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The map label for this gene is luxN [H]

Identifier: 148358526

GI number: 148358526

Start: 3262268

End: 3263272

Strand: Reverse

Name: luxN [H]

Synonym: LPC_0396

Alternate gene names: 148358526

Gene position: 3263272-3262268 (Counterclockwise)

Preceding gene: 148358521

Following gene: 148358527

Centisome position: 91.24

GC content: 35.22

Gene sequence:

>1005_bases
ATGTCACAACTAAAAAGAATAGTGAAACATTTAGATGAATCAATGCAGCGTAGTTTGTCTAATTCCGCTCATCAATTGGT
TGCAGTAGGGGCAATAGCTTTTGTGGGGTTTCCTTTATTTTATGTTATTTGGGCTTTCTGGTTGCCTCAGCCTTATGAAA
ACCTGCCACTCCGTCTTATTGGAAGCTTTTTAGGTTTGGGATTGATGCTTACTCCTTATTGGCCATTAAAATGGAAGCAA
TATTTATCTTGGTATTGGTTTTTAACTCTTTTGTTTACTTTGCCATATTTTTTTACTTTTTTATTTTTAATGAATCAAGC
AAGCGTTATTTCTGCGATGTCTTTGTTGTGTGGTGTATTTTTACTTGTATTGCTCGTTGATTTATTAAGTTTATCCATTG
TGCTGATACTGGGGTTTAGTTTAGCCCTTGTAAGTTATTATCTTGTTTCTCCGCAAATGTATTTTGGAGAAGAGCATATA
CAAATGACATTGGTGATCATATTTACCATTATTGCAGGCTCTACTTTAAATTATAAAACAGCCATGTTGCAACAACAAAA
ATTGGCAGGCATGGCTGCTGCTGCAGGCATGATTGCTCATGAATTGCGCTCACCATTGTTAGGAATAAAGAGCGGCGCTC
AAGCTTTAGTCCAATATCTGCCAAGATTAATTGATGGTTATCAATTGGCTAAAAAACAAGAGTTAATATCTTCTCCTTTA
CGTGACAGATTATTGTTGCAACTTGGGGGAGTCAGCAATCGAATTGTTAATGAAATTGATTATGCTAATACGATCATTGA
TATGTTATTAGTCAAGGCAAGTCGCGATAATATTTTGCAAAATTGCATATTAGAGACTTGTTCTATAGCAGAATGTTTGT
CTGAGGCCATTACCAGATACCCATTTCAGTCACCAAGAGAAAGAACATTAATCACATGGACTGGTGATTTTCAATTTAAA
GGCTCCAAGTTGTTAATGCAGCATATTTTATTTAATTTAACGTGA

Upstream 100 bases:

>100_bases
GCATATCTCATGCACAATCCCTATATTTTATGATAGGCTTTTCCGGTAGATAAAGCGCTGAAAATCAGGGGCGTTTTTTA
GCTTGATTTAAGGATAAGGA

Downstream 100 bases:

>100_bases
ATTCGATATAACTGCTCAAACAACAGCCATAAAAGATCGTTGAATATTTAAAGAGGGCTTCTTTGGTTTAAGTGCATAAG
CAGCTAAACCGGCCAATATA

Product: sensor protein LuxN

Products: NA

Alternate protein names: Cholerae quorum-sensing sensor [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSQLKRIVKHLDESMQRSLSNSAHQLVAVGAIAFVGFPLFYVIWAFWLPQPYENLPLRLIGSFLGLGLMLTPYWPLKWKQ
YLSWYWFLTLLFTLPYFFTFLFLMNQASVISAMSLLCGVFLLVLLVDLLSLSIVLILGFSLALVSYYLVSPQMYFGEEHI
QMTLVIIFTIIAGSTLNYKTAMLQQQKLAGMAAAAGMIAHELRSPLLGIKSGAQALVQYLPRLIDGYQLAKKQELISSPL
RDRLLLQLGGVSNRIVNEIDYANTIIDMLLVKASRDNILQNCILETCSIAECLSEAITRYPFQSPRERTLITWTGDFQFK
GSKLLMQHILFNLT

Sequences:

>Translated_334_residues
MSQLKRIVKHLDESMQRSLSNSAHQLVAVGAIAFVGFPLFYVIWAFWLPQPYENLPLRLIGSFLGLGLMLTPYWPLKWKQ
YLSWYWFLTLLFTLPYFFTFLFLMNQASVISAMSLLCGVFLLVLLVDLLSLSIVLILGFSLALVSYYLVSPQMYFGEEHI
QMTLVIIFTIIAGSTLNYKTAMLQQQKLAGMAAAAGMIAHELRSPLLGIKSGAQALVQYLPRLIDGYQLAKKQELISSPL
RDRLLLQLGGVSNRIVNEIDYANTIIDMLLVKASRDNILQNCILETCSIAECLSEAITRYPFQSPRERTLITWTGDFQFK
GSKLLMQHILFNLT
>Mature_333_residues
SQLKRIVKHLDESMQRSLSNSAHQLVAVGAIAFVGFPLFYVIWAFWLPQPYENLPLRLIGSFLGLGLMLTPYWPLKWKQY
LSWYWFLTLLFTLPYFFTFLFLMNQASVISAMSLLCGVFLLVLLVDLLSLSIVLILGFSLALVSYYLVSPQMYFGEEHIQ
MTLVIIFTIIAGSTLNYKTAMLQQQKLAGMAAAAGMIAHELRSPLLGIKSGAQALVQYLPRLIDGYQLAKKQELISSPLR
DRLLLQLGGVSNRIVNEIDYANTIIDMLLVKASRDNILQNCILETCSIAECLSEAITRYPFQSPRERTLITWTGDFQFKG
SKLLMQHILFNLT

Specific function: Senses the quorum-sensing autoinducer CAI-1 ((S)-3- hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to luxU and luxO [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37881; Mature: 37749

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCEEEEEECCCEECHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQLKRIVKHLDESMQRSLSNSAHQLVAVGAIAFVGFPLFYVIWAFWLPQPYENLPLRLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
GSFLGLGLMLTPYWPLKWKQYLSWYWFLTLLFTLPYFFTFLFLMNQASVISAMSLLCGVF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVLLVDLLSLSIVLILGFSLALVSYYLVSPQMYFGEEHIQMTLVIIFTIIAGSTLNYKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHCCCCCHHH
AMLQQQKLAGMAAAAGMIAHELRSPLLGIKSGAQALVQYLPRLIDGYQLAKKQELISSPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
RDRLLLQLGGVSNRIVNEIDYANTIIDMLLVKASRDNILQNCILETCSIAECLSEAITRY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFQSPRERTLITWTGDFQFKGSKLLMQHILFNLT
CCCCCCCCEEEEEECCCEECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA