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The map label for this gene is rhtC [H]

Identifier: 148358798

GI number: 148358798

Start: 1462353

End: 1463012

Strand: Reverse

Name: rhtC [H]

Synonym: LPC_0680

Alternate gene names: 148358798

Gene position: 1463012-1462353 (Counterclockwise)

Preceding gene: 148358802

Following gene: 148358795

Centisome position: 40.91

GC content: 35.45

Gene sequence:

>660_bases
ATGGAACAATGGCATCAATTTACTCTACTATTCCCTTTAATCATTTTAGTTTTTATTTCATTAATCAGTCCTGGGCCAGA
TTTTGCTATCACAGTCAAAAACAGCTTGGCTTATTCCAGAAGGAGTGGTTTATTAACCGCGTTAGGAATTGCTTTGGGCA
GTTTGGTTCATATTAGTTACACTCTCCTTGGATTAGGCCTGTTTATTACCAAAACACCTATAATACTGCATATCATCCAA
TATCTAGGGGCTGGATACCTCTTTTATATTGGCCTTAAAAATCTTGGTGCCAAGCCAAATGCTGACCAAATAGGAAGTTA
TGCATCGTACAACGATTTAAAACCAAGTGAAGCTTTTCTCAATGGGTTTATAACGAACTTATTGAACCCCAAAGCCATGC
TCTTTTTTATCAGTTTGTTTTCAGTACTTATGCCCAGAGAAATTTCAATCCCCAATAAATTATTCCTGGCAATTATCCTT
TTTCTACAAACATTGTTATGGTTTTCTTTTGTTGCATTCAGTCTTTCTGGAAAAAATACGCGTACGAAATTTCAAAGAGT
TAGCTATTGGATTGAACGTATTACAGGTGTCATTTTAATTGCATTGGCATTAAAGTTATTATTAAGCCAATTAGGGTCTG
TTGATATTTCGCTCGCTTGA

Upstream 100 bases:

>100_bases
TAAACAATGTCTTATTAACTAAATGTAAAATTAAAAAAGAGCGCTTAAAAATTAGCTATGATATTGGCTGAAAAAACTTA
GCAAAAAACTTGGAGTCTTT

Downstream 100 bases:

>100_bases
GTCGAAAAGCCTTGATTTTCGAGCACCGTAGCGGAGCATACATAGAAGTATGTGAGTAGCGGAGCACAGAAAATCAAGGC
TTTTCGGCCAAGATAGTAGA

Product: LysE family transporter

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRRSGLLTALGIALGSLVHISYTLLGLGLFITKTPIILHIIQ
YLGAGYLFYIGLKNLGAKPNADQIGSYASYNDLKPSEAFLNGFITNLLNPKAMLFFISLFSVLMPREISIPNKLFLAIIL
FLQTLLWFSFVAFSLSGKNTRTKFQRVSYWIERITGVILIALALKLLLSQLGSVDISLA

Sequences:

>Translated_219_residues
MEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRRSGLLTALGIALGSLVHISYTLLGLGLFITKTPIILHIIQ
YLGAGYLFYIGLKNLGAKPNADQIGSYASYNDLKPSEAFLNGFITNLLNPKAMLFFISLFSVLMPREISIPNKLFLAIIL
FLQTLLWFSFVAFSLSGKNTRTKFQRVSYWIERITGVILIALALKLLLSQLGSVDISLA
>Mature_219_residues
MEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRRSGLLTALGIALGSLVHISYTLLGLGLFITKTPIILHIIQ
YLGAGYLFYIGLKNLGAKPNADQIGSYASYNDLKPSEAFLNGFITNLLNPKAMLFFISLFSVLMPREISIPNKLFLAIIL
FLQTLLWFSFVAFSLSGKNTRTKFQRVSYWIERITGVILIALALKLLLSQLGSVDISLA

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=204, Percent_Identity=30.3921568627451, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786522, Length=192, Percent_Identity=30.2083333333333, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788099, Length=202, Percent_Identity=30.1980198019802, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 24333; Mature: 24333

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRRSGLLTALGIALGSLVHISY
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLGLGLFITKTPIILHIIQYLGAGYLFYIGLKNLGAKPNADQIGSYASYNDLKPSEAFL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCHHHHCCCCCCCCCCHHHHHH
NGFITNLLNPKAMLFFISLFSVLMPREISIPNKLFLAIILFLQTLLWFSFVAFSLSGKNT
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RTKFQRVSYWIERITGVILIALALKLLLSQLGSVDISLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MEQWHQFTLLFPLIILVFISLISPGPDFAITVKNSLAYSRRSGLLTALGIALGSLVHISY
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLGLGLFITKTPIILHIIQYLGAGYLFYIGLKNLGAKPNADQIGSYASYNDLKPSEAFL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCHHHHCCCCCCCCCCHHHHHH
NGFITNLLNPKAMLFFISLFSVLMPREISIPNKLFLAIILFLQTLLWFSFVAFSLSGKNT
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RTKFQRVSYWIERITGVILIALALKLLLSQLGSVDISLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]