGTCGCTGTCTTCGATGGCTATGAAGTGCAAACCCATGGTA
ATCATCATGCTCATCTCGTTCTGCGTGGTTCAAACCAAGCTCCCAATTACTCCGTTTCTCATCTGGAGGAAGTCATGTAC
TACATGGGCATGCATCAAATAGTGAACCCTTCTGTCATTATTGATGTTAGCCATGACAACTGTCTGGTGAATGGAAAAAA
AAATCATCAGCTACAACCAGAGATTGCATTTAATATTCTGGAAAGCATCAAAAACAGACCTGATTTAAAACAACTGGTCA
AGGGGTTCATGGTAGAAAGTTTCATCAAGGAAGGTAATCAAAAATTAGATTCTATCAATCCCGATAACATTGATTTAAGC
GGGTTATCCGTTACCGATCCATGCCTCAGTTGGGAGAAGACAGAATCGTTCCTGTTGGAGCTGGCGGAGAGGGAAGCATT
ATGA

Upstream 100 bases:

>100_bases
CTAATAAGGGGGTTGGGTACAAAAGAGGAGTGTGAACGATGAACCACCAATGTCAAATTCATCATCCATCTAAAGCGCTT
TCTGGCTTGAGGAGGATACG

Downstream 100 bases:

>100_bases
ATAATCTCGTTGAAAAAAAAGAAGCCTTTCGCTTTGGTGTTTCAGGGGATATTGGATCATTTTCTGAGGAAGCGGCTTTG
CTTTATGCCAGGAAAAAAGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSYSILKKLPPIEKIIRELPLSHSAYLQIAQDRQEIKAILEGRDKRLLMIVGPCSAWPKKAVLEYAERLVQLNSKVKHAL
KLIMRVYIQKPRTTKGWTGPVNQPDLFSTPDIETGIKYTRDMMIKVIQMGLPIADEALFTHNAKGFLELLSWVAIGARSS
EDQEHRIFASALDCAVGLKNPTHGSLAVGVNSLVASQHPHVAVFDGYEVQTHGNHHAHLVLRGSNQAPNYSVSHLEEVMY
YMGMHQIVNPSVIIDVSHDNCLVNGKKNHQLQPEIAFNILESIKNRPDLKQLVKGFMVESFIKEGNQKLDSINPDNIDLS
GLSVTDPCLSWEKTESFLLELAEREAL

Sequences:

>Translated_347_residues
MSYSILKKLPPIEKIIRELPLSHSAYLQIAQDRQEIKAILEGRDKRLLMIVGPCSAWPKKAVLEYAERLVQLNSKVKHAL
KLIMRVYIQKPRTTKGWTGPVNQPDLFSTPDIETGIKYTRDMMIKVIQMGLPIADEALFTHNAKGFLELLSWVAIGARSS
EDQEHRIFASALDCAVGLKNPTHGSLAVGVNSLVASQHPHVAVFDGYEVQTHGNHHAHLVLRGSNQAPNYSVSHLEEVMY
YMGMHQIVNPSVIIDVSHDNCLVNGKKNHQLQPEIAFNILESIKNRPDLKQLVKGFMVESFIKEGNQKLDSINPDNIDLS
GLSVTDPCLSWEKTESFLLELAEREAL
>Mature_346_residues
SYSILKKLPPIEKIIRELPLSHSAYLQIAQDRQEIKAILEGRDKRLLMIVGPCSAWPKKAVLEYAERLVQLNSKVKHALK
LIMRVYIQKPRTTKGWTGPVNQPDLFSTPDIETGIKYTRDMMIKVIQMGLPIADEALFTHNAKGFLELLSWVAIGARSSE
DQEHRIFASALDCAVGLKNPTHGSLAVGVNSLVASQHPHVAVFDGYEVQTHGNHHAHLVLRGSNQAPNYSVSHLEEVMYY
MGMHQIVNPSVIIDVSHDNCLVNGKKNHQLQPEIAFNILESIKNRPDLKQLVKGFMVESFIKEGNQKLDSINPDNIDLSG
LSVTDPCLSWEKTESFLLELAEREAL

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=337, Percent_Identity=40.9495548961424, Blast_Score=244, Evalue=4e-66,
Organism=Escherichia coli, GI1786969, Length=340, Percent_Identity=37.3529411764706, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1787996, Length=341, Percent_Identity=35.7771260997067, Blast_Score=218, Evalue=6e-58,
Organism=Saccharomyces cerevisiae, GI6319726, Length=334, Percent_Identity=35.6287425149701, Blast_Score=203, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320240, Length=348, Percent_Identity=34.7701149425287, Blast_Score=199, Evalue=7e-52,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38922; Mature: 38791

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSILKKLPPIEKIIRELPLSHSAYLQIAQDRQEIKAILEGRDKRLLMIVGPCSAWPKK
CCCHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
AVLEYAERLVQLNSKVKHALKLIMRVYIQKPRTTKGWTGPVNQPDLFSTPDIETGIKYTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DMMIKVIQMGLPIADEALFTHNAKGFLELLSWVAIGARSSEDQEHRIFASALDCAVGLKN
HHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
PTHGSLAVGVNSLVASQHPHVAVFDGYEVQTHGNHHAHLVLRGSNQAPNYSVSHLEEVMY
CCCCCHHHHHHHHHHCCCCCEEEECCEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHH
YMGMHQIVNPSVIIDVSHDNCLVNGKKNHQLQPEIAFNILESIKNRPDLKQLVKGFMVES
HHHHHHHCCCEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FIKEGNQKLDSINPDNIDLSGLSVTDPCLSWEKTESFLLELAEREAL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYSILKKLPPIEKIIRELPLSHSAYLQIAQDRQEIKAILEGRDKRLLMIVGPCSAWPKK
CCHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
AVLEYAERLVQLNSKVKHALKLIMRVYIQKPRTTKGWTGPVNQPDLFSTPDIETGIKYTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DMMIKVIQMGLPIADEALFTHNAKGFLELLSWVAIGARSSEDQEHRIFASALDCAVGLKN
HHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
PTHGSLAVGVNSLVASQHPHVAVFDGYEVQTHGNHHAHLVLRGSNQAPNYSVSHLEEVMY
CCCCCHHHHHHHHHHCCCCCEEEECCEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHH
YMGMHQIVNPSVIIDVSHDNCLVNGKKNHQLQPEIAFNILESIKNRPDLKQLVKGFMVES
HHHHHHHCCCEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FIKEGNQKLDSINPDNIDLSGLSVTDPCLSWEKTESFLLELAEREAL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]