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The map label for this gene is hemA [H]

Identifier: 148359875

GI number: 148359875

Start: 2751576

End: 2752901

Strand: Direct

Name: hemA [H]

Synonym: LPC_1803

Alternate gene names: 148359875

Gene position: 2751576-2752901 (Clockwise)

Preceding gene: 148359874

Following gene: 148359876

Centisome position: 76.94

GC content: 40.27

Gene sequence:

>1326_bases
ATGAATCGTTTACAATTCGTTAATTCCCTTAAACAAATAAATCAAGATTCTATGGTATTTGTAGCTTGCGGGCTTAATCA
TAAAACTGCTCCAATTCATGTGCGTGAAAAAGTCGCACTGCAGCCAGCCATGCAAGATTCTCTATTGAGCAGTCTGCTTG
ATTTACCTGAAGTCAATGAAGCGGCTATTTTATCTACATGCAACCGGACTGAAATCTACTGTGATACCAATACCCCTGAG
GTTCTTGGAAACTGGTTAGCTCATGAACACCAATTATCAGAGGAATTATTATCTCAATTTTTGTATATCCATCAGGGAAA
AGAAGGAATCAAACATACCTTGCGTGTTGCCAGCGGTTTGGATTCCATGATGATAGGCGAACCACAAATCCTTGGCCAAA
TGAAACAGGCGTATCAACATGCTTGTCGTCTTGGCACAGTAAAAACACAATTACGGCCTGTGTTTGAATATATTTTCAGA
GCGTCCAAACGCATCAGAACTCGTAGCGGAATTGGAGCTAACCCCGTATCGATTGCCTATGCTGCTGTACAACTGATAGG
GCAATTATTTAAAAACTATCATTCCTTAAGTGTCTTTTTAATTGGTTCTGGAGAAACGGCCTCTCTGGTTGCTAAATACC
TGCATCAACATGGTGTCCATCGTTTTTTGATAGCGAGCCGCACTCTGGAAAATGCTCAAAAATTAGCTGAAACTTTCGGT
GGAAAAACACTGTCCATTGGTGATATCCCGCAATATTTACCTCTGGCTGATGTTGTTATTTCTGCCACAGCATGCCCACT
CCCATTCATCAATAAAAGCCTGGTTGAGCATGCCTTGGAACAAAGAAACCATGCCCCTATGTTTTTATTGGATTTGGCCG
TTCCTCGTGATATTGAAGGAAATGTCAATGAATTGGAACAAGTTCATCTCTATAATGTAGATGATTTACAATCCATGATA
GAAAAAGGGATGAATGAAAGGCGAAATGCGGCATTACAAGCAGAACAATTGATCGAAAGCGAACTGGATAACTACATTAG
ATGGCATCGCTCGCTTAGAGCTAAAGACGTCATTTGCGATTACCGCAATCAAATGCACACTTTGGCTCAACAGGAATTAC
AACGTGCTTTGAAAAAAATATCCGCTGGTCAAAATCAGCAAGACGTTTTAAATGAATTCAGTATGCGCTTGGTCAACAAG
CTAACTCATAACCCCACCATAGGTTTAAGACAAATAGCATGGGATAACAGAGAAGACTTACTTGACCTCGCACGATATCT
CTTTGATACAACAGCCAATCAATCATTATATGAAGAAATCTCTTGA

Upstream 100 bases:

>100_bases
CAATCTTGAGGAGGAAGAAGACGGGTAAAAAATATACTGTAAAATGATTGCAAGAAACAGAAATACAAGGAACCTTTCCT
TTTTCTCTACAAATTTTACA

Downstream 100 bases:

>100_bases
GTTAAAATTACAGCAAATGTTGGAGCGATACGAGGAAGTAGGCCGCTTATTGTCCGAAGCATCCATTATTGCCGATCAAA
ATCAATTTAAGTCTTTATCA

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MNRLQFVNSLKQINQDSMVFVACGLNHKTAPIHVREKVALQPAMQDSLLSSLLDLPEVNEAAILSTCNRTEIYCDTNTPE
VLGNWLAHEHQLSEELLSQFLYIHQGKEGIKHTLRVASGLDSMMIGEPQILGQMKQAYQHACRLGTVKTQLRPVFEYIFR
ASKRIRTRSGIGANPVSIAYAAVQLIGQLFKNYHSLSVFLIGSGETASLVAKYLHQHGVHRFLIASRTLENAQKLAETFG
GKTLSIGDIPQYLPLADVVISATACPLPFINKSLVEHALEQRNHAPMFLLDLAVPRDIEGNVNELEQVHLYNVDDLQSMI
EKGMNERRNAALQAEQLIESELDNYIRWHRSLRAKDVICDYRNQMHTLAQQELQRALKKISAGQNQQDVLNEFSMRLVNK
LTHNPTIGLRQIAWDNREDLLDLARYLFDTTANQSLYEEIS

Sequences:

>Translated_441_residues
MNRLQFVNSLKQINQDSMVFVACGLNHKTAPIHVREKVALQPAMQDSLLSSLLDLPEVNEAAILSTCNRTEIYCDTNTPE
VLGNWLAHEHQLSEELLSQFLYIHQGKEGIKHTLRVASGLDSMMIGEPQILGQMKQAYQHACRLGTVKTQLRPVFEYIFR
ASKRIRTRSGIGANPVSIAYAAVQLIGQLFKNYHSLSVFLIGSGETASLVAKYLHQHGVHRFLIASRTLENAQKLAETFG
GKTLSIGDIPQYLPLADVVISATACPLPFINKSLVEHALEQRNHAPMFLLDLAVPRDIEGNVNELEQVHLYNVDDLQSMI
EKGMNERRNAALQAEQLIESELDNYIRWHRSLRAKDVICDYRNQMHTLAQQELQRALKKISAGQNQQDVLNEFSMRLVNK
LTHNPTIGLRQIAWDNREDLLDLARYLFDTTANQSLYEEIS
>Mature_441_residues
MNRLQFVNSLKQINQDSMVFVACGLNHKTAPIHVREKVALQPAMQDSLLSSLLDLPEVNEAAILSTCNRTEIYCDTNTPE
VLGNWLAHEHQLSEELLSQFLYIHQGKEGIKHTLRVASGLDSMMIGEPQILGQMKQAYQHACRLGTVKTQLRPVFEYIFR
ASKRIRTRSGIGANPVSIAYAAVQLIGQLFKNYHSLSVFLIGSGETASLVAKYLHQHGVHRFLIASRTLENAQKLAETFG
GKTLSIGDIPQYLPLADVVISATACPLPFINKSLVEHALEQRNHAPMFLLDLAVPRDIEGNVNELEQVHLYNVDDLQSMI
EKGMNERRNAALQAEQLIESELDNYIRWHRSLRAKDVICDYRNQMHTLAQQELQRALKKISAGQNQQDVLNEFSMRLVNK
LTHNPTIGLRQIAWDNREDLLDLARYLFDTTANQSLYEEIS

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=412, Percent_Identity=41.504854368932, Blast_Score=332, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 49901; Mature: 49901

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLQFVNSLKQINQDSMVFVACGLNHKTAPIHVREKVALQPAMQDSLLSSLLDLPEVNE
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
AAILSTCNRTEIYCDTNTPEVLGNWLAHEHQLSEELLSQFLYIHQGKEGIKHTLRVASGL
HHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
DSMMIGEPQILGQMKQAYQHACRLGTVKTQLRPVFEYIFRASKRIRTRSGIGANPVSIAY
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AAVQLIGQLFKNYHSLSVFLIGSGETASLVAKYLHQHGVHRFLIASRTLENAQKLAETFG
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
GKTLSIGDIPQYLPLADVVISATACPLPFINKSLVEHALEQRNHAPMFLLDLAVPRDIEG
CCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
NVNELEQVHLYNVDDLQSMIEKGMNERRNAALQAEQLIESELDNYIRWHRSLRAKDVICD
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRNQMHTLAQQELQRALKKISAGQNQQDVLNEFSMRLVNKLTHNPTIGLRQIAWDNREDL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHH
LDLARYLFDTTANQSLYEEIS
HHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MNRLQFVNSLKQINQDSMVFVACGLNHKTAPIHVREKVALQPAMQDSLLSSLLDLPEVNE
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
AAILSTCNRTEIYCDTNTPEVLGNWLAHEHQLSEELLSQFLYIHQGKEGIKHTLRVASGL
HHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
DSMMIGEPQILGQMKQAYQHACRLGTVKTQLRPVFEYIFRASKRIRTRSGIGANPVSIAY
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AAVQLIGQLFKNYHSLSVFLIGSGETASLVAKYLHQHGVHRFLIASRTLENAQKLAETFG
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
GKTLSIGDIPQYLPLADVVISATACPLPFINKSLVEHALEQRNHAPMFLLDLAVPRDIEG
CCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
NVNELEQVHLYNVDDLQSMIEKGMNERRNAALQAEQLIESELDNYIRWHRSLRAKDVICD
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRNQMHTLAQQELQRALKKISAGQNQQDVLNEFSMRLVNKLTHNPTIGLRQIAWDNREDL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHH
LDLARYLFDTTANQSLYEEIS
HHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA