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The map label for this gene is engD [H]

Identifier: 148358611

GI number: 148358611

Start: 3176881

End: 3177972

Strand: Direct

Name: engD [H]

Synonym: LPC_0485

Alternate gene names: 148358611

Gene position: 3176881-3177972 (Clockwise)

Preceding gene: 148358612

Following gene: 148358610

Centisome position: 88.83

GC content: 43.68

Gene sequence:

>1092_bases
ATGGGATTTAAATGTGGAATAGTAGGATTGCCTAATGTAGGGAAATCGACTCTTTTTAATGCATTGACTAAGGCTGGGAT
AGAGGCGGCCAATTACCCATTTTGTACCATTGAGCCCAATGTAGGTATCGTCACCGTTCCTGATTCAAGATTGGATAATT
TAAGCGACATAGTCAAGCCTCAGCAGGTGATTCATGCCACCATGCAATTTGTTGACATTGCGGGATTGGTAAAAGGCGCT
TCCAGTGGAGAAGGATTAGGAAATCAATTTTTGGCCAACATTAGAGAAACAGACGCTATTGCTCACGTCGTTCGCTGCTT
TGACAACTCGGACGTTGTTCATGTGGAGGGGCGAGTTGACCCCTTAAGTGACATAGAAGTGATTAATACAGAACTAGCAT
TAGCGGATATGGAGACATTGGAAAAATCGCTATTAAAAGTAGGGAAAAACAGTAAAAGTGGAAATAAAGAAGCCATTTTT
GAATTAAAAACTCTGGAAAAAATTAAAGCACATCTGGATACCGGATATCCTGTAAGAACACTTGAACTTACCCCTGAAGA
AGAACAGGTAAGCAAACGCCTTTTTCTATTAACGGCCAAACCGGTACTTTACATAGCCAATGTCGATGATAACGGCTATG
AGAATAACCCTCTCCTGGATAAAGTTAAGGCTCTGGCTTCCCAGGAAAATGCCAGCATAGTAGCCCTTTGTGCAGCAACA
GAAGCCGAGCTGGTTGAGCTGGATGAAGAAGACAGACAAGAGTTTATGGTAGATTTGGGACTTAGCGAGCCTGGATTAAA
TAAAGTGATCCGCGCCGGGTATGAATTGCTGGGATTGCAAACCTATTTCACCGCAGGAGTGAAAGAAGTAAGAGCCTGGA
CAATACGCAAGGGGGCCACAGCACCGCAAGCTGCCGGGGTCATTCATACCGACTTTGAGAAAGGATTCATCCGCGCGGAA
GTGATTTCTTACGAAGATTTTATTCGCTTTGGCGGAGAACAAGGCGCCAAAGAAGCTGGAAAATTGCGGCTTGAAGGCAA
GGAATATATTGTCTGTGACGGAGATGTCATGCATTTTCGCTTTAATGTTTAA

Upstream 100 bases:

>100_bases
TGCAATAGACAGAGGTATAGCGATAATACCTATAGTATTGTCAGGGGATATGGCCCGAGCAATGAATCAAGTAAACGCTT
AACATAATGAGGTATGACTC

Downstream 100 bases:

>100_bases
TAATTAGTATTCTGCAGCTGGTGATTTTTCAAGAATTGAACCAAGGAACCTCGATCCTCTATTGCTTCATCATTGCAAGT
AACCAGAGCATCGACCCAGA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSDIVKPQQVIHATMQFVDIAGLVKGA
SSGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVDPLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIF
ELKTLEKIKAHLDTGYPVRTLELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVKALASQENASIVALCAAT
EAELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGATAPQAAGVIHTDFEKGFIRAE
VISYEDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFRFNV

Sequences:

>Translated_363_residues
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSDIVKPQQVIHATMQFVDIAGLVKGA
SSGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVDPLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIF
ELKTLEKIKAHLDTGYPVRTLELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVKALASQENASIVALCAAT
EAELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGATAPQAAGVIHTDFEKGFIRAE
VISYEDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFRFNV
>Mature_362_residues
GFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSDIVKPQQVIHATMQFVDIAGLVKGAS
SGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVDPLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIFE
LKTLEKIKAHLDTGYPVRTLELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVKALASQENASIVALCAATE
AELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGATAPQAAGVIHTDFEKGFIRAEV
ISYEDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=46.4673913043478, Blast_Score=316, Evalue=3e-86,
Organism=Homo sapiens, GI58761502, Length=218, Percent_Identity=42.2018348623853, Blast_Score=166, Evalue=3e-41,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=67.7685950413223, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=33.0708661417323, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=365, Percent_Identity=44.3835616438356, Blast_Score=311, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=42.0054200542005, Blast_Score=271, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=36.2924281984334, Blast_Score=212, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6321649, Length=151, Percent_Identity=41.7218543046358, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24640873, Length=366, Percent_Identity=45.6284153005465, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24640877, Length=366, Percent_Identity=45.6284153005465, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24640875, Length=366, Percent_Identity=45.6284153005465, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=44, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24585318, Length=183, Percent_Identity=32.7868852459016, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39662; Mature: 39530

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSDIVKP
CCEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCH
QQVIHATMQFVDIAGLVKGASSGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVD
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIFELKTLEKIKAHLDTGYPVRT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
LELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVKALASQENASIVALCAAT
EEECCCHHHHCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECC
EAELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGAT
CHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCC
APQAAGVIHTDFEKGFIRAEVISYEDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFR
CCCCCCEEEECCCCCEEEEEECCHHHHHHHCCCCCCCHHCCEEECCCEEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSDIVKP
CEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCH
QQVIHATMQFVDIAGLVKGASSGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVD
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIFELKTLEKIKAHLDTGYPVRT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
LELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVKALASQENASIVALCAAT
EEECCCHHHHCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECC
EAELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGAT
CHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCC
APQAAGVIHTDFEKGFIRAEVISYEDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFR
CCCCCCEEEECCCCCEEEEEECCHHHHHHHCCCCCCCHHCCEEECCCEEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA