Click here to switch to the map view.

The map label for this gene is mrr [H]

Identifier: 148358355

GI number: 148358355

Start: 233982

End: 234959

Strand: Direct

Name: mrr [H]

Synonym: LPC_0219

Alternate gene names: 148358355

Gene position: 233982-234959 (Clockwise)

Preceding gene: 148358352

Following gene: 148358356

Centisome position: 6.54

GC content: 33.84

Gene sequence:

>978_bases
ATGAGAAGTCTTGGCTATACTTATTTCAACGAGTTGAATATTAAACGGAATTTTATGACGATACCAACTTATCAAGAATG
TATGCTACCTATGTTGAAAGTTCTTAAGGATAATAGCAATATAAAATCCACTAGATTAATAAGTCTGATGGGTGATTGGT
TTCATTTGTCAGATGATGAGCGTGAAGAGTTATTATCCAGTGGGAGAACAACAATATTAAGAACAAGAGTGCATTGGGCC
AAAGTATATCTGAAACAGGCTGGTTTAGTTGAATATCCTAAAAGAGGTTACGTTGCTATAACAGAGAAGGGGATTCAAGT
ATTGCAAAAAAATCCCTCGAACATTGATACTAATTATCTTAAAAAATTTCCTGATTTTATTAGATTTATTGAGAGATCAA
AAACAGAAAGTCAACAGGTTAGTAATAGTGAATATAGTGAAAATTATTCCCCTGATGAAGTATTGACTAGAACTTTTGAA
AGGATGAAAAACCAGACATGTGAGGAGCTTCTGGAAGTAATAAAGTCAAGTTCTCCTCAGTTTTTTGAAAAACTTGTAGT
GCAGGTTATAGTTAGTCTCGGATATGGTGGCTCACTACAGGAAGCAGGCCAAGCTATAGGAAAGTCTGGAGATGGGGGAG
TTGATGGGGTAATAAAGGAAGACAGGCTTGGTTTAGAGTTAATTTATTTACAGGCAAAATTGAAAAAAGATGACAAATAT
AATGTGGGGCGGCCTGACATACAAAAGTTTTATGGTGCTTTGCAGGGCAAGCAAGCTAAAAAGGGAATATTTATCACAAC
CACTGATTTTTCGAACGAAGCTAGAGAATATCTCAAAGTTATAGATAAAAAAATTATTCTATTGAATGGTAAGGAATTGA
TTGAATTAATGTGGGAATATAATATCGGATTAAATGTTTCTGCAACTTATGAAGTTAAAGATTTGGACTTGGATTTTTTT
AAAGAAGAACTCGAATAG

Upstream 100 bases:

>100_bases
AAACTACTTTGATAGGCAAAAGGTAGATCCATGTAAATAGATAAATAACGAATATTGTCTTTTTAAACTTGATTTATAGT
GATTCATTAAGAATAAACAA

Downstream 100 bases:

>100_bases
TATGTTACCTAAACTTTTTTAGGCTTGGGTAGTTGCTTACAAAAACTATTTATTCTTACACGTGGCGCACGTACAGGGTC
AGATCTTGCTCTTTGCCTTT

Product: Mrr restriction system protein

Products: NA

Alternate protein names: EcoKMrr [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRSLGYTYFNELNIKRNFMTIPTYQECMLPMLKVLKDNSNIKSTRLISLMGDWFHLSDDEREELLSSGRTTILRTRVHWA
KVYLKQAGLVEYPKRGYVAITEKGIQVLQKNPSNIDTNYLKKFPDFIRFIERSKTESQQVSNSEYSENYSPDEVLTRTFE
RMKNQTCEELLEVIKSSSPQFFEKLVVQVIVSLGYGGSLQEAGQAIGKSGDGGVDGVIKEDRLGLELIYLQAKLKKDDKY
NVGRPDIQKFYGALQGKQAKKGIFITTTDFSNEAREYLKVIDKKIILLNGKELIELMWEYNIGLNVSATYEVKDLDLDFF
KEELE

Sequences:

>Translated_325_residues
MRSLGYTYFNELNIKRNFMTIPTYQECMLPMLKVLKDNSNIKSTRLISLMGDWFHLSDDEREELLSSGRTTILRTRVHWA
KVYLKQAGLVEYPKRGYVAITEKGIQVLQKNPSNIDTNYLKKFPDFIRFIERSKTESQQVSNSEYSENYSPDEVLTRTFE
RMKNQTCEELLEVIKSSSPQFFEKLVVQVIVSLGYGGSLQEAGQAIGKSGDGGVDGVIKEDRLGLELIYLQAKLKKDDKY
NVGRPDIQKFYGALQGKQAKKGIFITTTDFSNEAREYLKVIDKKIILLNGKELIELMWEYNIGLNVSATYEVKDLDLDFF
KEELE
>Mature_325_residues
MRSLGYTYFNELNIKRNFMTIPTYQECMLPMLKVLKDNSNIKSTRLISLMGDWFHLSDDEREELLSSGRTTILRTRVHWA
KVYLKQAGLVEYPKRGYVAITEKGIQVLQKNPSNIDTNYLKKFPDFIRFIERSKTESQQVSNSEYSENYSPDEVLTRTFE
RMKNQTCEELLEVIKSSSPQFFEKLVVQVIVSLGYGGSLQEAGQAIGKSGDGGVDGVIKEDRLGLELIYLQAKLKKDDKY
NVGRPDIQKFYGALQGKQAKKGIFITTTDFSNEAREYLKVIDKKIILLNGKELIELMWEYNIGLNVSATYEVKDLDLDFF
KEELE

Specific function: Involved in the acceptance of foreign DNA which is modified. Restricts both adenine- and cytosine-methylated DNA [H]

COG id: COG1715

COG function: function code V; Restriction endonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790811, Length=316, Percent_Identity=33.5443037974684, Blast_Score=157, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011856
- InterPro:   IPR011335
- InterPro:   IPR007560 [H]

Pfam domain/function: PF04471 Mrr_cat [H]

EC number: NA

Molecular weight: Translated: 37464; Mature: 37464

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLGYTYFNELNIKRNFMTIPTYQECMLPMLKVLKDNSNIKSTRLISLMGDWFHLSDDE
CCCCCCHHHHHCCCEECEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHCCCCHH
REELLSSGRTTILRTRVHWAKVYLKQAGLVEYPKRGYVAITEKGIQVLQKNPSNIDTNYL
HHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCHHHH
KKFPDFIRFIERSKTESQQVSNSEYSENYSPDEVLTRTFERMKNQTCEELLEVIKSSSPQ
HHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FFEKLVVQVIVSLGYGGSLQEAGQAIGKSGDGGVDGVIKEDRLGLELIYLQAKLKKDDKY
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCC
NVGRPDIQKFYGALQGKQAKKGIFITTTDFSNEAREYLKVIDKKIILLNGKELIELMWEY
CCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHH
NIGLNVSATYEVKDLDLDFFKEELE
CCCCCEEEEEEEECCCHHHHHHHCC
>Mature Secondary Structure
MRSLGYTYFNELNIKRNFMTIPTYQECMLPMLKVLKDNSNIKSTRLISLMGDWFHLSDDE
CCCCCCHHHHHCCCEECEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHCCCCHH
REELLSSGRTTILRTRVHWAKVYLKQAGLVEYPKRGYVAITEKGIQVLQKNPSNIDTNYL
HHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCHHHH
KKFPDFIRFIERSKTESQQVSNSEYSENYSPDEVLTRTFERMKNQTCEELLEVIKSSSPQ
HHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FFEKLVVQVIVSLGYGGSLQEAGQAIGKSGDGGVDGVIKEDRLGLELIYLQAKLKKDDKY
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCC
NVGRPDIQKFYGALQGKQAKKGIFITTTDFSNEAREYLKVIDKKIILLNGKELIELMWEY
CCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHH
NIGLNVSATYEVKDLDLDFFKEELE
CCCCCEEEEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1650347; 7610040; 9278503 [H]