| Definition | Legionella pneumophila str. Corby chromosome, complete genome. |
|---|---|
| Accession | NC_009494 |
| Length | 3,576,470 |
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The map label for this gene is dacB [H]
Identifier: 148358677
GI number: 148358677
Start: 3098543
End: 3100336
Strand: Reverse
Name: dacB [H]
Synonym: LPC_0554
Alternate gene names: 148358677
Gene position: 3100336-3098543 (Counterclockwise)
Preceding gene: 148358676
Following gene: 148358680
Centisome position: 86.69
GC content: 43.48
Gene sequence:
>1794_bases ATGAAAAGGACGTTGACTGGGGCATTCATGTGGGCAGTATGGTCACTGTCATCTCATGCGGCAAGTATGCAGTTCGAGGT GGATAAATTAATTAATCGGCTAAACCCTCATGTGAACCTGGGGATAGTAGTGACCGATCTAACCTCGGGCGAGACGCTAT ATAAACGCAATGCCAATCGTTTGTATATTCCTGCCAGTAACATGAAGCTTTTTTCCGAGGCAGCGGCCCTGATGGCTTTG GGCCCAGACTACCAATTCAAGAATCAACTCAGTACGAGCGCCAATCAATTACAACAAGGTGTTTTGCACGGAAACTTGTA TTTACATCTCAGCGGCGATCCTTCGTTTAGCAGAGAAGATTTAAAGACGTTGCTTTCTTCACTCAAGGATTGGAATATCA CAACCATTCAAGGTAATGTGATCATTGACAGTAGCCTGATGTCCATTCCCGCCTATCCCCCAGGCTGGCTAACTTCTGAT TTATCTTATAGTTATGGTGCGCCAATAGCACCTTTGATGGTTGATTCCAACCGATTAACAATCACGGTCAACCCCGGGGC TAAAGCAGGCGCTCCTGCTATTGTTGAAGTAGATGATGGCGGCGGTACTATTAACCTGAATAATCAAGCGACCACAAAGG CAAGTGAGAAAGGGTGTGGTGTAGGGTTTTATTTGGATCCTGAGAACAATTTAACGGTAAGAGGCTGTGTTGGATTAGGG CAATGGGCTGTTCAGCAACGCATCGCTATAAAGAATCCTTTTGTTTATGCCCAGGGGATGATTGTGAGCGAGCTTGCCAA GTCTAATATTAAATTAAATGGACAGGTTTTGCTTGGAAGAGCGCCTGCTGGTACTTTATTAATTGCCACTCGCTATTCAA AGCCAATTTCCCAACTGATGGCAGATACTTTAAAACCTTCTGATAATTTATATGCTGATAGTTTGTACTTGCATGCTGCT GCCAAAATTAAGGGTAGTCCTGTAGATTGGAAGCAAGCACAGCCAGTAATTAAAAATTTTTTGCAGCAACAAACAGGAAT CGATTTAAAAGACTCGAATTTTACAGATGGTTCTGGATTATCACGTTATAATTTGGTAACTCCAGCGCAAACCATGGCGC TTTTAAAATTCTTGTATCAACGTTTCCCATTATCTTATGAATACATTGCTGCTTTACCCATCTCTGGTCGGGATGGTACT TTGCAAAAGCGGTTTAAAACCCCAAATCAACAAGGATTTGTGCGGGCCAAAACCGGGACGATGACGGGTATGAACAGTTT ATCCGGTTACTTGTATACTGCTAATGGCCATACCTTGGCTTTTGCTATGTATATCAATAGATTACCCGGAAAACCGGCTG GGCCAGGACGCCCATTATTAGACGCATTATGCACTTATTTCTTGCAGCAAAGCCCAACAAGCAGTCGACTGGCACGGGTA TTATCTCCCCACAGTCGCATTAAGTTCCAATTTAATCCTACACAAATTGAGTTACAGAGAGTTCATCAAGCCAAATGGAG GCGTTTGGAAACGGCAGTGAGGCAGGTCTTGAGAGGACAGGATGTGAATGTGGTTTACCGGGGCAATGAATTAATCGTGA CAGACAATCAGTCTAATGCGAATAGCGTTTGGAAAGCTTTACAATCAATTGGCAAGAAATATTCATTCGCTGTAGCCTTG TCTTCTAAAGTGATGCCTGTTACACCATCGGGAAAACCTTTGCTTCTTTGGGTGCAAGCACCTTTATCTGAAAATAAGGC AGAGAGAACCTGGATAATTCGGGAAGCGGTATAA
Upstream 100 bases:
>100_bases TATGATTAGCTTATCGGAACTAACTCAGAAATTGTCACTATGTATCAAACAATTCAAACTGGTTTATATTGTGAAATTCA ATGTTAAGGAAAATATTTAA
Downstream 100 bases:
>100_bases CCCGAGTTTGATAATTAAAAAAAAGACCAGCCTCGTATTACTAAAATGCAATGCGGGGCTAGTACAATCATTCCATAAGT TATGGATAAGATCAGTCGTT
Product: D-alanyl-D-alanine carboxypeptidase
Products: NA
Alternate protein names: DD-carboxypeptidase; DD-peptidase; D-alanyl-D-alanine endopeptidase; DD-endopeptidase; Penicillin-binding protein 4; PBP-4 [H]
Number of amino acids: Translated: 597; Mature: 597
Protein sequence:
>597_residues MKRTLTGAFMWAVWSLSSHAASMQFEVDKLINRLNPHVNLGIVVTDLTSGETLYKRNANRLYIPASNMKLFSEAAALMAL GPDYQFKNQLSTSANQLQQGVLHGNLYLHLSGDPSFSREDLKTLLSSLKDWNITTIQGNVIIDSSLMSIPAYPPGWLTSD LSYSYGAPIAPLMVDSNRLTITVNPGAKAGAPAIVEVDDGGGTINLNNQATTKASEKGCGVGFYLDPENNLTVRGCVGLG QWAVQQRIAIKNPFVYAQGMIVSELAKSNIKLNGQVLLGRAPAGTLLIATRYSKPISQLMADTLKPSDNLYADSLYLHAA AKIKGSPVDWKQAQPVIKNFLQQQTGIDLKDSNFTDGSGLSRYNLVTPAQTMALLKFLYQRFPLSYEYIAALPISGRDGT LQKRFKTPNQQGFVRAKTGTMTGMNSLSGYLYTANGHTLAFAMYINRLPGKPAGPGRPLLDALCTYFLQQSPTSSRLARV LSPHSRIKFQFNPTQIELQRVHQAKWRRLETAVRQVLRGQDVNVVYRGNELIVTDNQSNANSVWKALQSIGKKYSFAVAL SSKVMPVTPSGKPLLLWVQAPLSENKAERTWIIREAV
Sequences:
>Translated_597_residues MKRTLTGAFMWAVWSLSSHAASMQFEVDKLINRLNPHVNLGIVVTDLTSGETLYKRNANRLYIPASNMKLFSEAAALMAL GPDYQFKNQLSTSANQLQQGVLHGNLYLHLSGDPSFSREDLKTLLSSLKDWNITTIQGNVIIDSSLMSIPAYPPGWLTSD LSYSYGAPIAPLMVDSNRLTITVNPGAKAGAPAIVEVDDGGGTINLNNQATTKASEKGCGVGFYLDPENNLTVRGCVGLG QWAVQQRIAIKNPFVYAQGMIVSELAKSNIKLNGQVLLGRAPAGTLLIATRYSKPISQLMADTLKPSDNLYADSLYLHAA AKIKGSPVDWKQAQPVIKNFLQQQTGIDLKDSNFTDGSGLSRYNLVTPAQTMALLKFLYQRFPLSYEYIAALPISGRDGT LQKRFKTPNQQGFVRAKTGTMTGMNSLSGYLYTANGHTLAFAMYINRLPGKPAGPGRPLLDALCTYFLQQSPTSSRLARV LSPHSRIKFQFNPTQIELQRVHQAKWRRLETAVRQVLRGQDVNVVYRGNELIVTDNQSNANSVWKALQSIGKKYSFAVAL SSKVMPVTPSGKPLLLWVQAPLSENKAERTWIIREAV >Mature_597_residues MKRTLTGAFMWAVWSLSSHAASMQFEVDKLINRLNPHVNLGIVVTDLTSGETLYKRNANRLYIPASNMKLFSEAAALMAL GPDYQFKNQLSTSANQLQQGVLHGNLYLHLSGDPSFSREDLKTLLSSLKDWNITTIQGNVIIDSSLMSIPAYPPGWLTSD LSYSYGAPIAPLMVDSNRLTITVNPGAKAGAPAIVEVDDGGGTINLNNQATTKASEKGCGVGFYLDPENNLTVRGCVGLG QWAVQQRIAIKNPFVYAQGMIVSELAKSNIKLNGQVLLGRAPAGTLLIATRYSKPISQLMADTLKPSDNLYADSLYLHAA AKIKGSPVDWKQAQPVIKNFLQQQTGIDLKDSNFTDGSGLSRYNLVTPAQTMALLKFLYQRFPLSYEYIAALPISGRDGT LQKRFKTPNQQGFVRAKTGTMTGMNSLSGYLYTANGHTLAFAMYINRLPGKPAGPGRPLLDALCTYFLQQSPTSSRLARV LSPHSRIKFQFNPTQIELQRVHQAKWRRLETAVRQVLRGQDVNVVYRGNELIVTDNQSNANSVWKALQSIGKKYSFAVAL SSKVMPVTPSGKPLLLWVQAPLSENKAERTWIIREAV
Specific function: Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction [H]
COG id: COG2027
COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
Gene ontology:
Cell location: Periplasm (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S13 family [H]
Homologues:
Organism=Escherichia coli, GI1789573, Length=438, Percent_Identity=30.1369863013699, Blast_Score=212, Evalue=4e-56,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR000667 [H]
Pfam domain/function: PF02113 Peptidase_S13 [H]
EC number: =3.4.16.4 [H]
Molecular weight: Translated: 65573; Mature: 65573
Theoretical pI: Translated: 10.20; Mature: 10.20
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRTLTGAFMWAVWSLSSHAASMQFEVDKLINRLNPHVNLGIVVTDLTSGETLYKRNANR CCCCHHHHHHHHHHHHHCCHHHEEEEHHHHHHHCCCCEEEEEEEEECCCCCCCEECCCCE LYIPASNMKLFSEAAALMALGPDYQFKNQLSTSANQLQQGVLHGNLYLHLSGDPSFSRED EEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEECEEEEEECCCCCCCHHH LKTLLSSLKDWNITTIQGNVIIDSSLMSIPAYPPGWLTSDLSYSYGAPIAPLMVDSNRLT HHHHHHHHCCCCEEEEECCEEEECCHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEE ITVNPGAKAGAPAIVEVDDGGGTINLNNQATTKASEKGCGVGFYLDPENNLTVRGCVGLG EEECCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCC QWAVQQRIAIKNPFVYAQGMIVSELAKSNIKLNGQVLLGRAPAGTLLIATRYSKPISQLM HHHHHHHHHHCCCEEEECCHHHHHHHHCCCEECCEEEEECCCCCEEEEEECCCHHHHHHH ADTLKPSDNLYADSLYLHAAAKIKGSPVDWKQAQPVIKNFLQQQTGIDLKDSNFTDGSGL HHHCCCCCCEEECEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC SRYNLVTPAQTMALLKFLYQRFPLSYEYIAALPISGRDGTLQKRFKTPNQQGFVRAKTGT CEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCEEEEECCC MTGMNSLSGYLYTANGHTLAFAMYINRLPGKPAGPGRPLLDALCTYFLQQSPTSSRLARV CCCHHHCCCEEEECCCCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH LSPHSRIKFQFNPTQIELQRVHQAKWRRLETAVRQVLRGQDVNVVYRGNELIVTDNQSNA HCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCCH NSVWKALQSIGKKYSFAVALSSKVMPVTPSGKPLLLWVQAPLSENKAERTWIIREAV HHHHHHHHHHCCCEEEEEEECCCEEEECCCCCEEEEEEECCCCCCCCCEEEEEEECC >Mature Secondary Structure MKRTLTGAFMWAVWSLSSHAASMQFEVDKLINRLNPHVNLGIVVTDLTSGETLYKRNANR CCCCHHHHHHHHHHHHHCCHHHEEEEHHHHHHHCCCCEEEEEEEEECCCCCCCEECCCCE LYIPASNMKLFSEAAALMALGPDYQFKNQLSTSANQLQQGVLHGNLYLHLSGDPSFSRED EEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEECEEEEEECCCCCCCHHH LKTLLSSLKDWNITTIQGNVIIDSSLMSIPAYPPGWLTSDLSYSYGAPIAPLMVDSNRLT HHHHHHHHCCCCEEEEECCEEEECCHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEE ITVNPGAKAGAPAIVEVDDGGGTINLNNQATTKASEKGCGVGFYLDPENNLTVRGCVGLG EEECCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCC QWAVQQRIAIKNPFVYAQGMIVSELAKSNIKLNGQVLLGRAPAGTLLIATRYSKPISQLM HHHHHHHHHHCCCEEEECCHHHHHHHHCCCEECCEEEEECCCCCEEEEEECCCHHHHHHH ADTLKPSDNLYADSLYLHAAAKIKGSPVDWKQAQPVIKNFLQQQTGIDLKDSNFTDGSGL HHHCCCCCCEEECEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC SRYNLVTPAQTMALLKFLYQRFPLSYEYIAALPISGRDGTLQKRFKTPNQQGFVRAKTGT CEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCEEEEECCC MTGMNSLSGYLYTANGHTLAFAMYINRLPGKPAGPGRPLLDALCTYFLQQSPTSSRLARV CCCHHHCCCEEEECCCCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH LSPHSRIKFQFNPTQIELQRVHQAKWRRLETAVRQVLRGQDVNVVYRGNELIVTDNQSNA HCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCCH NSVWKALQSIGKKYSFAVALSSKVMPVTPSGKPLLLWVQAPLSENKAERTWIIREAV HHHHHHHHHHCCCEEEEEEECCCEEEECCCCCEEEEEEECCCCCCCCCEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2040429; 9278503; 2046551 [H]