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The map label for this gene is rtn [H]

Identifier: 148358999

GI number: 148358999

Start: 1685324

End: 1686922

Strand: Reverse

Name: rtn [H]

Synonym: LPC_0884

Alternate gene names: 148358999

Gene position: 1686922-1685324 (Counterclockwise)

Preceding gene: 148359000

Following gene: 148358998

Centisome position: 47.17

GC content: 31.52

Gene sequence:

>1599_bases
ATGAGTAAGGTTATTCACAAATTATCTTTATTTCTTTTTAAAAAATTTAAAATCATATGGATTCTCTTAACTATTGGTAT
CCTGATTTCAGCTTTTTACGCTAATTGGAATATTAACCAAAAAAGAGCTTATAAAGATTTAAAAGAAGTTGCAATCAATC
TCAGTAACAACATAGATGGTTTTATCGAAGATCTACTTCAGGAAATCTATGCTTTGCCTGTATATGGGAAAAAAATTGTC
GATTGTAAATCAGATTTATATCCATTCTTGGAACATATCACTCTAAATAATCCTAAAATCTCTGGTGTTATTATTAGTGA
CAACAAACACAATCTATTTTGTTCAACTTTACCCAATAATAAAGATCTTATTGCAACACCGATTCGTTCACGTTCTATTA
TAGGCCCCTATAATTTACCATTATTTGACCAGCCCGTTTACCTGATCCAGCAAAAAATGGGCAATTACCTTATAGGTATT
TTAGTTATTGCTTCTGTCTTAAAAAGTGAATTACAAACAGATAAAAATCAATCCACCTCTATAGCCCTATATAATGAATA
TGAGAAAAAAAATATCTTTCGTATTCGATATACTGAGCAAAATAAAAACTGGGTATTAAGCAATACGCAAGAAACTGACA
CACAATATACCCAATTAGGTCTCGTTGCTATAGAAAAACTACAAAGCATAAATGGTGTTTCTGTCGTTGTTTCTGAAAAC
AATAAAACTATCCTTCATAACTTTTGGTATAGTCAAACAATAACAATTCTTATTATTTTGATTTTTTCCTTTATTTTGTA
TGTCCTCATAAAAAACATGATGACCAAACGTTATTCATTACAAGGCGCAATAAAACTGGCTATTAAAAATGAGGAATTTT
ATCCTGTATACCAACCTTTGTTTGACTGTGATGAAGAACGATTCACAGGGGCTGAAGTATTATTGCGATGGGAAAATGAA
GACAGTCAAATCATTATGCCTGATTTTTTTATTGCTGAAGCAGAAGCTACCGGGTTAATTGTGCCAATTACACTTCAAAT
CATAGAAATTGCCTTCAAAGAATTTAGATCTCTGTTTGAAGAACGATCTTACTTTCACCTTGCATTTAACATTTCTGCAC
TACATTTCACAGATTCAGTTTTTTTCAATCATTTCCATAAGCTAATAGAAAAATATAGTATTTCACCGCATCAAATAATC
TTTGAAATTACCGAAAGAGAACTCCTCGATAAAAACGACACAACTTTTATCAATAAAATGCAAGAATTAAGGCAAGCTGG
TTTTTCACTTGCTGTTGATGATTATGGGACTGGCCATGCCAGCATTAGTTATTTGCAACACTTTCCTTTCAATTATTTAA
AAATTGATAAATTATTTGTTCAAGCAATTGGTTCTAATGATATTATCGAATCATTAAATGACGCCATTATCCAGATGGCA
AAAGGATTAAACTTAGTTACTATAGCAGAAGGCGTGGAAACAAAAGACCAAGCTAATTACCTGGCAAATAATGGTGTTCG
TTTACAACAAGGCTGGTATTATTCCAAAGGGCTATCCATTGCTGAATTAACAGCCTTGCTTAAAGGAGAAAAAATATGA

Upstream 100 bases:

>100_bases
TATTGGTTACCACCTCTTAACACAGATAAAAAAATTATTGGGAAATTAGCAGAAATCACATTAAACTCTATAGAAGAAGC
CTATAACAAAGCTCAAGGAT

Downstream 100 bases:

>100_bases
GGAATTATATTTTTTATGGTTTACTACTATTAATTGGTTTATCCCATCAAGGCTTTACTGCCCCAATGATGAAAAAAGGA
AGTTATTGGAAATGCGTAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MSKVIHKLSLFLFKKFKIIWILLTIGILISAFYANWNINQKRAYKDLKEVAINLSNNIDGFIEDLLQEIYALPVYGKKIV
DCKSDLYPFLEHITLNNPKISGVIISDNKHNLFCSTLPNNKDLIATPIRSRSIIGPYNLPLFDQPVYLIQQKMGNYLIGI
LVIASVLKSELQTDKNQSTSIALYNEYEKKNIFRIRYTEQNKNWVLSNTQETDTQYTQLGLVAIEKLQSINGVSVVVSEN
NKTILHNFWYSQTITILIILIFSFILYVLIKNMMTKRYSLQGAIKLAIKNEEFYPVYQPLFDCDEERFTGAEVLLRWENE
DSQIIMPDFFIAEAEATGLIVPITLQIIEIAFKEFRSLFEERSYFHLAFNISALHFTDSVFFNHFHKLIEKYSISPHQII
FEITERELLDKNDTTFINKMQELRQAGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMA
KGLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI

Sequences:

>Translated_532_residues
MSKVIHKLSLFLFKKFKIIWILLTIGILISAFYANWNINQKRAYKDLKEVAINLSNNIDGFIEDLLQEIYALPVYGKKIV
DCKSDLYPFLEHITLNNPKISGVIISDNKHNLFCSTLPNNKDLIATPIRSRSIIGPYNLPLFDQPVYLIQQKMGNYLIGI
LVIASVLKSELQTDKNQSTSIALYNEYEKKNIFRIRYTEQNKNWVLSNTQETDTQYTQLGLVAIEKLQSINGVSVVVSEN
NKTILHNFWYSQTITILIILIFSFILYVLIKNMMTKRYSLQGAIKLAIKNEEFYPVYQPLFDCDEERFTGAEVLLRWENE
DSQIIMPDFFIAEAEATGLIVPITLQIIEIAFKEFRSLFEERSYFHLAFNISALHFTDSVFFNHFHKLIEKYSISPHQII
FEITERELLDKNDTTFINKMQELRQAGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMA
KGLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI
>Mature_531_residues
SKVIHKLSLFLFKKFKIIWILLTIGILISAFYANWNINQKRAYKDLKEVAINLSNNIDGFIEDLLQEIYALPVYGKKIVD
CKSDLYPFLEHITLNNPKISGVIISDNKHNLFCSTLPNNKDLIATPIRSRSIIGPYNLPLFDQPVYLIQQKMGNYLIGIL
VIASVLKSELQTDKNQSTSIALYNEYEKKNIFRIRYTEQNKNWVLSNTQETDTQYTQLGLVAIEKLQSINGVSVVVSENN
KTILHNFWYSQTITILIILIFSFILYVLIKNMMTKRYSLQGAIKLAIKNEEFYPVYQPLFDCDEERFTGAEVLLRWENED
SQIIMPDFFIAEAEATGLIVPITLQIIEIAFKEFRSLFEERSYFHLAFNISALHFTDSVFFNHFHKLIEKYSISPHQIIF
EITERELLDKNDTTFINKMQELRQAGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMAK
GLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=284, Percent_Identity=35.2112676056338, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI87081743, Length=287, Percent_Identity=32.7526132404181, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1790496, Length=248, Percent_Identity=35.4838709677419, Blast_Score=162, Evalue=7e-41,
Organism=Escherichia coli, GI87081980, Length=258, Percent_Identity=36.4341085271318, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI87081845, Length=273, Percent_Identity=30.4029304029304, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1786507, Length=236, Percent_Identity=36.864406779661, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI226510982, Length=248, Percent_Identity=33.4677419354839, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081921, Length=262, Percent_Identity=35.1145038167939, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1787541, Length=235, Percent_Identity=31.4893617021277, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787055, Length=242, Percent_Identity=30.1652892561983, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788849, Length=243, Percent_Identity=26.7489711934156, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082096, Length=254, Percent_Identity=26.7716535433071, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1787410, Length=129, Percent_Identity=28.6821705426357, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 61257; Mature: 61125

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVIHKLSLFLFKKFKIIWILLTIGILISAFYANWNINQKRAYKDLKEVAINLSNNIDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCH
FIEDLLQEIYALPVYGKKIVDCKSDLYPFLEHITLNNPKISGVIISDNKHNLFCSTLPNN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCC
KDLIATPIRSRSIIGPYNLPLFDQPVYLIQQKMGNYLIGILVIASVLKSELQTDKNQSTS
CCEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
IALYNEYEKKNIFRIRYTEQNKNWVLSNTQETDTQYTQLGLVAIEKLQSINGVSVVVSEN
EEEEECCCCCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
NKTILHNFWYSQTITILIILIFSFILYVLIKNMMTKRYSLQGAIKLAIKNEEFYPVYQPL
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHH
FDCDEERFTGAEVLLRWENEDSQIIMPDFFIAEAEATGLIVPITLQIIEIAFKEFRSLFE
HCCCCCCCCCEEEEEEEECCCCEEECCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHH
ERSYFHLAFNISALHFTDSVFFNHFHKLIEKYSISPHQIIFEITERELLDKNDTTFINKM
CCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHEEEEEHHHHHCCCCCHHHHHHH
QELRQAGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMA
HHHHHCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KGLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI
CCCCEEEEECCCCCCHHHHHHHCCCEEEECCEEECCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SKVIHKLSLFLFKKFKIIWILLTIGILISAFYANWNINQKRAYKDLKEVAINLSNNIDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCH
FIEDLLQEIYALPVYGKKIVDCKSDLYPFLEHITLNNPKISGVIISDNKHNLFCSTLPNN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCC
KDLIATPIRSRSIIGPYNLPLFDQPVYLIQQKMGNYLIGILVIASVLKSELQTDKNQSTS
CCEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
IALYNEYEKKNIFRIRYTEQNKNWVLSNTQETDTQYTQLGLVAIEKLQSINGVSVVVSEN
EEEEECCCCCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
NKTILHNFWYSQTITILIILIFSFILYVLIKNMMTKRYSLQGAIKLAIKNEEFYPVYQPL
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHH
FDCDEERFTGAEVLLRWENEDSQIIMPDFFIAEAEATGLIVPITLQIIEIAFKEFRSLFE
HCCCCCCCCCEEEEEEEECCCCEEECCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHH
ERSYFHLAFNISALHFTDSVFFNHFHKLIEKYSISPHQIIFEITERELLDKNDTTFINKM
CCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHEEEEEHHHHHCCCCCHHHHHHH
QELRQAGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMA
HHHHHCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KGLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI
CCCCEEEEECCCCCCHHHHHHHCCCEEEECCEEECCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]