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The map label for this gene is ykoW [H]

Identifier: 148358610

GI number: 148358610

Start: 3178315

End: 3179430

Strand: Direct

Name: ykoW [H]

Synonym: LPC_0484

Alternate gene names: 148358610

Gene position: 3178315-3179430 (Clockwise)

Preceding gene: 148358611

Following gene: 148358609

Centisome position: 88.87

GC content: 37.1

Gene sequence:

>1116_bases
ATGTCATTACTAAAGAAAACAAGAGAGCAGGATTACTCTATCCTGGTTACCACTCAAGACCAGCAAAGAAAGCGCCATTT
ACTTAATGTTATTTCCATAGAACTTTTAATTTTGGGTCTTTTGCTGATAATAACAAACCTCTGCCTGCTAAGAGCCTGGC
TTATAATCAGTATGTTAATCGTGGGCATTTTCATCTTGCTCGGAAATTTAATCTTAATCAAAAAGAACTTCAATCTGGCC
TTGAGTGGGCACATTTTGAATATTCTTGTGTTGTCTATCATCATTGGAGGCAATATCATCGTTGGAAAAACTACCATGTC
TTACCTGGGATGGTTCTATGTCTCTCCAATCGTTGCTTTTGCTACACTTGGATTAGCCGGGTTAGTCGTCTATGGTGTGC
TGGCGATTGGGGCAATGTTTCTTTTTGTATTCGAATTCTACATCCCCATCTATTCCATTTCTCAGGAATATGTATTTTTT
CTGGATAATACTAACCACCTGTTTATTTTTGCCCTTATTTTCACTGTTCTTTATCATTTTCTGGTTCAAAACTCACAATA
TGAATTGCTGTTAAAAGAGCAAAATTATCTGCTCATTGCCGATAAAGAAAAATTCCATTACCTTTCACATCACGATTCAT
TAACCAACTTACCCAACCGCCCCTACTTTCATGCTCATCTTCAGACCCTATTAGAGAATACTGACACTAAAAAGGAAGCC
ATTACTCTTTATTTTATGGATTTGGATAAATTCAAGCCCATCAATGACGAATACGGTCATGAGTTCGGTGATCAGCTTTT
ACTTTTAACCAGCAAGCGTTTGCAATCCTGCTTTAGGAAAAATGATTTTATAGCCCGACTGGGAGGAGATGAATTTACTG
CAATTATCGTTCATAAACCCCTTGATCACATTGCTGAGGCTCTAACTCTTAGAATTGAACAGGAATTTGAACAACCTTTT
GTTATAAATGGCCAGACCATTCATTGCACCATAAGCGTTGGGATAGCAAATTACCCGCGCAATGCAAAAAATGCGGAAGA
TTTGTTAAAATGGGCTGATAAAGCGATGTATGACAATAAAAGAAAAAAATATCAAACGCTTAAACAAACCTCTTAA

Upstream 100 bases:

>100_bases
AACCTCAACGTGGACAGTGTGGTTGTTTTTTAATCTATAATTGAATTAATAAACGAAATTAGCCCCATTGATTACCGGCC
AATGCGATTGAGGAAGGTGA

Downstream 100 bases:

>100_bases
CCAACATTCCTAATTTAATCAGTATGATTAGGCCTTCATTTTATAAAGCACAGGATGCAGCAATCTGACATTCACTTGAC
AATTAACTTTTACAACTTTA

Product: GGDEF/EAL domain-containing sensory box protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSLLKKTREQDYSILVTTQDQQRKRHLLNVISIELLILGLLLIITNLCLLRAWLIISMLIVGIFILLGNLILIKKNFNLA
LSGHILNILVLSIIIGGNIIVGKTTMSYLGWFYVSPIVAFATLGLAGLVVYGVLAIGAMFLFVFEFYIPIYSISQEYVFF
LDNTNHLFIFALIFTVLYHFLVQNSQYELLLKEQNYLLIADKEKFHYLSHHDSLTNLPNRPYFHAHLQTLLENTDTKKEA
ITLYFMDLDKFKPINDEYGHEFGDQLLLLTSKRLQSCFRKNDFIARLGGDEFTAIIVHKPLDHIAEALTLRIEQEFEQPF
VINGQTIHCTISVGIANYPRNAKNAEDLLKWADKAMYDNKRKKYQTLKQTS

Sequences:

>Translated_371_residues
MSLLKKTREQDYSILVTTQDQQRKRHLLNVISIELLILGLLLIITNLCLLRAWLIISMLIVGIFILLGNLILIKKNFNLA
LSGHILNILVLSIIIGGNIIVGKTTMSYLGWFYVSPIVAFATLGLAGLVVYGVLAIGAMFLFVFEFYIPIYSISQEYVFF
LDNTNHLFIFALIFTVLYHFLVQNSQYELLLKEQNYLLIADKEKFHYLSHHDSLTNLPNRPYFHAHLQTLLENTDTKKEA
ITLYFMDLDKFKPINDEYGHEFGDQLLLLTSKRLQSCFRKNDFIARLGGDEFTAIIVHKPLDHIAEALTLRIEQEFEQPF
VINGQTIHCTISVGIANYPRNAKNAEDLLKWADKAMYDNKRKKYQTLKQTS
>Mature_370_residues
SLLKKTREQDYSILVTTQDQQRKRHLLNVISIELLILGLLLIITNLCLLRAWLIISMLIVGIFILLGNLILIKKNFNLAL
SGHILNILVLSIIIGGNIIVGKTTMSYLGWFYVSPIVAFATLGLAGLVVYGVLAIGAMFLFVFEFYIPIYSISQEYVFFL
DNTNHLFIFALIFTVLYHFLVQNSQYELLLKEQNYLLIADKEKFHYLSHHDSLTNLPNRPYFHAHLQTLLENTDTKKEAI
TLYFMDLDKFKPINDEYGHEFGDQLLLLTSKRLQSCFRKNDFIARLGGDEFTAIIVHKPLDHIAEALTLRIEQEFEQPFV
INGQTIHCTISVGIANYPRNAKNAEDLLKWADKAMYDNKRKKYQTLKQTS

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=159, Percent_Identity=35.2201257861635, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786584, Length=194, Percent_Identity=29.3814432989691, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788956, Length=199, Percent_Identity=33.6683417085427, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788381, Length=158, Percent_Identity=32.9113924050633, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787262, Length=156, Percent_Identity=32.0512820512821, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081977, Length=177, Percent_Identity=34.4632768361582, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081881, Length=167, Percent_Identity=32.9341317365269, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=29.7619047619048, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787802, Length=156, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=28.4810126582279, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788085, Length=160, Percent_Identity=30, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081974, Length=152, Percent_Identity=32.8947368421053, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=157, Percent_Identity=32.484076433121, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 42742; Mature: 42611

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLKKTREQDYSILVTTQDQQRKRHLLNVISIELLILGLLLIITNLCLLRAWLIISMLI
CCHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIFILLGNLILIKKNFNLALSGHILNILVLSIIIGGNIIVGKTTMSYLGWFYVSPIVAF
HHHHHHHCCEEEEEECCCEEEHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHH
ATLGLAGLVVYGVLAIGAMFLFVFEFYIPIYSISQEYVFFLDNTNHLFIFALIFTVLYHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LVQNSQYELLLKEQNYLLIADKEKFHYLSHHDSLTNLPNRPYFHAHLQTLLENTDTKKEA
HHCCCCEEEEEECCCEEEEECCHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCCHHE
ITLYFMDLDKFKPINDEYGHEFGDQLLLLTSKRLQSCFRKNDFIARLGGDEFTAIIVHKP
EEEEEEEHHHCCCCCCHHCHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECC
LDHIAEALTLRIEQEFEQPFVINGQTIHCTISVGIANYPRNAKNAEDLLKWADKAMYDNK
HHHHHHHHHHHHHHHCCCCEEECCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCH
RKKYQTLKQTS
HHHHHHHHCCC
>Mature Secondary Structure 
SLLKKTREQDYSILVTTQDQQRKRHLLNVISIELLILGLLLIITNLCLLRAWLIISMLI
CHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIFILLGNLILIKKNFNLALSGHILNILVLSIIIGGNIIVGKTTMSYLGWFYVSPIVAF
HHHHHHHCCEEEEEECCCEEEHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHH
ATLGLAGLVVYGVLAIGAMFLFVFEFYIPIYSISQEYVFFLDNTNHLFIFALIFTVLYHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LVQNSQYELLLKEQNYLLIADKEKFHYLSHHDSLTNLPNRPYFHAHLQTLLENTDTKKEA
HHCCCCEEEEEECCCEEEEECCHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCCHHE
ITLYFMDLDKFKPINDEYGHEFGDQLLLLTSKRLQSCFRKNDFIARLGGDEFTAIIVHKP
EEEEEEEHHHCCCCCCHHCHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECC
LDHIAEALTLRIEQEFEQPFVINGQTIHCTISVGIANYPRNAKNAEDLLKWADKAMYDNK
HHHHHHHHHHHHHHHCCCCEEECCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCH
RKKYQTLKQTS
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]