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The map label for this gene is cqsS [H]

Identifier: 148358527

GI number: 148358527

Start: 3260957

End: 3261304

Strand: Reverse

Name: cqsS [H]

Synonym: LPC_0398

Alternate gene names: 148358527

Gene position: 3261304-3260957 (Counterclockwise)

Preceding gene: 148358526

Following gene: 148358530

Centisome position: 91.19

GC content: 32.76

Gene sequence:

>348_bases
ATGTTACCATTCTTAAGTTTGTTTTTTAGACAGTTATATCGAATTCACGTTAATTTAATAAAAAATGCGCTTTATGTTAT
CGCAATGGCCCAGCGTGGGGAGATTAATATTTGGACTGAATCTGGCGATAAGTATCATTATTTGTATTTTAAAGACACAG
CAAAAGGGATGAGCAAACAACAATTAAATCGATTATTTAATCATTTCTATACTACTACCTTTATGGGAACAGGCATTGGT
TTATCATTTTGTAAATTGGTTATGAATGCGTTTGGTGGTGATATTGTTTGTGAGTCTAAAGAGGGCGAATACACTTTATT
TATACTGAGTTTTCCAGGCTCGGTTTAA

Upstream 100 bases:

>100_bases
CACAGAATAATTCTATTAATTTATCCACTCCAGACCTCTTGATTCTTATTTTTGTTCTTCGAAAAAACGAATAAGATCAC
AAATGGTCTGGTTTTTCAAT

Downstream 100 bases:

>100_bases
AATTGGTTTTCTGTTGAACATACCATCATTCGTCTTAAAAGACGTAAGGATGGTATTGAGTTAGAGAGCCCCTCTGATTC
TCTTCTGCTAGAGTTTGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: Cholerae quorum-sensing sensor [H]

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MLPFLSLFFRQLYRIHVNLIKNALYVIAMAQRGEINIWTESGDKYHYLYFKDTAKGMSKQQLNRLFNHFYTTTFMGTGIG
LSFCKLVMNAFGGDIVCESKEGEYTLFILSFPGSV

Sequences:

>Translated_115_residues
MLPFLSLFFRQLYRIHVNLIKNALYVIAMAQRGEINIWTESGDKYHYLYFKDTAKGMSKQQLNRLFNHFYTTTFMGTGIG
LSFCKLVMNAFGGDIVCESKEGEYTLFILSFPGSV
>Mature_115_residues
MLPFLSLFFRQLYRIHVNLIKNALYVIAMAQRGEINIWTESGDKYHYLYFKDTAKGMSKQQLNRLFNHFYTTTFMGTGIG
LSFCKLVMNAFGGDIVCESKEGEYTLFILSFPGSV

Specific function: Senses the quorum-sensing autoinducer CAI-1 ((S)-3- hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to luxU and luxO [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 13259; Mature: 13259

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPFLSLFFRQLYRIHVNLIKNALYVIAMAQRGEINIWTESGDKYHYLYFKDTAKGMSKQ
CCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCEEEEEEEECCCCCCCHH
QLNRLFNHFYTTTFMGTGIGLSFCKLVMNAFGGDIVCESKEGEYTLFILSFPGSV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCC
>Mature Secondary Structure
MLPFLSLFFRQLYRIHVNLIKNALYVIAMAQRGEINIWTESGDKYHYLYFKDTAKGMSKQ
CCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCEEEEEEEECCCCCCCHH
QLNRLFNHFYTTTFMGTGIGLSFCKLVMNAFGGDIVCESKEGEYTLFILSFPGSV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]